Erschienen in:
09.10.2017 | Commentary
An optimal design for the study of palliative sedation—making somewhat better pictures
verfasst von:
Hong Yup Ahn, So Jung Park, Hee Kyung Ahn, In Cheol Hwang
Erschienen in:
Supportive Care in Cancer
|
Ausgabe 1/2018
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Excerpt
Palliative sedation refers to the use of sedatives to reduce the consciousness level of patients with the aim of relieving symptoms refractory to any other means of treatment [
1]. Among the forms of palliative sedation, continuous deep sedation (CDS) is at the top of a debate concerning the possibility that the greatest effect of palliative sedation is the shortening of life [
2]. CDS can trigger lethal pathophysiological cascades related to the pharmacological effects of high-dose sedatives on the respiratory and circulation system [
3]. The clinical evidence currently available may set families and palliative care providers free of the guilty feelings associated with hastening a patient’s death [
4]. In both ethics and practice, the clarification of whether a forced loss of consciousness curtails a patient’s survival is still of great value. …