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Erschienen in:
01.11.2014 | Retinal Disorders
A novel spectral-domain optical coherence tomography model to estimate changes in vitreomacular traction syndrome
Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology | Ausgabe 11/2014
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Purpose
To analyze the course of eyes with vitreomacular traction (VMT), and to find by optical coherence tomography (OCT) possible correlations between vitreomacular interface area changes and the chance of spontaneous VMT resolution.
Methods
Retrospective analysis of all consecutive patients presenting with VMT over a 24-month period. We introduced a novel OCT evaluation model to assess the vitreomacular interface area. Central foveal thickness (CFT) and best-corrected visual acuity (BCVA) were also analyzed throughout follow-up.
Results
Twenty-six eyes of 18 symptomatic patients were followed for 12.9 ± 4.8 months. Eyes were subdivided into groups according to their clinical course. Six eyes (23%) had a spontaneous resolution of the VMT (group A), and the interface area before its occurrence (39565 ± 26409 μm2) was smaller than at study entry (99434 ± 38819 μm2; p = 0.03). The interface area did not significantly change throughout follow-up in the group that underwent surgery (group B, 11 eyes) and in the group that remained overall stable (group C, 9 eyes). At baseline, the interface area was smaller in group A compared to groups with non-resolved VMT (mean values of group B and C together) (785095 ± 920721 μm2; p = 0.002). CFT and BCVA did not significantly change in any of the studied groups. Vitreomacular interface area of 101002 μm2 was identified as the threshold value separating the spontaneous VMT resolution group from the group with non-resolved VMT (p < 0.001).
Conclusions
The more the vitreomacular interface area reduced over time, the higher was the chance of spontaneous VMT resolution. An area below 101002 μm2 was the threshold value indicating a higher chance of spontaneous release of VMT.