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Iron Deficiency 

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  1. Open Access 01.12.2024 | OriginalPaper

    Haem iron versus ferrous iron salts to treat iron deficiency anaemia in Gambian children: protocol for randomised controlled trial {1}

    In sub-Saharan Africa, conventional iron supplementation using ferrous salts has limited effectiveness, primarily due to impaired non-heme iron absorption caused by infections and inflammation. Although haem iron has greater bioavailability, it …

  2. Open Access 24.04.2024 | Online First

    Amino Acid Chelated Iron Versus Ferric Ammonium Citrate on Iron Status in Egyptian Children with Iron Deficiency Anemia: A Randomized Controlled Study

    Few studies have compared the relative effectiveness of different iron compounds on iron status in school-age children with iron deficiency anemia. The objective of this study was to compare the effect of iron amino acid chelated (AACI) …

  3. 19.04.2024 | Online First

    Pediculosis: An Unusual Cause of Iron Deficiency Anemia in Children

  4. Open Access 01.12.2024 | OriginalPaper

    Erythroferrone and hepcidin levels in children with iron deficiency anemia

    Anemia is defined as the decrease of hemoglobin (Hb), hematocrit (Htc), and erythrocyte count (RBC) below the value accepted as normal for a certain age and gender by two standard deviation value [ 1 ]. The issue of anemia, which has preserved its …

  5. 16.03.2024 | Online First

    Roles of ghrelin, hepcidin and HIF-2α in iron metabolism in iron deficiency anemia

    Iron deficiency (ID) is the most common nutritional disorder and the leading cause of nutritional anemia worldwide. Iron deficiency anemia (IDA) affects more than 1.2 billion people all over the world. Main reasons for iron deficiency are …

  6. 09.04.2024 | Online First

    Coexistence of Severe Iron Deficiency Anemia in Adolescent Girls with Exonic Variants Linked to Membranopathies

  7. Open Access 19.03.2024 | Online First

    Effect of Ferric Carboxymaltose Versus Low-Dose Intravenous Iron Therapy and Iron Sucrose on the Total Cost of Care in Patients with Iron Deficiency Anemia: A US Claims Database Analysis

    Iron deficiency is one of the most common causes of anemia. Iron is needed for many cellular functions, including erythropoiesis, and the resulting reduction in hemoglobin (Hgb) concentration due to the deficiency of iron may lead to symptoms such …

  8. Open Access 01.12.2024 | OriginalPaper

    Prevalence and predictors of iron deficiency anaemia among children with sickle cell disease in Dodoma, Tanzania: a cross-sectional study

    Sickle cell disease (SCD) is the world’s most severe and prevalent monogenic hemoglobin disorder [ 1 ]. It is characterized by mutation of the β globin gene at position 6 of chromosome number 11 which causes production of rigid β globin chain of a …

  9. Open Access 26.12.2023 | OriginalPaper

    Management of iron deficiency in women of childbearing age with oral iron intolerance: a prospective, randomised, controlled trial of three doses of an iron-whey-protein formulation

    Prospective RandomisEd study of women of Childbearing age with gastroInteStinal Intolerance to Oral iroN (PRECISION)

    Pharmacists are highly accessible healthcare professionals to women of childbearing age and have an important role to play in their care. Screening for oral iron intolerance amongst these women can identify a high risk cohort for iron deficiency.

  10. 28.10.2023 | OriginalPaper

    A randomized, controlled, open label non-inferiority trial of intravenous ferric carboxymaltose versus iron sucrose in patients with iron deficiency anemia in China

    Iron deficiency (ID) and ID anemia (IDA) pose significant public health concerns in China. Although iron sucrose (IS) treatment is well-established in the country, ferric carboxymaltose (FCM) offers the advantage of higher doses and fewer …

  11. 01.03.2024 | ReviewPaper

    Efficacy of Intravenous Iron in Patients with Heart Failure with Reduced Ejection Fraction and Iron Deficiency: A Systematic Review and Meta-Analysis of Randomized Control Trials

    Iron deficiency (ID) has been reported to occur in up to 50% of patients with heart failure with reduced ejection fraction (HFrEF) [ 1 – 4 ]. The etiology of ID in heart failure (HF) has been explained through multiple hypotheses, including …

  12. Open Access 01.12.2024 | OriginalPaper

    Reported outcomes in patients with iron deficiency or iron deficiency anemia undergoing major surgery: a systematic review of outcomes

    The World Health Organization (WHO) defines anemia as hemoglobin (Hb) levels <13.0 g/dL in men and <12.0 g/dL in women [ 1 ]. Iron deficiency (ID) is still the top-ranking cause of anemia in the general population worldwide [ 2 ]. In preoperative …

  13. 11.12.2023 | ReviewPaper

    The role of TMPRSS6 gene polymorphism in iron resistance iron deficiency anaemia (IRIDA): a systematic review

    Iron resistance iron deficiency anaemia is a rare autosomal recessive disorder characterized by hypochromic microcytic anaemia, low transferrin saturation and inappropriately high hepcidin levels. The aetiology of this condition is rooted in …

  14. Open Access 01.12.2024 | OriginalPaper

    Iron deficiency at birth and risk of hidden hearing loss in infants modification by socioeconomic status: mother-newborn cohort in Shenyang, China

    Iron deficiency (ID) is the most common form of micronutrient deficiency, and ID affects more than 2 billion people around the world [ 1 ]. ID is the main cause of anemia. Anemia remains a major public health problem, especially for children and …

  15. 17.02.2024 | OriginalPaper

    Transferrin Saturation, Serum Ferritin, and C-Reactive Protein vs. Serum Ferritin for an optimal Iron Deficiency Diagnosis in Candidates for Bariatric Surgery

    Iron is involved in various physiological processes; it's homeostasis is rigorously regulated; and its reserves adjust to the body’s needs through the increase or reduction of its absorption through hepcidin, which is responsible for limiting or …

  16. 06.12.2023 | Letter

    Iron-Refractory Iron Deficiency Anemia with Novel TMPRSS6 Mutation

  17. Open Access 01.12.2024 | OriginalPaper

    Acceptability of IV iron treatment for iron deficiency anaemia in pregnancy in Nigeria: a qualitative study with pregnant women, domestic decision-makers, and health care providers

    Anaemia in pregnancy (AIP) is a condition of public health significance with a prevalence of 36% globally, 41% in Africa, [ 1 ] and 25–45% in Nigeria [ 2 ]. Iron deficiency anaemia (IDA) accounts for 50–75% of AIP and is caused by insufficient iron

  18. Open Access 01.12.2024 | OriginalPaper

    Cost-effectiveness analysis of parenteral iron therapy compared to oral iron supplements in managing iron deficiency anemia among pregnant women

    Maternal anemia is a major public health concern in India, with a prevalence rate of 52.2% among pregnant women aged 15–49 years, as indicated by NFHS 05 data (HB levels < 11.0 g/dl) [ 1 ]. The association of anemia among pregnant women with …

  19. 05.12.2023 | Online First

    Effect of Iron Polymaltose Complex Prophylaxis on Frequency of Iron Deficiency and Iron Deficiency Anemia

    Iron is a crucial micronutrient for the human body, especially in the developing children. It has critical physiological roles such as oxygen transport to tissues, DNA synthesis, cellular proliferation, and activation of many enzymes [ 1 , 2 ]. As …

  20. Open Access 01.12.2024 | OriginalPaper

    Prevalence of iron deficiency in patients admitted to a geriatric unit: a multicenter cross-sectional study

    In addition to its key role in the synthesis of hemoglobin (Hb) and oxygen transport, iron is an essential element in many physiological processes such as energy metabolism, cardiac and peripheral muscle function [ 1 ]. Therefore, even though iron

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