Ausgabe 1/2015
Inhalt (384 Artikel)
A genetic study on C5-TRAF1 and progression of joint damage in rheumatoid arthritis
Hanna W van Steenbergen, Luis Rodríguez-Rodríguez, Ewa Berglin, Alexandra Zhernakova, Rachel Knevel, Jose Ivorra-Cortés, Tom WJ Huizinga, Benjamin Fernández-Gutiérrez, Peter K Gregersen, Solbritt Rantapää-Dahlqvist, Annette HM van der Helm-van Mil
Separate and overlapping specificities in rheumatoid arthritis antibodies binding to citrulline- and homocitrulline-containing peptides related to type I and II collagen telopeptides
Sanna Turunen, Pekka Hannonen, Marja-Kaisa Koivula, Leila Risteli, Juha Risteli
Application of the 2012 Systemic Lupus International Collaborating Clinics classification criteria to patients in a regional Swedish systemic lupus erythematosus register
Anna Ighe, Örjan Dahlström, Thomas Skogh, Christopher Sjöwall
Increasing expression of substance P and calcitonin gene-related peptide in synovial tissue and fluid contribute to the progress of arthritis in developmental dysplasia of the hip
Hui Wang, Xiang Zhang, Ji-Ye He, Xin-Feng Zheng, De Li, Zheng Li, Jun-Feng Zhu, Chao Shen, Gui-Quan Cai, Xiao-Dong Chen
Overexpression of cystatin C in synovium does not reduce synovitis or cartilage degradation in established osteoarthritis
Sirkka Kyostio-Moore, Susan Piraino, Patricia Berthelette, Nance Moran, Joseph Serriello, Alison Bendele, Cathleen Sookdeo, Bindu Nambiar, Patty Ewing, Donna Armentano, Gloria L Matthews
CD55 deposited on synovial collagen fibers protects from immune complex-mediated arthritis
Olga N Karpus, Hans P Kiener, Birgit Niederreiter, A Seda Yilmaz-Elis, Jos van der Kaa, Valeria Ramaglia, Ramon Arens, Josef S Smolen, Marina Botto, Paul P Tak, J Sjef Verbeek, Jörg Hamann
A comparison of the predictive accuracy of three screening models for pulmonary arterial hypertension in systemic sclerosis
Yanjie Hao, Vivek Thakkar, Wendy Stevens, Kathleen Morrisroe, David Prior, Candice Rabusa, Peter Youssef, Eli Gabbay, Janet Roddy, Jennifer Walker, Jane Zochling, Joanne Sahhar, Peter Nash, Susan Lester, Maureen Rischmueller, Susanna M Proudman, Mandana Nikpour
Anti-type II collagen immune complex-induced granulocyte reactivity is associated with joint erosions in RA patients with anti-collagen antibodies
Vivek Anand Manivel, Azita Sohrabian, Marius C Wick, Mohammed Mullazehi, Lena Douhan Håkansson, Johan Rönnelid
Expression of citrulline and homocitrulline residues in the lungs of non-smokers and smokers: implications for autoimmunity in rheumatoid arthritis
Elena B Lugli, Raquel ESM Correia, Roman Fischer, Karin Lundberg, Ken R Bracke, Anna B Montgomery, Benedikt M Kessler, Guy G Brusselle, Patrick J Venables
Peripheral blood CD4+CD25+CD127low regulatory T cells are significantly increased by tocilizumab treatment in patients with rheumatoid arthritis: increase in regulatory T cells correlates with clinical response
Jun Kikuchi, Misato Hashizume, Yuko Kaneko, Keiko Yoshimoto, Naoshi Nishina, Tsutomu Takeuchi
A cross-sectional study of pain sensitivity, disease-activity assessment, mental health, and fibromyalgia status in rheumatoid arthritis
Nalinie Joharatnam, Daniel F McWilliams, Deborah Wilson, Maggie Wheeler, Ira Pande, David A Walsh
Deficiency of fibroblast activation protein alpha ameliorates cartilage destruction in inflammatory destructive arthritis
Stefan Wäldele, Christina Koers-Wunrau, Denise Beckmann, Adelheid Korb-Pap, Corinna Wehmeyer, Thomas Pap, Berno Dankbar
Epidemiology and management of gout in Taiwan: a nationwide population study
Chang-Fu Kuo, Matthew J Grainge, Lai-Chu See, Kuang-Hui Yu, Shue-Fen Luo, Weiya Zhang, Michael Doherty
Golimumab in patients with active rheumatoid arthritis after treatment with tumor necrosis factor α inhibitors: findings with up to five years of treatment in the multicenter, randomized, double-blind, placebo-controlled, phase 3 GO-AFTER study
Josef S Smolen, Jonathan Kay, Mittie Doyle, Robert Landewé, Eric L Matteson, Norman Gaylis, Jürgen Wollenhaupt, Frederick T Murphy, Stephen Xu, Yiying Zhou, Elizabeth C Hsia
Non-canonical NF-κB signaling in rheumatoid arthritis: Dr Jekyll and Mr Hyde?
Ae R Noort, Paul P Tak, Sander W Tas
Parietal and intravascular innate mechanisms of vascular inflammation
Giuseppe A Ramirez, Patrizia Rovere-Querini, Maria Grazia Sabbadini, Angelo A Manfredi
Proteasome inhibitors as experimental therapeutics of autoimmune diseases
Sue Ellen Verbrugge, Rik J Scheper, Willem F Lems, Tanja D de Gruijl, Gerrit Jansen
Patterns of health care utilization related to initiation of amitriptyline, duloxetine, gabapentin, or pregabalin in fibromyalgia
Seoyoung C Kim, Joan E Landon, Yvonne C Lee
Occupational risk factors for hip osteoarthritis are associated with early hip structural abnormalities: a 3.0 T magnetic resonance imaging study of community-based adults
Andrew J Teichtahl, Sam Smith, Yuanyuan Wang, Anita E Wluka, Richard O’Sullivan, Graham G Giles, Flavia M Cicuttini
Full-thickness cartilage defects are repaired via a microfracture technique and intraarticular injection of the small-molecule compound kartogenin
Xingquan Xu, Dongquan Shi, Yeshuai Shen, Zhihong Xu, Jin Dai, Dongyang Chen, Huajian Teng, Qing Jiang
Effects of exercise on depression in adults with arthritis: a systematic review with meta-analysis of randomized controlled trials
George A Kelley, Kristi S Kelley, Jennifer M Hootman
An important role for A20-binding inhibitor of nuclear factor-kB-1 (ABIN1) in inflammation-mediated endothelial dysfunction: an in vivo study in ABIN1 (D485N) mice
Naveed Akbar, Sambit Nanda, Jill Belch, Philip Cohen, Faisel Khan
Beer and wine consumption and risk of knee or hip osteoarthritis: a case control study
Stella G Muthuri, Weiya Zhang, Rose A Maciewicz, Kenneth Muir, Michael Doherty
Loss of sclerostin promotes osteoarthritis in mice via β-catenin-dependent and -independent Wnt pathways
Wafa Bouaziz, Thomas Funck-Brentano, Hilène Lin, Caroline Marty, Hang-Korng Ea, Eric Hay, Martine Cohen-Solal
Anti-carbamylated protein antibodies in the pre-symptomatic phase of rheumatoid arthritis, their relationship with multiple anti-citrulline peptide antibodies and association with radiological damage
Mikael Brink, Marije K Verheul, Johan Rönnelid, Ewa Berglin, Rikard Holmdahl, Rene EM Toes, Lars Klareskog, Leendert A Trouw, Solbritt Rantapää-Dahlqvist
IgG anti-apolipoprotein A-1 antibodies in patients with systemic lupus erythematosus are associated with disease activity and corticosteroid therapy: an observational study
Sara Croca, Paul Bassett, Sharon Chambers, Maria Davari, Karim Fouad Alber, Oliver Leach, Yiannis Ioannou, Ian Giles, David Isenberg, Anisur Rahman
Serum progranulin levels are elevated in dermatomyositis patients with acute interstitial lung disease, predicting prognosis
Atsushi Tanaka, Hiroshi Tsukamoto, Hiroki Mitoma, Chikako Kiyohara, Naoyasu Ueda, Masahiro Ayano, Shun-ichiro Ohta, Yasutaka Kimoto, Mitsuteru Akahoshi, Yojiro Arinobu, Hiroaki Niiro, Yoshifumi Tada, Takahiko Horiuchi, Koichi Akashi
Thyroid hormones enhance the biomechanical functionality of scaffold-free neocartilage
Jennifer K Lee, Courtney A Gegg, Jerry C Hu, A Hari Reddi, Kyriacos A Athanasiou
T-cell metabolism in autoimmune disease
Zhen Yang, Eric L Matteson, Jörg J Goronzy, Cornelia M Weyand
Effect of alendronate on post-traumatic osteoarthritis induced by anterior cruciate ligament rupture in mice
Mohammad S Khorasani, Sindi Diko, Allison W Hsia, Matthew J Anderson, Damian C Genetos, Dominik R Haudenschild, Blaine A Christiansen
CCAAT/enhancer-binding protein β promotes receptor activator of nuclear factor-kappa-B ligand (RANKL) expression and osteoclast formation in the synovium in rheumatoid arthritis
Hidetoshi Tsushima, Ken Okazaki, Kohei Ishihara, Takahiro Ushijima, Yukihide Iwamoto
Estrogen regulates T helper 17 phenotype and localization in experimental autoimmune arthritis
Annica Andersson, Alexandra Stubelius, Merja Nurkkala Karlsson, Cecilia Engdahl, Malin Erlandsson, Louise Grahnemo, Marie K Lagerquist, Ulrika Islander
Transcriptome analysis of ageing in uninjured human Achilles tendon
Mandy Jayne Peffers, Yongxiang Fang, Kathleen Cheung, Tim Koh Jia Wei, Peter David Clegg, Helen Lucy Birch
Prevalence, incidence and characteristics of the metabolic syndrome (MetS) in a cohort of Mexican Mestizo early rheumatoid arthritis patients treated with conventional disease modifying anti-rheumatic drugs: the complex relationship between MetS and disease activity
Federico Parra-Salcedo, Irazú Contreras-Yáñez, Daniel Elías-López, Carlos A Aguilar-Salinas, Virginia Pascual-Ramos
Regulatory T cell-deficient scurfy mice develop systemic autoimmune features resembling lupus-like disease
Eva N Hadaschik, Xiaoying Wei, Harald Leiss, Britta Heckmann, Birgit Niederreiter, Günter Steiner, Walter Ulrich, Alexander H Enk, Josef S Smolen, Georg H Stummvoll
Takayasu arteritis in childhood: retrospective experience from a tertiary referral centre in the United Kingdom
Despina Eleftheriou, Giulia Varnier, Pavla Dolezalova, Anne-Marie McMahon, Muthana Al-Obaidi, Paul A Brogan
Animal model of acute gout reproduces the inflammatory and ultrasonographic joint changes of human gout
Carlos Pineda, Arturo J Fuentes-Gómez, Cristina Hernández-Díaz, Yessica Zamudio-Cuevas, Javier Fernández-Torres, Ambar López-Macay, Ismael Alba-Sánchez, Javier Camacho-Galindo, Lucio Ventura, Luis E Gómez-Quiróz, María Concepción Gutiérrez-Ruíz, Francisco García-Vázquez, Anthony M Reginato, Marwin Gutiérrez, Alberto López-Reyes
Increased 30-day and 1-year mortality rates and lower coronary revascularisation rates following acute myocardial infarction in patients with autoimmune rheumatic disease
Sharon Van Doornum, Megan Bohensky, Mark A Tacey, Caroline A Brand, Vijaya Sundararajan, Ian P Wicks
Long-lived plasma cells are early and constantly generated in New Zealand Black/New Zealand White F1 mice and their therapeutic depletion requires a combined targeting of autoreactive plasma cells and their precursors
Adriano Taddeo, Laleh Khodadadi, Caroline Voigt, Imtiaz M Mumtaz, Qingyu Cheng, Katrin Moser, Tobias Alexander, Rudolf A Manz, Andreas Radbruch, Falk Hiepe, Bimba F Hoyer
Physical activity and risk of rheumatoid arthritis in women: a population-based prospective study
Daniela Di Giuseppe, Matteo Bottai, Johan Askling, Alicja Wolk
Role of C-reactive protein in osteoclastogenesis in rheumatoid arthritis
Kyoung-Woon Kim, Bo-Mi Kim, Hee-Won Moon, Sang-Heon Lee, Hae-Rim Kim
MicroRNA-33a regulates cholesterol synthesis and cholesterol efflux-related genes in osteoarthritic chondrocytes
Fotini Kostopoulou, Konstantinos N Malizos, Ioanna Papathanasiou, Aspasia Tsezou
Kinetics of gene expression and bone remodelling in the clinical phase of collagen-induced arthritis
Katja CM Denninger, Thomas Litman, Troels Marstrand, Kristian Moller, Lars Svensson, Tord Labuda, Åsa Andersson
Evaluation of the effect of ambrisentan on digital microvascular flow in patients with systemic sclerosis using laser Doppler perfusion imaging: a 12-week randomized double-blind placebo controlled trial
Nilanjana Bose, James Bena, Soumya Chatterjee
Haptoglobin-α1, -α2, vitamin D-binding protein and apolipoprotein C-III as predictors of etanercept drug response in rheumatoid arthritis
Sabine Blaschke, Kathinka Rinke, Michael Maring, Thomas Flad, Susann Patschan, Olaf Jahn, Claudia A Mueller, Gerhard A Mueller, Hassan Dihazi
Polychromatic flow cytometry in evaluating rheumatic disease patients
Chungwen Wei, Scott Jenks, Iñaki Sanz
Anti-factor Xa antibodies in patients with antiphospholipid syndrome and their effects upon coagulation assays
Bahar Artim-Esen, Charis Pericleous, Ian Mackie, Vera M Ripoll, David Latchman, David Isenberg, Anisur Rahman, Yiannis Ioannou, Ian Giles
Characterising deviation from treat-to-target strategies for early rheumatoid arthritis: the first three years
Nasir Wabe, Michael J Sorich, Mihir D Wechalekar, Leslie G Cleland, Leah McWilliams, Anita Lee, Llewellyn Spargo, Robert G Metcalf, Cindy Hall, Susanna M Proudman, Michael D Wiese
Circulating miRNAs as potential biomarkers of therapy effectiveness in rheumatoid arthritis patients treated with anti-TNFα
Carmen Castro-Villegas, Carlos Pérez-Sánchez, Alejandro Escudero, Ileana Filipescu, Miriam Verdu, Patricia Ruiz-Limón, Ma Angeles Aguirre, Yolanda Jiménez-Gomez, Pilar Font, Antonio Rodriguez-Ariza, Juan Ramon Peinado, Eduardo Collantes-Estévez, Rocío González-Conejero, Constantino Martinez, Nuria Barbarroja, Chary López-Pedrera
Non-invasive in vivo imaging of arthritis in a collagen-induced murine model with phosphatidylserine-binding near-infrared (NIR) dye
Marion M Chan, Brian D Gray, Koon Y Pak, Dunne Fong
Comparison of two hyaluronic acid formulations for safety and efficacy (CHASE) study in knee osteoarthritis: a multicenter, randomized, double-blind, 26-week non-inferiority trial comparing Durolane to Artz
Heng Zhang, Ke Zhang, Xianlong Zhang, Zhenan Zhu, Shigui Yan, Tiansheng Sun, Ai Guo, John Jones, R Grant Steen, Bin Shan, Jenny Zhang, Jianhao Lin
Significant effects of biologic therapy on lipid profiles and insulin resistance in patients with rheumatoid arthritis
Der-Yuan Chen, Yi-Ming Chen, Tsu-Yi Hsieh, Chia-Wei Hsieh, Chi-Chen Lin, Joung-Liang Lan
Altered balance of interleukin-13/interferon-gamma contributes to lacrimal gland destruction and secretory dysfunction in CD25 knockout model of Sjögren’s syndrome
Fang Bian, Flavia L Barbosa, Rosa M Corrales, Flavia SA Pelegrino, Eugene A Volpe, Stephen C Pflugfelder, Cintia S de Paiva
Mitochondrial respiration and redox coupling in articular chondrocytes
Rachel S Lane, Yao Fu, Satoshi Matsuzaki, Michael Kinter, Kenneth M Humphries, Timothy M Griffin
Carotid artery plaque in women with rheumatoid arthritis and low estimated cardiovascular disease risk: a cross-sectional study
Alfonso Corrales, Patrick H Dessein, Linda Tsang, Trinitario Pina, Ricardo Blanco, Carlos Gonzalez-Juanatey, Javier Llorca, Miguel A Gonzalez-Gay
CYB5A polymorphism increases androgens and reduces risk of rheumatoid arthritis in women
Klaus Stark, Rainer H Straub, Jozef Rovenský, Stanislava Blažičková, Gabriele Eiselt, Martin Schmidt
Anti-PM/Scl antibodies are found in Japanese patients with various systemic autoimmune conditions besides myositis and scleroderma
Yoshinao Muro, Yuji Hosono, Kazumitsu Sugiura, Yasushi Ogawa, Tsuneyo Mimori, Masashi Akiyama
Angiogenic gene expression and vascular density are reflected in ultrasonographic features of synovitis in early rheumatoid arthritis: an observational study
Stephen Kelly, Michele Bombardieri, Frances Humby, Nora Ng, Alessandra Marrelli, Sudeh Riahi, Maria DiCicco, Arti Mahto, Lu Zou, Debasish Pyne, Rebecca E Hands, Costantino Pitzalis
Subjective and objective levels of physical activity and their association with cardiorespiratory fitness in rheumatoid arthritis patients
Chen-an Yu, Peter C Rouse, Jet JCS Veldhuijzen Van Zanten, Nikos Ntoumanis, George D Kitas, Joan L Duda, George S Metsios
Effect of coculturing canine notochordal, nucleus pulposus and mesenchymal stromal cells for intervertebral disc regeneration
Irene TM Arkesteijn, Lucas A Smolders, Sandra Spillekom, Frank M Riemers, Esther Potier, Björn P Meij, Keita Ito, Marianna A Tryfonidou
CD27-IgD- memory B cells are modulated by in vivo interleukin-6 receptor (IL-6R) blockade in rheumatoid arthritis
Zafar Mahmood, Khalid Muhammad, Marc Schmalzing, Petra Roll, Thomas Dörner, Hans-Peter Tony
Thymic stromal lymphopoietin in hepatitis C virus-related cryoglobulinemic vasculitis: gene expression level and protein distribution
Domenico Sansonno, Sabino Russi, Silvia Sansonno, Fabio Pavone, Franco Dammacco
Rheumatoid arthritis response to treatment across IgG1 allotype – anti-TNF incompatibility: a case-only study
Ariana Montes, Eva Perez-Pampin, Federico Navarro-Sarabia, Virginia Moreira, Arturo Rodríguez de la Serna, Berta Magallares, Yiannis Vasilopoulos, Theologia Sarafidou, Antonio Fernández-Nebro, María del Carmen Ordóñez, Javier Narváez, Juan D Cañete, Ana Marquez, Dora Pascual-Salcedo, Beatriz Joven, Patricia Carreira, Manuel J Moreno-Ramos, Rafael Caliz, Miguel Angel Ferrer, Rosa Garcia-Portales, Francisco J Blanco, Cesar Magro, Enrique Raya, Lara Valor, Juan J Alegre-Sancho, Alejandro Balsa, Javier Martin, Darren Plant, John Isaacs, Ann W Morgan, Anne Barton, Anthony G Wilson, Juan J Gómez-Reino, Antonio Gonzalez
High mobility group box 1 contributes to anti-neutrophil cytoplasmic antibody-induced neutrophils activation through receptor for advanced glycation end products (RAGE) and Toll-like receptor 4
Chen Wang, Huan Wang, Dong-Yuan Chang, Jian Hao, Ming-Hui Zhao, Min Chen
The metastatic tumor antigen 1-transglutaminase-2 pathway is involved in self-limitation of monosodium urate crystal-induced inflammation by upregulating TGF-β1
Jia-Hau Yen, Ling-Chung Lin, Meng-Chi Chen, Zsolt Sarang, Pui-Ying Leong, I-Chang Chang, Jeng-Dong Hsu, Jiunn-Horng Chen, Yu-Fan Hsieh, Anna Pallai, Krisztina Köröskényi, Zsuzsa Szondy, Gregory J Tsay
Relative benefit-risk comparing diclofenac to other traditional non-steroidal anti-inflammatory drugs and cyclooxygenase-2 inhibitors in patients with osteoarthritis or rheumatoid arthritis: a network meta-analysis
Anneloes van Walsem, Shaloo Pandhi, Richard M Nixon, Patricia Guyot, Andreas Karabis, R Andrew Moore
Meta-analysis of two Chinese populations identifies an autoimmune disease risk allele in 22q11.21 as associated with systemic lupus erythematosus
Yan Zhang, Yong-Fei Wang, Jing Yang, Jing Zhang, Liangdan Sun, Nattiya Hirankarn, Hai-Feng Pan, Chak Sing Lau, Tak Mao Chan, Tsz Leung Lee, Alexander Moon Ho Leung, Chi Chiu Mok, Lu Zhang, Jiangshan Jane Shen, Sik Nin Wong, Ka Wing Lee, Marco Hok Kung Ho, Pamela Pui Wah Lee, Brian Hon-Yin Chung, Chun Yin Chong, Raymond Woon Sing Wong, Mo Yin Mok, Wilfred Hing Sang Wong, Kwok Lung Tong, Niko Kei Chiu Tse, Xiang-Pei Li, Yingyos Avihingsanon, Pornpimol Rianthavorn, Thavatchai Deekajorndej, Kanya Suphapeetiporn, Vorasuk Shotelersuk, Shirley King Yee Ying, Samuel Ka Shun Fung, Wai Ming Lai, Chun-Ming Wong, Irene Oi Lin Ng, Maria-Merce Garcia-Barcelo, Stacey S Cherny, Paul Kwong-Hang Tam, Pak Chung Sham, Sen Yang, Dong Qing Ye, Yong Cui, Xue-Jun Zhang, Wanling Yang, Yu Lung Lau
Intracellular free radical production by peripheral blood T lymphocytes from patients with systemic sclerosis: role of NADPH oxidase and ERK1/2
Donatella Amico, Tatiana Spadoni, Marina Rovinelli, Marta Serafini, Giovanna D’Amico, Nadia Campelli, Silvia Svegliati Baroni, Armando Gabrielli
Detecting cathepsin activity in human osteoarthritis via activity-based probes
Louisa Ben-Aderet, Emmanuelle Merquiol, Duha Fahham, Ashok Kumar, Eli Reich, Yael Ben-Nun, Leonid Kandel, Amir Haze, Meir Liebergall, Marta K Kosińska, Juergen Steinmeyer, Boris Turk, Galia Blum, Mona Dvir-Ginzberg
Racial disparities in total ankle arthroplasty utilization and outcomes
Jasvinder A Singh, Rekha Ramachandran
Identification of NF-κB and PLCL2 as new susceptibility genes and highlights on a potential role of IRF8 through interferon signature modulation in systemic sclerosis
Maria Arismendi, Matthieu Giraud, Nadira Ruzehaji, Philippe Dieudé, Eugenie Koumakis, Barbara Ruiz, Paolo Airo, Daniele Cusi, Marco Matucci-Cerinic, Erika Salvi, Giovanna Cuomo, Eric Hachulla, Elisabeth Diot, Paola Caramaschi, Valeria Riccieri, Jérôme Avouac, Cristiane Kayser, Yannick Allanore
Local synthesis of interferon-alpha in lupus nephritis is associated with type I interferons signature and LMP7 induction in renal tubular epithelial cells
Giuseppe Castellano, Cesira Cafiero, Chiara Divella, Fabio Sallustio, Margherita Gigante, Paola Pontrelli, Giuseppe De Palma, Michele Rossini, Giuseppe Grandaliano, Loreto Gesualdo
Multiplex cytokine analysis of dermal interstitial blister fluid defines local disease mechanisms in systemic sclerosis
Kristina EN Clark, Henry Lopez, Bahja Ahmed Abdi, Sandra G Guerra, Xu Shiwen, Korsa Khan, Oseme Etomi, George R Martin, David J Abraham, Christopher P Denton, Richard J Stratton
Head-to-head comparison of the safety of tocilizumab and tumor necrosis factor inhibitors in rheumatoid arthritis patients (RA) in clinical practice: results from the registry of Japanese RA patients on biologics for long-term safety (REAL) registry
Ryoko Sakai, Soo-Kyung Cho, Toshihiro Nanki, Kaori Watanabe, Hayato Yamazaki, Michi Tanaka, Ryuji Koike, Yoshiya Tanaka, Kazuyoshi Saito, Shintaro Hirata, Koichi Amano, Hayato Nagasawa, Takayuki Sumida, Taichi Hayashi, Takahiko Sugihara, Hiroaki Dobashi, Shinsuke Yasuda, Tetsuji Sawada, Kazuhiko Ezawa, Atsuhisa Ueda, Takao Fujii, Kiyoshi Migita, Nobuyuki Miyasaka, Masayoshi Harigai
Cumulative inflammatory burden is independently associated with increased arterial stiffness in patients with psoriatic arthritis: a prospective study
Jiayun Shen, Qing Shang, Edmund K Li, Ying-Ying Leung, Emily W Kun, Lai-Wa Kwok, Martin Li, Tena K Li, Tracy Y Zhu, Cheuk-Man Yu, Lai-Shan Tam
CD4 T-cell transcriptome analysis reveals aberrant regulation of STAT3 and Wnt signaling pathways in rheumatoid arthritis: evidence from a case–control study
Hua Ye, Jing Zhang, Jun Wang, Yanyan Gao, Yan Du, Chun Li, Minghua Deng, Jianping Guo, Zhanguo Li
Application of the 2013 ACR/EULAR classification criteria for systemic sclerosis to patients with Raynaud’s phenomenon
Jin-Su Park, Min-Chan Park, Jason Jungsik Song, Yong-Beom Park, Soo-Kon Lee, Sang-Won Lee
Effect of prednisone on type I interferon signature in rheumatoid arthritis: consequences for response prediction to rituximab
Tamarah D de Jong, Saskia Vosslamber, Marjolein Blits, Gertjan Wolbink, Mike T Nurmohamed, Conny J van der Laken, Gerrit Jansen, Alexandre E Voskuyl, Cornelis L Verweij
Visceral fat obesity is highly associated with primary gout in a metabolically obese but normal weighted population: a case control study
Jennifer Lee, Ji-Yeon Lee, Jae-Ho Lee, Seung-Min Jung, Young Sun Suh, Jung-Hee Koh, Seung-Ki Kwok, Ji Hyeon Ju, Kyung-Su Park, Sung-Hwan Park
Results of a proof of concept, double-blind, randomized trial of a second generation antisense oligonucleotide targeting high-sensitivity C-reactive protein (hs-CRP) in rheumatoid arthritis
Marshelle S Warren, Steven G Hughes, Walter Singleton, Mason Yamashita, Mark C Genovese
Characterization of the major histocompatibility complex locus association with Behçet’s disease in Iran
Joana M Xavier, Fereydoun Davatchi, Olga Abade, Farhad Shahram, Vânia Francisco, Bahar Sadeghi Abdollahi, Hélder Trindade, Abdolhadi Nadji, Niloofar Mojarad Shafiee, Fahmida Ghaderibarmi, Dário Ligeiro, Sofia A Oliveira
Meniscal extrusion promotes knee osteoarthritis structural progression: protective effect of strontium ranelate treatment in a phase III clinical trial
Camille Roubille, Johanne Martel-Pelletier, Jean-Pierre Raynauld, François Abram, Marc Dorais, Philippe Delorme, Jean-Pierre Pelletier
An external validation study reporting poor correlation between the claims-based index for rheumatoid arthritis severity and the disease activity score
Rishi J Desai, Daniel H Solomon, Michael E Weinblatt, Nancy Shadick, Seoyoung C Kim
Bone mineral density and carotid atherosclerosis in systemic lupus erythematosus: a controlled cross-sectional study
Sofia Ajeganova, Thomas Gustafsson, Tomas Jogestrand, Johan Frostegård, Ingiäld Hafström
Association analyses confirm five susceptibility loci for systemic lupus erythematosus in the Han Chinese population
Yu-jun Sheng, Jian-hua Xu, Yong-gui Wu, Xian-bo Zuo, Jin-ping Gao, Yan Lin, Zheng-wei Zhu, Lei-lei Wen, Chao Yang, Lu Liu, Yu-yan Cheng, Yan Chang, Lu-lu Yang, Fu-sheng Zhou, Xian-fa Tang, Xiao-dong Zheng, Xian-yong Yin, Hua-yang Tang, Liang-dan Sun, Yong Cui, Sen Yang, Xue-jun Zhang
Body mass index and the risk of rheumatoid arthritis: a systematic review and dose-response meta-analysis
Baodong Qin, Min Yang, Haitao Fu, Ning Ma, Tingting Wei, Qingqin Tang, Zhide Hu, Yan Liang, Zaixing Yang, Renqian Zhong
The interface between cholinergic pathways and the immune system and its relevance to arthritis
Robin M McAllen, Andrew D Cook, Hsu Wei Khiew, Davide Martelli, John A Hamilton
Methotrexate: should it still be considered for chronic calcium pyrophosphate crystal disease?
Eliseo Pascual, Mariano Andrés, Francisca Sivera
Gout and risk of chronic kidney disease and nephrolithiasis: meta-analysis of observational studies
Matthew J Roughley, John Belcher, Christian D Mallen, Edward Roddy
The involvement of follistatin-like protein 1 in osteoarthritis by elevating NF-κB-mediated inflammatory cytokines and enhancing fibroblast like synoviocyte proliferation
Su Ni, Kaisong Miao, Xianju Zhou, Nanwei Xu, Chenkai Li, Ruixia Zhu, Rongbin Sun, Yuji Wang
Differential effects of cyclophosphamide and mycophenolate mofetil on cellular and serological parameters in patients with systemic lupus erythematosus
Till Fassbinder, Ute Saunders, Eva Mickholz, Elisabeth Jung, Heidemarie Becker, Bernhard Schlüter, Annett Marita Jacobi
The novel S59P mutation in the TNFRSF1A gene identified in an adult onset TNF receptor associated periodic syndrome (TRAPS) constitutively activates NF-κB pathway
Eliana Greco, Ada Aita, Paola Galozzi, Alessandra Gava, Paolo Sfriso, Ola H Negm, Patrick Tighe, Francesco Caso, Filippo Navaglia, Emanuela Dazzo, Marzia De Bortoli, Alessandra Rampazzo, Laura Obici, Simona Donadei, Giampaolo Merlini, Mario Plebani, Ian Todd, Daniela Basso, Leonardo Punzi
The cellular signature of urinary immune cells in Lupus nephritis: new insights into potential biomarkers
Katharina Kopetschke, Jan Klocke, Anna-Sophie Grießbach, Jens Y Humrich, Robert Biesen, Duska Dragun, Gerd-Rüdiger Burmester, Philipp Enghard, Gabriela Riemekasten
Evaluation of the effect of tofacitinib on measured glomerular filtration rate in patients with active rheumatoid arthritis: results from a randomised controlled trial
Joel M Kremer, Alan J Kivitz, Jesus A Simon-Campos, Evgeny L Nasonov, Hans-Peter Tony, Soo-Kon Lee, Bonnie Vlahos, Constance Hammond, Jack Bukowski, Huihua Li, Seth L Schulman, Susan Raber, Andrea Zuckerman, John D Isaacs
Response to ‘Increase of nerve growth factor levels in the human herniated intervertebral disc: can annular rupture trigger discogenic back pain?’ – authors’ reply
Yasuchika Aoki, Arata Nakajima, Seiji Ohtori, Hiroshi Takahashi, Fusako Watanabe, Masato Sonobe, Fumiaki Terajima, Masahiko Saito, Kazuhisa Takahashi, Tomoaki Toyone, Atsuya Watanabe, Takayuki Nakajima, Makoto Takazawa, Koichi Nakagawa
Patients lacking classical poor prognostic markers might also benefit from a step-down glucocorticoid bridging scheme in early rheumatoid arthritis: week 16 results from the randomized multicenter CareRA trial
Patrick Verschueren, Diederik De Cock, Luk Corluy, Rik Joos, Christine Langenaken, Veerle Taelman, Frank Raeman, Isabelle Ravelingien, Klaas Vandevyvere, Jan Lenaerts, Elke Geens, Piet Geusens, Johan Vanhoof, Anne Durnez, Jan Remans, Bert Vander Cruyssen, Els Van Essche, An Sileghem, Griet De Brabanter, Johan Joly, Kristien Van der Elst, Sabrina Meyfroidt, Rene Westhovens
Subclinical atherosclerosis and impaired bone health in patients with primary Sjogren’s syndrome: prevalence, clinical and laboratory associations
Fotini Gravani, Ioanna Papadaki, Eleni Antypa, Andrianos Nezos, Kyriaki Masselou, Dimitrios Ioakeimidis, Michael Koutsilieris, Haralampos M Moutsopoulos, Clio P Mavragani
Glucose-6-phosphate isomerase promotes the proliferation and inhibits the apoptosis in fibroblast-like synoviocytes in rheumatoid arthritis
Ming Zong, Tianbao Lu, Shasha Fan, Hui Zhang, Ruhan Gong, Lishan Sun, Zhiyan Fu, Lieying Fan
Fetal microchimerism in kidney biopsies of lupus nephritis patients may be associated with a beneficial effect
Greiciane MS Florim, Heloisa C Caldas, Julio CR de Melo, Maria Alice SF Baptista, Ida MM Fernandes, Marcela Savoldi-Barbosa, Gustavo H Goldman, Mario Abbud-Filho
Association of HLA-B*41:02 with Henoch-Schönlein Purpura (IgA Vasculitis) in Spanish individuals irrespective of the HLA-DRB1 status
Raquel López-Mejías, Fernanda Genre, Belén Sevilla Pérez, Santos Castañeda, Norberto Ortego-Centeno, Javier Llorca, Begoña Ubilla, Sara Remuzgo-Martínez, Verónica Mijares, Trinitario Pina, Vanesa Calvo-Río, Ana Márquez, José A Miranda-Filloy, Antonio Navas Parejo, Marta Conde-Jaldón, Lourdes Ortiz-Fernández, Diego Argila, Maximiliano Aragües, Esteban Rubio, Manuel León Luque, Juan María Blanco-Madrigal, Eva Galíndez-Aguirregoikoa, Francisca González Escribano, J Gonzalo Ocejo-Vinyals, Javier Martín, Ricardo Blanco, Miguel A González-Gay
Enhanced activation of dendritic cells by autologous apoptotic microvesicles in MRL/lpr mice
Jürgen Dieker, Luuk Hilbrands, Astrid Thielen, Henry Dijkman, Jo H Berden, Johan van der Vlag
Anti-citrullinated peptide/protein antibody (ACPA)-negative RA shares a large proportion of susceptibility loci with ACPA-positive RA: a meta-analysis of genome-wide association study in a Japanese population
Chikashi Terao, Koichiro Ohmura, Yuta Kochi, Katsunori Ikari, Yukinori Okada, Masakazu Shimizu, Naoshi Nishina, Akari Suzuki, Keiko Myouzen, Takahisa Kawaguchi, Meiko Takahashi, Kiyoshi Takasugi, Akira Murasawa, Shinichi Mizuki, Mitsuhiro Iwahashi, Keiko Funahashi, Masamitsu Natsumeda, Moritoshi Furu, Motomu Hashimoto, Hiromu Ito, Takao Fujii, Kazuhiko Ezawa, Tsukasa Matsubara, Tsutomu Takeuchi, Michiaki Kubo, Ryo Yamada, Atsuo Taniguchi, Hisashi Yamanaka, Shigeki Momohara, Kazuhiko Yamamoto, Tsuneyo Mimori, Fumihiko Matsuda
Involvement of RORγt-overexpressing T cells in the development of autoimmune arthritis in mice
Yuya Kondo, Zhaojin Yao, Masahiro Tahara, Mana Iizuka, Masahiro Yokosawa, Shunta Kaneko, Seiji Segawa, Hiroto Tsuboi, Keigyou Yoh, Satoru Takahashi, Isao Matsumoto, Takayuki Sumida
Response to ‘Increase of nerve growth factor levels in the human herniated intervertebral disc: can annular rupture trigger discogenic back pain?’
Mehmet Agilli, Safak Ekinci
Early cartilage abnormalities at the hip are associated with obesity and body composition measures – a 3.0T MRI community-based study
Andrew J Teichtahl, Yuanyuan Wang, Sam Smith, Anita E Wluka, Donna Urquhart, Graham G Giles, Sultana Monira Hussain, Flavia M Cicuttini
Reappraisal of the diagnostic and prognostic value of morning stiffness in arthralgia and early arthritis: results from the Groningen EARC, Leiden EARC, ESPOIR, Leiden EAC and REACH
Jessica AB van Nies, Celina Alves, Audrey LS Radix-Bloemen, Cécile Gaujoux-Viala, Tom WJ Huizinga, Johanna MW Hazes, Elisabeth Brouwer, Bruno Fautrel, Annette HM van der Helm-van Mil
Histological antiphospholipid-associated nephropathy versus lupus nephritis in patients with systemic lupus erythematosus: an observational cross-sectional study with longitudinal follow-up
Jakob Gerhardsson, Birgitta Sundelin, Agneta Zickert, Leonid Padyukov, Elisabet Svenungsson, Iva Gunnarsson
Comparison and evaluation of lupus nephritis response criteria in lupus activity indices and clinical trials
Kristin M Corapi, Mary Anne Dooley, William F Pendergraft III
Response to ‘Interspinous bursitis is common in polymyalgia rheumatica, but is not associated with spinal pain’
Peter A Simkin
Bone geometry of the hip is associated with obesity and early structural damage – a 3.0 T magnetic resonance imaging study of community-based adults
Andrew J Teichtahl, Yuanyuan Wang, Sam Smith, Anita E Wluka, Michael Zhu, Donna Urquhart, Graham G Giles, Richard O’Sullivan, Flavia M Cicuttini
Are mesenchymal stem cells in rheumatoid arthritis the good or bad guys?
Cosimo De Bari
Physical inactivity is associated with narrower lumbar intervertebral discs, high fat content of paraspinal muscles and low back pain and disability
Andrew J Teichtahl, Donna M Urquhart, Yuanyuan Wang, Anita E Wluka, Richard O’Sullivan, Graeme Jones, Flavia M Cicuttini
Concepts of pathogenesis in psoriatic arthritis: genotype determines clinical phenotype
Oliver FitzGerald, Muhammad Haroon, Jon T Giles, Robert Winchester
Utility of a novel inflammatory marker, GlycA, for assessment of rheumatoid arthritis disease activity and coronary atherosclerosis
Michelle J. Ormseth, Cecilia P. Chung, Annette M. Oeser, Margery A. Connelly, Tuulikki Sokka, Paolo Raggi, Joseph F. Solus, James D. Otvos, C. Michael Stein
The prevalence of clinically diagnosed ankylosing spondylitis and its clinical manifestations: a nationwide register study
Sofia Exarchou, Ulf Lindström, Johan Askling, Jonas K Eriksson, Helena Forsblad-d’Elia, Martin Neovius, Carl Turesson, Lars Erik Kristensen, Lennart TH Jacobsson
Activating enhancer binding protein 2 epsilon (AP-2ε)-deficient mice exhibit increased matrix metalloproteinase 13 expression and progressive osteoarthritis development
Stephan Niebler, Thomas Schubert, Ernst B Hunziker, Anja K Bosserhoff
Comparative effectiveness of urate lowering with febuxostat versus allopurinol in gout: analyses from large U.S. managed care cohort
Jasvinder A Singh, Kasem S Akhras, Aki Shiozawa
Differential glucocorticoid metabolism in patients with persistent versus resolving inflammatory arthritis
Dominika E Nanus, Andrew D Filer, Lorraine Yeo, Dagmar Scheel-Toellner, Rowan Hardy, Gareth G Lavery, Paul M Stewart, Christopher D Buckley, Jeremy W Tomlinson, Mark S Cooper, Karim Raza
Pattern recognition receptors as potential therapeutic targets in inflammatory rheumatic disease
Lisa M Mullen, Giselle Chamberlain, Sandra Sacre
Borderline pulmonary pressures in scleroderma - a ‘pre-pulmonary arterial hypertension’ condition?
Gabor Kovacs, Horst Olschewski
The association between antibody levels before and after 7-valent pneumococcal conjugate vaccine immunization and subsequent pneumococcal infection in chronic arthritis patients
Johanna Nagel, Pierre Geborek, Tore Saxne, Göran Jönsson, Martin Englund, Ingemar F Petersson, Jan-Åke Nilsson, Lennart Truedsson, Meliha C Kapetanovic
Associations of antibodies against citrullinated peptides with human leukocyte antigen-shared epitope and smoking prior to the development of rheumatoid arthritis
Heidi Kokkonen, Mikael Brink, Monika Hansson, Ewa Lassen, Linda Mathsson-Alm, Rikard Holmdahl, Johan Rönnelid, Lars Klareskog, Solbritt Rantapää-Dahlqvist
Evidence for cadherin-11 cleavage in the synovium and partial characterization of its mechanism
Erika H Noss, Gerald FM Watts, Davide Zocco, Tracy L Keller, Malcolm Whitman, Carl P Blobel, David M Lee, Michael B Brenner
Mass cytometry as a platform for the discovery of cellular biomarkers to guide effective rheumatic disease therapy
Nitya Nair, Henrik E Mei, Shih-Yu Chen, Matthew Hale, Garry P Nolan, Holden T Maecker, Mark Genovese, C Garrison Fathman, Chan C Whiting
A candidate gene study reveals association between a variant of the Peroxisome Proliferator-Activated Receptor Gamma (PPAR-γ) gene and systemic sclerosis
Roberta Goncalves Marangoni, Benjamin D Korman, Yannick Allanore, Philippe Dieude, Loren L Armstrong, Margarita Rzhetskaya, Monique Hinchcliff, Mary Carns, Sofia Podlusky, Sanjiv J Shah, Barbara Ruiz, Eric Hachulla, Kiet Tiev, Jean-Luc Cracowski, John Varga, M Geoffrey Hayes
Plasma complement factor H is associated with disease activity of patients with ANCA-associated vasculitis
Su-Fang Chen, Feng-Mei Wang, Zhi-Ying Li, Feng Yu, Ming-Hui Zhao, Min Chen
Association of large intergenic noncoding RNA expression with disease activity and organ damage in systemic lupus erythematosus
Yanfang Wu, Feifei Zhang, Jianyang Ma, Xiaoyan Zhang, Lingling Wu, Bo Qu, Shiwei Xia, Shunle Chen, Yuanjia Tang, Nan Shen
Longitudinal analysis of peripheral blood T cell receptor diversity in patients with systemic lupus erythematosus by next-generation sequencing
Dharma R Thapa, Raffi Tonikian, Chao Sun, Mei Liu, Andrea Dearth, Michelle Petri, Francois Pepin, Ryan O Emerson, Ann Ranger
Existing joint erosions increase the risk of joint space narrowing independently of clinical synovitis in patients with early rheumatoid arthritis
Robert Landewé, Josef S Smolen, Stefan Florentinus, Su Chen, Benoît Guérette, Désirée van der Heijde
Cost-effectiveness of abatacept, rituximab, and TNFi treatment after previous failure with TNFi treatment in rheumatoid arthritis: a pragmatic multi-centre randomised trial
Sofie HM Manders, Wietske Kievit, Eddy Adang, Herman L Brus, Hein J Bernelot Moens, Andre Hartkamp, Lidy Hendriks, Elisabeth Brouwer, Henk Visser, Harald E Vonkeman, Jos Hendrikx, Tim L Jansen, Rene Westhovens, Mart AFJ van de Laar, Piet LCM van Riel
The preclinical pharmacology of the high affinity anti-IL-6R Nanobody® ALX-0061 supports its clinical development in rheumatoid arthritis
Maarten Van Roy, Cedric Ververken, Els Beirnaert, Sven Hoefman, Joost Kolkman, Michel Vierboom, Elia Breedveld, Bert ‘t Hart, Sofie Poelmans, Lieselot Bontinck, Alex Hemeryck, Sandy Jacobs, Judith Baumeister, Hans Ulrichts
Safety of biologic and nonbiologic disease-modifying antirheumatic drug therapy in veterans with rheumatoid arthritis and hepatitis B virus infection: a retrospective cohort study
Mary Jane Burton, Jeffrey R Curtis, Shuo Yang, Lang Chen, Jasvinder A Singh, Ted R Mikuls, Kevin L Winthrop, John W Baddley
Intradiscal application of rhBMP-7 does not induce regeneration in a canine model of spontaneous intervertebral disc degeneration
Nicole Willems, Frances C Bach, Saskia G M Plomp, Mattie HP van Rijen, Jeannette Wolfswinkel, Guy CM Grinwis, Clemens Bos, Gustav J Strijkers, Wouter JA Dhert, Björn P Meij, Laura B Creemers, Marianna A Tryfonidou
Linking classification and therapeutic management of vasculitides
Corisande Baldwin, Simon Carette, Christian Pagnoux
Gout and the risk of dementia: a nationwide population-based cohort study
Jen-Yee Hong, Tzuo-Yun Lan, Gau-Jun Tang, Chao-Hsiun Tang, Tzeng-Ji Chen, Hsiao-Yi Lin
KIAA1199 as a potential diagnostic biomarker of rheumatoid arthritis related to angiogenesis
Xinyu Yang, Pengcheng Qiu, Bingbing Chen, Yaoyao Lin, Zhonghao Zhou, Renshan Ge, Hai Zou, Jianmin Wang, Jianguang Wang
Early biomarkers of joint damage in rheumatoid and psoriatic arthritis
Angela Mc Ardle, Brian Flatley, Stephen R. Pennington, Oliver FitzGerald
Eicosapentaenoic acid and docosapentaenoic acid monoglycerides are more potent than docosahexaenoic acid monoglyceride to resolve inflammation in a rheumatoid arthritis model
Caroline Morin, Pierre U Blier, Samuel Fortin
Approaches for estimating minimal clinically important differences in systemic lupus erythematosus
Sharan K Rai, Jinoos Yazdany, Paul R Fortin, J Antonio Aviña-Zubieta
Laminin-rich blood vessels display activated growth factor signaling and act as the proliferation centers in Dupuytren’s contracture
Janeli Viil, Katre Maasalu, Kristina Mäemets-Allas, Liis Tamming, Kadi Lõhmussaar, Mikk Tooming, Sulev Ingerpuu, Aare Märtson, Viljar Jaks
RETRACTED ARTICLE: Combined effect of genetic background and gender in a mouse model of bleomycin-induced skin fibrosis
Nadira Ruzehaji, Jerome Avouac, Muriel Elhai, Maxime Frechet, Camelia Frantz, Barbara Ruiz, Joerg H. Distler, Yannick Allanore
Salivary gland ultrasonography: a highly specific tool for the early diagnosis of primary Sjögren’s syndrome
Chiara Baldini, Nicoletta Luciano, Gaia Tarantini, Rachele Pascale, Francesca Sernissi, Marta Mosca, Davide Caramella, Stefano Bombardieri
Yes-associated protein (YAP) is a negative regulator of chondrogenesis in mesenchymal stem cells
Alexandra Karystinou, Anke J Roelofs, Anna Neve, Francesco P Cantatore, Henning Wackerhage, Cosimo De Bari
Cervical spine involvement in rheumatoid arthritis over time: results from a meta-analysis
Tony Zhang, Janet Pope
Pneumococcal polysaccharide vaccination in rheumatoid arthritis patients receiving tacrolimus
Kiyoshi Migita, Yukihiro Akeda, Manabu Akazawa, Shigeto Tohma, Fuminori Hirano, Haruko Ideguchi, Ryutaro Matsumura, Eiichi Suematsu, Tomoya Miyamura, Shunsuke Mori, Takahiro Fukui, Yasumori Izumi, Nozomi Iwanaga, Hiroshi Tsutani, Kouichirou Saisyo, Takao Yamanaka, Shiro Ohshima, Takao Sugiyama, Yojiro Kawabe, Masao Katayama, Yasuo Suenaga, Akira Okamoto, Hisaji Ohshima, Yasumasa Okada, Kenji Ichikawa, Shigeru Yoshizawa, Kenji Kawakami, Toshihiro Matsui, Hiroshi Furukawa, Kazunori Oishi
Transvenous vagus nerve stimulation does not modulate the innate immune response during experimental human endotoxemia: a randomized controlled study
Matthijs Kox, Lucas T. van Eijk, Tim Verhaak, Tim Frenzel, Harmke D. Kiers, Jelle Gerretsen, Johannes G. van der Hoeven, Lilian Kornet, Avram Scheiner, Peter Pickkers
Pneumococcal polysaccharide vaccination in adults undergoing immunosuppressive treatment for inflammatory diseases – a longitudinal study
Lara Fischer, Patricia Francis Gerstel, Antoine Poncet, Claire-Anne Siegrist, Emmanuel Laffitte, Cem Gabay, Joerg Dieter Seebach, Camillo Ribi
Prognostic factors for progression of clinical osteoarthritis of the knee: a systematic review of observational studies
Alex N. Bastick, Jos Runhaar, Janneke N. Belo, Sita M.A. Bierma-Zeinstra
Toll-like receptor 2 (TLR2) induces migration and invasive mechanisms in rheumatoid arthritis
Trudy McGarry, Douglas J. Veale, Wei Gao, Carl Orr, Ursula Fearon, Mary Connolly
Overexpression of microRNA-155 increases IL-21 mediated STAT3 signaling and IL-21 production in systemic lupus erythematosus
Tue Kruse Rasmussen, Thomas Andersen, Rasmus Otkjær Bak, Gloria Yiu, Christian Møller Sørensen, Kristian Stengaard-Pedersen, Jacob Giehm Mikkelsen, Paul Joseph Utz, Christian Kanstrup Holm, Bent Deleuran
Targeting of anti-citrullinated protein/peptide antibodies in rheumatoid arthritis using peptides mimicking endogenously citrullinated fibrinogen antigens
Cátia Fernandes-Cerqueira, Elena Ossipova, Sunithi Gunasekera, Monika Hansson, Linda Mathsson, Anca I. Catrina, Yngve Sommarin, Lars Klareskog, Karin Lundberg, Johan Rönnelid, Ulf Göransson, Per-Johan Jakobsson
Comparison of two different folic acid doses with methotrexate – a randomized controlled trial (FOLVARI Study)
Varun Dhir, Amit Sandhu, Jasbinder Kaur, Benzeeta Pinto, Phani Kumar, Prabhdeep Kaur, Nidhi Gupta, Ankita Sood, Aman Sharma, Shefali Sharma
Attainment and characteristics of clinical remission according to the new ACR-EULAR criteria in abatacept-treated patients with early rheumatoid arthritis: new analyses from the Abatacept study to Gauge Remission and joint damage progression in methotrexate (MTX)-naive patients with Early Erosive rheumatoid arthritis (AGREE)
Josef S. Smolen, Jürgen Wollenhaupt, Juan J. Gomez-Reino, Walter Grassi, Corine Gaillez, Coralie Poncet, Manuela Le Bars, Rene Westhovens
High mobility group box 1 levels in large vessel vasculitis are not associated with disease activity but are influenced by age and statins
Alexandre W. S. de Souza, Kornelis S. M. van der Geest, Elisabeth Brouwer, Frederico A. G. Pinheiro, Ana Cecília Diniz Oliveira, Emília Inoue Sato, Luis Eduardo C. Andrade, Marc Bijl, Johanna Westra, Cees G. M. Kallenberg
Gene expression changes reflect clinical response in a placebo-controlled randomized trial of abatacept in patients with diffuse cutaneous systemic sclerosis
Eliza F. Chakravarty, Viktor Martyanov, David Fiorentino, Tammara A. Wood, David James Haddon, Justin Ansel Jarrell, Paul J. Utz, Mark C. Genovese, Michael L. Whitfield, Lorinda Chung
DNA methylation regulates sclerostin (SOST) expression in osteoarthritic chondrocytes by bone morphogenetic protein 2 (BMP-2) induced changes in Smads binding affinity to the CpG region of SOST promoter
Ioanna Papathanasiou, Fotini Kostopoulou, Konstantinos N. Malizos, Aspasia Tsezou
Resistance exercise improves muscle strength, health status and pain intensity in fibromyalgia—a randomized controlled trial
Anette Larsson, Annie Palstam, Monika Löfgren, Malin Ernberg, Jan Bjersing, Indre Bileviciute-Ljungar, Björn Gerdle, Eva Kosek, Kaisa Mannerkorpi
Autoantigen microarrays reveal autoantibodies associated with proliferative nephritis and active disease in pediatric systemic lupus erythematosus
D. James Haddon, Vivian K. Diep, Jordan V. Price, Cindy Limb, Paul J. Utz, Imelda Balboni
Complementary action of granulocyte macrophage colony-stimulating factor and interleukin-17A induces interleukin-23, receptor activator of nuclear factor-κB ligand, and matrix metalloproteinases and drives bone and cartilage pathology in experimental arthritis: rationale for combination therapy in rheumatoid arthritis
Annemarie E. M. van Nieuwenhuijze, Fons A. van de Loo, Birgitte Walgreen, Miranda Bennink, Monique Helsen, Liduine van den Bersselaar, Ian P. Wicks, Wim B. van den Berg, Marije I. Koenders
Organisation of the motor cortex differs between people with and without knee osteoarthritis
Camille J. Shanahan, Paul W. Hodges, Tim V. Wrigley, Kim L. Bennell, Michael J. Farrell
Stress Doppler echocardiography for early detection of systemic sclerosis-associated pulmonary arterial hypertension
Christian Nagel, Philipp Henn, Nicola Ehlken, Antonello D’Andrea, Norbert Blank, Eduardo Bossone, Anke Böttger, Christoph Fiehn, Christine Fischer, Hanns-Martin Lorenz, Frank Stöckl, Ekkehard Grünig, Benjamin Egenlauf
Response to ‘Feasibility of tailored treatment based on risk stratification in patients with early rheumatoid arthritis’
Nathan Vastesaeger, Bruno Fautrel, Josef Smolen
Use of RNA sequencing to evaluate rheumatic disease patients
Eugenia G Giannopoulou, Olivier Elemento, Lionel B Ivashkiv
Improved serological detection of rheumatoid arthritis: a highly antigenic mimotope of carbonic anhydrase III selected in a murine model by phage display
Galber Rodrigues Araujo, Emília Rezende Vaz, Patricia Tiemi Fujimura, João Eurico Fonseca, Lucélia Maria de Lima, Helena Canhão, Gabriela Venturini, Karina Helena Morais Cardozo, Valdemir Melechco Carvalho, Marcelo Henrique Napimoga, Luiz Ricardo Goulart, João Gonçalves, Carlos Ueira-Vieira
Reactivity of rat bone marrow-derived macrophages to neurotransmitter stimulation in the context of collagen II-induced arthritis
Dominique Muschter, Claudia Göttl, Mandy Vogel, Joachim Grifka, Rainer H. Straub, Susanne Grässel
Cartilage in facet joints of patients with ankylosing spondylitis (AS) shows signs of cartilage degeneration rather than chondrocyte hypertrophy: implications for joint remodeling in AS
Janine Bleil, Joachim Sieper, Rene Maier, Uwe Schlichting, Axel Hempfing, Uta Syrbe, Heiner Appel
Response to ‘Feasibility of tailored treatment based on risk stratification in patients with early rheumatoid arthritis’ – authors’ reply
Iris M. Markusse, Willem F. Lems, Tom W.J. Huizinga, Cornelia F. Allaart
The clinical relevance of animal models in Sjögren’s syndrome: the interferon signature from mouse to man
Naomi I Maria, Petra Vogelsang, Marjan A Versnel
Ectopic lymphoid neogenesis is strongly associated with activation of the IL-23 pathway in rheumatoid synovitis
Juan D. Cañete, Raquel Celis, Nataliya Yeremenko, Raimon Sanmartí, Leonie van Duivenvoorde, Julio Ramírez, Iris Blijdorp, Carmen M. García-Herrero, José L. Pablos, Dominique L. Baeten
Rheumatoid arthritis–associated autoantibodies in non–rheumatoid arthritis patients with mucosal inflammation: a case–control study
Koen M J Janssen, Menke J de Smit, Elisabeth Brouwer, Fenne A C de Kok, Jan Kraan, Josje Altenburg, Marije K Verheul, Leendert A Trouw, Arie Jan van Winkelhoff, Arjan Vissink, Johanna Westra
Suppressed diversity of survivin splicing in active rheumatoid arthritis
Minna Turkkila, Karin M.E. Andersson, Sylvie Amu, Mikael Brisslert, Malin C. Erlandsson, Sofia Silfverswärd, Maria I. Bokarewa
Differences in glutamate receptors and inflammatory cell numbers are associated with the resolution of pain in human rotator cuff tendinopathy
Benjamin John Floyd Dean, Sarah J. B. Snelling, Stephanie G. Dakin, Richard J. Murphy, Muhammad Kassim Javaid, Andrew Jonathan Carr
Window of opportunity to achieve major outcomes in early rheumatoid arthritis patients: how persistence with therapy matters
Irazú Contreras-Yáñez, Virginia Pascual-Ramos
The epidemiology of symptomatic midfoot osteoarthritis in community-dwelling older adults: cross-sectional findings from the Clinical Assessment Study of the Foot
Martin J. Thomas, George Peat, Trishna Rathod, Michelle Marshall, Andrew Moore, Hylton B. Menz, Edward Roddy
In vivo pre-activation of monocytes in patients with axial spondyloarthritis
Kristina Conrad, Peihua Wu, Joachim Sieper, Uta Syrbe
Increased carotid artery intima-media thickness and myeloperoxidase level in children with newly diagnosed juvenile idiopathic arthritis
Jaanika Ilisson, Maksim Zagura, Kersti Zilmer, Erik Salum, Kaire Heilman, Anneli Piir, Vallo Tillmann, Jaak Kals, Mihkel Zilmer, Chris Pruunsild
Sustained biologic-free and drug-free remission in rheumatoid arthritis, where are we now?
György Nagy, Ronald F van Vollenhoven
Pathophysiology of cutaneous lupus erythematosus
Jordan C Achtman, Victoria P Werth
Measuring disease activity in adults with systemic lupus erythematosus: the challenges of administrative burden and responsiveness to patient concerns in clinical research
Jamal Mikdashi, Ola Nived
Association between arthritis score at the onset of the disease and long-term locomotor outcome in adjuvant-induced arthritis in rats
Claude Mossiat, Davy Laroche, Clément Prati, Thierry Pozzo, Céline Demougeot, Christine Marie
Epratuzumab inhibits the production of the proinflammatory cytokines IL-6 and TNF-α, but not the regulatory cytokine IL-10, by B cells from healthy donors and SLE patients
Vanessa Fleischer, Julia Sieber, Sarah J. Fleischer, Anthony Shock, Guido Heine, Capucine Daridon, Thomas Dörner
Clinicopathological characteristics of immunoglobulin G4-related sialadenitis
Wei Li, Yan Chen, Zhi-Peng Sun, Zhi-Gang Cai, Tong-Tong Li, Lei Zhang, Min-Xian Huang, Hong Hua, Mei Li, Xia Hong, Jia-Zeng Su, Zhu-Yan Zhang, Yan-Ying Liu, Jing He, Zhan-Guo Li, Yan Gao, Guang-Yan Yu
The role of interleukin-1 beta in the pathophysiology of Schnitzler’s syndrome
Heleen D. de Koning, Joost Schalkwijk, Monique Stoffels, Johanna Jongekrijg, Joannes F. M. Jacobs, Eugène Verwiel, Hans J. P. M. Koenen, Frank Preijers, Dirk Holzinger, Irma Joosten, Jos W. M. van der Meer, Anna Simon
A prospective evaluation of ultrasound as a diagnostic tool in acute microcrystalline arthritis
Pascal Zufferey, Roxana Valcov, Isabelle Fabreguet, Alexandre Dumusc, Patrick Omoumi, Alexander So
Trabecular bone loss in collagen antibody-induced arthritis
Louise Grahnemo, Annica Andersson, Merja Nurkkala-Karlsson, Alexandra Stubelius, Marie K. Lagerquist, Mattias N. D. Svensson, Claes Ohlsson, Hans Carlsten, Ulrika Islander
Autoregulatory function of interleukin-10-producing pre-naïve B cells is defective in systemic lupus erythematosus
Ji Hyun Sim, Hang-Rae Kim, Soog-Hee Chang, In Je Kim, Peter E. Lipsky, Jisoo Lee
The effects of joint aspiration and intra-articular corticosteroid injection on flexion reflex excitability, quadriceps strength and pain in individuals with knee synovitis: a prospective observational study
David Andrew Rice, Peter John McNair, Gwyn Nancy Lewis, Nicola Dalbeth
Blockade of bone morphogenetic protein signaling potentiates the pro-inflammatory phenotype induced by interleukin-17 and tumor necrosis factor-α combination in rheumatoid synoviocytes
Alberto Varas, Jaris Valencia, Fabien Lavocat, Víctor G. Martínez, Ndiémé Ndongo Thiam, Laura Hidalgo, Lidia M. Fernández-Sevilla, Rosa Sacedón, Angeles Vicente, Pierre Miossec
Osteoprotegerin and tumor necrosis factor-related apoptosis-inducing ligand as prognostic factors in rheumatoid arthritis: results from the ESPOIR cohort
Rachel Audo, Claire Daien, Laura Papon, Cédric Lukas, Olivier Vittecoq, Michael Hahne, Bernard Combe, Jacques Morel
Molecular characterization of systemic sclerosis esophageal pathology identifies inflammatory and proliferative signatures
Jaclyn N. Taroni, Viktor Martyanov, Chiang-Ching Huang, J. Matthew Mahoney, Ikuo Hirano, Brandon Shetuni, Guang-Yu Yang, Darren Brenner, Barbara Jung, Tammara A. Wood, Swati Bhattacharyya, Orit Almagor, Jungwha Lee, Arlene Sirajuddin, John Varga, Rowland W. Chang, Michael L. Whitfield, Monique Hinchcliff
Association of HLA-DRB1 amino acid residues with giant cell arteritis: genetic association study, meta-analysis and geo-epidemiological investigation
Sarah Louise Mackie, John C. Taylor, Lubna Haroon-Rashid, Stephen Martin, Bhaskar Dasgupta, Andrew Gough, Michael Green, Lesley Hordon, Stephen Jarrett, Colin T. Pease, Jennifer H. Barrett, Richard Watts, Ann W. Morgan
Transforming growth factor-β increases interleukin-13 synthesis via GATA-3 transcription factor in T-lymphocytes from patients with systemic sclerosis
Julie Baraut, Dominique Farge, Francette Jean-Louis, Ingrid Masse, Elena Ivan Grigore, Lucas C. M. Arruda, Jérôme Lamartine, Franck Verrecchia, Laurence Michel
Early medication use in new-onset rheumatoid arthritis may delay joint replacement: results of a large population-based study
Cristiano S. Moura, Michal Abrahamowicz, Marie-Eve Beauchamp, Diane Lacaille, Yishu Wang, Gilles Boire, Paul R. Fortin, Louis Bessette, Claire Bombardier, Jessica Widdifield, John G. Hanly, Debbie Feldman, Walter Maksymowych, Christine Peschken, Cheryl Barnabe, Steve Edworthy, Sasha Bernatsky
IL-17 sequestration via salivary gland gene therapy in a mouse model of Sjogren’s syndrome suppresses disease-associated expression of the putative autoantigen Klk1b22
Changgong Wu, Zhimin Wang, Lee Zourelias, Hiteshi Thakker, Michael J. Passineau
Peripheral blood derived mononuclear cells enhance osteoarthritic human chondrocyte migration
Niina Hopper, Frances Henson, Roger Brooks, Erden Ali, Neil Rushton, John Wardale
MRP8/14 serum levels as a predictor of response to starting and stopping anti-TNF treatment in juvenile idiopathic arthritis
Janneke Anink, Lisette W. A. Van Suijlekom-Smit, Marieke H. Otten, Femke H. M. Prince, Marion A. J. van Rossum, Koert M. Dolman, Esther P. A. H. Hoppenreijs, Rebecca ten Cate, Simona Ursu, Lucy R. Wedderburn, Gerd Horneff, Michael Frosch, Thomas Vogl, Faekah Gohar, Dirk Foell, Johannes Roth, Dirk Holzinger
Biomarkers of pulmonary hypertension in patients with scleroderma: a case–control study
Zsuzsanna McMahan, Florian Schoenhoff, Jennifer E. Van Eyk, Fredrick M. Wigley, Laura K. Hummers
Knowledge-based analysis of genetic associations of rheumatoid arthritis to inform studies searching for pleiotropic genes: a literature review and network analysis
Weiying Zheng, Shaoqi Rao
Physical function continues to improve when clinical remission is sustained in rheumatoid arthritis patients
Helga Radner, Farideh Alasti, Josef S. Smolen, Daniel Aletaha
The effects of experimental knee pain on lower limb corticospinal and motor cortex excitability
David Andrew Rice, Thomas Graven-Nielsen, Gwyn Nancy Lewis, Peter John McNair, Nicola Dalbeth
A subset of patients with systemic lupus erythematosus fails to degrade DNA from multiple clinically relevant sources
Jonatan Leffler, Katarzyna Ciacma, Birgitta Gullstrand, Anders A. Bengtsson, Myriam Martin, Anna M. Blom
Restrictive IgG antibody response against mutated citrullinated vimentin predicts response to rituximab in patients with rheumatoid arthritis
Luisa Lindenberg, Lydia Spengler, Holger Bang, Thomas Dorner, Aleksej L Maslyanskiy, Sergey V Lapin, Elena I Ilivanova, Lorena Martinez-Gamboa, Hans Bastian, Esther Wittenborn, Karl Egerer, Gerd-R Burmester, Eugen Feist
Wolff’s law in action: a mechanism for early knee osteoarthritis
Andrew J. Teichtahl, Anita E. Wluka, Pushpika Wijethilake, Yuanyuan Wang, Ali Ghasem-Zadeh, Flavia M. Cicuttini
Interferon gamma-inducible protein 16 in primary Sjögren’s syndrome: a novel player in disease pathogenesis?
Alessia Alunno, Valeria Caneparo, Francesco Carubbi, Onelia Bistoni, Sara Caterbi, Elena Bartoloni, Roberto Giacomelli, Marisa Gariglio, Santo Landolfo, Roberto Gerli
Anti-citrullinated protein antibodies contribute to platelet activation in rheumatoid arthritis
Kim L.L. Habets, Leendert A. Trouw, E.W. Nivine Levarht, Suzanne J.A. Korporaal, Petra A.M. Habets, Philip de Groot, Tom W.J. Huizinga, René E.M. Toes
Protein kinase C delta null mice exhibit structural alterations in articular surface, intra-articular and subchondral compartments
Xiaohong Yang, Dian Teguh, Jian-Ping Wu, Bo He, Thomas Brett Kirk, Shengnan Qin, Siming Li, Honghui Chen, Wei Xue, Benjamin Ng, Shek Man Chim, Jennifer Tickner, Jiake Xu
Vitamin D deficiency in chronic inflammatory rheumatic diseases: results of the cardiovascular in rheumatology [CARMA] study
Ana Urruticoechea-Arana, María A. Martín-Martínez, Santos Castañeda, Carlos A. Sanchez Piedra, Carlos González-Juanatey, Javier Llorca, Federico Díaz-Gonzalez, Miguel A. González-Gay
Incidence of malignancy in adult patients with rheumatoid arthritis: a meta-analysis
Teresa A. Simon, Adam Thompson, Kunal K. Gandhi, Marc C. Hochberg, Samy Suissa
Nilotinib (Tasigna™) in the treatment of early diffuse systemic sclerosis: an open-label, pilot clinical trial
Jessica K. Gordon, Viktor Martyanov, Cynthia Magro, Horatio F. Wildman, Tammara A. Wood, Wei-Ti Huang, Mary K. Crow, Michael L. Whitfield, Robert F. Spiera
Biocompatibility and intradiscal application of a thermoreversible celecoxib-loaded poly-N-isopropylacrylamide MgFe-layered double hydroxide hydrogel in a canine model
Nicole Willems, Hsiao-yin Yang, Marloes L. P. Langelaan, Anna R. Tellegen, Guy C. M. Grinwis, Hendrik-Jan C. Kranenburg, Frank M. Riemers, Saskia G. M. Plomp, Eric G. M. Craenmehr, Wouter J. A. Dhert, Nicole E. Papen-Botterhuis, Björn P. Meij, Laura B. Creemers, Marianna A. Tryfonidou
Treatment of systemic lupus erythematosus patients with the BAFF antagonist “peptibody” blisibimod (AMG 623/A-623): results from randomized, double-blind phase 1a and phase 1b trials
William Stohl, Joan T. Merrill, R. John Looney, Jill Buyon, Daniel J. Wallace, Michael H. Weisman, Ellen M. Ginzler, Blaire Cooke, Donna Holloway, Arunan Kaliyaperumal, Kameswara Rao Kuchimanchi, Tsui Chern Cheah, Erik Rasmussen, John Ferbas, Shelley S. Belouski, Wayne Tsuji, Debra J. Zack
Response to ‘Body mass index and the risk of rheumatoid arthritis: a systematic review and dose–response meta-analysis’
Yang Liu, Cheryl Barnabe
Response to: ‘Body mass index and the risk of rheumatoid arthritis: a systematic review and dose–response meta-analysis’ - authors’ reply
Baodong Qin, Yan Liang, Zaixing Yang, Renqian Zhong
Investigation of the relationship between the onset of arthritis and uveitis in genetically predisposed SKG mice
Ellen J. Lee, Emily E. Vance, Brieanna R. Brown, Paige S. Snow, Jenna S. Clowers, Shimon Sakaguchi, Holly L. Rosenzweig
Ten years of change in clinical disease status and treatment in rheumatoid arthritis: results based on standardized monitoring of patients in an ordinary outpatient clinic in southern Norway
Glenn Haugeberg, Inger Johanne Widding Hansen, Dag Magnar Soldal, Tuulikki Sokka
Abatacept decreases disease activity in the absence of CD4+ T cells in a collagen-induced arthritis model
Diahann TSL Jansen, Hanane el Bannoudi, Ramon Arens, Kim LL Habets, Marjolijn Hameetman, Tom WJ Huizinga, Jeroen N. Stoop, René EM Toes
Plexin-D1/Semaphorin 3E pathway may contribute to dysregulation of vascular tone control and defective angiogenesis in systemic sclerosis
Celestina Mazzotta, Eloisa Romano, Cosimo Bruni, Mirko Manetti, Gemma Lepri, Silvia Bellando-Randone, Jelena Blagojevic, Lidia Ibba-Manneschi, Marco Matucci-Cerinic, Serena Guiducci
Studies on ageing and the severity of radiographic joint damage in rheumatoid arthritis
Lukas Mangnus, Hanna W. van Steenbergen, Elisabet Lindqvist, Elisabeth Brouwer, Monique Reijnierse, Tom WJ Huizinga, Peter K. Gregersen, Ewa Berglin, Solbritt Rantapää-Dahlqvist, Désirée van der Heijde, Annette HM van der Helm-van Mil
Effectiveness of imaging modalities for screening IgG4-related dacryoadenitis and sialadenitis (Mikulicz’s disease) and for differentiating it from Sjögren’s syndrome (SS), with an emphasis on sonography
Mayumi Shimizu, Kazutoshi Okamura, Yoshitaka Kise, Yohei Takeshita, Hiroko Furuhashi, Warangkana Weerawanich, Masafumi Moriyama, Yukiko Ohyama, Sachiko Furukawa, Seiji Nakamura, Kazunori Yoshiura
A randomized, double-blind, placebo-controlled phase III trial of duloxetine in Japanese fibromyalgia patients
Masato Murakami, Kenichi Osada, Hiromichi Mizuno, Toshimitsu Ochiai, Levent Alev, Kusuki Nishioka
On the predictive utility of animal models of osteoarthritis
Anne-Marie Malfait, Christopher B. Little
Cannabinoid-based drugs targeting CB1 and TRPV1, the sympathetic nervous system, and arthritis
Torsten Lowin, Rainer H. Straub
Expression of Semaphorin 4A and its potential role in rheumatoid arthritis
Lin Wang, Guanhua Song, Yabing Zheng, Weiwei Tan, Jihong Pan, Yu Zhao, Xiaotian Chang
A systematic review of the relationship between subchondral bone features, pain and structural pathology in peripheral joint osteoarthritis
Andrew J. Barr, T. Mark Campbell, Devan Hopkinson, Sarah R. Kingsbury, Mike A. Bowes, Philip G. Conaghan
Rheumatoid factor, not antibodies against citrullinated proteins, is associated with baseline disease activity in rheumatoid arthritis clinical trials
Daniel Aletaha, Farideh Alasti, Josef S. Smolen
Phosphatase and tensin homolog (PTEN) in antigen-presenting cells controls Th17-mediated autoimmune arthritis
Stephan Blüml, Emine Sahin, Victoria Saferding, Eliana Goncalves-Alves, Eva Hainzl, Birgit Niederreiter, Anastasia Hladik, Tobias Lohmeyer, Julia S. Brunner, Michael Bonelli, Marije I. Koenders, Wim B. van den Berg, Giulio Superti-Furga, Josef S. Smolen, Gernot Schabbauer, Kurt Redlich
Associations between circulating endostatin levels and vascular organ damage in systemic sclerosis and mixed connective tissue disease: an observational study
Silje Reiseter, Øyvind Molberg, Ragnar Gunnarsson, May Brit Lund, Trond Mogens Aalokken, Pål Aukrust, Thor Ueland, Torhild Garen, Cathrine Brunborg, Annika Michelsen, Aurelija Abraityte, Anna-Maria Hoffmann-Vold
Disease flares in rheumatoid arthritis are associated with joint damage progression and disability: 10-year results from the BeSt study
Iris M. Markusse, Linda Dirven, Andreas H. Gerards, Johannes H L M van Groenendael, H. Karel Ronday, Pit J S M Kerstens, Willem F. Lems, Tom W J Huizinga, Cornelia F. Allaart
Assessment of global DNA methylation in peripheral blood cell subpopulations of early rheumatoid arthritis before and after methotrexate
María C. de Andres, Eva Perez-Pampin, Manuel Calaza, Francisco J. Santaclara, Ignacio Ortea, Juan J. Gomez-Reino, Antonio Gonzalez
CDP7657, an anti-CD40L antibody lacking an Fc domain, inhibits CD40L-dependent immune responses without thrombotic complications: an in vivo study
Anthony Shock, Linda Burkly, Ian Wakefield, Christopher Peters, Ellen Garber, Janine Ferrant, Frederick R. Taylor, Lihe Su, Yen-Ming Hsu, David Hutto, Ali Amirkhosravi, Todd Meyer, John Francis, Sarah Malcolm, Martyn Robinson, Derek Brown, Stevan Shaw, Roland Foulkes, Alastair Lawson, Olivier Harari, Timothy Bourne, Alison Maloney, Neil Weir
Joint production of IL-22 participates in the initial phase of antigen-induced arthritis through IL-1β production
Larissa G. Pinto, Jhimmy Talbot, Raphael S. Peres, Rafael F. Franca, Sérgio H. Ferreira, Bernhard Ryffel, José Carlos F. Aves-Filho, Florêncio Figueiredo, Thiago M. Cunha, Fernando Q. Cunha
Erratum to: Comparative effectiveness of urate lowering with febuxostat versus allopurinol in gout: analyses from large U.S. managed care cohort
Jasvinder A. Singh, Kasem S. Akhras, Aki Shiozawa
Neuropathic-like pain features and cross-sectional associations in rheumatoid arthritis
Sanne M. W. Koop, Peter M. ten Klooster, Harald E. Vonkeman, Laura M. M. Steunebrink, Mart A. F. J. van de Laar
Chimeric cells of maternal origin do not appear to be pathogenic in the juvenile idiopathic inflammatory myopathies or muscular dystrophy
Carol M. Artlett, Sihem Sassi-Gaha, Ronald C. Ramos, Frederick W. Miller, Lisa G. Rider
Serum RANKL levels associate with anti- citrullinated protein antibodies in early untreated rheumatoid arthritis and are modulated following methotrexate
Aase Haj Hensvold, Vijay Joshua, Wanying Li, Michaela Larkin, Ferhan Qureshi, Lena Israelsson, Leonid Padyukov, Karin Lundberg, Nadine Defranoux, Saedis Saevarsdottir, Anca Irinel Catrina
The biological basis of degenerative disc disease: proteomic and biomechanical analysis of the canine intervertebral disc
William Mark Erwin, Leroi DeSouza, Martha Funabashi, Greg Kawchuk, Muhammad Zia Karim, Sarah Kim, Stefanie Mӓdler, Ajay Matta, Xiaomei Wang, K. Arne Mehrkens
Low numbers of blood and salivary natural killer cells are associated with a better response to belimumab in primary Sjögren’s syndrome: results of the BELISS study
Raphaèle Seror, Gaétane Nocturne, Thierry Lazure, Houria Hendel-Chavez, Frédéric Desmoulins, Rakiba Belkhir, Philippe Ravaud, Mohcine Benbijja, Vichnou Poirier-Colame, Yacine Taoufik, Xavier Mariette
Variation at interleukin-6 receptor gene is associated to joint damage in rheumatoid arthritis
Maria Lopez-Lasanta, Antonio Julià, Joan Maymó, Benjamín Fernández-Gutierrez, Inmaculada Ureña-Garnica, Francisco J. Blanco, Juan D. Cañete, Mercedes Alperi-López, Alex Olivè, Héctor Corominas, Jesus Tornero, Alba Erra, Miriam Almirall, Nuria Palau, Ana Ortiz, Gabriela Avila, Luis Rodriguez-Rodriguez, Arnald Alonso, Raül Tortosa, Isidoro Gonzalez-Alvaro, Sara Marsal
Efficacy and safety of canakinumab in adolescents and adults with colchicine-resistant familial Mediterranean fever
Ahmet Gül, Huri Ozdogan, Burak Erer, Serdal Ugurlu, Ozgur Kasapcopur, Nicole Davis, Serhan Sevgi
IL2RA is associated with persistence of rheumatoid arthritis
H.W. van Steenbergen, J.A.B. van Nies, A. Ruyssen-Witrand, T.W.J. Huizinga, Al. Cantagrel, F. Berenbaum, A.H.M. van der Helm-van Mil
Certolizumab pegol plus methotrexate 5-year results from the rheumatoid arthritis prevention of structural damage (RAPID) 2 randomized controlled trial and long-term extension in rheumatoid arthritis patients
Josef S. Smolen, Ronald van Vollenhoven, Arthur Kavanaugh, Vibeke Strand, Jiri Vencovsky, Michael Schiff, Robert Landewé, Boulos Haraoui, Catherine Arendt, Irina Mountian, David Carter, Désirée van der Heijde
Does evaluation of the ligamentous compartment enhance diagnostic utility of sacroiliac joint MRI in axial spondyloarthritis?
Ulrich Weber, Walter P. Maksymowych, Stanley M. Chan, Kaspar Rufibach, Susanne J. Pedersen, Zheng Zhao, Veronika Zubler, Mikkel Østergaard, Robert GW Lambert
Macitentan inhibits the transforming growth factor-β profibrotic action, blocking the signaling mediated by the ETR/TβRI complex in systemic sclerosis dermal fibroblasts
Paola Cipriani, Paola Di Benedetto, Piero Ruscitti, Daniela Verzella, Mariafausta Fischietti, Francesca Zazzeroni, Vasiliki Liakouli, Francesco Carubbi, Onorina Berardicurti, Edoardo Alesse, Roberto Giacomelli
O-linked N-acetylglucosamine glycosylation of p65 aggravated the inflammation in both fibroblast-like synoviocytes stimulated by tumor necrosis factor-α and mice with collagen induced arthritis
Han Byeol Kim, Sang Won Lee, Chin Hee Mun, Ji Young Yoon, Jaeyoung Pai, Injae Shin, Yong Beom Park, Soo Kon Lee, Jin Won Cho
Apremilast, a novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectors
Miguel Perez-Aso, M. Carmen Montesinos, Aránzazu Mediero, Tuere Wilder, Peter H. Schafer, Bruce Cronstein
How hepatitis C virus modifies the immunological profile of Sjögren syndrome: analysis of 783 patients
Pilar Brito-Zerón, Hoda Gheitasi, Soledad Retamozo, Albert Bové, María Londoño, Jose-Maria Sánchez-Tapias, Miguel Caballero, Belchin Kostov, Xavier Forns, Srini V. Kaveri, Manuel Ramos-Casals
The inhibitory effects of a RANKL-binding peptide on articular and periarticular bone loss in a murine model of collagen-induced arthritis: a bone histomorphometric study
Genki Kato, Yasuhiro Shimizu, Yuki Arai, Natsuki Suzuki, Yasutaka Sugamori, Miki Maeda, Mariko Takahashi, Yukihiko Tamura, Noriyuki Wakabayashi, Ramachandran Murali, Takashi Ono, Keiichi Ohya, Setsuko Mise-Omata, Kazuhiro Aoki
Serum calprotectin (S100A8/9): an independent predictor of ultrasound synovitis in patients with rheumatoid arthritis
Jana Hurnakova, Jakub Zavada, Petra Hanova, Hana Hulejova, Martin Klein, Herman Mann, Olga Sleglova, Marta Olejarova, Sarka Forejtova, Olga Ruzickova, Martin Komarc, Jiri Vencovsky, Karel Pavelka, Ladislav Senolt
Recombinant human SIRT1 protects against nutrient deprivation-induced mitochondrial apoptosis through autophagy induction in human intervertebral disc nucleus pulposus cells
Shingo Miyazaki, Kenichiro Kakutani, Takashi Yurube, Koichiro Maeno, Toru Takada, Zhongying Zhang, Takuto Kurakawa, Yoshiki Terashima, Masaaki Ito, Takeshi Ueha, Takehiko Matsushita, Ryosuke Kuroda, Masahiro Kurosaka, Kotaro Nishida
Fatigue in chronic inflammation - a link to pain pathways
Karine Louati, Francis Berenbaum
Erratum to: A prospective evaluation of ultrasound as a diagnostic tool in acute microcrystalline arthritis
Pascal Zufferey, Roxana Valcov, Isabelle Fabreguet, Alexandre Dumusc, Patrick Omoumi, Alexander So
Comparative effectiveness and safety of rituximab versus subsequent anti–tumor necrosis factor therapy in patients with rheumatoid arthritis with prior exposure to anti–tumor necrosis factor therapies in the United States Corrona registry
Leslie R. Harrold, George W. Reed, Robert Magner, Ashwini Shewade, Ani John, Jeffrey D. Greenberg, Joel M. Kremer
Enhanced activity of NLRP3 inflammasome in peripheral blood cells of patients with active rheumatoid arthritis
Christianna Choulaki, Garyfallia Papadaki, Argyro Repa, Eleni Kampouraki, Konstantinos Kambas, Konstantinos Ritis, George Bertsias, Dimitrios T. Boumpas, Prodromos Sidiropoulos
Recommendations for resistance training in patients with fibromyalgia
Kim Dupree Jones
Experimental knee pain impairs submaximal force steadiness in isometric, eccentric, and concentric muscle actions
David A. Rice, Peter J. McNair, Gwyn N. Lewis, Jamie Mannion
Association of CXCL10 and CXCL13 levels with disease activity and cutaneous manifestation in active adult-onset Still’s disease
Jae Ho Han, Chang-Hee Suh, Ju-Yang Jung, Jin-Young Nam, Jee Eun Kwon, Hyunee Yim, Hyoun-Ah Kim
Significantly impaired shoulder function in the first years of rheumatoid arthritis: a controlled study
Annelie Bilberg, Tomas Bremell, Istvan Balogh, Kaisa Mannerkorpi
Reanalysis of the Rituximab in ANCA-Associated Vasculitis trial identifies granulocyte subsets as a novel early marker of successful treatment
Mazen Nasrallah, Yannick Pouliot, Bjoern Hartmann, Patrick Dunn, Elizabeth Thomson, Jeffrey Wiser, Atul J. Butte
Body mass index modulates the relationship of sugar-sweetened beverage intake with serum urate concentrations and gout
Nicola Dalbeth, Amanda Phipps-Green, Meaghan E. House, Gregory D. Gamble, Anne Horne, Lisa K. Stamp, Tony R. Merriman
Overexpression of MMP13 in human osteoarthritic cartilage is associated with the SMAD-independent TGF-β signalling pathway
Erfan Aref-Eshghi, Ming Liu, Patricia E. Harper, Jules Doré, Glynn Martin, Andrew Furey, Roger Green, Proton Rahman, Guangju Zhai
Sponyloarthritis features forecasting the presence of HLA-B27 or sacroiliitis on magnetic resonance imaging in patients with suspected axial spondyloarthritis: results from a cross-sectional study in the ESPeranza Cohort
Victoria Navarro-Compán, Eugenio de Miguel, Désirée van der Heijde, Robert Landewé, Raquel Almodóvar, Carlos Montilla, Emma Beltrán, Pedro Zarco
Subclinical synovitis detected by macrophage PET, but not MRI, is related to short-term flare of clinical disease activity in early RA patients: an exploratory study
Yoony Y. J. Gent, Marieke M. ter Wee, Alexandre E. Voskuyl, Debby den Uyl, Nazanin Ahmadi, Cristina Dowling, Cornelis van Kuijk, Otto S. Hoekstra, Maarten Boers, Willem F. Lems, Conny J. van der Laken
Effect of dexamethasone prodrug on inflamed temporomandibular joints in juvenile rats
Mitchell Knudsen, Matthew Bury, Callie Holwegner, Adam L. Reinhardt, Fang Yuan, Yijia Zhang, Peter Giannini, David B. Marx, Dong Wang, Richard A. Reinhardt
Response to peripheral immune stimulation within the brain: magnetic resonance imaging perspective of treatment success
Marina Sergeeva, Jürgen Rech, Georg Schett, Andreas Hess
Histone deacetylase inhibition activates Nrf2 and protects against osteoarthritis
Dawei Cai, Shasha Yin, Jun Yang, Qing Jiang, Wangsen Cao
Bone marrow lesions can be subtyped into groups with different clinical outcomes using two magnetic resonance imaging (MRI) sequences
Anita E. Wluka, Andrew J. Teichtahl, Rheza Maulana, Bonnie M. Liu, Yuanyuan Wang, Graham G. Giles, Richard O’Sullivan, David Findlay, Flavia M. Cicuttini
Preserved skeletal muscle protein anabolic response to acute exercise and protein intake in well-treated rheumatoid arthritis patients
Ulla Ramer Mikkelsen, Kasper Dideriksen, Mads Bisgaard Andersen, Anders Boesen, Nikolai Mølkjær Malmgaard-Clausen, Inge Juul Sørensen, Peter Schjerling, Michael Kjær, Lars Holm
Effects of non-pharmacological interventions on inflammatory biomarker expression in patients with fibromyalgia: a systematic review
Kenji Sanada, Marta Alda Díez, Montserrat Salas Valero, María Cruz Pérez-Yus, Marcelo M P Demarzo, Mauro García-Toro, Javier García-Campayo
Diagnostic performance of measuring antibodies to the glycopeptidolipid core antigen specific to Mycobacterium avium complex in patients with rheumatoid arthritis: results from a cross-sectional observational study
Wataru Hirose, Takashi Uchiyama, Asuka Nemoto, Masayoshi Harigai, Kenji Itoh, Toshiaki Ishizuka, Mitsuyo Matsumoto, Kazue Yamaoka, Toshihiro Nanki
Systematic review and meta-analysis of the sero-epidemiological association between Epstein-Barr virus and rheumatoid arthritis
Robert J. Ball, Alison Avenell, Lorna Aucott, Peter Hanlon, Mark A. Vickers
CD1a+ survivin+ dendritic cell infiltration in dermal lesions of systemic sclerosis
Sho Mokuda, Tatsuhiko Miyazaki, Yoshifumi Ubara, Masamoto Kanno, Eiji Sugiyama, Kiyoshi Takasugi, Junya Masumoto
An investigation of the added value of an ACPA multiplex assay in an early rheumatoid arthritis setting
Jurgen van Heemst, Leendert A. Trouw, Leonor Nogueira, Hanna W. van Steenbergen, Annette H. M. van der Helm-van Mil, Cornelia F. Allaart, Guy Serre, Rikard Holmdahl, Tom W. J. Huizinga, René E. M. Toes, Diane van der Woude
Early treatment with hydroxychloroquine prevents the development of endothelial dysfunction in a murine model of systemic lupus erythematosus
Agostino Virdis, Chiara Tani, Emiliano Duranti, Sabrina Vagnani, Linda Carli, Anja A. Kühl, Anna Solini, Chiara Baldini, Rosaria Talarico, Stefano Bombardieri, Stefano Taddei, Marta Mosca
Low-intensity pulsed ultrasound rescues insufficient salivary secretion in autoimmune sialadenitis
Minami Sato, Shingo Kuroda, Karima Qurnia Mansjur, Ganzorig Khaliunaa, Kumiko Nagata, Shinya Horiuchi, Toshihiro Inubushi, Yoshiko Yamamura, Masayuki Azuma, Eiji Tanaka
Rosuvastatin improves endothelial function in patients with inflammatory joint diseases, longitudinal associations with atherosclerosis and arteriosclerosis: results from the RORA-AS statin intervention study
Eirik Ikdahl, Jonny Hisdal, Silvia Rollefstad, Inge C. Olsen, Tore K. Kvien, Terje R. Pedersen, Anne Grete Semb
Serum 14-3-3η level is associated with severity and clinical outcomes of rheumatoid arthritis, and its pretreatment level is predictive of DAS28 remission with tocilizumab
Shintaro Hirata, Anthony Marotta, Yuan Gui, Kentaro Hanami, Yoshiya Tanaka
Non-adherence to disease-modifying antirheumatic drugs is associated with higher disease activity in early arthritis patients in the first year of the disease
Annelieke Pasma, Charlotte V. Schenk, Reinier Timman, Jan J. V. Busschbach, Bart J.F. van den Bemt, Esmeralda Molenaar, Willemijn H. van der Laan, Saskia Schrauwen, Adriaan van’t Spijker, Johanna M. W. Hazes
Safety, tolerability, pharmacokinetics, and efficacy of AMG 403, a human anti-nerve growth factor monoclonal antibody, in two phase I studies with healthy volunteers and knee osteoarthritis subjects
Jason M. Gow, Wayne H. Tsuji, Gary J. Williams, Daniel Mytych, David Sciberras, Shawn L. Searle, Tim Mant, John P. Gibbs
Serum hyaluronic acid concentration predicts the progression of joint space narrowing in normal knees and established knee osteoarthritis – a five-year prospective cohort study
Eiji Sasaki, Eiichi Tsuda, Yuji Yamamoto, Shugo Maeda, Ryo Inoue, Daisuke Chiba, Hiroshi Fujita, Ippei Takahashi, Takashi Umeda, Shigeyuki Nakaji, Yasuyuki Ishibashi
High serum cholesterol predicts rheumatoid arthritis in women, but not in men: a prospective study
Carl Turesson, Ulf Bergström, Mitra Pikwer, Jan-Åke Nilsson, Lennart TH Jacobsson
Bach1 deficiency reduces severity of osteoarthritis through upregulation of heme oxygenase-1
Tsuyoshi Takada, Shigeru Miyaki, Hiroyuki Ishitobi, Yuya Hirai, Tomoyuki Nakasa, Kazuhiko Igarashi, Martin K. Lotz, Mitsuo Ochi
Role of PTPN22 and CSK gene polymorphisms as predictors of susceptibility and clinical heterogeneity in patients with Henoch-Schönlein purpura (IgA vasculitis)
Raquel López-Mejías, Fernanda Genre, Sara Remuzgo-Martínez, Belén Sevilla Pérez, Santos Castañeda, Javier Llorca, Norberto Ortego-Centeno, Begoña Ubilla, Verónica Mijares, Trinitario Pina, Vanesa Calvo-Río, Natalia Palmou, José A. Miranda-Filloy, Antonio Navas Parejo, Diego Argila, Javier Sánchez-Pérez, Esteban Rubio, Manuel León Luque, Juan María Blanco-Madrigal, Eva Galíndez-Aguirregoikoa, J. Gonzalo Ocejo-Vinyals, Javier Martín, Ricardo Blanco, Miguel A. González-Gay
Spatiotemporal gait compensations following medial collateral ligament and medial meniscus injury in the rat: correlating gait patterns to joint damage
Heidi E. Kloefkorn, Brittany Y. Jacobs, Ayomiposi M. Loye, Kyle D. Allen
Multiplicative interaction of functional inflammasome genetic variants in determining the risk of gout
Cushla McKinney, Lisa K. Stamp, Nicola Dalbeth, Ruth K. Topless, Richard O. Day, Diluk RW Kannangara, Kenneth M. Williams, Matthijs Janssen, Timothy L. Jansen, Leo A. Joosten, Timothy R. Radstake, Philip L. Riches, Anne-Kathrin Tausche, Frederic Lioté, Alexander So, Tony R. Merriman
Continuously elevated serum matrix metalloproteinase-3 for 3 ~ 6 months predict one-year radiographic progression in rheumatoid arthritis: a prospective cohort study
Jian-Da Ma, Xiu-Ning Wei, Dong-Hui Zheng, Ying-Qian Mo, Le-Feng Chen, Xiang Zhang, Jin-Hua Li, Lie Dai
Celebrating the past, concentrating on the future: the next decade for AR&T
Christopher D. Buckley, Harris Perlman
Conditional deletion of caspase-8 in macrophages alters macrophage activation in a RIPK-dependent manner
Carla M. Cuda, Alexander V. Misharin, Sonal Khare, Rana Saber, FuNien Tsai, Amy M. Archer, Philip J. Homan, G. Kenneth Haines III, Jack Hutcheson, Andrea Dorfleutner, G. R. Scott Budinger, Christian Stehlik, Harris Perlman
Impaired function of endothelial progenitor cells in children with primary systemic vasculitis
Ying Hong, Despina Eleftheriou, Nigel J. Klein, Paul A. Brogan
Analyzing pathogenic (double-stranded (ds) DNA-specific) plasma cells via immunofluorescence microscopy
Oliver Winter, Stephanie Musiol, Melissa Schablowsky, Qingyu Cheng, Laleh Khodadadi, Falk Hiepe
The prevalence of vertebral fractures in spondyloarthritis: relation to disease characteristics, bone mineral density, syndesmophytes and history of back pain and trauma
Piet Geusens, Liesbeth De Winter, Dana Quaden, Johan Vanhoof, Debby Vosse, Joop van den Bergh, Veerle Somers
Methotrexate polyglutamates as a potential marker of adherence to long-term therapy in children with juvenile idiopathic arthritis and juvenile dermatomyositis: an observational, cross-sectional study
Ahmed F. Hawwa, AbdelQader AlBawab, Madeleine Rooney, Lucy R. Wedderburn, Michael W. Beresford, James C. McElnay
Utility of untimed single urine protein/creatinine ratio as a substitute for 24-h proteinuria for assessment of proteinuria in systemic lupus erythematosus
Jorge Medina-Rosas, Dafna D. Gladman, Jiandong Su, Arthy Sabapathy, Murray B. Urowitz, Zahi Touma
A Dose–response relationship between severity of disc degeneration and intervertebral disc height in the lumbosacral spine
Andrew J. Teichtahl, Donna M. Urquhart, Yuanyuan Wang, Anita E. Wluka, Stephane Heritier, Flavia M. Cicuttini
Association of physical activity and physical performance with tibial cartilage volume and bone area in young adults
Benny Antony, Alison Venn, Flavia Cicuttini, Lyn March, Leigh Blizzard, Terence Dwyer, Marita Cross, Graeme Jones, Changhai Ding
Antigen-induced arthritis in rats is associated with increased growth-associated protein 43–positive intraepidermal nerve fibres remote from the joint
Elisabeth Jochmann, Michael Karl Boettger, Praveen Anand, Hans-Georg Schaible
Direct effects of HP Acthar Gel® on human B lymphocyte activation in vitro
Nancy J. Olsen, Dima A. Decker, Paul Higgins, Patrice M. Becker, Carl A. McAloose, Ann L. Benko, William J. Kovacs
Update on mesenchymal stem cell-based therapy in lupus and scleroderma
Audrey Cras, Dominique Farge, Thierry Carmoi, Jean-Jacques Lataillade, Dan Dan Wang, Lingyun Sun
HIF-2α-induced chemokines stimulate motility of fibroblast-like synoviocytes and chondrocytes into the cartilage-pannus interface in experimental rheumatoid arthritis mouse models
Yun Hyun Huh, Gyuseok Lee, Keun-Bae Lee, Jeong-Tae Koh, Jang-Soo Chun, Je-Hwang Ryu
A new look at arthritis management: nociceptive reflex excitability as a pain biomarker
Carol A. Courtney
Is urate crystal precipitation a predictor of cardiovascular risk in hyperuricemic patients? A Danish cohort study
Kasper Søltoft Larsen, Anton Pottegård, Hanne Lindegaard, Jesper Hallas
Different responses to treatment across classified diseases and severities in Japanese patients with microscopic polyangiitis and granulomatosis with polyangiitis: a nationwide prospective inception cohort study
Ken-ei Sada, Masahiro Yamamura, Masayoshi Harigai, Takao Fujii, Yoshinari Takasaki, Koichi Amano, Shouichi Fujimoto, Eri Muso, Yohko Murakawa, Yoshihiro Arimura, Hirofumi Makino
PTGER4 gene variant rs76523431 is a candidate risk factor for radiological joint damage in rheumatoid arthritis patients: a genetic study of six cohorts
Luis Rodriguez-Rodriguez, Jose Ivorra-Cortes, F. David Carmona, Javier Martín, Alejandro Balsa, Hanna W. van Steenbergen, Annette H. M. van der Helm-van Mil, Isidoro González-Álvaro, Benjamín Fernandez-Gutiérrez
Effects of tofacitinib monotherapy on patient-reported outcomes in a randomized phase 3 study of patients with active rheumatoid arthritis and inadequate responses to DMARDs
Vibeke Strand, Joel Kremer, Gene Wallenstein, Keith S. Kanik, Carol Connell, David Gruben, Samuel H. Zwillich, Roy Fleischmann
68Ga-DOTA-Siglec-9 – a new imaging tool to detect synovitis
Helena Virtanen, Anu Autio, Riikka Siitonen, Heidi Liljenbäck, Tiina Saanijoki, Petteri Lankinen, Jussi Mäkilä, Meeri Käkelä, Jarmo Teuho, Nina Savisto, Kimmo Jaakkola, Sirpa Jalkanen, Anne Roivainen
A novel method to detect articular chondrocyte death during early stages of osteoarthritis using a non-invasive ApoPep-1 probe
Xiangguo Che, Lianhua Chi, Clara Yongjoo Park, Gyoung-Ho Cho, Narae Park, Seong-Gon Kim, Byung-Heon Lee, Je-Yong Choi
Investigation of the cytokine response to NF-κB decoy oligonucleotide coated polysaccharide based nanoparticles in rheumatoid arthritis in vitro models
Patricia R. Wardwell, Martin B. Forstner, Rebecca A. Bader
Erratum to: Continuously elevated serum matrix metalloproteinase-3 for 3 ~ 6 months predict one-year radiographic progression in rheumatoid arthritis: a prospective cohort study
Jian-Da Ma, Xiu-Ning Wei, Dong-Hui Zheng, Ying-Qian Mo, Le-Feng Chen, Xiang Zhang, Jin-Hua Li, Lie Dai
Measuring the positive psychological well-being of people with rheumatoid arthritis: a cross-sectional validation of the subjective vitality scale
Peter C. Rouse, Jet J. J. C. S. Veldhuijzen Van Zanten, Nikos Ntoumanis, George S. Metsios, Chen-an Yu, George D. Kitas, Joan L. Duda
Semaphorin 4A as novel regulator and promising therapeutic target in rheumatoid arthritis
Svetlana P. Chapoval
p21 deficiency is susceptible to osteoarthritis through STAT3 phosphorylation
Shinya Hayashi, Takaaki Fujishiro, Shingo Hashimoto, Noriyuki Kanzaki, Nobuaki Chinzei, Shinsuke Kihara, Koji Takayama, Tomoyuki Matsumoto, Kotaro Nishida, Masahiro Kurosaka, Ryosuke Kuroda
Effect of antiresorptive and anabolic bone therapy on development of osteoarthritis in a posttraumatic rat model of OA
Cedo M. Bagi, Edwin Berryman, David E. Zakur, Dean Wilkie, Catharine J. Andresen
Excessive reactive oxygen species are therapeutic targets for intervertebral disc degeneration
Satoshi Suzuki, Nobuyuki Fujita, Naobumi Hosogane, Kota Watanabe, Ken Ishii, Yoshiaki Toyama, Keiyo Takubo, Keisuke Horiuchi, Takeshi Miyamoto, Masaya Nakamura, Morio Matsumoto
Higher education is associated with a better rheumatoid arthritis outcome concerning for pain and function but not disease activity: results from the EIRA cohort and Swedish rheumatology register
Xia Jiang, Maria E. C. Sandberg, Saedis Saevarsdottir, Lars Klareskog, Lars Alfredsson, Camilla Bengtsson
A large infrapatellar fat pad protects against knee pain and lateral tibial cartilage volume loss
Andrew J. Teichtahl, Ema Wulidasari, Sharmayne R. E. Brady, Yuanyuan Wang, Anita E. Wluka, Changhai Ding, Graham G. Giles, Flavia M. Cicuttini
Incidence and complications of interstitial lung disease in users of tocilizumab, rituximab, abatacept and anti-tumor necrosis factor α agents, a retrospective cohort study
Jeffrey R. Curtis, Khaled Sarsour, Pavel Napalkov, Laurie A. Costa, Kathy L. Schulman
Fibronectin fragment-induced expression of matrix metalloproteinases is mediated by MyD88-dependent TLR-2 signaling pathway in human chondrocytes
Hyun Sook Hwang, Su Jin Park, Eun Jeong Cheon, Mi Hyun Lee, Hyun Ah Kim
Anti-inflammatory effects of N-acylethanolamines in rheumatoid arthritis synovial cells are mediated by TRPV1 and TRPA1 in a COX-2 dependent manner
Torsten Lowin, Martin Apitz, Sven Anders, Rainer H. Straub
Development of key performance indicators to evaluate centralized intake for patients with osteoarthritis and rheumatoid arthritis
Claire E. Barber, Jatin N. Patel, Linda Woodhouse, Christopher Smith, Stephen Weiss, Joanne Homik, Sharon LeClercq, Dianne Mosher, Tanya Christiansen, Jane Squire Howden, Tracy Wasylak, James Greenwood-Lee, Andrea Emrick, Esther Suter, Barb Kathol, Dmitry Khodyakov, Sean Grant, Denise Campbell-Scherer, Leah Phillips, Jennifer Hendricks, Deborah A. Marshall
Gout, not hyperuricemia alone, impairs left ventricular diastolic function
Jing-Chi Lin, Chun-Liang Lin, Mien-Cheng Chen, Pey-Jium Chang, Shih-Tai Chang, Chang-Min Chung, Kuo-Li Pan
A subset of CD163+ macrophages displays mixed polarizations in discoid lupus skin
Benjamin F. Chong, Lin-chiang Tseng, Gregory A. Hosler, Noelle M. Teske, Song Zhang, David R. Karp, Nancy J. Olsen, Chandra Mohan
Twenty-eight-week results from the REALISTIC phase IIIb randomized trial: efficacy, safety and predictability of response to certolizumab pegol in a diverse rheumatoid arthritis population
Michael E. Weinblatt, Roy Fleischmann, Ronald F. van Vollenhoven, Paul Emery, Tom WJ Huizinga, Maurizio Cutolo, Désirée van der Heijde, Benjamin Duncan, Owen Davies, Kristel Luijtens, Maxime Dougados
Cross-talk between bone morphogenetic proteins and inflammatory pathways
Peter M. van der Kraan, Esmeralda N. Blaney Davidson
Cartilage stem/progenitor cells are activated in osteoarthritis via interleukin-1β/nerve growth factor signaling
Yangzi Jiang, Changchang Hu, Shuting Yu, Junwei Yan, Hsuan Peng, Hong Wei Ouyang, Rocky S. Tuan
Is RANKL inhibition both anti-resorptive and anabolic in rheumatoid arthritis?
Natalie A. Sims, Evange Romas
High frequency ultrasound of skin involvement in systemic sclerosis – a follow-up study
Roger Hesselstrand, Johanna Carlestam, Marie Wildt, Gunnel Sandqvist, Kristofer Andréasson
Tumor necrosis factor-α blockade in recurrent and disabling chronic sciatica associated with post-operative peridural lumbar fibrosis: results of a double-blind, placebo randomized controlled study
Christelle Nguyen, Clémence Palazzo, Sophie Grabar, Antoine Feydy, Katherine Sanchez, Nathalie Zee, Laurent Quinquis, Myriam Ben Boutieb, Michel Revel, Marie-Martine Lefèvre-Colau, Serge Poiraudeau, François Rannou
Citral alleviates an accelerated and severe lupus nephritis model by inhibiting the activation signal of NLRP3 inflammasome and enhancing Nrf2 activation
Shuk-Man Ka, Jung-Chen Lin, Tsai-Jung Lin, Feng-Cheng Liu, Louis Kuoping Chao, Chen-Lung Ho, Li-Tzu Yeh, Huey-Kang Sytwu, Kuo-Feng Hua, Ann Chen
Inhibition of angiogenesis by platelets in systemic sclerosis patients
Daniela Hirigoyen, Paula I. Burgos, Veronica Mezzano, Josefina Duran, Magaly Barrientos, Claudia G. Saez, Olga Panes, Diego Mezzano, Mirentxu Iruretagoyena
Association between environmental exposures and granulomatosis with polyangiitis in Canterbury, New Zealand
Lisa K. Stamp, Peter T. Chapman, Janine Francis, Lutz Beckert, Christopher Frampton, Richard A. Watts, John L. O’Donnell
Interleukin-6-dependent influence of nociceptive sensory neurons on antigen-induced arthritis
Matthias Ebbinghaus, Gisela Segond von Banchet, Julia Massier, Mieczyslaw Gajda, Rolf Bräuer, Michaela Kress, Hans-Georg Schaible
Serum leptin and serum leptin/serum leptin receptor ratio imbalance in obese rheumatoid arthritis patients positive for anti-cyclic citrullinated peptide antibodies
Eduardo Gómez-Bañuelos, Rosa Elena Navarro-Hernández, Fernanda Corona-Meraz, Perla Monserrat Madrigal-Ruíz, Beatríz Teresita Martín-Marquez, Oscar Enrique Pizano-Martinez, Jorge Aguilar-Arreola, Paul Jacob Perez-Cruz, Hector Macias-Reyes, Laura Gonzalez-Lopez, Jorge Ivan Gamez-Nava, Mario Salazar-Páramo, Monica Vazquez-del Mercado
Probability and heritability estimates on primary osteoarthritis of the hip leading to total hip arthroplasty: a nationwide population based follow-up study in Danish twins
Søren Glud Skousgaard, Jacob Hjelmborg, Axel Skytthe, Lars Peter Andreas Brandt, Sören Möller, Søren Overgaard
Peripheral blood natural killer cell percentages in granulomatosis with polyangiitis correlate with disease inactivity and stage
Wolfgang Merkt, Prisca Sturm, Felix Lasitschka, Theresa Tretter, Carsten Watzl, Daniel Saure, Michael Hundemer, Vedat Schwenger, Norbert Blank, Hanns-Martin Lorenz, Adelheid Cerwenka
Antibodies against High Mobility Group Box protein-1 (HMGB1) versus other anti-nuclear antibody fine-specificities and disease activity in systemic lupus erythematosus
Lina Wirestam, Hanna Schierbeck, Thomas Skogh, Iva Gunnarsson, Lars Ottosson, Helena Erlandsson-Harris, Jonas Wetterö, Christopher Sjöwall
The specificity of anti-carbamylated protein antibodies for rheumatoid arthritis in a setting of early arthritis
Jing Shi, Hanna W. van Steenbergen, Jessica A. B. van Nies, E. W. Nivine Levarht, Tom W. J. Huizinga, Annette H. M. van der Helm-van Mil, René E. M. Toes, Leendert A. Trouw
Soluble PD-1 aggravates progression of collagen-induced arthritis through Th1 and Th17 pathways
Cuiping Liu, Juean Jiang, Li Gao, Xiaoting Wang, Xiaohan Hu, Min Wu, Jian Wu, Ting Xu, Qin Shi, Xueguang Zhang
Serum tenascin-C discriminates patients with active SLE from inactive patients and healthy controls and predicts the need to escalate immunosuppressive therapy: a cohort study
Jakub Závada, Michal Uher, Radka Svobodová, Marta Olejárová, Markéta Hušáková, Hana Ciferská, Hana Hulejová, Michal Tomčík, Ladislav Šenolt, Jiří Vencovský
An HLA-C amino-acid variant in addition to HLA-B*27 confers risk for ankylosing spondylitis in the Korean population
Kwangwoo Kim, So-Young Bang, Seunghun Lee, Hye-Soon Lee, Seung-Cheol Shim, Young Mo Kang, Chang-Hee Suh, Celi Sun, Swapan K. Nath, Sang-Cheol Bae, Tae-Hwan Kim
Impact of certolizumab pegol on patient-reported outcomes in rheumatoid arthritis and correlation with clinical measures of disease activity
Janet Pope, Clifton O. Bingham III, Roy M. Fleischmann, Maxime Dougados, Elena M. Massarotti, Jürgen Wollenhaupt, Benjamin Duncan, Geoffroy Coteur, Michael E. Weinblatt
CCR6+ Th cell populations distinguish ACPA positive from ACPA negative rheumatoid arthritis
Sandra M. J. Paulissen, Jan Piet van Hamburg, Nadine Davelaar, Heleen Vroman, Johanna M. W. Hazes, Pascal H. P. de Jong, Erik Lubberts
Statistical considerations for stopping systemic lupus erythematosus clinical trials earlier
Robert A. Lew, Matthew H. Liang, Gheorghe Doros
Aesthetic discomfort in hand osteoarthritis: results from the LIège Hand Osteoarthritis Cohort (LIHOC)
Audrey Neuprez, Olivier Bruyère, Emmanuel Maheu, Nadia Dardenne, Nansa Burlet, Pieter D’Hooghe, Stéphan Distèche, Jean-Yves Reginster
BAFF inhibition does not significantly impair immunization responses in patients with rheumatoid arthritis
Clifton O. Bingham III, Kevin L. Winthrop, Lili Yang, Chin Lee, Wendy J. Komocsar
Determinants of patient preferences for total knee replacement: African-Americans and whites
C. Kent Kwoh, Ernest R. Vina, Yona K. Cloonan, Michael J. Hannon, Robert M. Boudreau, Said A. Ibrahim
Discovery of a novel genetic susceptibility locus on X chromosome for systemic lupus erythematosus
Zhengwei Zhu, Zhuoyuan Liang, Herty Liany, Chao Yang, Leilei Wen, Zhiming Lin, Yujun Sheng, Yan Lin, Lei Ye, Yuyan Cheng, Yan Chang, Lu Liu, Lulu Yang, Yinjuan Shi, Changbing Shen, Fusheng Zhou, Xiaodong Zheng, Jun Zhu, Bo Liang, Yantao Ding, Yi Zhou, Xianyong Yin, Huayang Tang, Xianbo Zuo, Liangdan Sun, Jin-Xin Bei, Jianjun Liu, Sen Yang, Wanling Yang, Yong Cui, Xuejun Zhang
High level of interleukin-32 gamma in the joint of ankylosing spondylitis is associated with osteoblast differentiation
Eun-Ju Lee, Eun-Jin Lee, Yeon-Ho Chung, Da-Hyun Song, Seokchan Hong, Chang-Keun Lee, Bin Yoo, Tae-Hwan Kim, Ye-Soo Park, Soo-Hyun Kim, Eun-Ju Chang, Yong-Gil Kim
Stratifying primary Sjögren’s syndrome: killers in the balance?
Simon J. Bowman, Benjamin A. Fisher
Triamcinolone acetonide activates an anti-inflammatory and folate receptor–positive macrophage that prevents osteophytosis in vivo
Michiel Siebelt, Nicoline Korthagen, Wu Wei, Harald Groen, Yvonne Bastiaansen-Jenniskens, Christina Müller, Jan Hendrik Waarsing, Marion de Jong, Harrie Weinans
The interaction of lubricin/proteoglycan 4 (PRG4) with toll-like receptors 2 and 4: an anti-inflammatory role of PRG4 in synovial fluid
Ali Alquraini, Steven Garguilo, Gerard D’Souza, Ling X. Zhang, Tannin A. Schmidt, Gregory D. Jay, Khaled A. Elsaid
Retraction Note: Mast cells are the main interleukin 17-positive cells in anticitrullinated protein antibody-positive and -negative rheumatoid arthritis and osteoarthritis synovium
Jolien Suurmond, Annemarie L. Dorjée, Mariëtte R. Boon, Edward F. Knol, Tom W. J. Huizinga, René E. M. Toes, Annemie J. M. Schuerwegh
A low cortisol response to stress is associated with musculoskeletal pain combined with increased pain sensitivity in young adults: a longitudinal cohort study
Markus Paananen, Peter O’Sullivan, Leon Straker, Darren Beales, Pieter Coenen, Jaro Karppinen, Craig Pennell, Anne Smith
Simultaneous inhibition of JAK and SYK kinases ameliorates chronic and destructive arthritis in mice
Alba Llop-Guevara, Mónica Porras, Carla Cendón, Irene Di Ceglie, Francesco Siracusa, Federica Madarena, Vagelis Rinotas, Lluís Gómez, Peter L. van Lent, Eleni Douni, Hyun Dong Chang, Thomas Kamradt, Juan Román
Effect of abatacept on the immunogenicity of 23-valent pneumococcal polysaccharide vaccination (PPSV23) in rheumatoid arthritis patients
Kiyoshi Migita, Yukihiro Akeda, Manabu Akazawa, Shigeto Tohma, Fuminori Hirano, Haruko Ideguchi, Hideko Kozuru, Yuka Jiuchi, Ryutaro Matsumura, Eiichi Suematsu, Tomoya Miyamura, Shunsuke Mori, Takahiro Fukui, Yasumori Izumi, Nozomi Iwanaga, Hiroshi Tsutani, Kouichirou Saisyo, Takao Yamanaka, Shiro Ohshima, Naoya Mori, Akinori Matsumori, Koichiro Takahi, Shigeru Yoshizawa, Yojiro Kawabe, Yasuo Suenaga, Tetsuo Ozawa, Norikazu Hamada, Yasuhiro Komiya, Toshihiro Matsui, Hiroshi Furukawa, Kazunori Oishi
Parity influences the severity of ACPA-negative early rheumatoid arthritis: a cohort study based on the Swedish EIRA material
Mitra Pikwer, Cecilia Orellana, Henrik Källberg, Andreas Pikwer, Carl Turesson, Lars Klareskog, Lars Alfredsson, Saedis Saevarsdottir, Camilla Bengtsson
Investigating CD11c expression as a potential genomic biomarker of response to TNF inhibitor biologics in whole blood rheumatoid arthritis samples
Samantha Louise Smith, Stephen Eyre, Annie Yarwood, Kimme Hyrich, Ann W. Morgan, A. G. Wilson, John Isaacs, Darren Plant, Anne Barton
The effectiveness of low-level laser therapy for nonspecific chronic low back pain: a systematic review and meta-analysis
ZeYu Huang, Jun Ma, Jing Chen, Bin Shen, FuXing Pei, Virginia Byers Kraus
Cytokine preconditioning of engineered cartilage provides protection against interleukin-1 insult
Andrea R. Tan, Curtis D. VandenBerg, Mukundan Attur, Steven B. Abramson, Martin M Knight, J. Chloe Bulinski, Gerard A. Ateshian, James L Cook, Clark T. Hung
Systematic review and meta-analysis of serious infections with tofacitinib and biologic disease-modifying antirheumatic drug treatment in rheumatoid arthritis clinical trials
Vibeke Strand, Sima Ahadieh, Jonathan French, Jamie Geier, Sriram Krishnaswami, Sujatha Menon, Tina Checchio, Thomas G. Tensfeldt, Elaine Hoffman, Richard Riese, Mary Boy, Juan J. Gómez-Reino
The HLA-B*35 allele modulates ER stress, inflammation and proliferation in PBMCs from Limited Cutaneous Systemic Sclerosis patients
Stefania Lenna, Shervin Assassi, G. Alessandra Farina, Julio C. Mantero, Raffaella Scorza, Robert Lafyatis, Harrison W. Farber, Maria Trojanowska
Supplement of 5-hydroxytryptophan before induction suppresses inflammation and collagen-induced arthritis
Tao-Hsiang Yang, Peng-Yang Hsu, Menghsiao Meng, Che-Chun Su
Serological epitope profile of anti-Ro52–positive patients with systemic autoimmune rheumatic diseases
Maria Infantino, Francesca Meacci, Valentina Grossi, Maurizio Benucci, Gabriella Morozzi, Elio Tonutti, Marilina Tampoia, Antonina Ott, Wolfgang Meyer, Fabiola Atzeni, Piercarlo Sarzi-Puttini, Mariangela Manfredi, Nicola Bizzaro
Racial differences in associations between baseline patterns of radiographic osteoarthritis and multiple definitions of progression of hip osteoarthritis: the Johnston County Osteoarthritis Project
Bridget Foley, Rebecca J. Cleveland, Jordan B. Renner, Joanne M. Jordan, Amanda E. Nelson
Minorities with lupus nephritis and medications: a study of facilitators to medication decision-making
Jasvinder A. Singh, Haiyan Qu, Jinoos Yazdany, Winn Chatham, Richard Shewchuk
IgG4-related sialadenitis: IgG4 is helpful, but biopsies are still crucial
Torsten Witte, Hendrik Schulze-Koops
Inflammatory but not apoptotic death of granulocytes citrullinates fibrinogen
Nathalie E. Blachère, Salina Parveen, John Fak, Mayu O. Frank, Dana E. Orange
Nerves are more abundant than blood vessels in the degenerate human intervertebral disc
Abbie L. A. Binch, Ashley A. Cole, Lee M. Breakwell, Antony L. R. Michael, Neil Chiverton, Laura B. Creemers, Alison K. Cross, Christine L. Le Maitre
Prognostic value of anti-CRP antibodies in lupus nephritis in long-term follow-up
Satu Sinikka Pesickova, Romana Rysava, Martin Lenicek, Libor Vitek, Eliska Potlukova, Zdenka Hruskova, Eva Jancova, Eva Honsova, Jakub Zavada, Marten Trendelenburg, Vladimir Tesar
Predictors of lung function decline in scleroderma-related interstitial lung disease based on high-resolution computed tomography: implications for cohort enrichment in systemic sclerosis–associated interstitial lung disease trials
Dinesh Khanna, Vivek Nagaraja, Chi-hong Tseng, Fereidoun Abtin, Robert Suh, Grace Kim, Athol Wells, Daniel E. Furst, Philip J. Clements, Michael D. Roth, Donald P. Tashkin, Jonathan Goldin
Hedgehog signalling does not stimulate cartilage catabolism and is inhibited by Interleukin-1β
Clare L. Thompson, Riana Patel, Terri-Ann N. Kelly, Angus K. T. Wann, Clark T. Hung, J. Paul Chapple, Martin M. Knight
Autophagy induction contributes to the resistance to methotrexate treatment in rheumatoid arthritis fibroblast-like synovial cells through high mobility group box chromosomal protein 1
Ke Xu, Yong-song Cai, She-Min Lu, Xiao-li Li, Lin Liu, Zhong Li, Hui Liu, Peng Xu
Half of UK patients with rheumatoid arthritis are prescribed oral glucocorticoid therapy in primary care: a retrospective drug utilisation study
Rachel J. Black, Rebecca M. Joseph, Benjamin Brown, Mohammad Movahedi, Mark Lunt, William G. Dixon
In vivo optical imaging of early osteoarthritis using an antibody specific to damaged arthritic cartilage
Ngee Han Lim, Tonia L. Vincent, Ahuva Nissim
Alterations of bone mineral density, bone microarchitecture and strength in patients with ankylosing spondylitis: a cross-sectional study using high-resolution peripheral quantitative computerized tomography and finite element analysis
Nisha Nigil Haroon, Eva Szabo, Janet M. Raboud, Heather Mcdonald-Blumer, Lydia Fung, Robert G. Josse, Robert D. Inman, Angela M. Cheung
Comparison of non-radiographic axial spondyloarthritis and ankylosing spondylitis patients – baseline characteristics, treatment adherence, and development of clinical variables during three years of anti-TNF therapy in clinical practice
Johan K. Wallman, Meliha C. Kapetanovic, Ingemar F. Petersson, Pierre Geborek, Lars Erik Kristensen
Soluble biglycan: a potential mediator of cartilage degradation in osteoarthritis
Goncalo Barreto, Antti Soininen, Pekka Ylinen, Jerker Sandelin, Yrjö T. Konttinen, Dan C. Nordström, Kari K. Eklund
The beneficial effects of Tai Chi exercise on endothelial function and arterial stiffness in elderly women with rheumatoid arthritis
Jeong-Hun Shin, Yonggu Lee, Soon Gil Kim, Bo Youl Choi, Hye-Soon Lee, So-Young Bang
HDACi and Nrf2: not from alpha to omega but from acetylation to OA
Holger Jahr
Dysregulation of RasGRP1 in rheumatoid arthritis and modulation of RasGRP3 as a biomarker of TNFα inhibitors
Marie-Laure Golinski, Thibault Vandhuick, Céline Derambure, Manuel Fréret, Matthieu Lecuyer, Clément Guillou, Martine Hiron, Olivier Boyer, Xavier Le Loët, Olivier Vittecoq, Thierry Lequerré
Usefulness of using laser-induced photoacoustic measurement and 3.0 Tesla MRI to assess knee cartilage damage: a comparison study
Taku Ukai, Masato Sato, Miya Ishihara, Munetaka Yokoyama, Tomonori Takagaki, Genya Mitani, Yoshiki Tani, Tomohiro Yamashita, Yutaka Imai, Joji Mochida
Maintenance of autoantibody production in pristane-induced murine lupus
Shuhong Han, Haoyang Zhuang, Yuan Xu, Pui Lee, Yi Li, Joseph C. Wilson, Osvaldo Vidal, Hong Seok Choi, Yu Sun, Li-Jun Yang, Westley H. Reeves