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01.01.2008 | Original Paper

Two new lignan glucosides from the fruit of Vitex cannabifolia

verfasst von: Toru Yamasaki, Tetsuro Kawabata, Chikako Masuoka, Junei Kinjo, Tsuyoshi Ikeda, Toshihiro Nohara, Masateru Ono

Erschienen in: Journal of Natural Medicines | Ausgabe 1/2008

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Abstract

Two new phenyldihydronaphthalene-type lignan glucosides, vitecannasides A (1) and B (2) were isolated from the fruit of Vitex cannabifolia Sieb. et. Zucc. (Verbenaceae) along with the six known lignan derivatives (3–8), four known iridoid glucosides (9–12), three known flavonoids (13–15), and one known phenylbutanone glucoside (16). Their chemical structures were determined on the basis of spectroscopic data as well as chemical evidence. The scavenging effect of 1, 2, and 11–16 on the stable free radical 1,1-diphenyl-2-picrylhydrazyl was examined. Compounds 1, 2, 14, and 15 exhibited stronger activity than that of l-cysteine. Especially, 14 and 15 showed more potent activity than that of α-tocopherol.

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Titel: Two new lignan glucosides from the fruit of Vitex cannabifolia
verfasst von: Toru Yamasaki
Tetsuro Kawabata
Chikako Masuoka
Junei Kinjo
Tsuyoshi Ikeda
Toshihiro Nohara
Masateru Ono
Publikationsdatum: 01.01.2008
Verlag: Springer-Verlag
Erschienen in: Journal of Natural Medicines / Ausgabe 1/2008
Print ISSN: 1340-3443
Elektronische ISSN: 1861-0293
DOI: https://doi.org/10.1007/s11418-007-0184-1

Springer Medizin

Abstract

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