Background
Uni-dimensional scale |
Visual analogue scale (VAS), numerical rating scale (NRS), and verbal rating scale (VRS) |
Multi-dimensional scales |
5D itch scale, four-item questionnaire, itch severity scale, pruritus grading system |
Measurement of scratching episodes Measurement of limb movements |
Imaging of brain activity |
Measurement of itch threshold |
Scales assessing the psychosocial condition of the patient related to itch ItchQoL, Dermatology Life Quality Index and Beck’s Depression Inventory |
Methods
Statistical analysis
Results
Characteristics |
N = 409 | |
---|---|---|
Age (year) | 63 | ±13 |
Male | 215 | 52.6 |
Causes of kidney disease | ||
Diabetes | 186 | 45.0 |
Chronic glomerulonephritis | 103 | 25.2 |
Hypertension | 78 | 18.6 |
Others | 42 | 10.3 |
Pruritus scale | ||
Numerical rating scale | 3.4 | ±3.0 |
5-D itch scale | 10.9 | ±4.8 |
Calcium (mg/dl) | 9.3 | ±0.9 |
Phosphorus (mg/dl) | 5.6 | ±1.5 |
iPTH (pg/ml) | 111.1 | 448.9 |
Kt/V | 1.3 | ±0.3 |
NRS categories | 5-D itch scale | |||
---|---|---|---|---|
n | Mean ± SD | Min | Max | |
No pruritus (0) | 100 | 6.4 ± 1.5 | 5 | 9 |
Mild (1–3) | 133 | 9.6 ± 2.2 | 5 | 17 |
Moderate (4–6) | 107 | 13.1 ± 3.2 | 7 | 21 |
Severe (7–8) | 39 | 15.7 ± 4.4 | 9 | 25 |
Very severe (≥9) | 30 | 19.5 ± 4.4 | 5 | 25 |
n (%) | Numerical rating scale | |||||
---|---|---|---|---|---|---|
No pruritus (0)
n = 100 | Mild (1–3)
n = 133 | Moderate (4–6)
n = 106 | Severe (7–8)
n = 39 | Very severe (≥9)
n = 30 | ||
5-D itch scale | ≤8 n = 141 | 99 (70.2) | 36 (25.5) | 5 (3.5) | 1 (0.7) | 0 (0) |
9–11 n = 110 | 1 (0.9) | 72 (65.5) | 27 (24.5) | 7 (6.4) | 3 (2.7) | |
12–17 n = 109 | 0 (0) | 25 (22.9) | 65 (59.6) | 15 (13.8) | 4 (3.7) | |
18–21 n = 32 | 0 (0) | 0 (0) | 9 (28.1) | 13 (40.6) | 10 (31.3) | |
≥22 n = 16 | 0 (0) | 0 (0) | 0 (0) | 3 (18.8) | 13 (81.2) |