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01.12.2017 | Research | Ausgabe 1/2017 Open Access

AIDS Research and Therapy 1/2017

Validity assessment of the PROMIS fatigue domain among people living with HIV

Zeitschrift:
AIDS Research and Therapy > Ausgabe 1/2017
Autoren:
L. E. Gibbons, R. Fredericksen, D. S. Batey, L. Dant, T. C. Edwards, K. H. Mayer, W. C. Mathews, L. S. Morales, M. J. Mugavero, F. M. Yang, E. Paez, M. M. Kitahata, D. L. Patrick, H. M. Crane, P. K. Crane, for the Centers for AIDS Research Network of Integrated Clinical Systems (CNICS)
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1186/​s12981-017-0146-y) contains supplementary material, which is available to authorized users.

Abstract

Purpose

To evaluate psychometric characteristics and cross-sectional and longitudinal validity of the 7-item PROMIS® Fatigue Short Form and additional fatigue items among people living with HIV (PLWH) in a nationally distributed network of clinics collecting patient reported data at the time of routine clinical care.

Methods

Cross-sectional and longitudinal fatigue data were collected from September 2012 through April 2013 across clinics participating in the Centers for AIDS Research Network of Integrated Clinical Systems (CNICS). We analyzed data regarding psychometric characteristics including simulated computerized adaptive testing and differential item functioning, and regarding associations with clinical characteristics.

Results

We analyzed data from 1597 PLWH. Fatigue was common in this cohort. Scores from the PROMIS® Fatigue Short Form and from the item bank had acceptable psychometric characteristics and strong evidence for validity, but neither performed better than shorter instruments already integrated in CNICS.

Conclusions

The PROMIS® Fatigue Item Bank is a valid approach to measuring fatigue in clinical care settings among PLWH, but in our analyses did not perform better than instruments associated with less respondent burden.
Zusatzmaterial
Additional file 1. Loadings and thresholds for Mplus based on the PROMIS item bank parameters, and using 2 anchor items and 5 freely estimated items.
Additional file 2. Difference in scores between the PROMIS-7a scored using PROMIS item parameters and a score where 2 items are fixed to the PROMIS item parameters and the other 5 are freely estimated. The horizontal line at zero represents no difference, and the upper and lower curves represent the standard error of measurement. All differences are within the standard error of measurement curves.
Literatur
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