nach oben

Drugs in R&D

Erschienen in:

01.11.2007 | Adis R&D Profile

Amoxicillin Pulsatile — MiddleBrook

APC 111, APC-111, PULSYS-Enhanced Amoxicillin

Erschienen in: Drugs in R&D | Ausgabe 6/2007

Einloggen, um Zugang zu erhalten

Excerpt

MiddleBrook Pharmaceuticals (formerly Advancis Pharmaceutical) is developing an improved version of amoxicillin using its pulsatile oral drug delivery technology, called PULSYS™. Amoxicillin PULSYS™ is intended to provide a lower treatment dose, once-daily alternative to currently approved amoxicillin and penicillin regimens for the treatment of adolescents/adults with pharyngitis and/or tonsillitis. If amoxicillin PULSYS™ is approved, it will be the first and only once-daily amoxicillin therapy approved for use in the US. Regulatory submissions for the treatment of pharyngitis/tonsillitis have been made in the US. Amoxicillin PULSYS™ is in clinical development for the treatment of pharyngitis and/or tonsillitis due to group A streptococcal infections in adolescents/adults as a tablet formulation. MiddleBrook was conducting clinical development of a sprinkle formulation for children. However, this has been put on hold for financial reasons. …

MiddleBrook Pharmaceuticals Inc. Advancis Pharmaceutical Changes Its Name to MiddleBrook Pharmaceuticals, Inc. Media Release: 28 Jun 2007. Available from URL: http://www.middlebrookpharma.com

Par Pharmaceutical Companies Inc. Par Pharmaceutical Finalizes Amoxicillin PULSYS Agreement With Advancis Pharmaceutical. Media Release: 2 Jun 2004. Available from URL: http://www.parpharm.com

Advancis Pharmaceutical Corporation. Advancis Pharmaceutical Announces Partner For Amoxicillin PULSYS Product Candidate. Media Release: 2 Mar 2004. Available from URL: http://www.advancispharm.com

Advancis Pharmaceutical Corporation. Advancis Pharmaceutical Reports Second Quarter 2005 Results. Media Release: 4 Aug 2005. Available from URL: http://www.advancispharm.com

Advancis Pharmaceutical Corporation. Advancis Pharmaceutical Reports First Quarter 2005 Results. Media Release: 27 Apr 2005. Available from URL: http://www.advancispharm.com

Advancis Pharmaceutical Corporation. Advancis Pharmaceutical Closes Private Placement of Common Equity Raising $24 Million. Media Release: 18 Apr 2007. Available from URL: http://www.advancispharm.com

Advancis Pharmaceutical Corporation. Advancis Pharmaceutical to Raise $24 Million Through Private Placement of Common Equity. Media Release: 9 Apr 2007. Available from URL: http://www.advancispharm.com

Advancis Pharmaceutical Corporation. Advancis Pharmaceutical On Track to File NDA for Amoxicillin PULSYS. Media Release: 13 Sep 2006. Available from URL: http://www.advancispharm.com

Advancis Pharmaceutical Corporation. Advancis Pharmaceutical Announces Positive Results for Amoxicillin PULSYS Phase III Trial. Media Release: 10 Aug 2006. Available from URL: http://www.advancispharm.com

10.

Advancis Pharmaceutical Corporation. Advancis Pharmaceutical Reports Third Quarter 2006 Results. Media Release: 1 Nov 2006. Available from URL: http://www.advancispharm.com

11.

Advancis Pharmaceutical Corporation. Advancis Pharmaceutical to Raise $18 Million Through Private Placement of Common Equity. Media Release: 11 Dec 2006. Available from URL: http://www.advancispharm.com

12.

Advancis Pharmaceutical Corporation, Par Pharmaceutical Companies. Advancis Pharmaceutical Announces Results From Adult/Adolescent Amoxicillin PULSYS Phase III Trial. Media Release: 15 Jun 2005. Available from URL: http://www.advancispharm.com

13.

Advancis Pharmaceutical Corporation. Advancis Pharmaceutical Completes Enrollment in Amoxicillin PULSYS Phase III Trial. Media Release: 1 Jun 2006. Available from URL: http://www.advancispharm.com

14.

Advancis Pharmaceutical Corporation. Advancis Pharmaceutical Completes Enrollment in Adult/Adolescent Amoxicillin PULSYS Phase III Trial. Media Release: 29 Mar 2005. Available from URL: http://www.advancispharm.com

15.

Advancis Pharmaceutical Corporation. Advancis Pharmaceutical to Begin Pediatric Amoxicillin PULSYS Phase III Trial. Media Release: 17 Dec 2004. Available from URL: http://www.advancispharm.com

16.

Advancis Pharmaceutical Corporation. Advancis Pharmaceutical Announces Results from Pediatric Amoxicillin PULSYS Phase III Trial. Media Release: 21 Jul 2005. Available from URL: http://www.advancispharm.com

Titel: Amoxicillin Pulsatile — MiddleBrook
APC 111, APC-111, PULSYS-Enhanced Amoxicillin
Publikationsdatum: 01.11.2007
Verlag: Springer International Publishing
Erschienen in: Drugs in R&D / Ausgabe 6/2007
Print ISSN: 1174-5886
Elektronische ISSN: 1179-6901
DOI: https://doi.org/10.2165/00126839-200708060-00007

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

Amoxicillin Pulsatile — MiddleBrook

APC 111, APC-111, PULSYS-Enhanced Amoxicillin

Excerpt

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

Excerpt

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 6/2007

Penetration of Prulifloxacin into Gynaecological Tissues after Single and Repeated Oral Administrations

MN 001

Alkylation Activity and Molecular Properties of Two Antineoplastic Agents that Utilise Indometacin and a Conjugate of Aspirin with 2-Aminonicotinic Acid to Transport Nitrogen Mustard Groups

Influence of Piperine on the Pharmacokinetics of Nevirapine under Fasting Conditions

Improving Early Drug Discovery through ADME Modelling

The Rebif® New Formulation Story