What a paediatrician should know about congenital clubfoot

Congenital clubfoot is a malformation characterized by a torsion of the longitudinal axis of the foot, secondary to a malalignment of the calcaneo-talar-navicular complex. The foot’s sole is rotated medially and this leads the child to walk on the foot sides (Fig. 1). We can detect four different anomalies; CAVE is a mnemonic tip to remember them all (Fig. 2):

There are two main types of congenital clubfoot: idiopathic (80% of cases) and secondary clubfoot (20% of cases). The idiopathic congenital clubfoot is a multifactorial condition that includes environmental, vascular, positional, and genetic factors. Clubfoot has a tendency to segregate in families: the risk of developing congenital clubfoot is 25% when a first-degree relative is affected. Several studies and observations suggest the existence of different genes and inheritance patterns involved [3]. On the other hand, up to 20% of cases of congenital clubfoot is associated to other anomalies (e.g., myelomeningocele) and could be secondary to a specific genetic condition such as Moebius syndrome, neurofibromatosis and multiple congenital arthrogryposes [4]. The congenital clubfoot could also show more complex anatomic features that typically present a shorter and more rigid foot, in which there is a marked curvature of the midfoot (metatarsal equinism) with deep skin folds. In these cases we talk about an “atypical clubfoot” [5]. Clinical features of clubfoot may already emerge in prenatal diagnostics, but its ultrasonographic diagnosis appears more likely between the 18th and the 24th week of pregnancy [6].

The foot needs to be evaluated in their complexity: general morphology, presence of skin folds, muscular and tendon malleability and flexibility of the deformation. Flexibility is the most relevant element that influences the prognosis: the more malleable and easy to move the foot, the better the prognosis. There are several classification systems of the clubfoot, for example Manes-Costa’s classification, Pirani’s score (Fig. 3) or Dimeglio classification. These scores are valid prognostic tools and can be used in the follow-up process. A high score at presentation may indicate that a longer and more complex treatment will be required. Whenever a congenital clubfoot is detected, a complete examination is mandatory to rule out other neuro-musculoskeletal problems, such as signs of occult spinal dysraphism, developmental dysplasia of the hip (DDH) or congenital torticollis.

It is essential to differentiate clubfoot from two other disorders: postural equino-varus foot and metatarsus adductus. The postural equino-varus is a functional malposition of the foot caused by the deformed position that the fetus used to hold in the maternal womb. In this case, there may be some degrees of forefoot adduction, but it will be flexible at the manipulation, and there will be no Achilles tendon contracture. Generally, the postural equino-varus resolves spontaneously; nevertheless, it is good practice to monitor the progression (in premature newborn, a clubfoot can sometimes hide behind a postural equino-varus) [7]. The adductus metatarsus is another common deformity characterized by an adducted forefoot with a curvature of the lateral edge of the foot, but without the other features of clubfoot. Also, this disorder is secondary to the intrauterine postural modeling of the feet and generally resolves spontaneously (casting may be necessary if the deformity is rigid).

Over the decades the surgical treatment of congenital clubfoot has mostly been abandoned, as it was associated with complications, with the final result of a foot that would hardly reached full functionality, due to retractions and scars, secondary to the surgery itself. Although some complex and atypical clubfeet still need surgical treatments at first [7], the available evidence has definitively confirmed the effectiveness of the Ponseti non-invasive method [1, 8, 9]. It consists of gentle manipulations of the foot followed by the application of plaster casts, which are kept in place for 5-7 days, during which muscles and ligaments adapt to the new position. At the end of the 5-7 days period, the cast is removed, the foot (which would become softer and more prone to be moulded) is revaluated and progressively manipulated to maintain, through the application of a new cast, a new position [2, 8]. The procedure is repeated until normal foot alignment is achieved (on average, about five to six plaster casts are required). Percutaneous Achille’s tenotomy (Fig. 4) could be required if equinus deformity persists at the end of the casting phase. The procedure takes about 5 min and consists of a millimetric posterior skin incision through which the tendon section is achieved. After the tenotomy, plaster is applied to allow the tendon to heal in elongation for about 20 days. In order to maintain the correct position of the foot,it is necessary to wear, an orthopedic brace until 5 years of age. The brace must be worn for 23 h a day for the first 3 months. Over time, the child may gradually decrease the use of the brace during the day:: after the first months, it is necessary to wear the cast for at least 18–19 h with a gradual reduction in the use of 1 h per month up to a maximum of 12 h without the brace. When the patient begins to walk independently, the brace is usually only held overnight until the age of five.. Compliance with the splinting programme is crucial to prevent recurrences [10], and the general paediatrician has a critical role in supporting the family during the brace-phase.

To conclude, the treatment of an “atypical clubfoot” is more challenging and difficult and often requires a higher number of plaster casts.

Radiological diagnostic evaluations, such as foot X-rays or ultrasounds, are usually not necessary in addition to the clinical assessment. In the case of very complex clubfoot, it could be reasonable to evaluate the possibility of an underlying process or other associated malformation. A co-existent hip dysplasia, myogenic torticollis, or other orthopedic conditions should always be ruled out. The paediatrician also has to evaluate the child to exclude a systemic condition (such as a neuromuscular disease or a syndromic illness – see Table 1). Paediatricians are also in charge of preparing the family for the therapeutic process. Reassurance and providing a direct link to an experienced centre are the first steps. Operational timeliness is essential in terms of outcomes so the newborn needs to be referred to the specialist as soon as possible, e.g., in the very first days of life. The relapses of the clubfoot are not uncommon (about 5–10%), either with conservative and surgical methods. Consequently, paediatricians should play a relevant role in supporting the family and monitoring compliance with the constant use of the orthopedic brace, which represents the main factor in preventing the recurrence of malformation.