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Erschienen in: International Journal of Diabetes in Developing Countries 1/2017

03.05.2015 | Original Article

A web-based interactive lifestyle modification program improves lipid profile and serum adiponectin concentrations in patients with metabolic syndrome: the “Red Ruby” study

verfasst von: Mahdieh Abbasalizad Farhangi, Leila Jahangiry, Mir-Mousa Mirinazhad, Davoud Shojaeezade, Ali Montazeri, Alireza Yaghoubi

Erschienen in: International Journal of Diabetes in Developing Countries | Ausgabe 1/2017

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Abstract

The effectiveness of internet-based programs in prevention and treatment of metabolic syndrome has not been fully explored. In the present study, we investigate the effect of a 6-month web-based interactive lifestyle modification program on anthropometric variables and biochemical risk factors of cardiovascular disease. The study had been carried out among 160 patients with metabolic syndrome (intervention, n = 80; control, n = 80). The primary outcomes were change in anthropometric variables, fasting serum glucose (FSG), lipid profile, insulin sensitivity, and serum adiponectin concentrations in intervention and control groups. Significant reductions in anthropometric variables and serum lipids were observed in both intervention and control groups; however, reduction in waist-to-hip ratio (WHR), total cholesterol (TC), and low-density lipoprotein cholesterol (LDL-C) was only significant in intervention group (P < 0.05). Reduction in anthropometric variables and serum triglyceride, systolic and diastolic blood pressure, and liver enzymes were significant in intervention and control groups (P < 0.05) but in women decrease in FSG, TC, and LDL-C were only significant in intervention group (P < 0.05). The present study showed that a web-based intervention was effective in weight loss and improving cardio-metabolic factors in patients with metabolic syndrome after a 6-month intervention.
Literatur
1.
Zurück zum Zitat Aggarwal A, Aggarwal S, Sharma V. Cardiovascular risk factors in young patients of coronary artery disease: differences over a decade. J Cardiovasc Thorac Res. 2014;6(3):169–73.CrossRefPubMedPubMedCentral Aggarwal A, Aggarwal S, Sharma V. Cardiovascular risk factors in young patients of coronary artery disease: differences over a decade. J Cardiovasc Thorac Res. 2014;6(3):169–73.CrossRefPubMedPubMedCentral
2.
Zurück zum Zitat Saghafi-Asl M, Pirouzpanah S, Ebrahimi-Mameghani M, Asghari-Jafarabadi M, Aliashrafi S, Sadein B. Lipid profile in relation to anthropometric indices and insulin resistance in overweight women with polycystic ovary syndrome. HPP. 2013;3(2):206–16.PubMedPubMedCentral Saghafi-Asl M, Pirouzpanah S, Ebrahimi-Mameghani M, Asghari-Jafarabadi M, Aliashrafi S, Sadein B. Lipid profile in relation to anthropometric indices and insulin resistance in overweight women with polycystic ovary syndrome. HPP. 2013;3(2):206–16.PubMedPubMedCentral
3.
Zurück zum Zitat Malik S, Wong ND, Franklin SF, Kamath TV, L’Italien GJ, Pio JR, et al. Cardiovascular disease and all causes in United States adults impact of the metabolic syndrome on mortality from coronary heart disease. Circulation. 2004;110:1245–50.CrossRefPubMed Malik S, Wong ND, Franklin SF, Kamath TV, L’Italien GJ, Pio JR, et al. Cardiovascular disease and all causes in United States adults impact of the metabolic syndrome on mortality from coronary heart disease. Circulation. 2004;110:1245–50.CrossRefPubMed
4.
Zurück zum Zitat Lakka HM, Laaksonen DE, Lakka TA, Niskanen LK, Kumpusalo E, Tuomilehto J, et al. The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. JAMA. 2002;288(21):2709–16.CrossRefPubMed Lakka HM, Laaksonen DE, Lakka TA, Niskanen LK, Kumpusalo E, Tuomilehto J, et al. The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. JAMA. 2002;288(21):2709–16.CrossRefPubMed
5.
Zurück zum Zitat Mottillo S, Filion KB, Genest J, Joseph L, Pilote L, Poirier P, et al. The metabolic syndrome and cardiovascular risk. A systematic review and meta-analysis. J Am Coll Cardiol. 2010;56(14):1113–32.CrossRefPubMed Mottillo S, Filion KB, Genest J, Joseph L, Pilote L, Poirier P, et al. The metabolic syndrome and cardiovascular risk. A systematic review and meta-analysis. J Am Coll Cardiol. 2010;56(14):1113–32.CrossRefPubMed
6.
Zurück zum Zitat Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults. JAMA. 2002;287(3):356–9.CrossRefPubMed Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults. JAMA. 2002;287(3):356–9.CrossRefPubMed
7.
Zurück zum Zitat Azizi F, Salehi P, Etemadi A, Zahedi-Asl S. Prevalence of metabolic syndrome in an urban population: Tehran Lipid and Glucose Study. Diab Res Clin Pract. 2003;61(1):29–37.CrossRef Azizi F, Salehi P, Etemadi A, Zahedi-Asl S. Prevalence of metabolic syndrome in an urban population: Tehran Lipid and Glucose Study. Diab Res Clin Pract. 2003;61(1):29–37.CrossRef
8.
Zurück zum Zitat Aggarwal A, Aggarwal S, Sarkar PG, Sharma V. Predisposing factors to premature coronary artery disease in young (age ≤ 45 years) smokers: a single center retrospective case control study from India. J Cardiovasc Thorac Res. 2014;6(1):15–9.PubMedPubMedCentral Aggarwal A, Aggarwal S, Sarkar PG, Sharma V. Predisposing factors to premature coronary artery disease in young (age ≤ 45 years) smokers: a single center retrospective case control study from India. J Cardiovasc Thorac Res. 2014;6(1):15–9.PubMedPubMedCentral
9.
Zurück zum Zitat Esposito K, Marfella R, Ciotola M, Di Palo C, Giugliano F, Giugliano G, et al. Effect of a Mediterranean-style diet on endothelial dysfunction and markers of vascular inflammation in the metabolic syndrome. JAMA. 2004;292(12):1440–6.CrossRefPubMed Esposito K, Marfella R, Ciotola M, Di Palo C, Giugliano F, Giugliano G, et al. Effect of a Mediterranean-style diet on endothelial dysfunction and markers of vascular inflammation in the metabolic syndrome. JAMA. 2004;292(12):1440–6.CrossRefPubMed
10.
Zurück zum Zitat Azadbakht L, Mirmiran P, Esmaillzadeh A, Azizi T, Azizi F. Beneficial effects of a dietary approaches to stop hypertension eating plan (DASH) on features of the metabolic syndrome. Diab Care. 2005;28(12):2823–31.CrossRef Azadbakht L, Mirmiran P, Esmaillzadeh A, Azizi T, Azizi F. Beneficial effects of a dietary approaches to stop hypertension eating plan (DASH) on features of the metabolic syndrome. Diab Care. 2005;28(12):2823–31.CrossRef
11.
12.
Zurück zum Zitat Bond GE, Burr R, Wolf FM, Price M, Mccurry SM, Teri L. The effects of a web-based intervention on the physical outcomes associated with diabetes among adults age 60 and older: a randomized trial. Diab Technol Ther. 2007;9(1):52–9.CrossRef Bond GE, Burr R, Wolf FM, Price M, Mccurry SM, Teri L. The effects of a web-based intervention on the physical outcomes associated with diabetes among adults age 60 and older: a randomized trial. Diab Technol Ther. 2007;9(1):52–9.CrossRef
13.
Zurück zum Zitat Ramadas A, Quek KF, Chan CK, Oldenburg B. Web-based interventions for the management of type 2 diabetes mellitus: a systematic review of recent evidence. Int J Med Inform. 2011;80(6):389–405.CrossRefPubMed Ramadas A, Quek KF, Chan CK, Oldenburg B. Web-based interventions for the management of type 2 diabetes mellitus: a systematic review of recent evidence. Int J Med Inform. 2011;80(6):389–405.CrossRefPubMed
14.
Zurück zum Zitat Wantland DJ, Portillo CJ, Holzemer WL, Slaughter R, Mcghee EM. The effectiveness of web-based vs. non-web-based interventions: a meta-analysis of behavioral change outcomes. J Med Internet Res. 2004;6(4):e 40.CrossRef Wantland DJ, Portillo CJ, Holzemer WL, Slaughter R, Mcghee EM. The effectiveness of web-based vs. non-web-based interventions: a meta-analysis of behavioral change outcomes. J Med Internet Res. 2004;6(4):e 40.CrossRef
15.
Zurück zum Zitat Tate DF, Jackvony EH, Wing RR. Effects of Internet behavioral counseling on weight loss in adults at risk for type 2 diabetes. JAMA. 2003;289(14):1833–6.CrossRefPubMed Tate DF, Jackvony EH, Wing RR. Effects of Internet behavioral counseling on weight loss in adults at risk for type 2 diabetes. JAMA. 2003;289(14):1833–6.CrossRefPubMed
16.
Zurück zum Zitat McKay HG, King D, Eakin EG, Seeley JR, Glasgow RE. The diabetes network Internet-based physical activity intervention: a randomized pilot study. Diab Care. 2001;24(8):1328–34.CrossRef McKay HG, King D, Eakin EG, Seeley JR, Glasgow RE. The diabetes network Internet-based physical activity intervention: a randomized pilot study. Diab Care. 2001;24(8):1328–34.CrossRef
17.
Zurück zum Zitat Christensen H, Griffiths KM, Jorm AF. Delivering interventions for depression by using the Internet: randomized controlled trial. BMJ. 2004;328:265–8.CrossRefPubMedPubMedCentral Christensen H, Griffiths KM, Jorm AF. Delivering interventions for depression by using the Internet: randomized controlled trial. BMJ. 2004;328:265–8.CrossRefPubMedPubMedCentral
18.
Zurück zum Zitat Van-Straten A, Cuijpers P, Smits N. Effectiveness of a web-based self-help intervention for symptoms of depression, anxiety, and stress: randomized controlled trial. J Med Internet Res. 2008;10(1):e7.CrossRefPubMedPubMedCentral Van-Straten A, Cuijpers P, Smits N. Effectiveness of a web-based self-help intervention for symptoms of depression, anxiety, and stress: randomized controlled trial. J Med Internet Res. 2008;10(1):e7.CrossRefPubMedPubMedCentral
19.
Zurück zum Zitat Ybarra ML, Bull SS. Current trends in Internet-and cell phone-based HIV prevention and intervention programs. Curr HIV/AIDS Rep. 2007;4(4):201–7.CrossRefPubMed Ybarra ML, Bull SS. Current trends in Internet-and cell phone-based HIV prevention and intervention programs. Curr HIV/AIDS Rep. 2007;4(4):201–7.CrossRefPubMed
20.
Zurück zum Zitat Jahangiry L, Shojaeizadeh D, Najafi M, Mohammad K, Abbasalizad Farhangi M, Montazeri A. ”Red Ruby”: an interactive web-based intervention for lifestyle modification on metabolic syndrome: a study protocol for a randomized controlled trial. BMC Public Health. 2014;14:748–56.CrossRefPubMedPubMedCentral Jahangiry L, Shojaeizadeh D, Najafi M, Mohammad K, Abbasalizad Farhangi M, Montazeri A. ”Red Ruby”: an interactive web-based intervention for lifestyle modification on metabolic syndrome: a study protocol for a randomized controlled trial. BMC Public Health. 2014;14:748–56.CrossRefPubMedPubMedCentral
21.
Zurück zum Zitat Grundy SM, Hansen B, Smith SC, Cleeman J, Richard A. Clinical management of metabolic syndrome: report of the American Heart Association/National Heart, Lung, and Blood Institute/American Diabetes Association conference on scientific issues related to management. Circulation. 2004;109:551–6.CrossRefPubMed Grundy SM, Hansen B, Smith SC, Cleeman J, Richard A. Clinical management of metabolic syndrome: report of the American Heart Association/National Heart, Lung, and Blood Institute/American Diabetes Association conference on scientific issues related to management. Circulation. 2004;109:551–6.CrossRefPubMed
22.
Zurück zum Zitat Delavari A, Forouzanfar MH, Alikhani S, Kelishadi R. First nationwide study of the prevalence of the metabolic syndrome and optimal cut-off points of waist circumference in the Middle East: the national survey of risk factors for non-communicable disease of Iran. Diab Care. 2009;32:1092–7.CrossRef Delavari A, Forouzanfar MH, Alikhani S, Kelishadi R. First nationwide study of the prevalence of the metabolic syndrome and optimal cut-off points of waist circumference in the Middle East: the national survey of risk factors for non-communicable disease of Iran. Diab Care. 2009;32:1092–7.CrossRef
23.
Zurück zum Zitat Esteghamati A, Abbasi M, Rashidi A, Meysamie A, Khalilzadeh O, Haghazali M, et al. Optimal waist circumference cut-offs for the diagnosis of metabolic syndrome in adults: results from the third national survey of risk factors of non-communicable disease (SuRFNCD). Diab Med. 2009;26:745–6.CrossRef Esteghamati A, Abbasi M, Rashidi A, Meysamie A, Khalilzadeh O, Haghazali M, et al. Optimal waist circumference cut-offs for the diagnosis of metabolic syndrome in adults: results from the third national survey of risk factors of non-communicable disease (SuRFNCD). Diab Med. 2009;26:745–6.CrossRef
24.
Zurück zum Zitat Heart N. Lung, and blood institute, obesity education initiative expert panel. Clinical guidelines in identification, evaluation, and treatment of overweight and obesity in adults: the evidence report. Obes Res. 1998;6(suppl):S51–S210. Heart N. Lung, and blood institute, obesity education initiative expert panel. Clinical guidelines in identification, evaluation, and treatment of overweight and obesity in adults: the evidence report. Obes Res. 1998;6(suppl):S51–S210.
25.
Zurück zum Zitat Hamwi GL. Changing dietary concepts in diabetes mellitus: diagnosis and treatment. New York: American Diabetes Association; 1964. Hamwi GL. Changing dietary concepts in diabetes mellitus: diagnosis and treatment. New York: American Diabetes Association; 1964.
26.
Zurück zum Zitat Alberti KG, Zimmet P, Shaw J. The metabolic syndrome: a new worldwide definition. Diabet Med. 2006;23:469–80.CrossRefPubMed Alberti KG, Zimmet P, Shaw J. The metabolic syndrome: a new worldwide definition. Diabet Med. 2006;23:469–80.CrossRefPubMed
27.
Zurück zum Zitat Farhangi MA, Keshavarz SA, Eshraghian M, Ostadrahimi A, Saboor-Yaraghi AA. White blood cell count in women: relation to inflammatory biomarkers, haematological profiles, visceral adiposity, and other cardiovascular risk factors. J Health Popul Nutr. 2013;31:58–64.CrossRefPubMedPubMedCentral Farhangi MA, Keshavarz SA, Eshraghian M, Ostadrahimi A, Saboor-Yaraghi AA. White blood cell count in women: relation to inflammatory biomarkers, haematological profiles, visceral adiposity, and other cardiovascular risk factors. J Health Popul Nutr. 2013;31:58–64.CrossRefPubMedPubMedCentral
28.
Zurück zum Zitat Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28:412–19.CrossRefPubMed Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28:412–19.CrossRefPubMed
29.
Zurück zum Zitat Viner RM, Segal TY, Lichtarowicz-Krynska E, Hindmarsh P. Prevalence of the insulin resistance syndrome in obesity. Arch Dis Child. 2005;90:10–4.CrossRefPubMedPubMedCentral Viner RM, Segal TY, Lichtarowicz-Krynska E, Hindmarsh P. Prevalence of the insulin resistance syndrome in obesity. Arch Dis Child. 2005;90:10–4.CrossRefPubMedPubMedCentral
30.
Zurück zum Zitat Oh EG, Bang SY, Kim SH, Chu SH, Jeon JY, Im JA, et al. Effects of a 6-month lifestyle modification intervention on the cardiometabolic risk factors and health-related qualities of life in women with metabolic syndrome. Metab Clin Exp. 2010;59(7):1035–43.CrossRefPubMed Oh EG, Bang SY, Kim SH, Chu SH, Jeon JY, Im JA, et al. Effects of a 6-month lifestyle modification intervention on the cardiometabolic risk factors and health-related qualities of life in women with metabolic syndrome. Metab Clin Exp. 2010;59(7):1035–43.CrossRefPubMed
31.
Zurück zum Zitat Matsuo T, Kim MK, Murotake Y, Numao S, Kim MJ, Ohkubo H, et al. Indirect lifestyle intervention through wives improves metabolic syndrome components in men. Int J Obes. 2009;34(1):136–45.CrossRef Matsuo T, Kim MK, Murotake Y, Numao S, Kim MJ, Ohkubo H, et al. Indirect lifestyle intervention through wives improves metabolic syndrome components in men. Int J Obes. 2009;34(1):136–45.CrossRef
32.
Zurück zum Zitat Mcmahon GT, Gomes HE, Hickson HS, Hu TM, Levine BA, Conlin PR. Web-based care management in patients with poorly controlled diabetes. Diab Care. 2005;28:1624–9.CrossRef Mcmahon GT, Gomes HE, Hickson HS, Hu TM, Levine BA, Conlin PR. Web-based care management in patients with poorly controlled diabetes. Diab Care. 2005;28:1624–9.CrossRef
33.
Zurück zum Zitat Izquierdo RE, Knudson PE, Meyer S, Kearns J, Ploutzsnyder R, Weinstock RS. A comparison of diabetes education administered through telemedicine versus in person. Diab Care. 2003;26:1002–7.CrossRef Izquierdo RE, Knudson PE, Meyer S, Kearns J, Ploutzsnyder R, Weinstock RS. A comparison of diabetes education administered through telemedicine versus in person. Diab Care. 2003;26:1002–7.CrossRef
34.
Zurück zum Zitat Moore TJ, Alsabeeh N, Apovian CM, Murphy MC, Coffman GA, Cullum-Dugan D. Weight, blood pressure, and dietary benefits after 12 months of a Web-based Nutrition Education Program (DASH for health): longitudinal observational study. J Med Internet Res. 2008;10(4):e 52.CrossRef Moore TJ, Alsabeeh N, Apovian CM, Murphy MC, Coffman GA, Cullum-Dugan D. Weight, blood pressure, and dietary benefits after 12 months of a Web-based Nutrition Education Program (DASH for health): longitudinal observational study. J Med Internet Res. 2008;10(4):e 52.CrossRef
35.
Zurück zum Zitat Oenema A, Brug J, Lechner L. Web-based tailored nutrition education: results of a randomized controlled trial. Health Educ Res. 2001;16(6):647–60.CrossRefPubMed Oenema A, Brug J, Lechner L. Web-based tailored nutrition education: results of a randomized controlled trial. Health Educ Res. 2001;16(6):647–60.CrossRefPubMed
36.
Zurück zum Zitat Gold BC, Burke S, Pintauro S, Buzzell P, Harveya- Berino J. Weight loss on the web: a pilot study comparing a structured behavioral intervention to a commercial program. Obesity. 2007;15(1):155–64.CrossRefPubMed Gold BC, Burke S, Pintauro S, Buzzell P, Harveya- Berino J. Weight loss on the web: a pilot study comparing a structured behavioral intervention to a commercial program. Obesity. 2007;15(1):155–64.CrossRefPubMed
37.
Zurück zum Zitat Jackson LA, Ervin KS, Gardner PD, Schmitt N. Gender and the Internet: women communicating and men searching. Sex Roles. 2001;44(5/6):363–79.CrossRef Jackson LA, Ervin KS, Gardner PD, Schmitt N. Gender and the Internet: women communicating and men searching. Sex Roles. 2001;44(5/6):363–79.CrossRef
38.
Zurück zum Zitat Mirinazhad MM, Farhangi MA, Jahangiri L, Yaghoubi A. Serum adiponectin concentrations in relation to lipid profile, anthropometric variables and insulin resistance in patients with metabolic syndrome. Mal J Nutr. 2014;20(3):283–9. Mirinazhad MM, Farhangi MA, Jahangiri L, Yaghoubi A. Serum adiponectin concentrations in relation to lipid profile, anthropometric variables and insulin resistance in patients with metabolic syndrome. Mal J Nutr. 2014;20(3):283–9.
39.
Zurück zum Zitat Feizollahzadeh S, Rasuli J, Kheirouri S, Alizadeh M. Augmented plasma adiponectin after prolonged fasting during Ramadan in men. HPP. 2014;4(1):77–81.PubMedPubMedCentral Feizollahzadeh S, Rasuli J, Kheirouri S, Alizadeh M. Augmented plasma adiponectin after prolonged fasting during Ramadan in men. HPP. 2014;4(1):77–81.PubMedPubMedCentral
Metadaten
Titel
A web-based interactive lifestyle modification program improves lipid profile and serum adiponectin concentrations in patients with metabolic syndrome: the “Red Ruby” study
verfasst von
Mahdieh Abbasalizad Farhangi
Leila Jahangiry
Mir-Mousa Mirinazhad
Davoud Shojaeezade
Ali Montazeri
Alireza Yaghoubi
Publikationsdatum
03.05.2015
Verlag
Springer India
Erschienen in
International Journal of Diabetes in Developing Countries / Ausgabe 1/2017
Print ISSN: 0973-3930
Elektronische ISSN: 1998-3832
DOI
https://doi.org/10.1007/s13410-015-0395-z

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