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Brain Structure and Function

Brain Structure and Function OnlineFirst articles

21.02.2019 | Original Article

Along-axon diameter variation and axonal orientation dispersion revealed with 3D electron microscopy: implications for quantifying brain white matter microstructure with histology and diffusion MRI

Tissue microstructure modeling of diffusion MRI signal is an active research area striving to bridge the gap between macroscopic MRI resolution and cellular-level tissue architecture. Such modeling in neuronal tissue relies on a number of …

19.02.2019 | Original Article

A framework for cortical laminar composition analysis using low-resolution T1 MRI images

The layer composition of the cerebral cortex represents a unique anatomical fingerprint of brain development, function, connectivity, and pathology. Historically, the cortical layers were investigated solely ex-vivo using histological means, but …

18.02.2019 | Original Article

Parcellation of motor cortex-associated regions in the human corpus callosum on the basis of Human Connectome Project data

The corpus callosum (CC) is the largest white matter structure of the brain and offers the structural basis for an intense interaction between both cerebral hemispheres. Especially with respect to the interaction of both motor cortices it shows a …

14.02.2019 | Original Article

Neurochemically distinct circuitry regulates locus coeruleus activity during female social stress depending on coping style

Stress-related psychiatric diseases are nearly twice as prevalent in women compared to men. We recently showed in male rats that the resident–intruder model of social stress differentially engages stress-related circuitry that regulates …

12.02.2019 | Original Article Open Access

Synaptic mechanisms underlying the intense firing of neocortical layer 5B pyramidal neurons in response to cortico-cortical inputs

In the neocortex, large layer 5B pyramidal neurons implement a high-density firing code. In contrast, other subtypes of pyramidal neurons, including those in layer 2/3, are functionally characterized by their sparse firing rate. Here, we …

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Brain Structure & Function offers free color in print and online for all its papers!

  • Brain Structure & Function publishes research that provides insight into brain structure−function relationships. Studies published here integrate data spanning from molecular, cellular, developmental, and systems architecture to the neuroanatomy of behavior and cognitive functions. BS&F does not publish purely clinical or neuropathological papers except in cases where the work actually contributes to the understanding of normal brain structure and function. Research on the peripheral nervous system is not the focus of BS&F.
  • Studies of the mammalian nervous system are central to the journal, yet coverage may range beyond this taxon. Methodologies include modern tracing, immunocytochemistry and neuroimaging as well as genetic methods, neuroinformatics (atlases, databases and internet tools), statistical techniques that support the integration of cellular and systems-level anatomical and functional data, and genetic/molecular/electrophysiological approaches to understanding brain organization.
  • The journal publishes full-length papers, short communications (maximum five printed pages including figures and references), reviews and letters to the editors that foster a vivid discussion of current topics.
  • Methods papers that fit into the mission of the journal are also welcome.
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