Erschienen in:
01.11.2006 | Oral Presentation
Aberrant activation of Notch signalling in human breast cancer
verfasst von:
S Stylianou, GM Collu, RB Clarke, K Brennan
Erschienen in:
Breast Cancer Research
|
Sonderheft 2/2006
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Excerpt
Like many developmental signalling pathways, the Notch pathway has been linked to the aetiology of several different human cancers. The development of focal adenocarcinomas in the murine mammary gland [
1] and the transformation of both normal murine and human breast epithelial cell lines following Notch activation [
1,
2] have long suggested that the pathway may play a role in human breast cancer. However, this question has received little attention. …