Erschienen in:
01.12.2012 | Original Article
Vitamin D status in women with pelvic floor disorder symptoms
verfasst von:
Candace Y. Parker-Autry, Alayne D. Markland, Alicia C. Ballard, Deidra Downs-Gunn, Holly E. Richter
Erschienen in:
International Urogynecology Journal
|
Ausgabe 12/2012
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Abstract
Introduction and hypothesis
Our aim was to characterize the relationship between 25-hydroxyvitamin D [25(OH)D] status with pelvic floor symptom distress and impact on quality of life.
Methods
A retrospective chart review was performed in women with a 25(OH)D level drawn within 1 year of their gynecology/urogynecology visit. Validated questionnaires including the Colorectal–Anal Distress Inventory (CRADI)-8 and Incontinence Impact Questionnaire (IIQ-7) were used. Multivariate analyses characterized pelvic floor disorder (PFD) symptom differences among women by vitamin D status.
Results
We studied 394 women. Mean ± standard deviation (SD) 25(OH)D levels were higher in women without than with
PFD symptoms (35.0 ± 14.1 and 29.3 ± 11.5 ng/ml, respectively (p < 0.001)]. The prevalence of vitamin D insufficiency was 51% (136/268). CRADI-8 and IIQ-7 scores were higher among women with vitamin D insufficiency (p = 0.03 and p = 0.001, respectively). Higher IIQ-7 scores were independently associated with vitamin D insufficiency (p < 0.001).
Conclusions
Insufficient vitamin D is associated with increased colorectal symptom distress and greater impact of urinary incontinence on quality of life.