Erschienen in:
30.10.2022 | Editorial Perspective
We Asked the Experts: Surgical Approach to Low Rectal Cancer—Where Innovation Happens
verfasst von:
Fabian Grass, David W. Larson
Erschienen in:
World Journal of Surgery
|
Ausgabe 4/2023
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Excerpt
Over the last decade, we observed a paradigm shift in the treatment of locally advanced rectal cancer (LARC) with an increasing trend towards non-surgical management, yielding complete clinical response rates of up to 30% after total neoadjuvant chemotherapy or intensified chemoradiation. In addition, some protocols promote local excision and nonsurgical treatment to increase the chances of avoiding radical surgery. In contrast, non-responders to organ-preserving strategies continue to require total mesorectal excision (TME) according to the highest quality standards. …