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Journal of Mammary Gland Biology and Neoplasia

Erschienen in:

21.01.2021 | Preface

Unraveling the Breast: Advances in Mammary Biology and Cancer Methods

verfasst von: Teresa Monkkonen, Gunnhildur Ásta Traustadóttir, Zuzana Koledova

Erschienen in: Journal of Mammary Gland Biology and Neoplasia | Ausgabe 4/2020

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Abstract

The field of mammary gland biology and breast cancer research encompasses a wide range of topics and scientific questions, which span domains of molecular, cell and developmental biology, cancer research, and veterinary and human medicine, with interdisciplinary overlaps to non-biological domains. Accordingly, mammary gland and breast cancer researchers employ a wide range of molecular biology methods, in vitro techniques, in vivo approaches as well as in silico analyses. The list of techniques is ever-expanding; together with the refinement of established, staple techniques in the field, new technologies keep emerging thanks to technological advances and scientific creativity. This issue of the Journal of Mammary Gland Biology and Neoplasia represents a compilation of original articles and reviews focused on methods used in mammary gland biology and breast cancer research.

Schultz-Pernice I, Engelbrecht LK, Petricca S, Scheel CH, Twigger A-J. Morphological Analysis of Human Milk Membrane Enclosed Structures Reveals Diverse Cells and Cell-like Milk Fat Globules. J Mammary Gland Biol Neoplasia. 2020. https://doi.org/10.1007/s10911-020-09472-1.CrossRef

Martin Carli JF, Trahan GD, Jones KL, et al. Single Cell RNA Sequencing of Human Milk-Derived Cells Reveals Sub-Populations of Mammary Epithelial Cells with Molecular Signatures of Progenitor and Mature States: a Novel, Non-invasive Framework for Investigating Human Lactation Physiology. J Mammary Gland Biol Neoplasia. 2020. https://doi.org/10.1007/s10911-020-09466-z.CrossRefPubMed

Twigger A-J, Engelbrecht LK, Bach K, Schultz-Pernice I, Petricca S, Scheel CH, et al. Transcriptional changes in the mammary gland during lactation revealed by single cell sequencing of cells from human milk. bioRxiv. 2020;2020.11.06.371443.

Stewart TA, Davis FM. Got Milk? Identifying and Characterizing Lactation Defects in Genetically-Engineered Mouse Models. J Mammary Gland Biol Neoplasia. 2020. https://doi.org/10.1007/s10911-020-09467-y.CrossRefPubMed

Feigman MJ, Moss MA, Chen C, Cyrill SL, Ciccone MF, Trousdell MC, et al. Pregnancy reprograms the epigenome of mammary epithelial cells and blocks the development of premalignant lesions. Nat Commun. 2020;11:2649.CrossRef

Ciccone MF, Trousdell MC, dos Santos CO. Characterization of Organoid Cultures to Study the Effects of Pregnancy Hormones on the Epigenome and Transcriptional Output of Mammary Epithelial Cells. J Mammary Gland Biol Neoplasia. 2020. https://doi.org/10.1007/s10911-020-09465-0.CrossRefPubMed

Sumbal J, Chiche A, Charifou E, Koledova Z, Li H. Primary Mammary Organoid Model of Lactation and Involution. Front Cell Dev Biol [Internet]. Frontiers; 2020 [cited 2020 Apr 5];8. Available from: https://www.frontiersin.org/articles/https://doi.org/10.3389/fcell.2020.00068/full.

Sumbal J, Budkova Z, Traustadóttir GÁ, et al. Mammary Organoids and 3D Cell Cultures: Old Dogs with New Tricks. J Mammary Gland Biol Neoplasia. 2020. https://doi.org/10.1007/s10911-020-09468-x.CrossRefPubMed

Wrenn ED, Moore BM, Greenwood E, et al. Optimal, Large-Scale Propagation of Mouse Mammary Tumor Organoids. J Mammary Gland Biol Neoplasia. 2020. https://doi.org/10.1007/s10911-020-09464-1.CrossRefPubMedPubMedCentral

10.

Lan Q, Mikkola ML. Protocol: Adeno-Associated Virus-Mediated Gene Transfer in Ex Vivo Cultured Embryonic Mammary Gland. J Mammary Gland Biol Neoplasia. 2020. https://doi.org/10.1007/s10911-020-09461-4.CrossRefPubMed

11.

Bu W, Li Y. Intraductal Injection of Lentivirus Vectors for Stably Introducing Genes into Rat Mammary Epithelial Cells in Vivo. J Mammary Gland Biol Neoplasia. 2020. https://doi.org/10.1007/s10911-020-09469-w.CrossRefPubMed

12.

Hillers-Ziemer LE, Arendt LM. Weighing the Risk: effects of Obesity on the Mammary Gland and Breast Cancer Risk. J Mammary Gland Biol Neoplasia. 2020;25:115–31.CrossRef

13.

Giles ED, Wellberg EA. Preclinical Models to Study Obesity and Breast Cancer in Females: Considerations, Caveats, and Tools. J Mammary Gland Biol Neoplasia. 2020. https://doi.org/10.1007/s10911-020-09463-2.CrossRefPubMed

14.

Wortzel I, Dror S, Kenific CM, Lyden D. Exosome-Mediated Metastasis: Communication from a Distance. Dev Cell. 2019;49:347–60.CrossRef

15.

Pelissier Vatter FA, Lucotti S, Zhang H. Recent Advances in Experimental Models of Breast Cancer Exosome Secretion, Characterization and Function. J Mammary Gland Biol Neoplasia. 2020. https://doi.org/10.1007/s10911-020-09473-0.CrossRefPubMed

16.

Turashvili G, Brogi E. Tumor Heterogeneity in Breast Cancer. Front Med (Lausanne) [Internet]. 2017 [cited 2020 Dec 7];4. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727049/

17.

Baek M, Chang JT, Echeverria GV. Methodological Advancements for Investigating Intra-tumoral Heterogeneity in Breast Cancer at the Bench and Bedside. J Mammary Gland Biol Neoplasia. 2020. https://doi.org/10.1007/s10911-020-09470-3.CrossRefPubMed

18.

Swann JB, Smyth MJ. Immune surveillance of tumors. J Clin Invest. 2007;117:1137–46.CrossRef

19.

Mori H, Bolen J, Schuetter L, Massion P, Hoyt CC, VandenBerg S, Esserman L, Borowsky AD, Campbell MJ. Characterizing the tumor immune microenvironment with tyramide based multiplex immunofluorescence. J Mammary Gland Biol Neoplasia. 2021.

20.

van de Grift YBC, Heijmans N, van Amerongen R. How to Use Online Tools to Generate New Hypotheses for Mammary Gland Biology Research: A Case Study for Wnt7b. J Mammary Gland Biol Neoplasia. 2020. https://doi.org/10.1007/s10911-020-09474-z.CrossRef

Titel: Unraveling the Breast: Advances in Mammary Biology and Cancer Methods
verfasst von: Teresa Monkkonen
Gunnhildur Ásta Traustadóttir
Zuzana Koledova
Publikationsdatum: 21.01.2021
Verlag: Springer US
Erschienen in: Journal of Mammary Gland Biology and Neoplasia / Ausgabe 4/2020
Print ISSN: 1083-3021
Elektronische ISSN: 1573-7039
DOI: https://doi.org/10.1007/s10911-020-09476-x

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Unraveling the Breast: Advances in Mammary Biology and Cancer Methods

Abstract

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Weitere Artikel der Ausgabe 4/2020

Optimal, Large-Scale Propagation of Mouse Mammary Tumor Organoids

Mammary Organoids and 3D Cell Cultures: Old Dogs with New Tricks

Preclinical Models to Study Obesity and Breast Cancer in Females: Considerations, Caveats, and Tools

Protocol: Adeno-Associated Virus-Mediated Gene Transfer in Ex Vivo Cultured Embryonic Mammary Gland

Methodological Advancements for Investigating Intra-tumoral Heterogeneity in Breast Cancer at the Bench and Bedside

Characterization of Organoid Cultures to Study the Effects of Pregnancy Hormones on the Epigenome and Transcriptional Output of Mammary Epithelial Cells

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Adjuvante Immuntherapie verlängert Leben bei RCC

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