Erschienen in:
28.04.2018 | Overactive Bladder (U Lee and S Adelstein, Section Editors)
Trends in Utilization of Third-Line Therapies for Non-neurogenic Overactive Bladder: Sacral Neuromodulation, Peripheral Tibial Nerve Stimulation, and Intradetrusor OnabotulinumtoxinA
verfasst von:
Anna C. Kirby, Elizabeth S. Kellogg
Erschienen in:
Current Bladder Dysfunction Reports
|
Ausgabe 2/2018
Einloggen, um Zugang zu erhalten
Abstract
Purpose of Review
To report on current and emerging trends in the use of third-line therapies for non-neurogenic overactive bladder (OAB).
Recent findings
The use of third-line therapies for OAB has been steadily increasing, but it appears that only a small percentage of OAB patients receive them. Recent research has found an increased risk of dementia associated with cumulative use of anticholinergic medications, including OAB antimuscarinic medications. Cost-effective analyses suggest that these third-line therapies may be worth considering prior to medications.
Summary
Research and efforts to improve adherence to current OAB guidelines are needed to increase their use by patients with refractory OAB. Whether or not the therapies we presently consider third line should actually be second line for some of our patients remains to be determined.