Ausgabe 2/2013
Inhalt (11 Artikel)
Hippocampal sclerosis of aging, a prevalent and high-morbidity brain disease
Peter T. Nelson, Charles D. Smith, Erin L. Abner, Bernard J. Wilfred, Wang-Xia Wang, Janna H. Neltner, Michael Baker, David W. Fardo, Richard J. Kryscio, Stephen W. Scheff, Gregory A. Jicha, Kurt A. Jellinger, Linda J. Van Eldik, Frederick A. Schmitt
Clustering of plaques contributes to plaque growth in a mouse model of Alzheimer’s disease
Joanna F. McCarter, Sabine Liebscher, Teresa Bachhuber, Claudia Abou-Ajram, Mark Hübener, Bradley T. Hyman, Christian Haass, Melanie Meyer-Luehmann
N-truncated amyloid β (Aβ) 4-42 forms stable aggregates and induces acute and long-lasting behavioral deficits
Yvonne Bouter, Katharina Dietrich, Jessica L. Wittnam, Nasrollah Rezaei-Ghaleh, Thierry Pillot, Sophie Papot-Couturier, Thomas Lefebvre, Frederick Sprenger, Oliver Wirths, Markus Zweckstetter, Thomas A. Bayer
mTOR-dependent abnormalities in autophagy characterize human malformations of cortical development: evidence from focal cortical dysplasia and tuberous sclerosis
Shireena A. Yasin, Abu M. Ali, Mathew Tata, Simon R. Picker, Glenn W. Anderson, Elizabeth Latimer-Bowman, Sarah L. Nicholson, William Harkness, J. Helen Cross, Simon M. L. Paine, Thomas S. Jacques
Long-duration epilepsy affects cell morphology and glutamatergic synapses in type IIB focal cortical dysplasia
Adele Finardi, Francesca Colciaghi, Laura Castana, Denise Locatelli, Carlo Efisio Marras, Paola Nobili, Maddalena Fratelli, Manuela Adele Bramerio, Giorgio LoRusso, Giorgio Stefano Battaglia
HPA axis activity in multiple sclerosis correlates with disease severity, lesion type and gene expression in normal-appearing white matter
Jeroen Melief, Stella J. de Wit, Corbert G. van Eden, Charlotte Teunissen, Jörg Hamann, Bernard M. Uitdehaag, Dick Swaab, Inge Huitinga
MicroRNA-124 protects against focal cerebral ischemia via mechanisms involving Usp14-dependent REST degradation
Thorsten R. Doeppner, Maria Doehring, Eva Bretschneider, Anil Zechariah, Britta Kaltwasser, Barbara Müller, Jan C. Koch, Mathias Bähr, Dirk M. Hermann, Uwe Michel
Upregulating mutations in the TERT promoter commonly occur in adult malignant gliomas and are strongly associated with total 1p19q loss
Hideyuki Arita, Yoshitaka Narita, Shintaro Fukushima, Kensuke Tateishi, Yuko Matsushita, Akihiko Yoshida, Yasuji Miyakita, Makoto Ohno, V. Peter Collins, Nobutaka Kawahara, Soichiro Shibui, Koichi Ichimura
Codeletion of 1p and 19q determines distinct gene methylation and expression profiles in IDH-mutated oligodendroglial tumors
Pilar Mur, Manuela Mollejo, Yolanda Ruano, Ángel Rodríguez de Lope, Concepción Fiaño, Juan Fernando García, Javier S. Castresana, Aurelio Hernández-Laín, Juan A. Rey, Bárbara Meléndez
Differential expression and methylation of brain developmental genes define location-specific subsets of pilocytic astrocytoma
Sally R. Lambert, Hendrik Witt, Volker Hovestadt, Manuela Zucknick, Marcel Kool, Danita M. Pearson, Andrey Korshunov, Marina Ryzhova, Koichi Ichimura, Nada Jabado, Adam M. Fontebasso, Peter Lichter, Stefan M. Pfister, V. Peter Collins, David T. W. Jones
Amyloid-β may be released from non-junctional varicosities of axons generated from abnormal tau-containing brainstem nuclei in sporadic Alzheimer’s disease: a hypothesis
Heiko Braak, Kelly Del Tredici