Skip to main content
Erschienen in: Zeitschrift für Rheumatologie 2/2006

01.03.2006 | Leitthema

Aktivitätsscore-basierte Therapieadaptation bei chronischer Polyarthritis

verfasst von: Dr. K. P. Machold, V. P. K. Nell, D. Aletaha, J. S. Smolen, T. A. Stamm

Erschienen in: Zeitschrift für Rheumatologie | Ausgabe 2/2006

Einloggen, um Zugang zu erhalten

Zusammenfassung

Die in den letzten Jahren entwickelten validierten Aktivitätsscores für die chronische Polyarthritis erlauben eine longitudinale Dokumentation der Effektivität der angewendeten Therapiestrategien. Durch Anwendung der Aktivitätsscores in der täglichen Routine und bei jeder Visite könnte unter vergleichsweise geringem Aufwand die Behandlung der Patienten mit chronischer Polyarthritis deutlich verbessert werden. In diesem Überblick wird die Evidenz für einen Nutzen der Anwendung dieser Scores in der klinischen Routine dargestellt.
Literatur
1.
Zurück zum Zitat Aletaha D, Nell VP, Stamm T et al. (2005 a) Acute phase reactants add little to composite disease activity indices for rheumatoid arthritis: validation of a clinical activity score. Arthritis Res Ther 7:R796–R806CrossRefPubMedPubMedCentral Aletaha D, Nell VP, Stamm T et al. (2005 a) Acute phase reactants add little to composite disease activity indices for rheumatoid arthritis: validation of a clinical activity score. Arthritis Res Ther 7:R796–R806CrossRefPubMedPubMedCentral
2.
Zurück zum Zitat Aletaha D, Ward MM, Machold KP et al. (2005 b) Remission and active disease in rheumatoid arthritis — Defining criteria for disease activity states. Arthritis Rheum 52:2625–2636CrossRefPubMed Aletaha D, Ward MM, Machold KP et al. (2005 b) Remission and active disease in rheumatoid arthritis — Defining criteria for disease activity states. Arthritis Rheum 52:2625–2636CrossRefPubMed
3.
Zurück zum Zitat Boers M, Verhoeven AC, Markusse HM et al. (1997) Randomised comparison of combined step-down prednisolone, methotrexate and sulphasalazine with sulphasalazine alone in early rheumatoid arthritis. Lancet 350:309–318CrossRefPubMed Boers M, Verhoeven AC, Markusse HM et al. (1997) Randomised comparison of combined step-down prednisolone, methotrexate and sulphasalazine with sulphasalazine alone in early rheumatoid arthritis. Lancet 350:309–318CrossRefPubMed
4.
Zurück zum Zitat Fransen J, Langenegger T, Michel BA, Stucki G (2000) Feasibility and validity of the RADAI, a self-administered rheumatoid arthritis disease activity index. Rheumatology (Oxford) 39:321–327 Fransen J, Langenegger T, Michel BA, Stucki G (2000) Feasibility and validity of the RADAI, a self-administered rheumatoid arthritis disease activity index. Rheumatology (Oxford) 39:321–327
5.
Zurück zum Zitat Fransen J, Stucki G, Twisk J et al. (2003) Effectiveness of a measurement feedback system on outcome in rheumatoid arthritis: a controlled clinical trial. Ann Rheum Dis 62:624–629CrossRefPubMedPubMedCentral Fransen J, Stucki G, Twisk J et al. (2003) Effectiveness of a measurement feedback system on outcome in rheumatoid arthritis: a controlled clinical trial. Ann Rheum Dis 62:624–629CrossRefPubMedPubMedCentral
6.
Zurück zum Zitat Fransen J, Moens HB, Speyer I, van Riel PLCM (2005) Effectiveness of systematic monitoring of rheumatoid arthritis disease activity in daily practice: a multicentre, cluster randomised controlled trial. Ann Rheum Dis 64:1294–1298CrossRefPubMedPubMedCentral Fransen J, Moens HB, Speyer I, van Riel PLCM (2005) Effectiveness of systematic monitoring of rheumatoid arthritis disease activity in daily practice: a multicentre, cluster randomised controlled trial. Ann Rheum Dis 64:1294–1298CrossRefPubMedPubMedCentral
7.
Zurück zum Zitat Goekoop-Ruiterman YPM, Vries-Bouwstra JK, Allaart CF et al. (2005) Clinical and radiographic outcomes of four different treatment strategies in patients with early rheumatoid arthritis (the BeSt study) — A randomized, controlled trial. Arthritis Rheum 52:3381–3390CrossRefPubMed Goekoop-Ruiterman YPM, Vries-Bouwstra JK, Allaart CF et al. (2005) Clinical and radiographic outcomes of four different treatment strategies in patients with early rheumatoid arthritis (the BeSt study) — A randomized, controlled trial. Arthritis Rheum 52:3381–3390CrossRefPubMed
8.
Zurück zum Zitat Grigor C, Capell H, Stirling A et al. (2004) Effect of a treatment strategy of tight control for rheumatoid arthritis (the TICORA study): a single-blind randomised controlled trial. Lancet 364:263–269CrossRefPubMed Grigor C, Capell H, Stirling A et al. (2004) Effect of a treatment strategy of tight control for rheumatoid arthritis (the TICORA study): a single-blind randomised controlled trial. Lancet 364:263–269CrossRefPubMed
9.
Zurück zum Zitat Maini RN, Breedveld FC, Kalden JR et al. (1998) Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor alpha monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis. Arthritis Rheum 41:1552–1563CrossRefPubMed Maini RN, Breedveld FC, Kalden JR et al. (1998) Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor alpha monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis. Arthritis Rheum 41:1552–1563CrossRefPubMed
10.
Zurück zum Zitat Mottonen T, Hannonen P, Leirisalo-Repo M et al. (1999) Comparison of combination therapy with single-drug therapy in early rheumatoid arthritis: a randomised trial. FIN-RACo trial group. Lancet 353:1568–1573CrossRefPubMed Mottonen T, Hannonen P, Leirisalo-Repo M et al. (1999) Comparison of combination therapy with single-drug therapy in early rheumatoid arthritis: a randomised trial. FIN-RACo trial group. Lancet 353:1568–1573CrossRefPubMed
11.
Zurück zum Zitat Pincus T, Segurado OG (2006) Most visits of most patients with rheumatoid arthritis to most rheumatologists do not include a formal quantiatative joint count. Ann Rheum Dis (epub ahead of print) Pincus T, Segurado OG (2006) Most visits of most patients with rheumatoid arthritis to most rheumatologists do not include a formal quantiatative joint count. Ann Rheum Dis (epub ahead of print)
12.
Zurück zum Zitat Rau R, Wassenberg S, Herborn G et al. (1998) A new method of scoring radiographic change in rheumatoid arthritis. J Rheumatol 25:2094–2107PubMed Rau R, Wassenberg S, Herborn G et al. (1998) A new method of scoring radiographic change in rheumatoid arthritis. J Rheumatol 25:2094–2107PubMed
13.
Zurück zum Zitat Smolen JS, Kalden JR, Scott DL et al., The European Leflunomide Study Group (1999) Efficacy and safety of leflunomide compared with placebo and sulphasalazine in active rheumatoid arthritis: a double-blind, randomized, multicentre trial. Lancet 353:259–265CrossRefPubMed Smolen JS, Kalden JR, Scott DL et al., The European Leflunomide Study Group (1999) Efficacy and safety of leflunomide compared with placebo and sulphasalazine in active rheumatoid arthritis: a double-blind, randomized, multicentre trial. Lancet 353:259–265CrossRefPubMed
14.
Zurück zum Zitat Smolen JS, Aletaha D, Keystone E (2005) Superior efficacy of combination therapy for rheumatoid arthritis. Fact or fiction? Arthritis Rheum 52:2975–2983CrossRefPubMed Smolen JS, Aletaha D, Keystone E (2005) Superior efficacy of combination therapy for rheumatoid arthritis. Fact or fiction? Arthritis Rheum 52:2975–2983CrossRefPubMed
15.
Zurück zum Zitat Strand V, Cohen S, Schiff M et al. (1999) Treatment of active rheumatoid arthritis with leflunomide compared with placebo and methotrexate. Arch Intern Med 159:2542–2550CrossRefPubMed Strand V, Cohen S, Schiff M et al. (1999) Treatment of active rheumatoid arthritis with leflunomide compared with placebo and methotrexate. Arch Intern Med 159:2542–2550CrossRefPubMed
16.
Zurück zum Zitat Uitz E, Fransen J, Langenegger T, Stucki G (2000) Clinical quality management in rheumatoid arthritis: putting theory into practice. Swiss Clinical Quality Management in Rheumatoid Arthritis. Rheumatology (Oxford) 39:542–549 Uitz E, Fransen J, Langenegger T, Stucki G (2000) Clinical quality management in rheumatoid arthritis: putting theory into practice. Swiss Clinical Quality Management in Rheumatoid Arthritis. Rheumatology (Oxford) 39:542–549
17.
Zurück zum Zitat Van der Heijde D (2000) How to read radiographs according to the Sharp/van der Heijde method. J Rheumatol 27:261–263 Van der Heijde D (2000) How to read radiographs according to the Sharp/van der Heijde method. J Rheumatol 27:261–263
18.
Zurück zum Zitat Van der Heijde DM, van’t Hof M, van Riel PL, van de Putte LB (1993) Development of a disease activity score based on judgment in clinical practice by rheumatologists. J Rheumatol 20:579–581 Van der Heijde DM, van’t Hof M, van Riel PL, van de Putte LB (1993) Development of a disease activity score based on judgment in clinical practice by rheumatologists. J Rheumatol 20:579–581
19.
Zurück zum Zitat Van Gestel AM, Anderson JJ, van Riel PL et al. (1999) ACR and EULAR improvement criteria have comparable validity in rheumatoid arthritis trials. American College of Rheumatology European League of Associations for Rheumatology. J Rheumatol 26:705–711 Van Gestel AM, Anderson JJ, van Riel PL et al. (1999) ACR and EULAR improvement criteria have comparable validity in rheumatoid arthritis trials. American College of Rheumatology European League of Associations for Rheumatology. J Rheumatol 26:705–711
20.
Zurück zum Zitat Weinblatt ME, Coblyn JS, Fox DA et al. (1985) Efficacy of low-dose methotrexate in rheumatoid arthritis. N Engl J Med 312:818–822CrossRefPubMed Weinblatt ME, Coblyn JS, Fox DA et al. (1985) Efficacy of low-dose methotrexate in rheumatoid arthritis. N Engl J Med 312:818–822CrossRefPubMed
21.
Zurück zum Zitat Weinblatt ME, Trentham DE, Fraser PA et al. (1988) Long-term prospective trial of low-dose methotrexate in rheumatoid arthritis. Arthritis Rheum 31:167–175CrossRefPubMed Weinblatt ME, Trentham DE, Fraser PA et al. (1988) Long-term prospective trial of low-dose methotrexate in rheumatoid arthritis. Arthritis Rheum 31:167–175CrossRefPubMed
22.
Zurück zum Zitat Weinblatt ME, Kremer JM, Bankhurst AD et al. (1999) A trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate. N Engl J Med 340:253–259CrossRefPubMed Weinblatt ME, Kremer JM, Bankhurst AD et al. (1999) A trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate. N Engl J Med 340:253–259CrossRefPubMed
23.
Zurück zum Zitat Weinblatt ME, Keystone EC, Furst DE et al. (2003) Adalimumab, a fully human anti-tumor necrosis factor a monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate — The ARMADA trial. Arthritis Rheum 48:35–45CrossRefPubMed Weinblatt ME, Keystone EC, Furst DE et al. (2003) Adalimumab, a fully human anti-tumor necrosis factor a monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate — The ARMADA trial. Arthritis Rheum 48:35–45CrossRefPubMed
Metadaten
Titel
Aktivitätsscore-basierte Therapieadaptation bei chronischer Polyarthritis
verfasst von
Dr. K. P. Machold
V. P. K. Nell
D. Aletaha
J. S. Smolen
T. A. Stamm
Publikationsdatum
01.03.2006
Verlag
Springer Berlin Heidelberg
Erschienen in
Zeitschrift für Rheumatologie / Ausgabe 2/2006
Print ISSN: 0340-1855
Elektronische ISSN: 1435-1250
DOI
https://doi.org/10.1007/s00393-006-0036-5

Weitere Artikel der Ausgabe 2/2006

Zeitschrift für Rheumatologie 2/2006 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.