Erschienen in:
Open Access
01.12.2012 | Poster presentation
A novel role for monosodium urate monohydrate crystals and gouty synovial fluids in monocyte migration in gout
verfasst von:
M Asif Amin, Qiang Shu, Jonathon W Vargo, Jeffrey H Ruth, Takeo Isozaki, Solhee Lee, Alisa E Koch
Erschienen in:
Arthritis Research & Therapy
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Sonderheft 1/2012
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Excerpt
Gout is characterized by intra-articular deposition of monosodium urate monohydrate (MSU) crystals. The role of neutrophil influx in acute gouty arthritis is well established, while the contribution of monocytes (MNs) and their secreted inflammatory mediators is not. Here we demonstrate the role of MSU in MN migration. …