Erschienen in:
01.08.2004 | Letter
Yellow nail syndrome in rheumatoid arthritis: a drug-induced disease?
verfasst von:
Eve David-Vaudey, Benedicte Jamard, Chistophe Hermant, Alain Cantagrel
Erschienen in:
Clinical Rheumatology
|
Ausgabe 4/2004
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Excerpt
Yellow nail syndrome (YNS) is characterized by a chronic nail disorder (slow growth of nails and yellowish discoloration), lymphedema and respiratory symptoms [
1]. Its pathogenesis is poorly understood and probably heterogeneous, because YNS has been associated with various conditions, including autoimmune diseases. Rheumatoid arthritis (RA) is the most frequent autoimmune disease leading to YNS, and two types of YNS can be defined: spontaneous or therapy related. Therapy-related YNS in RA has been essentially described with thiol drugs (
d-penicillamine). The patient described here is the second case reported in the literature with tiopronine (thiol analog)-induced YNS. …