Ausgabe 1/2019
Inhalt (302 Artikel)
Correction to: Green tea polyphenol treatment is chondroprotective, anti-inflammatory and palliative in a mouse posttraumatic osteoarthritis model
Daniel J. Leong, Marwa Choudhury, Regina Hanstein, David M. Hirsh, Sun Jin Kim, Robert J. Majeska, Mitchell B. Schaffler, John A. Hardin, David C. Spray, Mary B. Goldring, Neil J. Cobelli, Hui B. Sun
Safety and efficacy of infliximab in the treatment of refractory uveoretinitis in Behçet’s disease: a large-scale, long-term postmarketing surveillance in Japan
Shigeaki Ohno, Itsuro Umebayashi, Miyuki Matsukawa, Takashi Goto, Toshiro Yano
Altered composition and phenotype of mucosal-associated invariant T cells in early untreated rheumatoid arthritis
Hester Koppejan, Diahann T. S. L. Jansen, Marjolijn Hameetman, Ranjeny Thomas, Rene E. M. Toes, Floris A. van Gaalen
Prevalence and development of hip and knee osteoarthritis according to American College of Rheumatology criteria in the CHECK cohort
Jurgen Damen, Rogier M. van Rijn, Pieter J. Emans, Willem K. H. A. Hilberdink, Janet Wesseling, Edwin H. G. Oei, Sita M. A. Bierma-Zeinstra
The circadian regulator Bmal1 in joint mesenchymal cells regulates both joint development and inflammatory arthritis
Laura E. Hand, Suzanna H. Dickson, Anthony J. Freemont, David W. Ray, Julie E. Gibbs
KCa1.1 and Kv1.3 channels regulate the interactions between fibroblast-like synoviocytes and T lymphocytes during rheumatoid arthritis
Mark R. Tanner, Michael W. Pennington, Satendra S. Chauhan, Teresina Laragione, Pércio S. Gulko, Christine Beeton
Regional grafting of autologous adipose tissue is effective in inducing prompt healing of indolent digital ulcers in patients with systemic sclerosis: results of a monocentric randomized controlled study
Nicoletta Del Papa, Gabriele Di Luca, Romina Andracco, Eleonora Zaccara, Wanda Maglione, Francesca Pignataro, Antonina Minniti, Claudio Vitali
Efficacy and safety during extended treatment of lesinurad in combination with febuxostat in patients with tophaceous gout: CRYSTAL extension study
Nicola Dalbeth, Graeme Jones, Robert Terkeltaub, Dinesh Khanna, Maple Fung, Scott Baumgartner, Fernando Perez-Ruiz
Increased neutrophil extracellular traps activate NLRP3 and inflammatory macrophages in adult-onset Still’s disease
Qiongyi Hu, Hui Shi, Ting Zeng, Honglei Liu, Yutong Su, Xiaobing Cheng, Junna Ye, Yufeng Yin, Mengru Liu, Hui Zheng, Xinyao Wu, Huihui Chi, Zhuochao Zhou, Jinchao Jia, Yue Sun, Jialin Teng, Chengde Yang
Elevated plasma level of soluble triggering receptor expressed on myeloid cells-1 is associated with inflammation activity and is a potential biomarker of thrombosis in primary antiphospholipid syndrome
Yonatan Edel, Vitaly Kliminski, Elisheva Pokroy-Shapira, Shirly Oren, Ariela Dortort Lazar, Yael Pri-Paz Basson, Mohammad Egbaria, Yair Molad
Non-inferiority of dose reduction versus standard dosing of TNF-inhibitors in axial spondyloarthritis
Jordi Gratacós, Caridad Pontes, Xavier Juanola, Jesús Sanz, Ferran Torres, Cristina Avendaño, Antoni Vallano, Gonzalo Calvo, Eugenio de Miguel, Raimon Sanmartí, Miriam Almirall, Maria Aparicio, Agustí Sellas, Roser Vives, Nestor Albiñana, Mireia Moreno, Teresa Clavaguera, Juan Carlos Torre-Alonso, Raúl Veroz, Carlos Rodríguez-Lozano, Luís Francisco Linares, Ana Urruticoechea, Eduardo Collantes, Rosa María Morlà, Dèlia Reina, Eduardo Cuende, Pedro Zarco, Maria Cruz Fernández-Espartero, Rosario García-Vicuña, Carlos Alberto Montilla, Alejandro Villalba, Dora Pascual, Cristina Campos, Antonio Juan, Rafael Ariza, Consuelo Díaz-Miguel, Manuel Maqueda, Maria Pilar Fernández-Dapica, Manuel Fernández-Prada, Enrique Batlle, Carlos González-Fernández, Rubén Queiro
Bradykinin 1 receptor blockade subdues systemic autoimmunity, renal inflammation, and blood pressure in murine lupus nephritis
Ling Qin, Yong Du, Huihua Ding, Anam Haque, John Hicks, Claudia Pedroza, Chandra Mohan
Interactions between serum urate-associated genetic variants and sex on gout risk: analysis of the UK Biobank
Ravi K. Narang, Ruth Topless, Murray Cadzow, Greg Gamble, Lisa K. Stamp, Tony R. Merriman, Nicola Dalbeth
Significant association between joint ultrasonographic parameters and synovial inflammatory factors in rheumatoid arthritis
Yasushi Kondo, Katsuya Suzuki, Yumiko Inoue, Koumei Sakata, Chihiro Takahashi, Masaru Takeshita, Yoshiaki Kassai, Takahiro Miyazaki, Rimpei Morita, Yasuo Niki, Yuko Kaneko, Hidekata Yasuoka, Kunihiro Yamaoka, Akihiko Yoshimura, Tsutomu Takeuchi
Common mechanisms and holistic care in atherosclerosis and osteoporosis
Zoltán Szekanecz, Hennie G. Raterman, Zsófia Pethő, Willem F. Lems
The oncoprotein TBX3 is controlling severity in experimental arthritis
Samra Sardar, Alish Kerr, Daniëlle Vaartjes, Emilie Riis Moltved, Edita Karosiene, Ramneek Gupta, Åsa Andersson
Weight loss improves disease activity in patients with psoriatic arthritis and obesity: an interventional study
Eva Klingberg, Annelie Bilberg, Sofia Björkman, Martin Hedberg, Lennart Jacobsson, Helena Forsblad-d’Elia, Hans Carlsten, Björn Eliasson, Ingrid Larsson
Impairment of glyoxalase-1, an advanced glycation end-product detoxifying enzyme, induced by inflammation in age-related osteoarthritis
Sabine Trellu, Alice Courties, Stéphane Jaisson, Laëtitia Gorisse, Philippe Gillery, Saadia Kerdine-Römer, Carlos Vaamonde-Garcia, Xavier Houard, François-Paul Ekhirch, Alain Sautet, Bertrand Friguet, Claire Jacques, Francis Berenbaum, Jérémie Sellam
Vitamin D protects podocytes from autoantibodies induced injury in lupus nephritis by reducing aberrant autophagy
Qi Yu, Yingjin Qiao, Dongwei Liu, Fengxun Liu, Congcong Gao, Jiayu Duan, Lulu Liang, Xueqi Di, Yi Yuan, Yukui Gao, Siwan Cui, Yilu Qin, Tianfang Li, Zhaohui Zheng, Zhangsuo Liu
Correction to: The association between sonographic enthesitis and radiographic damage in psoriatic arthritis
Ari Polachek, Richard Cook, Vinod Chandran, Dafna D. Gladman, Lihi Eder
The value of the simplified RAMRIS-5 in early RA patients under methotrexate therapy using high-field MRI
Miriam Frenken, Christoph Schleich, Ralph Brinks, Daniel Benjamin Abrar, Christine Goertz, Matthias Schneider, Benedikt Ostendorf, Philipp Sewerin
Association between IL23R and ERAP1 polymorphisms and sacroiliac or spinal MRI inflammation in spondyloarthritis: DESIR cohort data
Adeline Ruyssen-Witrand, Cécile Luxembourger, Alain Cantagrel, Delphine Nigon, Pascal Claudepierre, Yannick Degboe, Arnaud Constantin
Minimal Clinically Important Differences for the Modified Rodnan Skin Score: Results from the Scleroderma Lung Studies (SLS-I and SLS-II)
Dinesh Khanna, Philip J. Clements, Elizabeth R. Volkmann, Holly Wilhalme, Chi-hong Tseng, Daniel E. Furst, Michael D. Roth, Oliver Distler, Donald P. Tashkin
Value of contrast-enhanced ultrasonography of the carotid artery for evaluating disease activity in Takayasu arteritis
Ling-Ying Ma, Chao-Lun Li, Li-Li Ma, Xiao-Meng Cui, Xiao-Min Dai, Ying Sun, Hui-Yong Chen, Bei-Jian Huang, Lin-Di Jiang
Time to minimal disease activity in relation to quality of life, productivity, and radiographic damage 1 year after diagnosis in psoriatic arthritis
Kim Wervers, Jolanda J. Luime, Ilja Tchetverikov, Andreas H. Gerards, Marc R. Kok, Cathelijne W. Y. Appels, Wiebo L. van der Graaff, Johannes H. L. M. van Groenendael, Lindy-Anne Korswagen, Josien J. Veris-van Dieren, Johanna M. W. Hazes, Marijn Vis
Synovial fluid monocyte/macrophage subsets and their correlation to patient-reported outcomes in osteoarthritic patients: a cohort study
Alejandro Gómez-Aristizábal, Rajiv Gandhi, Nizar N. Mahomed, K. Wayne Marshall, Sowmya Viswanathan
Association between severity of periodontitis and clinical activity in rheumatoid arthritis patients: a case–control study
Beatriz Rodríguez-Lozano, Jerián González-Febles, Jorge Luis Garnier-Rodríguez, Shashi Dadlani, Sagrario Bustabad-Reyes, Mariano Sanz, Fernando Sánchez-Alonso, Carlos Sánchez-Piedra, Enrique González-Dávila, Federico Díaz-González
In rheumatoid arthritis, changes in autoantibody levels reflect intensity of immunosuppression, not subsequent treatment response
Emma C. de Moel, Veerle F. A. M. Derksen, Leendert A. Trouw, Holger Bang, Gerard Collée, Leroy R. Lard, Sofia Ramiro, Tom W. J. Huizinga, Cornelia F. Allaart, René E. M. Toes, Diane van der Woude
Cytosolic group IVA phospholipase A2 inhibitors, AVX001 and AVX002, ameliorate collagen-induced arthritis
A. J. Feuerherm, E. A. Dennis, B. Johansen
CD34-selected versus unmanipulated autologous haematopoietic stem cell transplantation in the treatment of severe systemic sclerosis: a post hoc analysis of a phase I/II clinical trial conducted in Japan
Masahiro Ayano, Hiroshi Tsukamoto, Hiroki Mitoma, Yasutaka Kimoto, Mitsuteru Akahoshi, Yojiro Arinobu, Toshihiro Miyamoto, Takahiko Horiuchi, Hiroaki Niiro, Koji Nagafuji, Mine Harada, Koichi Akashi
Clinical course and prognostic factors of childhood Takayasu’s arteritis: over 15-year comprehensive analysis of 101 patients
Luyun Fan, Huimin Zhang, Jun Cai, Lirui Yang, Bin Liu, Dongmei Wei, Jiachen Yu, Jiali Fan, Lei Song, Wenjun Ma, Xianliang Zhou, Haiying Wu, Ying Lou
The need for comparative data in spondyloarthritis
Ernest Choy, Xenofon Baraliakos, Frank Behrens, Salvatore D’Angelo, Kurt de Vlam, Bruce W. Kirkham, Mikkel Østergaard, Georg A. Schett, Michael Rissler, Kamel Chaouche-Teyara, Chiara Perella
Awareness and perceived risk of cardiovascular disease among individuals living with rheumatoid arthritis is low: results of a systematic literature review
Olivia R. Ghosh-Swaby, Bindee Kuriya
Endothelial activation and injury by microparticles in patients with systemic lupus erythematosus and rheumatoid arthritis
Laura Atehortúa, Mauricio Rojas, Gloria Vásquez, Carlos H. Muñoz-Vahos, Adriana Vanegas-García, Rafael Andrés Posada-Duque, Diana Castaño
Classification, categorization and essential items for digital ulcer evaluation in systemic sclerosis: a DeSScipher/European Scleroderma Trials and Research group (EUSTAR) survey
J. Blagojevic, S. Bellando-Randone, G. Abignano, J. Avouac, L. Cometi, L. Czirják, C. P. Denton, O. Distler, M. Frerix, S. Guiducci, D. Huscher, V. K. Jaeger, V. Lóránd, B. Maurer, S. Nihtyanova, G. Riemekasten, E. Siegert, I. H. Tarner, S. Vettori, U. A. Walker, Y. Allanore, U. Müller-Ladner, F. Del Galdo, M. Matucci-Cerinic
Self-reported sleep quality and sleep disorders in people with physician-diagnosed gout: an Internet cross-sectional survey
Jasvinder A. Singh
Ixekizumab and complete resolution of enthesitis and dactylitis: integrated analysis of two phase 3 randomized trials in psoriatic arthritis
Dafna D. Gladman, Ana-Maria Orbai, Uta Klitz, James Cheng-Chung Wei, Gaia Gallo, Julie Birt, Suchitrita Rathmann, David Shrom, Helena Marzo-Ortega
Reduction of autophagy and increase in apoptosis correlates with a favorable clinical outcome in patients with rheumatoid arthritis treated with anti-TNF drugs
M. Vomero, V. Manganelli, C. Barbati, T. Colasanti, A. Capozzi, A. Finucci, F. R. Spinelli, F. Ceccarelli, C. Perricone, S. Truglia, S. Morrone, R. Maggio, R. Misasi, M. Bombardieri, M. Di Franco, F. Conti, M. Sorice, G. Valesini, C. Alessandri
Reversible SAHH inhibitor protects against glomerulonephritis in lupus-prone mice by downregulating renal α-actinin-4 expression and stabilizing integrin-cytoskeleton linkage
Shijun He, Xing Liu, Zemin Lin, Yuting Liu, Lei Gu, Hu Zhou, Wei Tang, Jianping Zuo
Psychometric validation of the EuroQoL 5-dimension (EQ-5D) questionnaire in patients with spondyloarthritis
Helen Hoi Lun Tsang, Jason Pui Yin Cheung, Carlos King Ho Wong, Prudence Wing Hang Cheung, Chak Sing Lau, Ho Yin Chung
Upregulation of miR-107 expression following hyperbaric oxygen treatment suppresses HMGB1/RAGE signaling in degenerated human nucleus pulposus cells
Chi-Chien Niu, Song-Shu Lin, Li-Jen Yuan, Meng-Ling Lu, Steve W. N. Ueng, Chuen-Yung Yang, Tsung-Ting Tsai, Po-Liang Lai
IgG4:IgG RNA ratio differentiates active disease from remission in granulomatosis with polyangiitis: a new disease activity marker? A cross-sectional and longitudinal study
A. Al-Soudi, M. E. Doorenspleet, R. E. Esveldt, L. T. Burgemeister, A. E. Hak, B. J. H. van den Born, S. W. Tas, R. F. van Vollenhoven, P. L. Klarenbeek, N. de Vries
Differences and similarities between IgG4-related disease with and without dacryoadenitis and sialoadenitis: clinical manifestations and treatment efficacy
Mu Wang, Panpan Zhang, Wei Lin, Yunyun Fei, Hua Chen, Jing Li, Li Zhang, Wenjie Zheng, Yongze Li, Xiaofeng Zeng, Jiaxin Zhou, Yamin Lai, Xiaowei Liu, Huadan Xue, Yueying Cui, Lian Zhou, Jizhi Zhao, Wen Zhang
Anti-citrullinated protein antibodies are associated with osteopenia but not with pain at diagnosis of rheumatoid arthritis: data from the BARFOT cohort
Ingiäld Hafström, Sofia Ajeganova, Kristina Forslind, Björn Svensson
Tolerogenic XCR1+ dendritic cell population is dysregulated in HLA-B27 transgenic rat model of spondyloarthritis
Kétia Ermoza, Simon Glatigny, Nadège Jah, Vânia Camilo, Hendrick Mambu Mambueni, Luiza M. Araujo, Gilles Chiocchia, Maxime Breban
Rheumatoid arthritis reprograms circadian output pathways
Toryn M. Poolman, Julie Gibbs, Amy L. Walker, Suzanna Dickson, Laura Farrell, James Hensman, Alexandra C. Kendall, Robert Maidstone, Stacey Warwood, Andrew Loudon, Magnus Rattray, Ian N. Bruce, Anna Nicolaou, David W. Ray
New-onset non-infectious pulmonary manifestations among patients with systemic lupus erythematosus in Sweden
Lindsy J. Forbess, Marios Rossides, Michael H. Weisman, Julia F. Simard
Microbiome dysbiosis is associated with disease duration and increased inflammatory gene expression in systemic sclerosis skin
Michael E. Johnson, Jennifer M. Franks, Guoshuai Cai, Bhaven K. Mehta, Tammara A. Wood, Kimberly Archambault, Patricia A. Pioli, Robert W. Simms, Nicole Orzechowski, Sarah Arron, Michael L. Whitfield
Romidepsin suppresses monosodium urate crystal-induced cytokine production through upregulation of suppressor of cytokine signaling 1 expression
M. C. P. Cleophas, T. O. Crişan, V. Klück, N. Hoogerbrugge, R. T. Netea-Maier, C. A. Dinarello, M. G. Netea, L. A. B. Joosten
Deregulation of microRNA expression in monocytes and CD4+ T lymphocytes from patients with axial spondyloarthritis
Olivier Fogel, Andreas Bugge Tinggaard, Maud Fagny, Nelly Sigrist, Elodie Roche, Laurence Leclere, Jean-François Deleuze, Frederic Batteux, Maxime Dougados, Corinne Miceli-Richard, Jörg Tost
Exocrine pancreatic function is preserved in systemic sclerosis
Gracijela Bozovic, Rille Pullerits, Arne Ståhl, Kristina Ydström, Daniel Wenger, Jan Marsal, Pontus Thulin, Kristofer Andréasson
Adult-onset Still’s disease biological treatment strategy may depend on the phenotypic dichotomy
François Vercruysse, Thomas Barnetche, Estibaliz Lazaro, Emilie Shipley, François Lifermann, Alexandre Balageas, Xavier Delbrel, Bruno Fautrel, Christophe Richez, Thierry Schaeverbeke, Marie-Elise Truchetet
Efficacy of canakinumab as first-line biologic agent in adult-onset Still’s disease
Giulio Cavalli, Alessandro Tomelleri, Giacomo De Luca, Corrado Campochiaro, Charles A. Dinarello, Elena Baldissera, Lorenzo Dagna
Correction to: Clinical course and prognostic factors of childhood Takayasu’s arteritis: over 15-year comprehensive analysis of 101 patients
Luyun Fan, Huimin Zhang, Jun Cai, Lirui Yang, Bin Liu, Dongmei Wei, Jiachen Yu, Jiali Fan, Lei Song, Wenjun Ma, Xianliang Zhou, Haiying Wu, Ying Lou
What is the additional value of MRI of the foot to the hand in undifferentiated arthritis to predict rheumatoid arthritis development?
Y. J. Dakkak, D. M. Boeters, A. C. Boer, M. Reijnierse, A. H. M. van der Helm-van Mil
Significance of anti-neutrophil cytoplasmic antibodies in systemic sclerosis
Jayne Moxey, Molla Huq, Susanna Proudman, Joanne Sahhar, Gene-Siew Ngian, Jenny Walker, Gemma Strickland, Michelle Wilson, Laura Ross, Gabor Major, Janet Roddy, Wendy Stevens, Mandana Nikpour
Serum KL-6 levels reflect the severity of interstitial lung disease associated with connective tissue disease
Jeong Seok Lee, Eun Young Lee, You-Jung Ha, Eun Ha Kang, Yun Jong Lee, Yeong Wook Song
Do musculoskeletal ultrasound and magnetic resonance imaging identify synovitis and tenosynovitis at the same joints and tendons? A comparative study in early inflammatory arthritis and clinically suspect arthralgia
Sarah Ohrndorf, Aleid C. Boer, Debbie M. Boeters, Robin M. ten Brinck, Gerd-R. Burmester, Marion C. Kortekaas, Annette H. M. van der Helm-van Mil
Mass spectrometry-based analysis of cerebrospinal fluid from arthritis patients—immune-related candidate proteins affected by TNF blocking treatment
Johanna Estelius, Johan Lengqvist, Elena Ossipova, Helena Idborg, Erwan Le Maître, Magnus L. A. Andersson, Lou Brundin, Mohsen Khademi, Elisabet Svenungsson, Per-Johan Jakobsson, Jon Lampa
Health-related quality of life in systemic sclerosis compared with other rheumatic diseases: a cross-sectional study
Eun Hye Park, Vibeke Strand, Yoon Jeong Oh, Yeong Wook Song, Eun Bong Lee
Two subgroups in systemic lupus erythematosus with features of antiphospholipid or Sjögren’s syndrome differ in molecular signatures and treatment perspectives
Helena Idborg, Arash Zandian, Ann-Sofi Sandberg, Bo Nilsson, Kerstin Elvin, Lennart Truedsson, Azita Sohrabian, Johan Rönnelid, John Mo, Giorgia Grosso, Marika Kvarnström, Iva Gunnarsson, Janne Lehtiö, Peter Nilsson, Elisabet Svenungsson, Per-Johan Jakobsson
Similar alteration for mental and physical aspects in health-related quality of life over 5 to 8 years in 1347 patients with early arthritis and early inflammatory back pain
Déborah Puyraimond-Zemmour, Benjamin Granger, Anna Molto, Cécile Gaujoux-Viala, Francis Guillemin, Adeline Ruyssen-Witrand, Maxime Dougados, Bruno Fautrel, Laure Gossec
Health-related quality of life in patients with giant cell arteritis treated with tocilizumab in a phase 3 randomised controlled trial
Vibeke Strand, Sophie Dimonaco, Katie Tuckwell, Micki Klearman, Neil Collinson, John H. Stone
Response to: “A somatization comorbidity phenotype impacts response to therapy in rheumatoid arthritis: post hoc results from the certolizumab pegol phase 4 PREDICT trial”
Annelise Madison, Barbara L. Andersen, Ali Ajam
Association between concomitant csDMARDs and clinical response to TNF inhibitors in overweight patients with axial spondyloarthritis
Borja Hernández-Breijo, Chamaida Plasencia-Rodríguez, Victoria Navarro-Compán, Ana Martínez-Feito, Andrea Jochems, Eva L. Kneepkens, Gerrit J. Wolbink, Theo Rispens, Cristina Diego, Dora Pascual-Salcedo, Alejandro Balsa
Multisite pain and self-reported falls in older people: systematic review and meta-analysis
Victoria K. Welsh, Lorna E. Clarson, Christian D. Mallen, John McBeth
Combining naproxen and a dual amylin and calcitonin receptor agonist improves pain and structural outcomes in the collagen-induced arthritis rat model
Anna Katri, Aneta Dąbrowska, Henrik Löfvall, Ming Ding, Morten A. Karsdal, Kim V. Andreassen, Christian S. Thudium, Kim Henriksen
Correction to: Efficacy of canakinumab as first-line biologic agent in adult-onset Still’s disease
Giulio Cavalli, Alessandro Tomelleri, Giacomo De Luca, Corrado Campochiaro, Charles A. Dinarello, Elena Baldissera, Lorenzo Dagna
Full high-throughput sequencing analysis of differences in expression profiles of long noncoding RNAs and their mechanisms of action in systemic lupus erythematosus
Hui Ye, Xue Wang, Lei Wang, Xiaoying Chu, Xuanxuan Hu, Li Sun, Minghua Jiang, Hong Wang, Zihan Wang, Han Zhao, Xinyu Yang, Jianguang Wang
Invasive mycoses in patients with connective tissue disease from Southern China: clinical features and associated factors
Minxi Lao, Zhongping Zhan, Fan Su, Hao Li, Zheng Yang, Haihong Chen, Liuqin Liang, Dongying Chen
In vitro and in vivo assessment of the proresolutive and antiresorptive actions of resolvin D1: relevance to arthritis
Houda Abir Benabdoun, Merve Kulbay, Elsa-Patricia Rondon, Francis Vallières, Qin Shi, Julio Fernandes, Hassan Fahmi, Mohamed Benderdour
High serum uric acid level is associated with greater handgrip strength in the aged population
Jennifer Lee, Yeon Sik Hong, Sung-Hwan Park, Kwi Young Kang
Divergent roles of prostacyclin and PGE2 in human tendinopathy
Filip Bergqvist, Andrew J. Carr, Kim Wheway, Bridget Watkins, Udo Oppermann, Per-Johan Jakobsson, Stephanie G. Dakin
Impact of synthetic and biological immunomodulatory therapy on the duration of 17DD yellow fever vaccine-induced immunity in rheumatoid arthritis
Clarissa de Castro Ferreira, Ana Carolina Campi-Azevedo, Vanessa Peruhype-Magalhāes, Jordana Grazziela Coelho-dos-Reis, Lis Ribeiro do Valle Antonelli, Karen Torres, Larissa Chaves Freire, Ismael Artur da Costa-Rocha, Ana Cristina Vanderley Oliveira, Maria de Lourdes de Sousa Maia, Sheila Maria Barbosa de Lima, Carla Magda Domingues, Andréa Teixeira-Carvalho, Olindo Assis Martins-Filho, Lícia Maria Henrique da Mota
Role of lectin pathway complement proteins and genetic variants in organ damage and disease severity of systemic sclerosis: a cross-sectional study
Michael Osthoff, Veronika K. Jaeger, Ingmar A. F. M. Heijnen, Marten Trendelenburg, Suzana Jordan, Oliver Distler, Ulrich A. Walker
The impact of dysfunctional variants of ABCG2 on hyperuricemia and gout in pediatric-onset patients
Blanka Stiburkova, Katerina Pavelcova, Marketa Pavlikova, Pavel Ješina, Karel Pavelka
Hypoxia-induced miR-191-C/EBPβ signaling regulates cell proliferation and apoptosis of fibroblast-like synoviocytes from patients with rheumatoid arthritis
Shanshan Yu, Ying Lu, Ming Zong, Qi Tan, Lieying Fan
Sarilumab plus methotrexate in patients with active rheumatoid arthritis and inadequate response to methotrexate: results of a randomized, placebo-controlled phase III trial in Japan
Yoshiya Tanaka, Kazuteru Wada, Yoshinori Takahashi, Owen Hagino, Hubert van Hoogstraten, Neil M. H. Graham, Hideto Kameda
The Fatigue Assessment Scale as a simple and reliable tool in systemic lupus erythematosus: a cross-sectional study
Alice Horisberger, Delphine Courvoisier, Camillo Ribi
Cause or effect? Interpreting emerging evidence for dysbiosis in systemic sclerosis
Christopher P. Denton, Charles Murray
Incidence and survival impact of pulmonary arterial hypertension among patients with systemic lupus erythematosus: a nationwide cohort study
Hung-An Chen, Tsai-Ching Hsu, Su-Ching Yang, Chia-Tse Weng, Chun-Hsin Wu, Chien-Yao Sun, Chun-Yu Lin
Consequences of bariatric surgery on outcomes in rheumatic diseases
Eric Lespessailles, Emneh Hammoud, Hechmi Toumi, Nada Ibrahim-Nasser
An open-label extension study to demonstrate long-term safety and efficacy of ABP 501 in patients with rheumatoid arthritis
Stanley Cohen, Jose L. Pablos, Karel Pavelka, Gerard Anton Müller, Alan Matsumoto, Alan Kivitz, Hui Wang, Eswar Krishnan
Estradiol levels are elevated in older men with diffuse cutaneous SSc and are associated with decreased survival
DeAnna Baker Frost, Bethany Wolf, Christine Peoples, Jessica Fike, Katherine Silver, Maureen Laffoon, Thomas A. Medsger Jr, Carol Feghali-Bostwick
Survival and prognosis factors in systemic sclerosis: data of a French multicenter cohort, systematic review, and meta-analysis of the literature
M. R. Pokeerbux, J. Giovannelli, L. Dauchet, L. Mouthon, C. Agard, J. C. Lega, Y. Allanore, P. Jego, B. Bienvenu, S. Berthier, A. Mekinian, E. Hachulla, D. Launay
Inhibition of hexokinases holds potential as treatment strategy for rheumatoid arthritis
Guanhua Song, Qiqi Lu, Hua Fan, Xiumei Zhang, Luna Ge, Ruisong Tian, Shiguan Wang, Tingting Feng, Jihong Pan, Jingjing Feng, Yabo Xiao, Xin Yi, Ningxin Ren, Lin Wang
Withdrawal of infliximab therapy in ankylosing spondylitis in persistent clinical remission, results from the REMINEA study
Mireia Moreno, Jordi Gratacós, Vicenç Torrente-Segarra, Raimon Sanmarti, Rosa Morlà, Caridad Pontes, Maria Llop, Xavier Juanola, Arturo Rodriguez-de-la-Serna, Victoria Hernandez, Elena Riera, Vera Ortiz, Teresa Clavaguera, Patricia Reyner, Miquel Sala, Agustí Sellas, Concepció Pitarch, Delia Reina, Jordi Blanco, Montse Centelles, Ramon Figuls, Mario Gelman, Xavier Arasa, Maria Bonet, Manel Ciria
Safety and efficacy of tofacitinib for up to 9.5 years in the treatment of rheumatoid arthritis: final results of a global, open-label, long-term extension study
Jürgen Wollenhaupt, Eun-Bong Lee, Jeffrey R. Curtis, Joel Silverfield, Ketti Terry, Koshika Soma, Chris Mojcik, Ryan DeMasi, Sander Strengholt, Kenneth Kwok, Irina Lazariciu, Lisy Wang, Stanley Cohen
Synovial tissue biopsy analysis: unlocking the hidden secrets to personalised medicine?
Helen Michelle McGettrick
Drug tolerability and reasons for discontinuation of seven biologics in 4466 treatment courses of rheumatoid arthritis—the ANSWER cohort study
Kosuke Ebina, Motomu Hashimoto, Wataru Yamamoto, Toru Hirano, Ryota Hara, Masaki Katayama, Akira Onishi, Koji Nagai, Yonsu Son, Hideki Amuro, Keiichi Yamamoto, Yuichi Maeda, Koichi Murata, Sadao Jinno, Tohru Takeuchi, Makoto Hirao, Atsushi Kumanogoh, Hideki Yoshikawa
Iguratimod represses B cell terminal differentiation linked with the inhibition of PKC/EGR1 axis
Yan Ye, Mei Liu, Longhai Tang, Fang Du, Yuanhua Liu, Pei Hao, Qiong Fu, Qiang Guo, Qingran Yan, Xiaoming Zhang, Chunde Bao
A simplified lung ultrasound for the diagnosis of interstitial lung disease in connective tissue disease: a meta-analysis
Hai Qin Xie, Wei Wei Zhang, De Sheng Sun, Xiang Mei Chen, Shu Fang Yuan, Zheng Hua Gong, Li Liu
Gene expression analysis of vascular pathophysiology related to anti-TNF treatment in rheumatoid arthritis
Szilárd Póliska, Timea Besenyei, Edit Végh, Attila Hamar, Anita Pusztai, Andrea Váncsa, Nóra Bodnár, Szilvia Szamosi, Mária Csumita, György Kerekes, Zoltán Szabó, Zoltán Nagy, Gabriella Szűcs, Sándor Szántó, Gábor Zahuczky, László Nagy, Zoltán Szekanecz
Study of MRI brain findings and carotid US features in systemic sclerosis patients, relationship with disease parameters
Rania M. Gamal, Hanan Sayed M. Abozaid, Mohmed Zidan, Mohamed Aboel-Kassem F. Abdelmegid, Mohmed Raouf Abdel-Razek, Sahar Abdel-Rahman Alsayed, Amr F. Mourad, Nashwa Mostafa A. Azoz, Lobna Abdel-Wahid Mohram, Daniel E. Furst
Association between baseline clinical and imaging findings and the development of digital ulcers in patients with systemic sclerosis
S. Friedrich, S. Lüders, A. M. Glimm, S. G. Werner, G. Schmittat, G. R. Burmester, M. Backhaus, G. Riemekasten, S. Ohrndorf
Low back pain precedes the development of new knee pain in the elderly population; a novel predictive score from a longitudinal cohort study
Hiromu Ito, Shinjiro Tominari, Yasuharu Tabara, Takeo Nakayama, Moritoshi Furu, Tomotoshi Kawata, Masayuki Azukizawa, Kazuya Setoh, Takahisa Kawaguchi, Fumihiko Matsuda, Shuichi Matsuda, Yasuharu Tabara, Takahisa Kawaguchi, Kazuya Setoh, Yoshimitsu Takahashi, Shinji Kosugi, Takeo Nakayama, Fumihiko Matsuda
MicroRNA-143-5p targeting eEF2 gene mediates intervertebral disc degeneration through the AMPK signaling pathway
Qi Yang, Xiao-Peng Guo, Yan-Li Cheng, Yang Wang
Correction to: Sarilumab plus methotrexate in patients with active rheumatoid arthritis and inadequate response to methotrexate: results of a randomized, placebo-controlled phase III trial in Japan
Yoshiya Tanaka, Kazuteru Wada, Yoshinori Takahashi, Owen Hagino, Hubert van Hoogstraten, Neil M. H. Graham, Hideto Kameda
The agreement between ultrasound-determined joint inflammation and clinical signs in patients with rheumatoid arthritis
Xiaoying Sun, Xuerong Deng, Wenhui Xie, Liujun Wang, Yu Wang, Zhuoli Zhang
Efficacy and safety of namilumab, a human monoclonal antibody against granulocyte-macrophage colony-stimulating factor (GM-CSF) ligand in patients with rheumatoid arthritis (RA) with either an inadequate response to background methotrexate therapy or an inadequate response or intolerance to an anti-TNF (tumour necrosis factor) biologic therapy: a randomized, controlled trial
Peter C. Taylor, Didier Saurigny, Jiri Vencovsky, Tsutomu Takeuchi, Tadashi Nakamura, Galina Matsievskaia, Barbara Hunt, Thomas Wagner, Bernard Souberbielle
Evaluation of pneumococcal and tetanus vaccine responses in patients with rheumatoid arthritis receiving baricitinib: results from a long-term extension trial substudy
Kevin L. Winthrop, Clifton O. Bingham III, Wendy J. Komocsar, John Bradley, Maher Issa, Rena Klar, Cynthia E. Kartman
Antifibrotic effects of 2-carba cyclic phosphatidic acid (2ccPA) in systemic sclerosis: contribution to the novel treatment
Tomoaki Higuchi, Kae Takagi, Akiko Tochimoto, Yuki Ichimura, Takanari Norose, Yasuhiro Katsumata, Ikuko Masuda, Hisashi Yamanaka, Toshiro Morohoshi, Yasushi Kawaguchi
Effects of a footwear intervention on foot pain and disability in people with gout: a randomised controlled trial
Mike Frecklington, Nicola Dalbeth, Peter McNair, Trish Morpeth, Alain C. Vandal, Peter Gow, Keith Rome
Baicalein ameliorates pristane-induced lupus nephritis via activating Nrf2/HO-1 in myeloid-derived suppressor cells
Dan Li, Guoping Shi, Jiali Wang, Dongya Zhang, Yuchen Pan, Huan Dou, Yayi Hou
Autologous hematopoietic stem cell transplantation in systemic sclerosis induces long-lasting changes in B cell homeostasis toward an anti-inflammatory B cell cytokine pattern
Michael Gernert, Hans-Peter Tony, Eva Christina Schwaneck, Ottar Gadeholt, Marc Schmalzing
High levels of circulating interferons type I, type II and type III associate with distinct clinical features of active systemic lupus erythematosus
Vilija Oke, Iva Gunnarsson, Jessica Dorschner, Susanna Eketjäll, Agneta Zickert, Timothy B. Niewold, Elisabet Svenungsson
Increased peptidylarginine deiminases expression during the macrophage differentiation and participated inflammatory responses
Ning-Sheng Lai, Hui-Chun Yu, Chien-Hsueh Tung, Kuang-Yung Huang, Hsien-Bin Huang, Ming-Chi Lu
Ipriflavone attenuates the degeneration of cartilage by blocking the Indian hedgehog pathway
Li Guo, Xiaochun Wei, Zhiwei Zhang, Xiaojian Wang, Chunli Wang, Pengcui Li, Chunfang Wang, Lei Wei
Low plasma concentrations of apolipoprotein M are associated with disease activity and endothelial dysfunction in systemic lupus erythematosus
Helena Tydén, Christian Lood, Andreas Jönsen, Birgitta Gullstrand, Robin Kahn, Petrus Linge, Sunil B. Kumaraswamy, Björn Dahlbäck, Anders A. Bengtsson
Long-term safety of secukinumab in patients with moderate-to-severe plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis: integrated pooled clinical trial and post-marketing surveillance data
A. Deodhar, P. J. Mease, I. B. McInnes, X. Baraliakos, K. Reich, A. Blauvelt, C. Leonardi, B. Porter, A. Das Gupta, A. Widmer, L. Pricop, T. Fox
RNA sequencing of mesenchymal stem cells reveals a blocking of differentiation and immunomodulatory activities under inflammatory conditions in rheumatoid arthritis patients
Jose Ramon Lamas, Benjamin Fernandez-Gutierrez, Arkaitz Mucientes, Fernando Marco, Yaiza Lopiz, Juan Angel Jover, Lydia Abasolo, Luis Rodríguez-Rodríguez
Symptomatic bone marrow lesions induced by reduced bone mineral density in middle-aged women: a cross-sectional Japanese population study
Seiya Ota, Daisuke Chiba, Eiji Sasaki, Gentaro Kumagai, Yuji Yamamoto, Shigeyuki Nakaji, Eiichi Tsuda, Yasuyuki Ishibashi
Correction to: Drug tolerability and reasons for discontinuation of seven biologics in 4466 treatment courses of rheumatoid arthritis—the ANSWER cohort study
Kosuke Ebina, Motomu Hashimoto, Wataru Yamamoto, Toru Hirano, Ryota Hara, Masaki Katayama, Akira Onishi, Koji Nagai, Yonsu Son, Hideki Amuro, Keiichi Yamamoto, Yuichi Maeda, Koichi Murata, Sadao Jinno, Tohru Takeuchi, Makoto Hirao, Atsushi Kumanogoh, Hideki Yoshikawa
Does treatment strategy influence the ability to achieve and sustain DMARD-free remission in patients with RA? Results of an observational study comparing an intensified DAS-steered treatment strategy with treat to target in routine care
L. E. Burgers, J. A. van der Pol, T. W. J. Huizinga, C. F. Allaart, A. H. M. van der Helm-van Mil
Differential synovial tissue biomarkers among psoriatic arthritis and rheumatoid factor/anti-citrulline antibody-negative rheumatoid arthritis
Stefano Alivernini, Dario Bruno, Barbara Tolusso, Laura Bui, Luca Petricca, Maria Rita Gigante, Domenico Birra, Anna Laura Fedele, Giusy Peluso, Francesco Federico, Gianfranco Ferraccioli, Elisa Gremese
Point-of-care uric acid testing is useful in routine clinical care of gout
Philip L. Riches, Kristen Sing, Kathryn Berg
Long-term experience with apremilast in patients with psoriatic arthritis: 5-year results from a PALACE 1–3 pooled analysis
Arthur Kavanaugh, Dafna D. Gladman, Christopher J. Edwards, Georg Schett, Benoit Guerette, Nikolay Delev, Lichen Teng, Maria Paris, Philip J. Mease
Performance of 18F-sodium fluoride positron emission tomography with computed tomography to assess inflammatory and structural sacroiliitis on magnetic resonance imaging and computed tomography, respectively, in axial spondyloarthritis
Marie Raynal, Fehd Bouderraoui, Remy Ouichka, Julian Melchior, Olivier Morel, Alain Blum, Isabelle Chary-Valckenaere, Willy Ngueyon Sime, Véronique Roch, Walter Maksymowych, Robert G. Lambert, Pierre Olivier, Damien Loeuille
Effects of intensity of electroacupuncture on chronic pain in patients with knee osteoarthritis: a randomized controlled trial
Zheng-tao Lv, Lin-lin Shen, Bing Zhu, Zhao-qing Zhang, Chao-yang Ma, Guo-fu Huang, Jing Yin, Ling-ling Yu, Si-yi Yu, Ming-qiao Ding, Jing Li, Xiao-cui Yuan, Wei He, Xiang-hong Jing, Man Li
ACPA-negative RA consists of subgroups: patients with high likelihood of achieving sustained DMARD-free remission can be identified by serological markers at disease presentation
Debbie M. Boeters, Leonie E. Burgers, Eric H. Sasso, Tom W. J. Huizinga, Annette H. M. van der Helm – van Mil
Long-term efficacy, safety and immunogenicity in patients with rheumatoid arthritis continuing on an etanercept biosimilar (LBEC0101) or switching from reference etanercept to LBEC0101: an open-label extension of a phase III multicentre, randomised, double-blind, parallel-group study
Min-Chan Park, Hiroaki Matsuno, Jinseok Kim, Sung-Hwan Park, Sang-Heon Lee, Yong-Beom Park, Yun Jong Lee, Sang-Il Lee, Won Park, Dong Hyuk Sheen, Jung-Yoon Choe, Chan-Bum Choi, Seung-Jae Hong, Chang-Hee Suh, Shin-Seok Lee, Hoon-Suk Cha, Bin Yoo, Jin-Wuk Hur, Geun-Tae Kim, Wan-Hee Yoo, Han Joo Baek, Kichul Shin, Seung Cheol Shim, Hyung-In Yang, Hyun Ah Kim, Kyung-Su Park, In Ah Choi, Jisoo Lee, Masato Tomomitsu, Seonghye Shin, Jiyoon Lee, Yeong Wook Song
Cysteine-rich 61 (Cyr61): a biomarker reflecting disease activity in rheumatoid arthritis
Yong Fan, Xinlei Yang, Juan Zhao, Xiaoying Sun, Wenhui Xie, Yanrong Huang, Guangtao Li, Yanjie Hao, Zhuoli Zhang
Distinct fatty acid signatures in infrapatellar fat pad and synovial fluid of patients with osteoarthritis versus rheumatoid arthritis
Anne-Mari Mustonen, Reijo Käkelä, Petri Lehenkari, Johanna Huhtakangas, Sanna Turunen, Antti Joukainen, Tommi Kääriäinen, Tommi Paakkonen, Heikki Kröger, Petteri Nieminen
Etanercept treatment for extended oligoarticular juvenile idiopathic arthritis, enthesitis-related arthritis, or psoriatic arthritis: 6-year efficacy and safety data from an open-label trial
Ivan Foeldvari, Tamàs Constantin, Jelena Vojinović, Gerd Horneff, Vyacheslav Chasnyk, Joke Dehoorne, Violeta Panaviene, Gordana Sušić, Valda Stanevicha, Katarzyna Kobusinska, Zbigniew Zuber, Bogna Dobrzyniecka, Irina Nikishina, Brigitte Bader-Meunier, Luciana Breda, Pavla Doležalová, Chantal Job-Deslandre, Ingrida Rumba-Rozenfelde, Nico Wulffraat, Ronald D. Pedersen, Jack F. Bukowski, Bonnie Vlahos, Alberto Martini, Nicolino Ruperto
Incorporation of the anteroposterior lumbar radiographs in the modified Stoke Ankylosing Spondylitis Spine Score improves detection of radiographic spinal progression in axial spondyloarthritis
Maria Llop, Valeria Rios Rodriguez, Imke Redeker, Joachim Sieper, Hildrun Haibel, Martin Rudwaleit, Denis Poddubnyy
Association between metformin use and disease progression in obese people with knee osteoarthritis: data from the Osteoarthritis Initiative—a prospective cohort study
Yuanyuan Wang, Sultana Monira Hussain, Anita E. Wluka, Yuan Z. Lim, François Abram, Jean-Pierre Pelletier, Johanne Martel-Pelletier, Flavia M. Cicuttini
Biological treatment of ankylosing spondylitis: a nationwide study of treatment trajectories on a patient level in clinical practice
Ulf Lindström, Tor Olofsson, Sara Wedrén, Ilia Qirjazo, Johan Askling
Skin thickness score as a surrogate marker of organ involvements in systemic sclerosis: a retrospective observational study
Kazuki M. Matsuda, Ayumi Yoshizaki, Ai Kuzumi, Takemichi Fukasawa, Satoshi Ebata, Shunsuke Miura, Tetsuo Toyama, Asako Yoshizaki, Hayakazu Sumida, Yoshihide Asano, Koji Oba, Shinichi Sato
Switch from reference etanercept to SDZ ETN, an etanercept biosimilar, does not impact efficacy, safety, and immunogenicity of etanercept in patients with moderate-to-severe rheumatoid arthritis: 48-week results from the phase III, randomized, double-blind EQUIRA study
Janusz Jaworski, Marco Matucci-Cerinic, Hendrik Schulze-Koops, Maya H. Buch, Eugeniusz J. Kucharz, Yannick Allanore, Arthur Kavanaugh, Philip Young, Goran Babic
The RIG-I pathway is involved in peripheral T cell lymphopenia in patients with dermatomyositis
Lu Zhang, Qisheng Xia, Wenli Li, Qinglin Peng, Hanbo Yang, Xin Lu, Guochun Wang
Gout, flares, and allopurinol use: a population-based study
Charlotte Proudman, Susan E. Lester, David A. Gonzalez-Chica, Tiffany K. Gill, Nicola Dalbeth, Catherine L. Hill
Best practices in DNA methylation: lessons from inflammatory bowel disease, psoriasis and ankylosing spondylitis
Jessica M. Whyte, Jonathan J. Ellis, Matthew A. Brown, Tony J. Kenna
miR-449a inhibits cell proliferation, migration, and inflammation by regulating high-mobility group box protein 1 and forms a mutual inhibition loop with Yin Yang 1 in rheumatoid arthritis fibroblast-like synoviocytes
Yongsong Cai, Congshan Jiang, Jialin Zhu, Ke Xu, Xiaoyu Ren, Lin Xu, Peijing Hu, Bo Wang, Qiling Yuan, Yuanxu Guo, Jian Sun, Peng Xu, Yusheng Qiu
Targeting inflammatory pathways in axial spondyloarthritis
Daniel E. Furst, James S. Louie
Metformin improves salivary gland inflammation and hypofunction in murine Sjögren’s syndrome
Ji-Won Kim, Sung-Min Kim, Jin-Sil Park, Sun-Hee Hwang, JeongWon Choi, Kyung-Ah Jung, Jun-Geol Ryu, Seon-Yeong Lee, Seung-Ki Kwok, Mi-La Cho, Sung-Hwan Park
Haploinsufficiency of A20 caused by a novel nonsense variant or entire deletion of TNFAIP3 is clinically distinct from Behçet’s disease
Naomi Tsuchida, Yohei Kirino, Yutaro Soejima, Masafumi Onodera, Katsuhiro Arai, Eiichiro Tamura, Takashi Ishikawa, Toshinao Kawai, Toru Uchiyama, Shigeru Nomura, Daisuke Kobayashi, Masataka Taguri, Satomi Mitsuhashi, Takeshi Mizuguchi, Atsushi Takata, Noriko Miyake, Hideaki Nakajima, Satoko Miyatake, Naomichi Matsumoto
Persistence rates of abatacept and TNF inhibitors used as first or second biologic DMARDs in the treatment of rheumatoid arthritis: 9 years of experience from the Rhumadata® clinical database and registry
Denis Choquette, Louis Bessette, Evo Alemao, Boulos Haraoui, Roelien Postema, Jean-Pierre Raynauld, Louis Coupal
Evaluation of concomitant peripheral arthritis in patients with recent onset axial spondyloarthritis: 5-year results from the DESIR cohort
Clementina López-Medina, Maxime Dougados, Adeline Ruyssen-Witrand, Anna Moltó
Outcome of patients with early arthritis without rheumatoid factor and ACPA and predictors of rheumatoid arthritis in the ESPOIR cohort
Gaël Mouterde, Nathalie Rincheval, Cédric Lukas, Claire Daien, Alain Saraux, Philippe Dieudé, Jacques Morel, Bernard Combe
Safety of abatacept compared with other biologic and conventional synthetic disease-modifying antirheumatic drugs in patients with rheumatoid arthritis: data from an observational study
Gulsen Ozen, Sofia Pedro, Rebecca Schumacher, Teresa A. Simon, Kaleb Michaud
Spinal radiographic progression over 2 years in ankylosing spondylitis patients treated with secukinumab: a historical cohort comparison
J. Braun, H. Haibel, M. de Hooge, R. Landewé, M. Rudwaleit, T. Fox, A. Readie, H. B. Richards, B. Porter, R. Martin, D. Poddubnyy, J. Sieper, D. van der Heijde
Depletion of activated macrophages with a folate receptor-beta-specific antibody improves symptoms in mouse models of rheumatoid arthritis
Yingwen Hu, Bingbing Wang, Jiayin Shen, Stewart A. Low, Karson S. Putt, Hans W. M. Niessen, Eric L. Matteson, Linda Murphy, Clemens Ruppert, Gerrit Jansen, Stephen J. Oliver, Yang Feng, Dimiter S. Dimitrov, Cheryl Nickerson-Nutter, Philip S. Low
The activin-follistatin anti-inflammatory cycle is deregulated in synovial fibroblasts
Magnus Diller, Klaus Frommer, Berno Dankbar, Ingo Tarner, Marie-Lisa Hülser, Lali Tsiklauri, Rebecca Hasseli, Michael Sauerbier, Thomas Pap, Stefan Rehart, Ulf Müller-Ladner, Elena Neumann
Calorie restriction with regular chow, but not a high-fat diet, delays onset of spontaneous osteoarthritis in the Hartley guinea pig model
Lauren B. Radakovich, Angela J. Marolf, Lauren A. Culver, Kelly S. Santangelo
Synovial fluid biomarkers associated with osteoarthritis severity reflect macrophage and neutrophil related inflammation
Collin A. Haraden, Janet L. Huebner, Ming-Feng Hsueh, Yi-Ju Li, Virginia Byers Kraus
Type I interferon in patients with systemic autoimmune rheumatic disease is associated with haematological abnormalities and specific autoantibody profiles
John A. Reynolds, Tracy A. Briggs, Gillian I. Rice, Sathya Darmalinggam, Vincent Bondet, Ellen Bruce, Mumtaz Khan, Sahena Haque, Hector Chinoy, Ariane L. Herrick, Eoghan M. McCarthy, Leo Zeef, Andrew Hayes, Darragh Duffy, Ben Parker, Ian N. Bruce
Testing the effects of gentle vibrotactile stimulation on symptom relief in fibromyalgia
Jesus Pujol, Daniel Ramos-López, Laura Blanco-Hinojo, Guillem Pujol, Héctor Ortiz, Gerard Martínez-Vilavella, Josep Blanch, Jordi Monfort, Joan Deus
Expression analysis of the osteoarthritis genetic susceptibility mapping to the matrix Gla protein gene MGP
Colin Shepherd, Abigail E. Reese, Louise N. Reynard, John Loughlin
Concurrent validity of provisional remission criteria for gout: a dual-energy CT study
Nicola Dalbeth, Christopher Frampton, Maple Fung, Scott Baumgartner, Savvas Nicolaou, Hyon K. Choi
Comparative study of corticosteroid monotherapy, and TNF inhibitors with or without corticosteroid in patients with refractory entero-Behcet’s disease
Ippei Miyagawa, Kazuhisa Nakano, Shigeru Iwata, Shingo Nakayamada, Kazuyoshi Saito, Kentaro Hanami, Shunsuke Fukuyo, Satoshi Kubo, Akio Kawabe, Yusuke Miyazaki, Yoshiya Tanaka
Antibodies against specific extractable nuclear antigens (ENAs) as diagnostic and prognostic tools and inducers of a profibrotic phenotype in cultured human skin fibroblasts: are they functional?
Claudio Corallo, Sara Cheleschi, Maurizio Cutolo, Stefano Soldano, Antonella Fioravanti, Nila Volpi, Daniela Franci, Ranuccio Nuti, Nicola Giordano
A novel function of artesunate on inhibiting migration and invasion of fibroblast-like synoviocytes from rheumatoid arthritis patients
Jian-Da Ma, Jun Jing, Jun-Wei Wang, Tao Yan, Qian-Hua Li, Ying-Qian Mo, Dong-Hui Zheng, Jin-Long Gao, Ky-Anh Nguyen, Lie Dai
Survival and death causes of patients with giant cell arteritis in Western Norway 1972–2012: a retrospective cohort study
L. K. Brekke, B.-T. S. Fevang, A. P. Diamantopoulos, J. Assmus, E. Esperø, C. G. Gjesdal
Health service utilization among African American women living with systemic lupus erythematosus: perceived impacts of a self-management intervention
Abena A. Twumasi, Anna Shao, Charmayne Dunlop-Thomas, Cristina Drenkard, Hannah L. F. Cooper
Juvenile idiopathic arthritis associated with a mutation in GATA3
Anna E. Patrick, Wei Wang, Elly Brokamp, Thomas Brent Graham, Thomas M. Aune, Jessica B. Duis
Higher baseline global leukocyte DNA methylation is associated with MTX non-response in early RA patients
Helen R. Gosselt, Bertrand D. van Zelst, Maurits C. F. J. de Rotte, Johanna M. W. Hazes, Robert de Jonge, Sandra G. Heil
Hand exercise for women with rheumatoid arthritis and decreased hand function: an exploratory randomized controlled trial
Karen Ellegaard, Cecilie von Bülow, Alice Røpke, Cecilie Bartholdy, Inge Skovby Hansen, Signe Rifbjerg-Madsen, Marius Henriksen, Eva Ejlersen Wæhrens
Prostaglandin receptor EP4 expression by Th17 cells is associated with high disease activity in ankylosing spondylitis
Charlotte Klasen, Anja Meyer, Paula S. Wittekind, Iris Waqué, Schafiq Nabhani, David M. Kofler
Comparison of an interactive voice response system and smartphone application in the identification of gout flares
Nada Elmagboul, Brian W. Coburn, Jeffrey Foster, Amy Mudano, Joshua Melnick, Debra Bergman, Shuo Yang, David Redden, Lang Chen, Cooper Filby, Jeffrey R. Curtis, Ted R. Mikuls, Kenneth G. Saag
Anti-D4GDI antibodies activate platelets in vitro: a possible link with thrombocytopenia in primary antiphospholipid syndrome
C. Barbati, L. Stefanini, T. Colasanti, E. Cipriano, A. Celia, G. Gabriele, M. Vomero, F. Ceccarelli, F. R. Spinelli, A. Finucci, M. Speziali, G. Orso, D. P. E. Margiotta, F. Conti, F. Violi, A. Afeltra, G. Valesini, C. Alessandri
Effect of disease-modifying anti-rheumatic drugs on bone structure and strength in psoriatic arthritis patients
David Simon, Arnd Kleyer, Sara Bayat, Koray Tascilar, Eleni Kampylafka, Timo Meinderink, Louis Schuster, Ramona Petrov, Anna-Maria Liphardt, Juergen Rech, Georg Schett, Axel J. Hueber
Effects of tapering tumor necrosis factor inhibitor on the achievement of inactive disease in patients with axial spondyloarthritis: a nationwide cohort study
Jun Won Park, Hyoun-Ah Kim, Kichul Shin, Yong-Beom Park, Tae-Hwan Kim, Yeong Wook Song, Eun Young Lee
The effect of deep or sustained remission on maintenance of remission after dose reduction or withdrawal of etanercept in patients with rheumatoid arthritis
Yoshiya Tanaka, Josef S. Smolen, Heather Jones, Annette Szumski, Lisa Marshall, Paul Emery
High baseline fat mass, but not lean tissue mass, is associated with high intensity low back pain and disability in community-based adults
Sharmayne R. E. Brady, Donna M. Urquhart, Sultana Monira Hussain, Andrew Teichtahl, Yuanyuan Wang, Anita E. Wluka, Flavia Cicuttini
Assessing synovitis in the hands in patients with rheumatoid arthritis by ultrasound: an agreement study exploring the most inflammatory active side from two Norwegian trials
Lene Terslev, Robin Christensen, Anna-Birgitte Aga, Joe Sexton, Espen A. Haavardsholm, Hilde B. Hammer
Chondrogenic induction of human osteoarthritic cartilage-derived mesenchymal stem cells activates mineralization and hypertrophic and osteogenic gene expression through a mechanomiR
Nan Hu, Yun Gao, Chathuraka T. Jayasuriya, Wenguang Liu, Heng Du, Jing Ding, Meng Feng, Qian Chen
Disease activity and damage in juvenile idiopathic arthritis: methotrexate era versus biologic era
Gabriella Giancane, Valentina Muratore, Valentina Marzetti, Neus Quilis, Belen Serrano Benavente, Francesca Bagnasco, Alessandra Alongi, Adele Civino, Lorenzo Quartulli, Alessandro Consolaro, Angelo Ravelli
Rheumatoid arthritis synovial fibroblasts promote TREM-1 expression in monocytes via COX-2/PGE2 pathway
Anping Peng, Xinyi Lu, Jun Huang, Min He, Jianhua Xu, Hui Huang, Qubo Chen
Correction to: Association between inflammation and systolic blood pressure in RA compared to patients without RA
Zhi Yu, Seoyoung C. Kim, Kathleen Vanni, Jie Huang, Rishi Desai, Shawn N. Murphy, Daniel H. Solomon, Katherine P. Liao
IL-1β receptor antagonist (IL-1Ra) combined with autophagy inducer (TAT-Beclin1) is an effective alternative for attenuating extracellular matrix degradation in rat and human osteoarthritis chondrocytes
Fen Wang, Jijie Liu, Xiaolei Chen, Xinpeng Zheng, Ning Qu, Bing Zhang, Chun Xia
Soluble syndecan-3 binds chemokines, reduces leukocyte migration in vitro and ameliorates disease severity in models of rheumatoid arthritis
Andrew D. Eustace, Emily F. McNaughton, Sophie King, Oksana Kehoe, Andreas Kungl, Derek Mattey, Angela H. Nobbs, Neil Williams, Jim Middleton
Meta-analysis of pain and function placebo responses in pharmacological osteoarthritis trials
ZeYu Huang, Jing Chen, Qin Sheng Hu, Qiang Huang, Jun Ma, Fu Xing Pei, Bin Shen, Virginia Byers Kraus
Distinct biomarkers for different bones in osteoporosis with rheumatoid arthritis
T. Tomizawa, H. Ito, K. Murata, M. Hashimoto, M. Tanaka, K. Murakami, K. Nishitani, M. Azukizawa, A. Okahata, K. Doi, M. Saito, M. Furu, M. Hamaguchi, T. Mimori, S. Matsuda
Differential effects of specific cathepsin S inhibition in biocompartments from patients with primary Sjögren syndrome
Patrick Hargreaves, Douglas Daoudlarian, Michel Theron, Fabrice A. Kolb, Marianne Manchester Young, Bernhard Reis, Andre Tiaden, Bettina Bannert, Diego Kyburz, Tobias Manigold
Urinary pro-thrombotic, anti-thrombotic, and fibrinolytic molecules as biomarkers of lupus nephritis
Ling Qin, Samantha Stanley, Huihua Ding, Ting Zhang, Van Thi Thanh Truong, Teja Celhar, Anna-Marie Fairhurst, Claudia Pedroza, Michelle Petri, Ramesh Saxena, Chandra Mohan
Smoking status and cause-specific discontinuation of tumour necrosis factor inhibitors in axial spondyloarthritis
Sizheng Steven Zhao, Kazuki Yoshida, Gareth T. Jones, David M. Hughes, Stephen J. Duffield, Sara K. Tedeschi, Houchen Lyu, Robert J. Moots, Daniel H. Solomon, Nicola J. Goodson
Disease interception with interleukin-17 inhibition in high-risk psoriasis patients with subclinical joint inflammation—data from the prospective IVEPSA study
Eleni Kampylafka, David Simon, Isabelle d’Oliveira, Christina Linz, Veronika Lerchen, Matthias Englbrecht, Juergen Rech, Arnd Kleyer, Michael Sticherling, Georg Schett, Axel J. Hueber
Bio-optimized Curcuma longa extract is efficient on knee osteoarthritis pain: a double-blind multicenter randomized placebo controlled three-arm study
Y. Henrotin, M. Malaise, R. Wittoek, K. de Vlam, J.-P. Brasseur, F. P. Luyten, Q. Jiangang, M. Van den Berghe, R. Uhoda, J. Bentin, T. De Vroey, L. Erpicum, A. F. Donneau, Y. Dierckxsens
Local ice cryotherapy decreases synovial interleukin 6, interleukin 1β, vascular endothelial growth factor, prostaglandin-E2, and nuclear factor kappa B p65 in human knee arthritis: a controlled study
X. Guillot, N. Tordi, C. Laheurte, L. Pazart, C. Prati, P. Saas, D. Wendling
Proteomic and histopathological characterisation of sicca subjects and primary Sjögren’s syndrome patients reveals promising tear, saliva and extracellular vesicle disease biomarkers
Lara A. Aqrawi, Hilde Kanli Galtung, Eduarda M. Guerreiro, Reidun Øvstebø, Bernd Thiede, Tor Paaske Utheim, Xiangjun Chen, Øygunn Aass Utheim, Øyvind Palm, Kathrine Skarstein, Janicke Liaaen Jensen
Therapeutic glucocorticoids prevent bone loss but drive muscle wasting when administered in chronic polyarthritis
C. G. Fenton, J. M. Webster, C. S. Martin, S. Fareed, C. Wehmeyer, H. Mackie, R. Jones, A. P. Seabright, J. W. Lewis, Y. C. Lai, C. S. Goodyear, S. W Jones, M. S. Cooper, G. G. Lavery, R. Langen, K. Raza, R. S. Hardy
Comparison of baricitinib, upadacitinib, and tofacitinib mediated regulation of cytokine signaling in human leukocyte subpopulations
Iain B. McInnes, Nicole L. Byers, Richard E. Higgs, Jonathan Lee, William L. Macias, Songqing Na, Robert A. Ortmann, Guilherme Rocha, Terence P. Rooney, Thomas Wehrman, Xin Zhang, Steven H. Zuckerman, Peter C. Taylor
Tofacitinib facilitates the expansion of myeloid-derived suppressor cells and ameliorates interstitial lung disease in SKG mice
Sho Sendo, Jun Saegusa, Hirotaka Yamada, Keisuke Nishimura, Akio Morinobu
Correction to: Urinary pro-thrombotic, anti-thrombotic, and fibrinolytic molecules as biomarkers of lupus nephritis
Ling Qin, Samantha Stanley, Huihua Ding, Ting Zhang, Van Thi Thanh Truong, Teja Celhar, Anna-Marie Fairhurst, Claudia Pedroza, Michelle Petri, Ramesh Saxena, Chandra Mohan
Up-regulation of circulating microRNA-17 is associated with lumbar radicular pain following disc herniation
Eivind Hasvik, Tiril Schjølberg, Daniel Pitz Jacobsen, Anne Julsrud Haugen, Lars Grøvle, Elina Iordanova Schistad, Johannes Gjerstad
Alcohol consumption as a predictor of the progression of spinal structural damage in axial spondyloarthritis: data from the Catholic Axial Spondyloarthritis COhort (CASCO)
Hong Ki Min, Jennifer Lee, Ji Hyeon Ju, Sung-Hwan Park, Seung-Ki Kwok
11β-HSD1 plays a critical role in trabecular bone loss associated with systemic glucocorticoid therapy
C. G. Fenton, C. L. Doig, S. Fareed, A. Naylor, A. P. Morrell, O. Addison, C. Wehmeyer, C. D. Buckley, M. S. Cooper, G. G. Lavery, K. Raza, R. S. Hardy
Clinical features of central nervous system infections and experience in differential diagnosis from neuropsychiatric lupus erythematosus in a cohort of 8491 patients with systemic lupus erythematosus
Mengdi Jiang, Xiaochun Shi, Xin Gao, Jingwen Niu, Xiaomin Hu, Lidan Zhao, Xuan Zhang
Efficacy and safety of intravenous golimumab plus methotrexate in patients with rheumatoid arthritis aged < 65 years and those ≥ 65 years of age
John Tesser, Shelly Kafka, Raphael J. DeHoratius, Stephen Xu, Elizabeth C. Hsia, Anthony Turkiewicz
Abrogation of lysophosphatidic acid receptor 1 ameliorates murine vasculitis
Chie Miyabe, Yoshishige Miyabe, Jun Nagai, Noriko N. Miura, Naohito Ohno, Jerold Chun, Ryoji Tsuboi, Hiroshi Ueda, Masayuki Miyasaka, Nobuyuki Miyasaka, Toshihiro Nanki
Prognostic factors for progression of osteoarthritis of the hip: a systematic review
C. H. Teirlinck, D. M. J. Dorleijn, P. K. Bos, J. B. M. Rijkels-Otters, S. M. A. Bierma-Zeinstra, P. A. J. Luijsterburg
Curcumin attenuates MSU crystal-induced inflammation by inhibiting the degradation of IκBα and blocking mitochondrial damage
Baofeng Chen, Hongmei Li, Guochun Ou, Long Ren, Xiaohong Yang, Mei Zeng
Integrating transcriptome-wide study and mRNA expression profiles yields novel insights into the biological mechanism of chondropathies
Ping Li, Yujie Ning, Xiong Guo, Yan Wen, Bolun Cheng, Mei Ma, Lu Zhang, Shiqiang Cheng, Sen Wang, Feng Zhang
Deletion at 2q14.3 is associated with worse response to TNF-α blockers in patients with rheumatoid arthritis
Ki-Nam Gu, So-Young Bang, Hye-Soon Lee, Youngho Park, Ju-Yeon Kang, Ji-Soong Kim, Bora Nam, Hyun-Seung Yoo, Jung-Min Shin, Yeon-Kyung Lee, Tae-Han Lee, Sehwan Chun, Soo-Kyung Cho, Chan-Bum Choi, Yoon-Kyoung Sung, Tae-Hwan Kim, Jae-Bum Jun, Dae Hyun Yoo, Kwangwoo Kim, Sang-Cheol Bae
Risk of immune-mediated inflammatory diseases in newly diagnosed ankylosing spondylitis patients: a population-based matched cohort study
Hsin-Hua Chen, Wen-Cheng Chao, Yi-Hsing Chen, Tsu-Yi Hsieh, Kuo-Lung Lai, Yi-Ming Chen, Wei-Ting Hung, Ching-Tsai Lin, Chih-Wei Tseng, Ching-Heng Lin
A patient-reported questionnaire developed in a German early arthritis cohort to assess periodontitis in patients with rheumatoid arthritis
Johanna Callhoff, Thomas Dietrich, Mariya Chubrieva, Jens Klotsche, Angela Zink
CCR6+ group 3 innate lymphoid cells accumulate in inflamed joints in rheumatoid arthritis and produce Th17 cytokines
Ayako Takaki-Kuwahara, Yojiro Arinobu, Kohta Miyawaki, Hisakata Yamada, Hirofumi Tsuzuki, Kensuke Irino, Masahiro Ayano, Yasutaka Kimoto, Hiroki Mitoma, Mitsuteru Akahoshi, Hiroshi Tsukamoto, Takahiko Horiuchi, Hiroaki Niiro, Koichi Akashi
Respiratory viral infections and the risk of rheumatoid arthritis
Young Bin Joo, Youn-Hee Lim, Ki-Jo Kim, Kyung-Su Park, Yune-Jung Park
Baseline urate level and renal function predict outcomes of urate-lowering therapy using low doses of febuxostat and benzbromarone: a prospective, randomized controlled study in a Chinese primary gout cohort
Nan Liang, Mingshu Sun, Ruixia Sun, Ting Xu, Lingling Cui, Can Wang, Lidan Ma, Xiaoyu Cheng, Xiaomei Xue, Wenyan Sun, Xuan Yuan, Hui Zhang, Hailong Li, Yuwei He, Aichang Ji, Xinjiang Wu, Changgui Li
Long non-coding RNA HOTAIR modulates intervertebral disc degenerative changes via Wnt/β-catenin pathway
Shengfeng Zhan, Kun Wang, Yu Song, Shuai Li, Huipeng Yin, Rongjin Luo, Zhiwei Liao, Xinghuo Wu, Yukun Zhang, Cao Yang
A multicenter randomized, double-blind, placebo-controlled pilot study to assess the efficacy and safety of riociguat in systemic sclerosis-associated digital ulcers
Vivek Nagaraja, Cathie Spino, Erica Bush, Pei-Suen Tsou, Robyn T. Domsic, Robert Lafyatis, Tracy Frech, Jessica K. Gordon, Virginia D. Steen, Dinesh Khanna
Associations between biomarkers of bone and cartilage turnover, gender, pain categories and radiographic severity in knee osteoarthritis
Asger Reinstrup Bihlet, Inger Byrjalsen, Anne-Christine Bay-Jensen, Jeppe Ragnar Andersen, Claus Christiansen, Bente Juel Riis, Morten A. Karsdal
Subclinical and clinical atherosclerosis in rheumatoid arthritis: results from the 3-year, multicentre, prospective, observational GIRRCS (Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale) study
Piero Ruscitti, Paola Cipriani, Vasiliki Liakouli, Daniela Iacono, Ilenia Pantano, Domenico Paolo Emanuele Margiotta, Luca Navarini, Giulia Maria Destro Castaniti, Nicola Maruotti, Gerardo Di Scala, Licia Picciariello, Francesco Caso, Sara Bongiovanni, Rosa Daniela Grembiale, Fabiola Atzeni, Raffaele Scarpa, Federico Perosa, Giacomo Emmi, Francesco Paolo Cantatore, Giuliana Guggino, Antonella Afeltra, Francesco Ciccia, Roberto Giacomelli
Interferon-α exacerbates neuropsychiatric phenotypes in lupus-prone mice
Jing Zeng, Xinyu Meng, Ping Zhou, Zhihua Yin, Qinglian Xie, Hong Zou, Nan Shen, Zhizhong Ye, Yuanjia Tang
Cartilage endoplasmic reticulum stress may influence the onset but not the progression of experimental osteoarthritis
Louise H. W. Kung, Lorna Mullan, Jamie Soul, Ping Wang, Kazutoshi Mori, John F. Bateman, Michael D. Briggs, Raymond P. Boot-Handford
Pneumocystis pneumonia in patients with rheumatic diseases receiving prolonged, non-high-dose steroids—clinical implication of primary prophylaxis using trimethoprim–sulfamethoxazole
Jun Won Park, Jeffrey R. Curtis, Min Jung Kim, Hajeong Lee, Yeong Wook Song, Eun Bong Lee
Sustained remission with methotrexate monotherapy after 22-week induction treatment with TNF-alpha inhibitor and methotrexate in early psoriatic arthritis: an open-label extension of a randomized placebo-controlled trial
Henriëtte M. Y. de Jong, Leonieke J. J. van Mens, Michael T. Nurmohamed, Marc R. Kok, Arno W. R. van Kuijk, Dominique L. P. Baeten, Marleen G. H. van de Sande
Fluorescence optical imaging for treatment monitoring in patients with early and active rheumatoid arthritis in a 1-year follow-up period
Anne-Marie Glimm, Lisa Ines Sprenger, Ida Kristin Haugen, Ulrich Mansmann, Sandra Hermann, Thomas Häupl, Paula Hoff, Gerd-Rüdiger Burmester, Marina Backhaus, Lien Le, Sarah Ohrndorf
Impact of urate-lowering drugs on the progression and recovery from chronic kidney disease among gout patients
Ting-Ting Chung, Kuang-Hui Yu, Chang-Fu Kuo, Shue-Fen Luo, Meng-Jiun Chiou, Wen-Ching Lan, Jung-Sheng Chen, Wen-Yi Tseng, Ao-Ho Hsieh, Lian-Chin Wang
Comparing the burdens of opportunistic infections among patients with systemic rheumatic diseases: a nationally representative cohort study
Chung-Yuan Hsu, Chi-Hua Ko, Jiun-Ling Wang, Tsai-Ching Hsu, Chun-Yu Lin
Invariant natural killer T cells are functionally impaired in patients with systemic sclerosis
Ann-Christin Pecher, Felix Kettemann, Elisa Asteriti, Hannes Schmid, Silke Duerr-Stoerzer, Hildegard Keppeler, Joerg Christoph Henes, Reinhild Klein, Clemens Hinterleitner, Kathy-Ann Secker, Corina Schneidawind, Lothar Kanz, Dominik Schneidawind
JAG2/Notch2 inhibits intervertebral disc degeneration by modulating cell proliferation, apoptosis, and extracellular matrix
Jun Long, Xiaobo Wang, Xianfa Du, Hehai Pan, Jianru Wang, Zemin Li, Hui Liu, Xudong Li, Zhaomin Zheng
Very early MRI responses to therapy as a predictor of later radiographic progression in early rheumatoid arthritis
Philip G. Conaghan, Mikkel Østergaard, Orrin Troum, Michael A. Bowes, Gwenael Guillard, Bethanie Wilkinson, Zhiyong Xie, John Andrews, Amy Stein, Douglass Chapman, Andrew Koenig
Depression in ankylosing spondylitis and the role of disease-related and contextual factors: a cross-sectional study
Casper Webers, Laura Vanhoof, Carsten Leue, Annelies Boonen, Sebastian Köhler
Molecular profiling of rheumatoid arthritis patients reveals an association between innate and adaptive cell populations and response to anti-tumor necrosis factor
Victor Farutin, Thomas Prod’homme, Kevin McConnell, Nathaniel Washburn, Patrick Halvey, Carol J. Etzel, Jamey Guess, Jay Duffner, Kristen Getchell, Robin Meccariello, Bryan Gutierrez, Christopher Honan, Ganlin Zhao, Nicholas A. Cilfone, Nur Sibel Gunay, Jan L. Hillson, David S. DeLuca, Katherine C. Saunders, Dimitrios A. Pappas, Jeffrey D. Greenberg, Joel M. Kremer, Anthony M. Manning, Leona E. Ling, Ishan Capila
Early treatment with ambrisentan of mildly elevated mean pulmonary arterial pressure associated with systemic sclerosis: a randomized, controlled, double-blind, parallel group study (EDITA study)
Zixuan Pan, Alberto M. Marra, Nicola Benjamin, Christina A. Eichstaedt, Norbert Blank, Eduardo Bossone, Antonio Cittadini, Gerry Coghlan, Christopher P. Denton, Oliver Distler, Benjamin Egenlauf, Christine Fischer, Satenik Harutyunova, Panagiota Xanthouli, Hanns-Martin Lorenz, Ekkehard Grünig
Outcome in juvenile idiopathic arthritis: a population-based study from Sweden
Elisabet Berthold, Bengt Månsson, Robin Kahn
Familial early-onset hyperuricemia and gout associated with a newly identified dysfunctional variant in urate transporter ABCG2
Yu Toyoda, Kateřina Pavelcová, Martin Klein, Hiroshi Suzuki, Tappei Takada, Blanka Stiburkova
Potential therapeutic effects of cyanidin-3-O-glucoside on rheumatoid arthritis by relieving inhibition of CD38+ NK cells on Treg cell differentiation
Hongxing Wang, Shutong Li, Guoqing Zhang, Hui Wu, Xiaotian Chang
The impact of sex and disease classification on patient-reported outcome measures in axial spondyloarthritis: a descriptive prospective cross-sectional study
Rikke A. Andreasen, Lars E. Kristensen, Kenneth Egstrup, Xenofon Baraliakos, Vibeke Strand, Hans Christian Horn, Inger M. J. Hansen, Robin Christensen, Torkell Ellingsen
Factors related to the use of opioids as early treatment in patients with knee osteoarthritis
Soo-Kyung Cho, Sun-Young Jung, Seongmi Choi, Seul Gi Im, Hyoungyoung Kim, Woo Seok Choi, Eun Jin Jang, Yoon-Kyoung Sung
Fatigue severity in anti-nuclear antibody-positive individuals does not correlate with pro-inflammatory cytokine levels or predict imminent progression to symptomatic disease
Waleed Hafiz, Rawad Nori, Ariana Bregasi, Babak Noamani, Dennisse Bonilla, Larissa Lisnevskaia, Earl Silverman, Arthur A. M. Bookman, Sindhu R. Johnson, Carolina Landolt-Marticorena, Joan Wither
Serum lysophosphatidylcholines to phosphatidylcholines ratio is associated with symptomatic responders to symptomatic drugs in knee osteoarthritis patients
Guangju Zhai, Jean-Pierre Pelletier, Ming Liu, Edward W. Randell, Proton Rahman, Johanne Martel-Pelletier
Inhibition of spinal bone formation in AS: 10 years after comparing adalimumab to OASIS
Désirée van der Heijde, Robert Landewé
How thorough clinical observational studies on rheumatoid arthritis can have an impact on the field
A. H. M. van der Helm-van Mil
Comparative risk of malignancies and infections in patients with rheumatoid arthritis initiating abatacept versus other biologics: a multi-database real-world study
Teresa A. Simon, Maarten Boers, Marc Hochberg, Nicole Baker, Mary L. Skovron, Nitesh Ray, Sanket Singhal, Samy Suissa, Andres Gomez-Caminero
Acute kidney injury associated with febuxostat and allopurinol: a post-marketing study
Amayelle Rey, Benjamin Batteux, Solène M. Laville, Justine Marienne, Kamel Masmoudi, Valérie Gras-Champel, Sophie Liabeuf
The feasibility of developing biomarkers from peripheral blood mononuclear cell RNAseq data in children with juvenile idiopathic arthritis using machine learning approaches
Kerry E. Poppenberg, Kaiyu Jiang, Lu Li, Yijun Sun, Hui Meng, Carol A. Wallace, Teresa Hennon, James N. Jarvis
Disease activity improvements with optimal discriminatory ability between treatment arms: applicability in early and established rheumatoid arthritis clinical trials
Josef Smolen, Roy Fleischmann, Daniel Aletaha, Yihan Li, Yijie Zhou, Iain Sainsbury, Ivan Lagunes Galindo
High-quality cooperative research: studies that represent a triumph in the rheumatology community
Teresa A. Simon
Population-specific factors associated with fractional excretion of uric acid
Ravi K. Narang, Zoe Vincent, Amanda Phipps-Green, Lisa K. Stamp, Tony R. Merriman, Nicola Dalbeth
Effective treatment of TNFα inhibitors in Chinese patients with Blau syndrome
Jing Chen, Yi Luo, Mengzhu Zhao, Di Wu, Yunjiao Yang, Wen Zhang, Min Shen
Radiographic progression can still occur in individual patients with low or moderate disease activity in the current treat-to-target paradigm: real-world data from the Dutch Rheumatoid Arthritis Monitoring (DREAM) registry
Peter M. ten Klooster, Letty G. A. Versteeg, Martijn A. H. Oude Voshaar, Inmaculada de la Torre, Francesco De Leonardis, Walid Fakhouri, Liliana Zaremba-Pechmann, Mart van de Laar
Interleukin-1 receptor antagonist (IL-1Ra) is more effective in suppressing cytokine-induced catabolism in cartilage-synovium co-culture than in cartilage monoculture
Shikhar Mehta, Sumayyah Akhtar, Ryan M. Porter, Patrik Önnerfjord, Ambika G. Bajpayee
Bone marrow mesenchymal stem cells in rheumatoid arthritis, spondyloarthritis, and ankylosing spondylitis: problems rather than solutions?
Jean-Marie Berthelot, Benoit Le Goff, Yves Maugars
iNOS dependent and independent phases of lymph node expansion in mice with TNF-induced inflammatory-erosive arthritis
Richard D. Bell, Pamelia N. Slattery, Emily K. Wu, Lianping Xing, Christopher T. Ritchlin, Edward M. Schwarz
European Network of Pregnancy Registers in Rheumatology (EuNeP)—an overview of procedures and data collection
Yvette Meissner, Anja Strangfeld, Nathalie Costedoat-Chalumeau, Frauke Förger, Doreen Goll, Anna Molto, Rebecca Özdemir, Marianne Wallenius, Rebecca Fischer-Betz
Cardiovascular disease in the QUEST-RA study, 10 years later
Antonio Naranjo, Iván Ferraz-Amaro
Predictors of good response to conventional synthetic DMARDs in early seronegative rheumatoid arthritis: data from the ESPOIR cohort
Cédric Lukas, Julia Mary, Michel Debandt, Claire Daïen, Jacques Morel, Alain Cantagrel, Bruno Fautrel, Bernard Combe
Introducing our 20th anniversary collection
Christopher D Buckley, Harris Perlman
B lymphocyte stimulator modulates number and function of endothelial progenitor cells in systemic lupus erythematosus
Francesca Romana Spinelli, Cristiana Barbati, Fulvia Cecarelli, Francesca Morello, Tania Colasanti, Marta Vomero, Laura Massaro, Valeria Orefice, Cristiano Alessandri, Guido Valesini, Fabrizio Conti
Asthma and elevation of anti-citrullinated protein antibodies prior to the onset of rheumatoid arthritis
Alessandra Zaccardelli, Xinyi Liu, Julia A. Ford, Jing Cui, Bing Lu, Su H. Chu, Peter H. Schur, Cameron B. Speyer, Karen H. Costenbader, William H. Robinson, Jeremy Sokolove, Elizabeth W. Karlson, Carlos A. Camargo Jr, Jeffrey A. Sparks
Wnt/β-catenin signaling contributes to articular cartilage homeostasis through lubricin induction in the superficial zone
Fengjun Xuan, Fumiko Yano, Daisuke Mori, Ryota Chijimatsu, Yuji Maenohara, Hideki Nakamoto, Yoshifumi Mori, Yuma Makii, Takeshi Oichi, Makoto Mark Taketo, Hironori Hojo, Shinsuke Ohba, Ung-il Chung, Sakae Tanaka, Taku Saito
A distinct gut microbiota composition in patients with ankylosing spondylitis is associated with increased levels of fecal calprotectin
Eva Klingberg, Maria K. Magnusson, Hans Strid, Anna Deminger, Arne Ståhl, Johanna Sundin, Magnus Simrén, Hans Carlsten, Lena Öhman, Helena Forsblad-d’Elia
A search to the target tissue in which RA-specific inflammation starts: a detailed MRI study to improve identification of RA-specific features in the phase of clinically suspect arthralgia
Xanthe M. E. Matthijssen, Fenne Wouters, Debbie M. Boeters, Aleid C. Boer, Yousra J. Dakkak, Ellis Niemantsverdriet, Annette H. M. van der Helm-van Mil
Hydroxychloroquine inhibits IL-1β production from amyloid-stimulated human neutrophils
Yuya Fujita, Naoki Matsuoka, Jumpei Temmoku, Makiko Yashiro Furuya, Tomoyuki Asano, Shuzo Sato, Hiroko Kobayashi, Hiroshi Watanabe, Eiji Suzuki, Takeshi Urano, Hideko Kozuru, Hiroshi Yatsuhashi, Tomohiro Koga, Atsushi Kawakami, Kiyoshi Migita
The effect of pilocarpine on dental caries in patients with primary Sjögren’s syndrome: a database prospective cohort study
Chung-Yuan Hsu, Kuo-Chun Hung, Ming-Shyan Lin, Chi-Hua Ko, Yu-Sheng Lin, Tien-Hsing Chen, Chun-Yu Lin, Ying-Chou Chen
Contribution of adipocyte precursors in the phenotypic specificity of intra-articular adipose tissues in knee osteoarthritis patients
Florent Eymard, Audrey Pigenet, Cindy Rose, Anouchka Bories, Charles-Henri Flouzat-Lachaniette, Francis Berenbaum, Xavier Chevalier, Xavier Houard, Geoffroy Nourissat
Arterial stiffness correlates with progressive nailfold capillary microscopic changes in systemic sclerosis: results from a cross-sectional study
Stergios Soulaidopoulos, Eleni Pagkopoulou, Niki Katsiki, Eva Triantafyllidou, Asterios Karagiannis, Alexandros Garyfallos, George D. Kitas, Theodoros Dimitroulas
Safety and efficacy of a new micronized formulation of the ALIAmide palmitoylglucosamine in preclinical models of inflammation and osteoarthritis pain
Marika Cordaro, Rosalba Siracusa, Daniela Impellizzeri, Ramona D’ Amico, Alessio Filippo Peritore, Rosalia Crupi, Enrico Gugliandolo, Roberta Fusco, Rosanna Di Paola, Carlo Schievano, Salvatore Cuzzocrea
Risk stratification and clinical course of hepatitis B virus reactivation in rheumatoid arthritis patients with resolved infection: final report of a multicenter prospective observational study at Japanese Red Cross Hospital
Wataru Fukuda, Tadamasa Hanyu, Masaki Katayama, Shinichi Mizuki, Akitomo Okada, Masayuki Miyata, Yuichi Handa, Masatoshi Hayashi, Yoshinobu Koyama, Kaoru Arii, Toshiyuki Kitaori, Hiroyuki Hagiyama, Yoshinori Urushidani, Takahito Yamasaki, Yoshihiko Ikeno, Takeshi Suzuki, Atsushi Omoto, Toshifumi Sugitani, Satoshi Morita, Shigeko Inokuma
Associations between certolizumab pegol serum levels, anti-drug antibodies and treatment response in patients with inflammatory joint diseases: data from the NOR-DMARD study
Johanna Elin Gehin, Guro Løvik Goll, David John Warren, Silje Watterdal Syversen, Joseph Sexton, Eldri Kveine Strand, Tore Kristian Kvien, Nils Bolstad, Elisabeth Lie
Association between pain phenotype and disease activity in rheumatoid arthritis patients: a non-interventional, longitudinal cohort study
P. M. ten Klooster, N. de Graaf, H. E. Vonkeman
NEMO score in nailfold videocapillaroscopy is a good tool to assess both steady state levels and overtime changes of disease activity in patients with systemic sclerosis: a comparison with the proposed composite indices for this disease status entity
Francesca Pignataro, Wanda Maglione, Antonina Minniti, Domenico Sambataro, Gianluca Sambataro, Francesco Campanaro, Gabriele Valentini, Claudio Vitali, Nicoletta Del Papa
Increased levels of anti-dsDNA antibodies in immune complexes before treatment with belimumab associate with clinical response in patients with systemic lupus erythematosus
Azita Sohrabian, Ioannis Parodis, Nellie Carlströmer-Berthén, Martina Frodlund, Andreas Jönsen, Agneta Zickert, Christopher Sjöwall, Anders A. Bengtsson, Iva Gunnarsson, Johan Rönnelid
Interferon score is increased in incomplete systemic lupus erythematosus and correlates with myxovirus-resistance protein A in blood and skin
Wietske M. Lambers, Karina de Leeuw, Berber Doornbos-van der Meer, Gilles F.H. Diercks, Hendrika Bootsma, Johanna Westra
ALW peptide ameliorates lupus nephritis in MRL/lpr mice
Huixia Wang, Mei Lu, Siyue Zhai, Kunyi Wu, Lingling Peng, Jie Yang, Yumin Xia
Inflammatory stays inflammatory: a subgroup of systemic sclerosis characterized by high morbidity and inflammatory resistance to cyclophosphamide
Aleksey Mitev, Lisa Christ, Daria Feldmann, Moritz Binder, Kim Möller, Anna-Maria Kanne, Thomas Hügle, Peter M. Villiger, Reinhard E. Voll, Stephanie Finzel, Florian Kollert
Effects of upadacitinib on patient-reported outcomes: results from SELECT-BEYOND, a phase 3 randomized trial in patients with rheumatoid arthritis and inadequate responses to biologic disease-modifying antirheumatic drugs
Vibeke Strand, Michael Schiff, Namita Tundia, Alan Friedman, Sebastian Meerwein, Aileen Pangan, Arijit Ganguli, Mahesh Fuldeore, Yan Song, Janet Pope
Arthritis sensory and motor scale: predicting functional deficits from the clinical score in collagen-induced arthritis
Anne-Laure Mausset-Bonnefont, Maïlys Cren, Rita Vicente, Julie Quentin, Christian Jorgensen, Florence Apparailly, Pascale Louis-Plence
Progressive structural bone changes and their relationship with treatment in patients with psoriatic arthritis: a longitudinal HR-pQCT study
Dongze Wu, James F. Griffith, Steven H. M. Lam, Priscilla C. H. Wong, Lin Shi, Edmund K. Li, Isaac T. Cheng, Tena K. Li, Vivian W. Hung, Ling Qin, Lai-Shan Tam
Secukinumab efficacy on resolution of enthesitis in psoriatic arthritis: pooled analysis of two phase 3 studies
Laura C. Coates, Johan K. Wallman, Dennis McGonagle, Georg A. Schett, Iain B. McInnes, Philip J. Mease, Lawrence Rasouliyan, Erhard Quebe-Fehling, Darren L. Asquith, Andreas E. R. Fasth, Luminita Pricop, Corine Gaillez
Diagnostic performance of serum cystatin C and complement component 1q in lupus nephritis
Bei Xu, Ya-mei Zhang, Yu-wei Yang, Yun-shuang Liu, Jia-fu Feng
Circulating calprotectin (S100A8/A9) is higher in rheumatoid arthritis patients that relapse within 12 months of tapering anti-rheumatic drugs
Emma C. de Moel, Jürgen Rech, Michael Mahler, Johannes Roth, Thomas Vogl, Anne Schouffoer, Robbert J. Goekoop, Tom W. J. Huizinga, Cornelia F. Allaart, René E. M. Toes, Georg Schett, Diane van der Woude
Safety, tolerability, pharmacokinetics, and pharmacodynamics of PF-06650833, a selective interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor, in single and multiple ascending dose randomized phase 1 studies in healthy subjects
Spencer I. Danto, Negin Shojaee, Ravi Shankar P. Singh, Cheryl Li, Steven A. Gilbert, Zorayr Manukyan, Iain Kilty
Validation of prediction models of severe disease course and non-achievement of remission in juvenile idiopathic arthritis: part 1—results of the Canadian model in the Nordic cohort
Veronika Rypdal, Jaime Guzman, Andrew Henrey, Thomas Loughin, Mia Glerup, Ellen Dalen Arnstad, Kristiina Aalto, Marite Rygg, Susan Nielsen, Troels Herlin, Anders Fasth, Lillemor Berntson, Martin Rypdal, Ellen Nordal
Long non-coding XIST raises methylation of TIMP-3 promoter to regulate collagen degradation in osteoarthritic chondrocytes after tibial plateau fracture
Hongwei Chen, Shengdi Yang, Ruyi Shao
Upadacitinib improves patient-reported outcomes in patients with rheumatoid arthritis and inadequate response to conventional synthetic disease-modifying antirheumatic drugs: results from SELECT-NEXT
Vibeke Strand, Janet Pope, Namita Tundia, Alan Friedman, Heidi S. Camp, Aileen Pangan, Arijit Ganguli, Mahesh Fuldeore, Debbie Goldschmidt, Michael Schiff
Association of age, sex and BMI with the rate of change in tibial cartilage volume: a 10.7-year longitudinal cohort study
Guoqi Cai, Matthew Jiang, Flavia Cicuttini, Graeme Jones
Complex assessment of bone mineral density, fracture risk, vitamin D status, and bone metabolism in Hungarian systemic sclerosis patients
Ágnes Horváth, Edit Végh, Anita Pusztai, Zsófia Pethő, Attila Hamar, Monika Czókolyová, Harjit Pal Bhattoa, Gábor Nagy, Balázs Juhász, Katalin Hodosi, Andrea Domján, Zoltán Szekanecz, Gabriella Szücs, Szilvia Szamosi
Management of adult-onset Still’s disease with interleukin-1 inhibitors: evidence- and consensus-based statements by a panel of Italian experts
Serena Colafrancesco, Maria Manara, Alessandra Bortoluzzi, Teodora Serban, Gerolamo Bianchi, Luca Cantarini, Francesco Ciccia, Lorenzo Dagna, Marcello Govoni, Carlomaurizio Montecucco, Roberta Priori, Angelo Ravelli, Paolo Sfriso, Luigi Sinigaglia
LNA-anti-miR-150 ameliorated kidney injury of lupus nephritis by inhibiting renal fibrosis and macrophage infiltration
Junjun Luan, Jingqi Fu, Chengjie Chen, Congcong Jiao, Weiwei Kong, Yixiao Zhang, Qing Chang, Yanqiu Wang, Detian Li, Gabor G. Illei, Jeffrey B. Kopp, Jingbo Pi, Hua Zhou
Activation of natural killer cells by rituximab in granulomatosis with polyangiitis
Doris Urlaub, Shuyang Zhao, Norbert Blank, Raoul Bergner, Maren Claus, Theresa Tretter, Hanns-Martin Lorenz, Carsten Watzl, Wolfgang Merkt
Proposition of a novel animal model of systemic sclerosis induced by type V collagen in C57BL/6 mice that reproduces fibrosis, vasculopathy and autoimmunity
Walcy Rosolia Teodoro, Zelita Aparecida de Jesus Queiroz, Lais Araujo dos Santos, Sergio Catanozi, Antonio dos Santos Filho, Cleonice Bueno, Margarete B. G. Vendramini, Sandra de Morais Fernezlian, Esmeralda M. Eher, Percival D. Sampaio-Barros, Sandra Gofinet Pasoto, Fernanda Degobbi T. Q. S. Lopes, Ana Paula Pereira Velosa, Vera Luiza Capelozzi
The value of MRI examination on bilateral hands including proximal interphalangeal joints for disease assessment in patients with early rheumatoid arthritis: a cross-sectional cohort study
Ying-Qian Mo, Ze-Hong Yang, Jun-Wei Wang, Qian-Hua Li, Xin-Yun Du, T. W. Huizinga, X. M. E. Matthijssen, Guang-Zi Shi, Jun Shen, Lie Dai
Improved RA classification among early arthritis patients with the concordant presence of three RA autoantibodies: analysis in two early arthritis clinics
Cristina Regueiro, Lorena Rodríguez-Martínez, Laura Nuño, Ana M. Ortiz, Alejandro Villalba, Dora Pascual-Salcedo, Ana Martínez-Feito, Isidoro González-Alvaro, Alejandro Balsa, Antonio Gonzalez
Is 18F-FDG PET/CT useful for diagnosing relapsing polychondritis with airway involvement and monitoring response to steroid-based therapy?
Yunxiang Zeng, Minfang Li, Sheng Chen, Lin Lin, Shiyue Li, Jianxing He, Jinlin Wang
Promotion of osteoclastogenesis by IL-26 in rheumatoid arthritis
Kyung-Ann Lee, Kyoung-Woon Kim, Bo-Mi Kim, Ji-Yeon Won, Hong Ki Min, Dhong Won Lee, Hae-Rim Kim, Sang-Heon Lee
Alterations of voluntary behavior in the course of disease progress and pharmacotherapy in mice with collagen-induced arthritis
Yohsuke Oto, Yukari Takahashi, Daitaro Kurosaka, Fusao Kato
Will savings from biosimilars offset increased costs related to dose escalation? A comparison of infliximab and golimumab for rheumatoid arthritis
Jeffrey R. Curtis, Fenglong Xie, Jonathan Kay, Joel D Kallich
Hyaluronic acid and platelet-rich plasma, a new therapeutic alternative for scleroderma patients: a prospective open-label study
Roberto Pirrello, Barbara Verro, Giulia Grasso, Piero Ruscitti, Adriana Cordova, Roberto Giacomelli, Francesco Ciccia, Giuliana Guggino
Performance of cytokine models in predicting SLE activity
Nopparat Ruchakorn, Pintip Ngamjanyaporn, Thanitta Suangtamai, Thanuchporn Kafaksom, Charin Polpanumas, Veerachat Petpisit, Trairak Pisitkun, Prapaporn Pisitkun
Protein profiling and network enrichment analysis in individuals before and after the onset of rheumatoid arthritis
Mikael Brink, Anders Lundquist, Andrey Alexeyenko, Kristina Lejon, Solbritt Rantapää-Dahlqvist
The burden of metabolic syndrome on osteoarthritic joints
Bruce M. Dickson, Anke J. Roelofs, Justin J. Rochford, Heather M. Wilson, Cosimo De Bari
DZ2002 ameliorates fibrosis, inflammation, and vasculopathy in experimental systemic sclerosis models
Zongwang Zhang, Yanwei Wu, Bing Wu, Qing Qi, Heng Li, Huimin Lu, Chen Fan, Chunlan Feng, Jianping Zuo, Lili Niu, Wei Tang
Pharmacological inhibition of TAK1, with the selective inhibitor takinib, alleviates clinical manifestation of arthritis in CIA mice
Scott A. Scarneo, Liesl S. Eibschutz, Phillip J. Bendele, Kelly W. Yang, Juliane Totzke, Philip Hughes, David A. Fox, Timothy A. J. Haystead
The immune system in sporadic inclusion body myositis patients is not compromised by blood-flow restricted exercise training
Kasper Yde Jensen, Mikkel Jacobsen, Henrik Daa Schrøder, Per Aagaard, Jakob Lindberg Nielsen, Anders Nørkær Jørgensen, Eleanor Boyle, Rune Dueholm Bech, Sofie Rosmark, Louise Pyndt Diederichsen, Ulrik Frandsen
Integrated systems analysis of salivary gland transcriptomics reveals key molecular networks in Sjögren’s syndrome
Hong Ki Min, Su-Jin Moon, Kyung-Su Park, Ki-Jo Kim
High-throughput sequencing of CD4+ T cell repertoire reveals disease-specific signatures in IgG4-related disease
Liwen Wang, Panpan Zhang, Jieqiong Li, Hui Lu, Linyi Peng, Jing Ling, Xuan Zhang, Xiaofeng Zeng, Yan Zhao, Wen Zhang
Native myeloperoxidase is required to make the experimental vasculitis model
Mayu Nonokawa, Ku Suzuki, Hideyuki Hayashi, Yuka Nishibata, Sakiko Masuda, Daigo Nakazawa, Satoshi Tanaka, Utano Tomaru, Akihiro Ishizu
Enhanced angiogenic function in response to fibroblasts from psoriatic arthritis synovium compared to rheumatoid arthritis
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