Skip to main content
230 Suchergebnisse für:

Niclosamid 

sortieren nach |
"Aktualität" sortiert die Ergebnisse nach Publikationsdatum. "Relevanz" berücksichtigt auch noch andere Faktoren wie zum Beispiel die Häufigkeit der Suchbegriffe im Text.
  1. Open Access 07.06.2023 | ReviewPaper

    Repurposing Niclosamide as a plausible neurotherapeutic in autism spectrum disorders, targeting mitochondrial dysfunction: a strong hypothesis

    Autism Spectrum Disorders (ASD) are a complex set of neurodevelopmental manifestations which present in the form of social and communication deficits. Affecting a growing proportion of children worldwide, the exact pathogenesis of this disorder is …

  2. 01.05.2023 | News

    Niclosamide overdose

    Bull's eye maculopathy and drug toxicity following accidental exposure: case report
  3. Open Access 01.12.2023 | OriginalPaper

    Presumed veterinary niclosamide-induced retinal toxicity in a human: a case report

    Niclosamide has been commonly prescribed for the treatment of intestinal parasite infections for several decades. This drug kills tapeworms by inhibiting oxidative phosphorylation in the mitochondria and anaerobic adenosine triphosphate (ATP) …

  4. Open Access 01.12.2023 | OriginalPaper

    Niclosamide from an anthelmintic drug to a promising adjuvant therapy for diabetic kidney disease: randomized clinical trial

    Diabetic kidney disease (DKD) develops in approximately 40% of patients with type 2 diabetes and is associated with significant mortality [ 1 ]. Diabetic kidney disease is defined clinically by persistent elevated urinary albumin creatinine ratio …

  5. 27.03.2021 | Niclosamide | OriginalPaper

    Improved Endothelium-Dependent Relaxation of Thoracic Aorta in Niclosamide-Treated Diabetic Rats

    Diabetes‐induced endothelial dysfunction is critical for the development of diabetic cardiovascular complications. The aim of this study was to investigate the effect of niclosamide (Nic) on vascular endothelial dysfunction in streptozotocin …

  6. 22.11.2021 | OriginalPaper

    Niclosamide downregulates LOX-1 expression in mouse vascular smooth muscle cells and changes the composition of atherosclerotic plaques in ApoE−/− mice

    Genetic lineage tracing studies have shown that phenotypic switching of vascular smooth muscle cells (VSMCs) results in less-differentiated cells, including macrophage-like cells that lack traditional VSMC markers. This switching contributes to …

  7. Open Access 01.12.2021 | OriginalPaper

    Targeting S100A4 with niclosamide attenuates inflammatory and profibrotic pathways in models of amyotrophic lateral sclerosis

    Amyotrophic lateral sclerosis (ALS) is a late-onset neurodegenerative disease characterized by progressive loss of motor neurons in the brain and spinal cord. It is the most common form of motor neuron disease [ 6 ], with an onset occurring at …

  8. Open Access 01.12.2021 | OriginalPaper

    Niclosamide suppresses the expansion of follicular helper T cells and alleviates disease severity in two murine models of lupus via STAT3

    Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune disease, with manifestations in multiple organ systems [ 1 ]. Damage to tissues in SLE results from the production of autoantibodies and immune complexes, mediated by the interplay …

  9. Open Access 25.07.2020 | OriginalPaper

    Combined effects of niclosamide and temozolomide against human glioblastoma tumorspheres

    Patients with glioblastoma (GBM), the most common type of primary brain tumor, have a poor prognosis, with a median overall survival of about 17.5 months in Korea (Kim et al. 2017a ). Standard treatments in patients with GBM include chemotherapy …

  10. Open Access 24.08.2019 | OriginalPaper

    Effects of salinomycin and niclosamide on small cell lung cancer and small cell lung cancer circulating tumor cell lines

    Tumor dissemination and recurrence is attributed to highly resistant cancer stem cells (CSCs) which may constitute a fraction of circulating tumor cells (CTCs). Small cell lung cancer (SCLC) constitutes a suitable model to investigate the relation …

  11. 07.08.2018 | ReviewPaper

    Current status of androgen receptor-splice variant 7 inhibitor niclosamide in castrate-resistant prostate-cancer

    Castrate-Resistant Prostate-Cancer (CRPC) is one of the most common malignancies occurring in men. Unfortunately, even if several recently approved agents clinically improved the outcome of CRPC patients, none of these is curative especially for a …

  12. 07.06.2018 | OriginalPaper

    Niclosamide as an adjuvant to etanercept in treatment patients with active rheumatoid arthritis: an 8-week randomized controlled pilot study

    This study designed to identify the therapeutic efficacy of niclosamide (NCL) in Iraqi patients suffering from active rheumatoid arthritis (RA) who were using etanercept (ETN) for more than 3 months and still had high or moderate active RA. One …

  13. Open Access 01.12.2018 | OriginalPaper

    Phase II trial to investigate the safety and efficacy of orally applied niclosamide in patients with metachronous or sychronous metastases of a colorectal cancer progressing after therapy: the NIKOLO trial

    Colorectal cancer (CRC) is the second most common cause of all cancer deaths in Europe and the Western world with a lifetime risk of approximately 5% [ 1 ]. Despite the implementation of early detection programs about 20–25% of all patients have …

  14. 2021 | OriginalPaper | Buchkapitel

    Konjunktivitis (engl. conjunctivitis)

    ICD-10-Code …

    verfasst von:
    Henrike Westekemper, Alexander A. Bialasiewicz,
    Erschienen in:
    Entzündliche Augenerkrankungen (2021)
  15. Open Access 01.12.2016 | OriginalPaper

    Niclosamide induced cell apoptosis via upregulation of ATF3 and activation of PERK in Hepatocellular carcinoma cells

    Hepatocellular carcinoma (HCC) is one of the most common and aggressive human malignancies in the world [ 1 ]. It is a major public health issue worldwide according to epidemiological data, and the incidence is high in East Asia.

  16. 01.12.2015 | OriginalPaper

    Niclosamide inhibits the inflammatory and angiogenic activation of human umbilical vein endothelial cells

    Vascular endothelial cells play an important role in the regulation of vascular tone, vascular permeability, angiogenesis and vascular inflammatory response [ 1 , 2 ].

  17. 26.01.2016 | OriginalPaper

    Combined niclosamide with cisplatin inhibits epithelial-mesenchymal transition and tumor growth in cisplatin-resistant triple-negative breast cancer

    Women with triple-negative breast cancer have worse prognosis compared to other breast cancer subtypes. Acquired drug resistance remains to be an important reason influencing triple-negative breast cancer treatment efficacy. A prevailing theory …

  18. 01.04.2015 | OriginalPaper

    Inhibitory effects of niclosamide on inflammation and migration of fibroblast-like synoviocytes from patients with rheumatoid arthritis

    Rheumatoid arthritis (RA) is a common chronic inflammatory disease that may cause synovial inflammation, hyperplasia of the synovial tissues, and joint damage [ 1 ]. Fibroblast-like synoviocytes (FLS) are key players in the pathophysiological …

  19. 2020 | OriginalPaper | Buchkapitel

    Zestoden

    Zestoden (Bandwürmer) bestehen aus Kopf (Skolex) und Gliedern (Proglottiden) und gehören zusammen mit den Trematoden zu den Plattwürmern (Plathelminthes). Der Kopf ist mit Saugnäpfen behaftet, daran schließt sich eine ungegliederte Wachstumszone …

    verfasst von:
    Ralf Ignatius, Gerd-Dieter Burchard
    Erschienen in:
    Medizinische Mikrobiologie und Infektiologie (2020)
  20. 21.03.2015 | OriginalPaper

    In vitro and in vivo anthelmintic activity of seed extract of Coriandrum sativum compared to Niclosamid against Hymenolepis nana infection

    Phytotherapy can be an alternative for the control of gastrointestinal parasites in human and animals. Coriander (Coriandrum sativum L.) is a medicinal plant which grown as a spice crop all over the world. The seeds of this plant have been used to …

Suchergebnisse filtern:

e.Medpedia

Parasitosen und exotoxinbedingte Erkrankungen des Gehirns

Klinische Neurologie
In Deutschland sind Parasitosen und die Vergiftung mit Exotoxinen eine Rarität. Gerade daher werden diese Erkrankungen nicht selten zu spät erkannt. Durch die vermehrte Reiseaktivität sind Parasitosen wie die zerebrale Malaria, Zystizerkose und auch Botulismus in die Differenzialdiagnose mit einzubeziehen.

weitere e.Medpedia Einträge

Suchoperatoren:

„ ... ... “ Findet Dokumente mit genau dieser Wortgruppe in exakt dieser Schreibweise und Reihenfolge (z.B., "rheumatische Beschwerden").
AND / UND Findet Dokumente, in denen beide Begriffe zusammen vorkommen (z.B., alkohol UND demenz).
OR / ODER Findet Dokumente, in denen einer der beiden oder beide Begriffe vorkommen (z.B., hiv ODER aids).
Leerzeichen Findet Dokumente, in denen alle Begriffe vorkommen. Der Leerschritt wird als UND interpretiert (z.B., isolierte systolische hypertonie).
NOT / NICHT Findet Dokumente, in denen der Begriff nach NOT nicht vorkommt (z.B., sars NOT sars-cov-2).
COUNT(...)>n Findet Dokumente, in denen der gesuchte Begriff mehr als n mal vorkommt. n steht für eine beliebige Anzahl (z.B., COUNT(mammakarzinom)>8).
NEAR(..., ..., ) Findet Dokumente, in denen beide Begriffe in beliebiger Reihenfolge innerhalb von maximal n Worten zueinander stehen. Empfehlung: wählen Sie zwischen 15 und 30 als maximale Wortanzahl (z.B., NEAR(covid, diabetes,20)).
* Findet Dokumente, in denen der Begriff in Wortvarianten vorkommt, wobei diese VOR, HINTER oder VOR und HINTER dem Suchbegriff anschließen können (z.B., thrombose*, *thrombose, *thrombose*).
? Findet Dokumente mit dem Suchbegriff in verschiedenen Schreibweisen, hier mit s oder z, also organisation und organization. Das ? steht für eine einzige Stelle (z.B., organi?ation).
& + - Sonderzeichen werden als UND interpretiert (z.B., Diagnose + Therapie).

Sie können Operatoren mit Ihrer Suchanfrage kombinieren, um diese noch präziser einzugrenzen.

Fahren Sie mit der Maus über den Suchoperator, um eine Erklärung seiner Funktionsweise anzuzeigen.