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01.04.2009 | Review Paper

A review on the management of epilepsy associated with hypothalamic hamartomas

verfasst von: James L. Frazier, C. Rory Goodwin, Edward S. Ahn, George I. Jallo

Erschienen in: Child's Nervous System | Ausgabe 4/2009

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Abstract

Introduction

Hypothalamic hamartomas are rare congenital malformations located in the region of the tuber cinereum and third ventricle. Patients may be asymptomatic, but the usual presentation is gelastic seizures, precocious puberty, and/or developmental delay.

Clinical presentation

Without surgical intervention, the gelastic seizures, which are typically present in childhood, may progress to other seizure types, including generalized epilepsy, and are generally refractory to antiepileptic drugs.

Summary

This review will discuss the clinical and electrophysiologic aspects of these lesions, as well as treatment options, including surgery, endoscopy, and radiosurgery.

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Titel: A review on the management of epilepsy associated with hypothalamic hamartomas
verfasst von: James L. Frazier
C. Rory Goodwin
Edward S. Ahn
George I. Jallo
Publikationsdatum: 01.04.2009
Verlag: Springer-Verlag
Erschienen in: Child's Nervous System / Ausgabe 4/2009
Print ISSN: 0256-7040
Elektronische ISSN: 1433-0350
DOI: https://doi.org/10.1007/s00381-008-0798-y

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