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40637 Suchergebnisse für:

Mild Cognitive Impairment 

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  1. Open Access 19.04.2024 | Online First

    The Role of Cognitive Reserve in Protecting Cerebellar Volumes of Older Adults with mild Cognitive Impairment

    The present study aims to investigate the relationship between cerebellar volumes and cognitive reserve in individuals with Mild Cognitive Impairment (MCI). A description of proxies of cerebellar cognitive reserve in terms of different volumes …

  2. 17.04.2024 | Online First

    Growth-Associated Protein 43 and Tensor-Based Morphometry Indices in Mild Cognitive Impairment

    Growth-associated protein 43 (GAP-43) is found in the axonal terminal of neurons in the limbic system, which is affected in people with Alzheimer’s disease (AD). We assumed GAP-43 may contribute to AD progression and serve as a biomarker. So, in a …

  3. 20.04.2024 | Online First

    Establishment of a mild cognitive impairment risk model in middle-aged and older adults: a longitudinal study

    Dementia is a group of symptoms with cognitive impairment at its core, accompanied by a decline in social abilities that is severe enough to interfere with one’s activities of daily living and social autonomy [ 1 ]. Alzheimer’s disease is the main …

  4. Open Access 01.12.2024 | Letter

    Pathophysiological subtypes of mild cognitive impairment due to Alzheimer’s disease identified by CSF proteomics

  5. 24.01.2024 | ReviewPaper

    Mild cognitive impairment in Huntington’s disease: challenges and outlooks

    Although Huntington's disease (HD) has classically been viewed as an autosomal-dominant inherited neurodegenerative motor disorder, cognitive and/or behavioral changes are predominant and often an early manifestation of disease. About 40% of …

  6. Open Access 01.12.2024 | OriginalPaper

    Prefrontal intra-individual ERP variability and its asymmetry: exploring its biomarker potential in mild cognitive impairment

    The worldwide trend of demographic aging highlights the progress made in healthcare over the last century [ 1 ]. Nonetheless, this aging population encounters diverse health issues, notably Alzheimer’s Disease (AD), pronounced in those aged 65 or …

  7. Open Access 02.04.2024 | Online First

    Long-acting exenatide does not prevent cognitive decline in mild cognitive impairment: a proof-of-concept clinical trial

    Alzheimer’s disease (AD) represents the most common chronic neurodegenerative disorder, accounting for ~ 60–70% of all forms of dementia [ 1 ]. AD has a global overall prevalence of 3.9% in people ≥ 60 years [ 2 ] with over 43.8 million people …

  8. Open Access 01.12.2024 | OriginalPaper

    Resistance training's impact on blood biomarkers and cognitive function in older adults with low and high risk of mild cognitive impairment: a randomized controlled trial

    Cognitive decline is a natural part of aging and can have a significant impact on an individual's quality of life and ability to live independently [ 1 ]. When objective evidence of cognitive impairment is present, the terminology employed …

  9. Open Access 25.03.2024 | Online First

    Real-life management of patients with mild cognitive impairment: an Italian survey

    Mild cognitive impairment (MCI) is a neurological construct that refers to a condition in which an objective cognitive impairment on neuropsychological tests is present in the absence of significant impact on daily living activities. MCI …

  10. 02.04.2024 | Online First

    Visual Event-Related Potentials under External Emotional Stimuli as Early Signs for Mild Cognitive Impairment

    A ge related diseases are becoming more and more prominent worldwide due to the increased life expectancy. Alzheimer’s Disease (AD), the leading cause of dementia, accounts for 60–80% of all cases and is expected to influence 139 million population …

  11. Open Access 02.04.2024 | Online First

    Economic Impact of Progression from Mild Cognitive Impairment to Alzheimer Disease in the United States

    Alzheimer disease (AD) symptoms and severity are variable and range from a prodromal stage to late-stage dementia. Among individuals with dementia, mild cognitive impairment (MCI) is the first symptomatic stage on this non-linear continuum ( 1 , 2 …

  12. 10.03.2024 | Online First

    Erratum to: Education as Risk Factor of Mild Cognitive Impairment: The Link to the Gut Microbiome

  13. Open Access 01.12.2024 | OriginalPaper

    Informal carers’ experiences in everyday life and the use of digital assistive technology for time management in persons with dementia or mild cognitive impairment

    Older adults with dementia or mild cognitive impairments (MCI) may experience symptoms such as forgetfulness, communication difficulties, confusion, changes in mood or behavior, and challenges in carrying out familiar tasks [ 1 ]. These symptoms …

  14. Open Access 01.12.2024 | OriginalPaper

    Feasibility and usefulness of cognitive monitoring using a new home-based cognitive test in mild cognitive impairment: a prospective single arm study

    Mild cognitive impairment (MCI) indicates existence of objective cognitive impairments without limitation in activities of daily living. The risk of dementia is increased in MCI subjects, with clinical progression rates ranging from 10 to 15% …

  15. 26.04.2024 | Online First

    The prevalence of mild cognitive impairment in breast cancer patients receiving chemotherapy according to the criteria of the National Institute on Aging-Alzheimer’s Association (NIA-AA)

    Over the past decades, more and more women survive breast cancer due to earlier detection of the disease and better treatment options [ 1 ]. Current treatment options consist of surgery with various combinations of radiation and systemic or …

  16. Open Access 01.12.2024 | ReviewPaper

    Risk of conversion to mild cognitive impairment or dementia among subjects with amyloid and tau pathology: a systematic review and meta-analysis

    Affecting 55 million people worldwide, dementia is one of the leading causes of years spent with disability and one of the costliest long-term illnesses in society. The most common cause of dementia is Alzheimer's disease (AD), responsible for …

  17. 12.01.2024 | OriginalPaper

    Identifying Leukoaraiosis with Mild Cognitive Impairment by Fusing Multiple MRI Morphological Metrics and Ensemble Machine Learning

    Leukoaraiosis (LA) is strongly associated with impaired cognition and increased dementia risk. Determining effective and robust methods of identifying LA patients with mild cognitive impairment (LA-MCI) is important for clinical intervention and …

  18. Open Access 01.12.2024 | OriginalPaper

    Determining optimal cutoff scores of Cognitive Abilities Screening Instrument to identify dementia and mild cognitive impairment in Taiwan

    Determining the cognitive status of elderly individuals can be exceedingly difficult when dealing with early-stage dementia [ 1 ]. Cognitive assessments play a key role in the diagnosis of dementia and its prodromal stage, mild cognitive impairment

  19. Open Access 04.03.2024 | OriginalPaper

    Validation of the Slovenian version of the Montreal Cognitive Assessment Scale as a screening tool for the detection of mild cognitive impairment

    Mild cognitive impairment (MCI) is characterised by objective cognitive deficits with mainly preserved functional activities and not meeting criteria for clinically probable dementia [ 1 ]. The risk of progression from MCI to dementia has been …

  20. Open Access 01.12.2024 | OriginalPaper

    The use of individual-based FDG-PET volume of interest in predicting conversion from mild cognitive impairment to dementia

    The diagnosis of Alzheimer’s disease (AD) includes positive findings of amyloid and tau biomarkers [ 1 ]. Currently, AD can be diagnosed at the mild cognitive impairment (MCI) and even cognitively unimpaired stage with positive amyloid and tau …

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e.Medpedia

Vaskuläre kognitive Beeinträchtigung und Demenz

Klinische Neurologie
Der Begriff vaskuläre kognitive Beeinträchtigung („vascular cognitive impairment“, VCI) wurde zu Beginn der 2000er-Jahre eingeführt und wird mittlerweile international statt der alleinigen Verwendung des Begriffs vaskuläre Demenz vorgeschlagen. Darunter versteht man das gesamte Spektrum von vaskulären Gehirnerkrankungen (ischämisch oder hämorrhagisch), die zu kognitiver Beeinträchtigung beitragen: von subjektiver kognitiver Beeinträchtigung, nachgewiesener milder kognitiver Beeinträchtigung („mild cognitive impairment“) bis hin zu vaskulärer Demenz. Viele Literaturquellen beziehen sich jedoch (noch) auf den alleinigen Terminus der vaskulären Demenz, sodass in diesem Kapitel vielfach darauf Bezug genommen werden muss.

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