Background
Construction and content
Data collection
Data incorporation
Summary of the Data
Web implementation and Database design
Utility
Common features
T2D gene information features
SNP association result features
Analysis of T2DGADB data
Discussion
T2DGADB | T2D-DB1
| Hindorff et al.2
| Johnson et al.3
| T1Dbase4
| |
---|---|---|---|---|---|
T2D Candidate genes | 530 | 330 | 50 | 476 | |
Unique genes | 421 | NS | 23 | 380 | |
T2D Candidate SNP Markers | 2108 | NS | 76 | 6076 | |
Unique Markers | 1874 | NS | 28 | 5841 | |
T2DM publication | 701 | 8963 | 23 | 12 | |
coverage year | 2000 ~ 2009. 10 | ~ 2009. 1 | 2005 ~ 2010. 10 | 2002. 12 ~ 2008. 2 | ~ 2010. 10 |
data coverage | T2D candidate gene approach, GWAS | T2D candidate gene approach, GWAS | GWAS (disease/trait) | GWAS (disease/trait) | T1D candidate gene approach, GWAS |
association data format | text, graph | NA | text | text | text |
feature | summary of T2D related genetic association study results(sample size, gene, SNP, MAF, p-value, OR, covariant, etc.) | summary of molecular factors using public databases (EST, Transcripts, Unigene, Homologene, GO, Pathways, Tissue Specific Expression, Protein-Protein interactor, Riskfactors, Complications) | summary of GWAS data (Disease, sample size, gene, SNP, MAF, p-value, OR, platform, CNV, etc.) | summary of GWAS data (Disease, sample size, gene, SNP, MAF, p-value, OR, platform, CNV, etc.) | summary of T1D related molecular factors (T1D susceptibility regions, Genetic data, Microarray data, functional annotation, Network & Pathway), analysis tools |