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Brain Structure and Function

Erschienen in:

01.03.2016 | Original Article

Tonic effects of the dopaminergic ventral midbrain on the auditory cortex of awake macaque monkeys

verfasst von: Ying Huang, Judith Mylius, Henning Scheich, Michael Brosch

Erschienen in: Brain Structure and Function | Ausgabe 2/2016

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Abstract

This study shows that ongoing electrical stimulation of the dopaminergic ventral midbrain can modify neuronal activity in the auditory cortex of awake primates for several seconds. This was reflected in a decrease of the spontaneous firing and in a bidirectional modification of the power of auditory evoked potentials. We consider that both effects are due to an increase in the dopamine tone in auditory cortex induced by the electrical stimulation. Thus, the dopaminergic ventral midbrain may contribute to the tonic activity in auditory cortex that has been proposed to be involved in associating events of auditory tasks (Brosch et al. Hear Res 271:66–73, 2011) and may modulate the signal-to-noise ratio of the responses to auditory stimuli.

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Titel: Tonic effects of the dopaminergic ventral midbrain on the auditory cortex of awake macaque monkeys
verfasst von: Ying Huang
Judith Mylius
Henning Scheich
Michael Brosch
Publikationsdatum: 01.03.2016
Verlag: Springer Berlin Heidelberg
Erschienen in: Brain Structure and Function / Ausgabe 2/2016
Print ISSN: 1863-2653
Elektronische ISSN: 1863-2661
DOI: https://doi.org/10.1007/s00429-014-0950-2

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