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01.12.2014 | Intravascular Imaging (E Regar and U Landmesser, Section Editors) | Ausgabe 12/2014

Toward Clinical μOCT—A Review of Resolution-Enhancing Technical Advances

Zeitschrift:: Current Cardiovascular Imaging Reports > Ausgabe 12/2014

Autoren:: Kengyeh K. Chu, Giovanni J. Ughi, Linbo Liu, Guillermo J. Tearney

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Wichtige Hinweise

This article is part of the Topical Collection on Intravascular Imaging

Abstract

Intravascular optical coherence tomography (IVOCT) has made significant clinical impact, providing a method of visualizing coronary plaques, optimizing percutaneous coronary intervention, and monitoring treatment results. Achieving cellular resolution in cardiovascular optical coherence tomography (OCT) adds even greater utility; thin-cap fibroatheromas (TCFA) that include microcalcifications, cholesterol crystals, and macrophages are hypothesized to correlate with rupture potential, yet are too small to be imaged by conventional OCT. In this review, we survey new developments in the optical technology that may contribute to the advancement of IVOCT into the microscopic domain, including new light sources and optical configurations. We also describe recent progress in micro-OCT (μOCT), a high-resolution OCT implementation developed in our laboratory that utilizes many of these advances to achieve 1-μm resolution.

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Titel: Toward Clinical μOCT—A Review of Resolution-Enhancing Technical Advances
Autoren:: Kengyeh K. Chu
Giovanni J. Ughi
Linbo Liu
Guillermo J. Tearney
Publikationsdatum: 01.12.2014
DOI: https://doi.org/10.1007/s12410-014-9308-7
Verlag: Springer US
Zeitschrift: Current Cardiovascular Imaging Reports
Ausgabe 12/2014
Print ISSN: 1941-9066
Elektronische ISSN: 1941-9074

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