Ausgabe 5/2020
Inhalt (13 Artikel)
The role of hnRNPs in frontotemporal dementia and amyotrophic lateral sclerosis
Alexander Bampton, Lauren M. Gittings, Pietro Fratta, Tammaryn Lashley, Ariana Gatt
C9orf72 loss-of-function: a trivial, stand-alone or additive mechanism in C9 ALS/FTD?
Elke Braems, Bart Swinnen, Ludo Van Den Bosch
Antibody against TDP-43 phosphorylated at serine 375 suggests conformational differences of TDP-43 aggregates among FTLD–TDP subtypes
Manuela Neumann, Petra Frick, Francesca Paron, Jonas Kosten, Emanuele Buratti, Ian R. Mackenzie
Distinct clinicopathologic clusters of persons with TDP-43 proteinopathy
Yuriko Katsumata, Erin L. Abner, Shama Karanth, Merilee A. Teylan, Charles N. Mock, Matthew D. Cykowski, Edward B. Lee, Kevin L. Boehme, Shubhabrata Mukherjee, John S. K. Kauwe, Richard J. Kryscio, Frederick A. Schmitt, David W. Fardo, Peter T. Nelson
Degeneration of the locus coeruleus is a common feature of tauopathies and distinct from TDP-43 proteinopathies in the frontotemporal lobar degeneration spectrum
Daniel T. Ohm, Claire Peterson, Rebecca Lobrovich, Katheryn A. Q. Cousins, Garrett S. Gibbons, Corey T. McMillan, David A. Wolk, Vivianna Van Deerlin, Lauren Elman, Meredith Spindler, Andres Deik, Andrew Siderowf, John Q. Trojanowski, Edward B. Lee, Murray Grossman, David J. Irwin
TDP-43 transports ribosomal protein mRNA to regulate axonal local translation in neuronal axons
Seiichi Nagano, Junki Jinno, Rehab F. Abdelhamid, Yinshi Jin, Megumi Shibata, Shohei Watanabe, Sachiko Hirokawa, Masatoyo Nishizawa, Kenji Sakimura, Osamu Onodera, Hironori Okada, Takashi Okada, Yuko Saito, Junko Takahashi-Fujigasaki, Shigeo Murayama, Shuji Wakatsuki, Hideki Mochizuki, Toshiyuki Araki
Extrinsic immune cell-derived, but not intrinsic oligodendroglial factors contribute to oligodendroglial differentiation block in multiple sclerosis
Laura Starost, Maren Lindner, Martin Herold, Yu Kang T. Xu, Hannes C. A. Drexler, Katharina Heß, Marc Ehrlich, Linda Ottoboni, Francesca Ruffini, Martin Stehling, Albrecht Röpke, Christian Thomas, Hans R. Schöler, Jack Antel, Jürgen Winkler, Gianvito Martino, Luisa Klotz, Tanja Kuhlmann
Insulin-like growth factor 2 (IGF2) protects against Huntington’s disease through the extracellular disposal of protein aggregates
Paula García-Huerta, Paulina Troncoso-Escudero, Di Wu, Arun Thiruvalluvan, Marisol Cisternas-Olmedo, Daniel R. Henríquez, Lars Plate, Pedro Chana-Cuevas, Cristian Saquel, Peter Thielen, Kenneth A. Longo, Brad J. Geddes, Gerardo Z. Lederkremer, Neeraj Sharma, Marina Shenkman, Swati Naphade, S. Pablo Sardi, Carlos Spichiger, Hans G. Richter, Felipe A. Court, Kizito Tshitoko Tshilenge, Lisa M. Ellerby, R. Luke Wiseman, Christian Gonzalez-Billault, Steven Bergink, Rene L. Vidal, Claudio Hetz
Germline-driven replication repair-deficient high-grade gliomas exhibit unique hypomethylation patterns
Andrew J. Dodgshun, Kohei Fukuoka, Melissa Edwards, Vanessa J. Bianchi, Anirban Das, Alexandra Sexton-Oates, Valérie Larouche, Magimairajan I. Vanan, Scott Lindhorst, Michal Yalon, Gary Mason, Bruce Crooks, Shlomi Constantini, Maura Massimino, Stefano Chiaravalli, Jagadeesh Ramdas, Warren Mason, Shamvil Ashraf, Roula Farah, An Van Damme, Enrico Opocher, Syed Ahmer Hamid, David S. Ziegler, David Samuel, Kristina A. Cole, Patrick Tomboc, Duncan Stearns, Gregory A. Thomas, Alexander Lossos, Michael Sullivan, Jordan R. Hansford, Alan Mackay, Chris Jones, David T. W. Jones, Vijay Ramaswamy, Cynthia Hawkins, Eric Bouffet, Uri Tabori
Dipeptide repeat protein and TDP-43 pathology along the hypothalamic–pituitary axis in C9orf72 and non-C9orf72 ALS and FTLD-TDP cases
Lieselot Dedeene, Evelien Van Schoor, Simona Ospitalieri, Alicja Ronisz, Jochen H. Weishaupt, Markus Otto, Albert C. Ludolph, Angelika Scheuerle, Rik Vandenberghe, Philip Van Damme, Koen Poesen, Dietmar Rudolf Thal
Segregation of ATP10B variants in families with autosomal recessive parkinsonism
Christelle Tesson, Ebba Lohmann, David Devos, Hélène Bertrand, Suzanne Lesage, Alexis Brice
Reply: Segregation of ATP10B variants in families with autosomal recessive Parkinsonism
Stefanie Smolders, Christine Van Broeckhoven
Correction to: ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer’s disease
Charles E. Evans, James S. Miners, Giulia Piva, Christine L. Willis, David M. Heard, Emma J. Kidd, Mark A. Good, Patrick G. Kehoe