Erschienen in:
01.07.2015 | Case Report
Uterine Tumors Resembling Ovarian Sex Cord Tumor in Postmenopausal Woman
verfasst von:
Jung Mi Byun, Ki Tae Kim, Hye Kyoung Yoon, Dae Hoon Jeong, Young Nam Kim, Kyung Bok Lee, Moon Su Sung
Erschienen in:
The Journal of Obstetrics and Gynecology of India
|
Ausgabe 4/2015
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Excerpt
Uterine tumors resembling ovarian sex cord tumors (UTROSCTs) are a rare group of stromal neoplasms containing prominent sex cord-like elements. Since they were first described in 1945 by Morehead and Bowman [
1], no more than 100 such tumors have been reported [
2]. In a report by Clement and Scully [
3], these neoplasms were divided into 2 groups on the basis of clinical and histologic patterns. The first group (group I) included endometrial stromal tumors with less than 50 % sex cord-like elements, and the second group (group II) included UTROSCTs exhibiting sex cord-like differentiation of more than 50 %. In the latest, according to the World Health Organization classification of uterine neoplasms, UTROSCTs were placed in a miscellaneous category of tumors of the uterine corpus because of their different morphology and benign clinical behaviors [
4]. More recently, UTROSCTs have been suggested to be unusual neoplasms of uncertain malignancy with polyphenotypic immunohistochemical expression, characterized by positivity for sex cord, epithelial, and myoid markers [
5,
6]. These tumors usually occur in premenopausal or menopausal women. Most patients have symptoms such as abnormal vaginal bleeding, abdominal pain, and enlarged uterus or a palpable uterine mass on physical examination [
7]. In most cases, UTROSCT is diagnosed incidentally after hysterectomy for a clinical diagnosis of an endometrial polyp [
8,
9] or sometimes leiomyoma [
10]. …