Ausgabe 1/2018
Inhalt (286 Artikel)
Abatacept used in combination with non-methotrexate disease-modifying antirheumatic drugs: a descriptive analysis of data from interventional trials and the real-world setting
Rieke Alten, Harald Burkhardt, Eugen Feist, Klaus Krüger, Juergen Rech, Andrea Rubbert-Roth, Reinhard E. Voll, Yedid Elbez, Christiane Rauch
One-year risk of serious infection in patients treated with certolizumab pegol as compared with other TNF inhibitors in a real-world setting: data from a national U.S. rheumatoid arthritis registry
Leslie R. Harrold, Heather J. Litman, Katherine C. Saunders, Kimberly J. Dandreo, Bernice Gershenson, Jeffrey D. Greenberg, Robert Low, Jeffrey Stark, Robert Suruki, Srihari Jaganathan, Joel M. Kremer, Mohamed Yassine
The epidemiology of psoriatic arthritis in Israel – a population-based study
Lihi Eder, Arnon Dov Cohen, Ilan Feldhamer, Sari Greenberg-Dotan, Erez Batat, Devy Zisman
Type I IFN signature in childhood-onset systemic lupus erythematosus: a conspiracy of DNA- and RNA-sensing receptors?
M. Javad Wahadat, Iris L. A. Bodewes, Naomi I. Maria, Cornelia G. van Helden-Meeuwsen, Annette van Dijk-Hummelman, Eline C. Steenwijk, Sylvia Kamphuis, Marjan A. Versnel
Are we there yet? An update on transitional care in rheumatology
Janet E. McDonagh, Albert Farre
Urinary angiostatin, CXCL4 and VCAM-1 as biomarkers of lupus nephritis
Chi Chiu Mok, Samar Soliman, Ling Yin Ho, Fatma A. Mohamed, Faten Ismail Mohamed, Chandra Mohan
The predictive prognostic factors for polymyositis/dermatomyositis-associated interstitial lung disease
Yumiko Sugiyama, Ryusuke Yoshimi, Maasa Tamura, Mitsuhiro Takeno, Yosuke Kunishita, Daiga Kishimoto, Yuji Yoshioka, Kouji Kobayashi, Kaoru Takase-Minegishi, Toshiyuki Watanabe, Naoki Hamada, Hideto Nagai, Naomi Tsuchida, Yutaro Soejima, Hiroto Nakano, Reikou Kamiyama, Takeaki Uehara, Yohei Kirino, Akiko Sekiguchi, Atsushi Ihata, Shigeru Ohno, Shouhei Nagaoka, Hideaki Nakajima
Predictors of remission with etanercept-methotrexate induction therapy and loss of remission with etanercept maintenance, reduction, or withdrawal in moderately active rheumatoid arthritis: results of the PRESERVE trial
Josef S. Smolen, Annette Szumski, Andrew S. Koenig, Thomas V. Jones, Lisa Marshall
BANK1 alters B cell responses and influences the interactions between B cells and induced T regulatory cells in mice with collagen-induced arthritis
Jie Yang, Jie Ren, Yiming Yang, Juan Sun, Xiaohui Zhou, Shucong Zheng, Dandan Xuan, Yu Xue, Huimin Fan, Jiong Zhang, Hejian Zou, Weiguo Wan, Ning Kong
Highly selective inhibition of Bruton’s tyrosine kinase attenuates skin and brain disease in murine lupus
Samantha A. Chalmers, Jing Wen, Jessica Doerner, Ariel Stock, Carla M. Cuda, Hadijat M. Makinde, Harris Perlman, Todd Bosanac, Deborah Webb, Gerald Nabozny, Jay S. Fine, Elliott Klein, Meera Ramanujam, Chaim Putterman
Ultrasonography and magnetic resonance imaging changes in patients with polymyalgia rheumatica treated by tocilizumab
Anaïs Huwart, Florent Garrigues, Sandrine Jousse-Joulin, Thierry Marhadour, Dewi Guellec, Divi Cornec, Maelenn Gouillou, Alain Saraux, Valérie Devauchelle-Pensec
Treatment of immunoglobulin G4-related sialadenitis: outcomes of glucocorticoid therapy combined with steroid-sparing agents
Xia Hong, Yan-Yan Zhang, Wei Li, Yan-Ying Liu, Zhen Wang, Yan Chen, Yan Gao, Zhi-Peng Sun, Xin Peng, Jia-Zeng Su, Zhi-Gang Cai, Lei Zhang, Jing He, Li-Min Ren, Hong-Yu Yang, Zhan-Guo Li, Guang-Yan Yu
Increase of MZB1 in B cells in systemic lupus erythematosus: proteomic analysis of biopsied lymph nodes
Aya Miyagawa-Hayashino, Hajime Yoshifuji, Koji Kitagori, Shinji Ito, Takuma Oku, Yoshitaka Hirayama, Adeeb Salah, Toshiki Nakajima, Kaori Kiso, Norishige Yamada, Hironori Haga, Tatsuaki Tsuruyama
Age and fecal microbial strain-specific differences in patients with spondyloarthritis
Matthew L. Stoll, Pamela F. Weiss, Jennifer E. Weiss, Peter A. Nigrovic, Barbara S. Edelheit, S. Lou Bridges Jr, Maria I. Danila, Charles H. Spencer, Marilynn G. Punaro, Kenneth Schikler, Andreas Reiff, Ranjit Kumar, Randy Q. Cron, Casey D. Morrow, Elliot J. Lefkowitz
Can baseline ultrasound results help to predict failure to achieve DAS28 remission after 1 year of tight control treatment in early RA patients?
D. F. Ten Cate, J. W. G. Jacobs, W. A. A. Swen, J. M. W. Hazes, M. H. de Jager, N. M. Basoski, C. J. Haagsma, J. J. Luime, A. H. Gerards
Anti-CCP-positive patients with RA have a higher 10-year probability of fracture evaluated by FRAX®: a registry study of RA with osteoporosis/fracture
Tien-Tsai Cheng, Shan-Fu Yu, Fu-Mei Su, Yin-Chou Chen, Ben Yu-Jih Su, Wen-Chan Chiu, Chung-Yuan Hsu, Jia-Feng Chen, Chi-Hua Ko, Han-Ming Lai
Systemic sclerosis associated interstitial lung disease - individualized immunosuppressive therapy and course of lung function: results of the EUSTAR group
Sabine Adler, Dörte Huscher, Elise Siegert, Yannick Allanore, László Czirják, Francesco DelGaldo, Christopher P. Denton, Oliver Distler, Marc Frerix, Marco Matucci-Cerinic, Ulf Mueller-Ladner, Ingo-Helmut Tarner, Gabriele Valentini, Ulrich A. Walker, Peter M. Villiger, Gabriela Riemekasten
Synovial IL-9 facilitates neutrophil survival, function and differentiation of Th17 cells in rheumatoid arthritis
Kaustav Chowdhury, Uma Kumar, Soumabha Das, Jaydeep Chaudhuri, Prabin Kumar, Maumita Kanjilal, Parashar Ghosh, Geetabali Sircar, Ravi Kiran Basyal, Uma Kanga, Santu Bandyopadhaya, Dipendra Kumar Mitra
The new aims and scope of Arthritis Research & Therapy
Christopher D. Buckley, Harris Perlman
Soluble uric acid increases PDZK1 and ABCG2 expression in human intestinal cell lines via the TLR4-NLRP3 inflammasome and PI3K/Akt signaling pathway
Mo Chen, Xiaoyong Lu, Ci Lu, Ning Shen, Yujie Jiang, Menglu Chen, Huaxiang Wu
Altered white matter microstructure in lupus patients: a diffusion tensor imaging study
Jessika Nystedt, Markus Nilsson, Andreas Jönsen, Petra Nilsson, Anders Bengtsson, Åsa Lilja, Jimmy Lätt, Peter Mannfolk, Pia C Sundgren
Recurrent anterior uveitis and subsequent incidence of ankylosing spondylitis: a nationwide cohort study from 2002 to 2013
Baek-Lok Oh, Jeong Seok Lee, Eun Young Lee, Hee Young Lee, Hyeong Gon Yu
Fli1-haploinsufficient dermal fibroblasts promote skin-localized transdifferentiation of Th2-like regulatory T cells
Ryosuke Saigusa, Yoshihide Asano, Takashi Taniguchi, Megumi Hirabayashi, Kouki Nakamura, Shunsuke Miura, Takashi Yamashita, Takehiro Takahashi, Yohei Ichimura, Tetsuo Toyama, Ayumi Yoshizaki, Maria Trojanowska, Shinichi Sato
Abatacept blocks anti-citrullinated protein antibody and rheumatoid factor mediated cytokine production in human macrophages in IDO-dependent manner
Aline Bozec, Yubin Luo, Cecilia Engdahl, Camille Figueiredo, Holger Bang, Georg Schett
Anti-CD11b antibody treatment suppresses the osteoclast generation, inflammatory cell infiltration, and autoantibody production in arthritis-prone FcγRIIB-deficient mice
Mareki Ohtsuji, Qingshun Lin, Hideki Okazaki, Kazuko Takahashi, Hirofumi Amano, Hideo Yagita, Hiroyuki Nishimura, Sachiko Hirose
Adiponectin aggravates bone erosion by promoting osteopontin production in synovial tissue of rheumatoid arthritis
Jie Qian, Lingxiao Xu, Xiaoxuan Sun, Yani Wang, Wenhua Xuan, Qian Zhang, Pengfei Zhao, Qin Wu, Rui Liu, Nan Che, Fang Wang, Wenfeng Tan, Miaojia Zhang
IL-1 family cytokines and soluble receptors in systemic lupus erythematosus
Paola Italiani, Maria Laura Manca, Francesca Angelotti, Daniela Melillo, Federico Pratesi, Ilaria Puxeddu, Diana Boraschi, Paola Migliorini
Response to: “Monosodium urate crystal deposition associated with the progress of radiographic grade at the sacroiliac joint in axial SpA: a dual-energy CT study”
Andrea S. Klauser, Johann Gruber
Thinking BIG rheumatology: how to make functional genomics data work for you
Deborah R. Winter
Identification of a novel autoantibody against self-vimentin specific in secondary Sjögren’s syndrome
Yu-Hui Li, Ya-Ping Gao, Jie Dong, Lian-Jie Shi, Xiao-Lin Sun, Ru Li, Xue-Wu Zhang, Yu Liu, Li Long, Jing He, Qun-Jie Zhong, Eric Morand, Guang Yang, Zhan-Guo Li
A unique role for galectin-9 in angiogenesis and inflammatory arthritis
Martin J. O’Brien, Qiang Shu, W.Alexander Stinson, Pei-Suen Tsou, Jeffrey H. Ruth, Takeo Isozaki, Phillip L. Campbell, Ray A. Ohara, Alisa E. Koch, David A. Fox, M. Asif Amin
Correction to: Patients and surgeons provide endorsement of core domains for total joint replacement clinical trials
Anh Hoang, Susan M. Goodman, Iris Y. Navarro-Millán, Lisa A. Mandl, Mark P. Figgie, Mathias P. Bostrom, Douglas E. Padgett, Peter K. Sculco, Alexander S. McLawhorn, Jasvinder A. Singh
Baseline autoantibody profile in rheumatoid arthritis is associated with early treatment response but not long-term outcomes
Emma C. de Moel, Veerle F. A. M. Derksen, Gerrie Stoeken, Leendert A. Trouw, Holger Bang, Robbert J. Goekoop, Irene Speyer, Tom W. J. Huizinga, Cornelia F. Allaart, René E. M. Toes, Diane van der Woude
MicroRNA-302b negatively regulates IL-1β production in response to MSU crystals by targeting IRAK4 and EphA2
Teng Ma, Xiao Liu, Zhifu Cen, Chuan Xin, Mingfeng Guo, Chaoyu Zou, Wenpeng Song, Rou Xie, Kailun Wang, Hong Zhou, Jun Zhang, Zhen Wang, Ce Bian, Kaijun Cui, Jiong Li, Yu-Quan Wei, Jing Li, Xikun Zhou
Impaired lymph node stromal cell function during the earliest phases of rheumatoid arthritis
Janine S. Hähnlein, Reza Nadafi, Tineke de Jong, Tamara H. Ramwadhdoebe, Johanna F. Semmelink, Karen I. Maijer, IJsbrand A. Zijlstra, Mario Maas, Danielle M. Gerlag, Teunis B. H. Geijtenbeek, Paul P. Tak, Reina E. Mebius, Lisa G. M. van Baarsen
Autoimmune reactivity to malondialdehyde adducts in systemic lupus erythematosus is associated with disease activity and nephritis
Uta Hardt, Anders Larsson, Iva Gunnarsson, Robert M. Clancy, Michelle Petri, Jill P. Buyon, Gregg J. Silverman, Elisabet Svenungsson, Caroline Grönwall
Longitudinal stability of fibromyalgia symptom clusters
Tanya L. Hoskin, Mary O. Whipple, Sanjeev Nanda, Ann Vincent
Anti-CD74 antibodies have no diagnostic value in early axial spondyloarthritis: data from the spondyloarthritis caught early (SPACE) cohort
Janneke J. de Winter, Marleen G. van de Sande, Niklas Baerlecken, Inger Berg, Roberta Ramonda, Désirée van der Heijde, Floris A. van Gaalen, Torsten Witte, Dominique L. Baeten
Pharmacological characterisation of CR6086, a potent prostaglandin E2 receptor 4 antagonist, as a new potential disease-modifying anti-rheumatic drug
Gianfranco Caselli, Albino Bonazzi, Marco Lanza, Flora Ferrari, Daniele Maggioni, Cristian Ferioli, Roberto Giambelli, Eleonora Comi, Silvia Zerbi, Marco Perrella, Ornella Letari, Elena Di Luccio, Milena Colovic, Stefano Persiani, Tiziano Zanelli, Laura Mennuni, Tiziana Piepoli, Lucio Claudio Rovati
Exploring determinants predicting response to intra-articular hyaluronic acid treatment in symptomatic knee osteoarthritis: 9-year follow-up data from the Osteoarthritis Initiative
Jean-Pierre Pelletier, Jean-Pierre Raynauld, François Abram, Marc Dorais, Philippe Delorme, Johanne Martel-Pelletier
Integrating genome-wide DNA methylation and mRNA expression profiles identified different molecular features between Kashin-Beck disease and primary osteoarthritis
Yan Wen, Ping Li, Jingcan Hao, Chen Duan, Jing Han, Awen He, Yanan Du, Li Liu, Xiao Liang, Feng Zhang, Xiong Guo
Sirukumab in rheumatoid arthritis refractory to sulfasalazine or methotrexate: a randomized phase 3 safety and efficacy study in Japanese patients
Tsutomu Takeuchi, Hisashi Yamanaka, Masayoshi Harigai, Ryo Tamamura, Yuichi Kato, Yoshifumi Ukyo, Toshikazu Nakano, Benjamin Hsu, Yoshiya Tanaka
Traditional Chinese medicine formula Bi-Qi capsule alleviates rheumatoid arthritis-induced inflammation, synovial hyperplasia, and cartilage destruction in rats
Kai Wang, Dongmei Zhang, Yan Liu, Xuan Wang, Jiantong Zhao, Tingting Sun, Tingting Jin, Baoli Li, Janak L. Pathak
Hypogalactosylation of immunoglobulin G in rheumatoid arthritis: relationship to HLA-DRB1 shared epitope, anticitrullinated protein antibodies, rheumatoid factor, and correlation with inflammatory activity
Christian Schwedler, Thomas Häupl, Ulrich Kalus, Véronique Blanchard, Gerd-Rüdiger Burmester, Denis Poddubnyy, Berthold Hoppe
Mice with miR-146a deficiency develop severe gouty arthritis via dysregulation of TRAF 6, IRAK 1 and NALP3 inflammasome
Quan-Bo Zhang, Yu-Feng Qing, Cong-Cong Yin, Li Zhou, Xian-shuang Liu, Qing-Sheng Mi, Jing-Guo Zhou
Blockade of TGF-β/Smad signaling by the small compound HPH-15 ameliorates experimental skin fibrosis
Vu Huy Luong, Takenao Chino, Noritaka Oyama, Takashi Matsushita, Yoko Sasaki, Dai Ogura, Shin-ichiro Niwa, Tanima Biswas, Akiyuki Hamasaki, Mikako Fujita, Yoshinari Okamoto, Masami Otsuka, Hironobu Ihn, Minoru Hasegawa
Efficacy and safety of secukinumab administration by autoinjector in patients with psoriatic arthritis: results from a randomized, placebo-controlled trial (FUTURE 3)
Peter Nash, Philip J. Mease, Iain B. McInnes, Proton Rahman, Christopher T. Ritchlin, Ricardo Blanco, Eva Dokoupilova, Mats Andersson, Radhika Kajekar, Shephard Mpofu, Luminita Pricop
Pain sensitivity at rest and during muscle contraction in persons with rheumatoid arthritis: a substudy within the Physical Activity in Rheumatoid Arthritis 2010 study
Monika Löfgren, Christina H. Opava, Ingrid Demmelmaier, Cecilia Fridén, Ingrid E. Lundberg, Birgitta Nordgren, Eva Kosek
Methotrexate inhibits effects of platelet-derived growth factor and interleukin-1β on rheumatoid arthritis fibroblast-like synoviocytes
Beatrice Bergström, Hans Carlsten, Anna-Karin Hultgård Ekwall
Risk factors for oral methotrexate failure in patients with inflammatory polyarthritis: results from a UK prospective cohort study
James Bluett, Jamie C. Sergeant, Alex J. MacGregor, Jacqueline R. Chipping, Tarnya Marshall, Deborah P. M. Symmons, Suzanne M. M. Verstappen
Myocellular characteristics in rheumatoid arthritis and osteoarthritis patients
Sandro Manuel Mueller, David Aguayo, Daniel Aeberli, Esther Vögelin, Marco Toigo
Antibodies against chemokine receptors CXCR3 and CXCR4 predict progressive deterioration of lung function in patients with systemic sclerosis
Florian Weigold, Jeannine Günther, Moritz Pfeiffenberger, Otavio Cabral-Marques, Elise Siegert, Duska Dragun, Aurélie Philippe, Ann-Katrin Regensburger, Andreas Recke, Xinhua Yu, Frank Petersen, Rusan Catar, Robert Biesen, Falk Hiepe, Gerd R. Burmester, Harald Heidecke, Gabriela Riemekasten
Impact of diuretics on the urate lowering therapy in patients with gout: analysis of an inception cohort
Laura Ranieri, Carolina Contero, Maria-Luisa Peral, Irene Calabuig, Pedro Zapater, Mariano Andres
Interleukin-37 is increased in adult-onset Still’s disease and associated with disease activity
Huihui Chi, Dongzhou Liu, Yue Sun, Qiongyi Hu, Honglei Liu, Xiaobing Cheng, Junna Ye, Hui Shi, Yufeng Yin, Mengru Liu, Xinyao Wu, Zhuochao Zhou, Jialin Teng, Chengde Yang, Yutong Su
Methotrexate upregulates circadian transcriptional factors PAR bZIP to induce apoptosis on rheumatoid arthritis synovial fibroblasts
Kohjin Suzuki, Kohsuke Yoshida, Takeshi Ueha, Kenta Kaneshiro, Ayako Nakai, Naonori Hashimoto, Koto Uchida, Teppei Hashimoto, Yoshiko Kawasaki, Nao Shibanuma, Natsuko Nakagawa, Yoshitada Sakai, Akira Hashiramoto
Feasibility and reliability of the Spondyloarthritis Research Consortium of Canada sacroiliac joint inflammation score in children
Pamela F. Weiss, Walter P. Maksymowych, Robert G. Lambert, Jacob L. Jaremko, David M. Biko, Joel Paschke, Timothy G. Brandon, Rui Xiao, Nancy A. Chauvin
Effect of filgotinib, a selective JAK 1 inhibitor, with and without methotrexate in patients with rheumatoid arthritis: patient-reported outcomes
Mark Genovese, Rene Westhovens, Luc Meuleners, Annegret Van der Aa, Pille Harrison, Chantal Tasset, Arthur Kavanaugh
Smoking is not linked to the development of anti-peptidylarginine deiminase 4 autoantibodies in rheumatoid arthritis
Laura C. Cappelli, Maximilian F. Konig, Allan C. Gelber, Clifton O. Bingham III, Erika Darrah
Effectiveness and safety of tofacitinib in rheumatoid arthritis: a cohort study
Marina Amaral de Ávila Machado, Cristiano Soares de Moura, Steve Ferreira Guerra, Jeffrey R. Curtis, Michal Abrahamowicz, Sasha Bernatsky
Clinical and MRI remission in patients with nonradiographic axial spondyloarthritis who received long-term open-label adalimumab treatment: 3-year results of the ABILITY-1 trial
Désirée van der Heijde, Joachim Sieper, Walter P. Maksymowych, Robert G. Lambert, Su Chen, Maja Hojnik, Jaclyn K. Anderson, Aileen L. Pangan
CCL17 blockade as a therapy for osteoarthritis pain and disease
Ming-Chin Lee, Reem Saleh, Adrian Achuthan, Andrew J. Fleetwood, Irmgard Förster, John A. Hamilton, Andrew D. Cook
Anti-CCP antibodies and bone
Giovanni Orsolini, Ombretta Viapiana, Maurizio Rossini, Giovanni Adami, Cristian Caimmi, Angelo Fassio, Davide Gatti
Dysregulated heme oxygenase-1low M2-like macrophages augment lupus nephritis via Bach1 induced by type I interferons
Daiga Kishimoto, Yohei Kirino, Maasa Tamura, Mitsuhiro Takeno, Yosuke Kunishita, Kaoru Takase-Minegishi, Hiroto Nakano, Ikuma Kato, Kiyotaka Nagahama, Ryusuke Yoshimi, Kazuhiko Igarashi, Ichiro Aoki, Hideaki Nakajima
Failure of remission induction by glucocorticoids alone or in combination with immunosuppressive agents in IgG4-related disease: a prospective study of 215 patients
Liwen Wang, Panpan Zhang, Mu Wang, Ruie Feng, Yamin Lai, Linyi Peng, Yunyun Fei, Xuan Zhang, Yan Zhao, Xiaofeng Zeng, Fengchun Zhang, Wen Zhang
Identification of novel biomarker as citrullinated inter-alpha-trypsin inhibitor heavy chain 4, specifically increased in sera with experimental and rheumatoid arthritis
Hoshimi Kawaguchi, Isao Matsumoto, Atsumu Osada, Izumi Kurata, Hiroshi Ebe, Yuki Tanaka, Asuka Inoue, Naoto Umeda, Yuya Kondo, Hiroto Tsuboi, Yasuhiro Shinkai, Yoshito Kumagai, Akihito Ishigami, Takayuki Sumida
Osteoclasts degrade bone and cartilage knee joint compartments through different resorption processes
Henrik Löfvall, Hannah Newbould, Morten A. Karsdal, Morten H. Dziegiel, Johan Richter, Kim Henriksen, Christian S. Thudium
Does the presence of magnetic resonance imaging-detected osteitis at diagnosis with rheumatoid arthritis lower the risk for achieving disease-modifying antirheumatic drug-free sustained remission: results of a longitudinal study
L. E. Burgers, D. M. Boeters, M. Reijnierse, A. H. M. van der Helm-van Mil
Phenome-wide association study identifies marked increased in burden of comorbidities in African Americans with systemic lupus erythematosus
April Barnado, Robert J. Carroll, Carolyn Casey, Lee Wheless, Joshua C. Denny, Leslie J. Crofford
Comparison of the impact of Tripterygium wilfordii Hook F and Methotrexate treatment on radiological progression in active rheumatoid arthritis: 2-year follow up of a randomized, non-blinded, controlled study
Yang-zhong Zhou, Li-dan Zhao, Hua Chen, Yan Zhang, Dan-feng Wang, Lin-fang Huang, Qian-wen Lv, Bin Liu, Zhenbin Li, Wei Wei, Hongbin Li, Xiangping Liao, Hui Liu, Xiumei Liu, Hongtao Jin, Junxiang Wang, Yun-yun Fei, Qing-jun Wu, Wen Zhang, Qun Shi, Wen-jie Zheng, Feng-chun Zhang, Fu-lin Tang, Peter E. Lipsky, Xuan Zhang
Correction to: identification of multiple cancer-associated myositis-specific autoantibodies in idiopathic inflammatory myopathies: a large longitudinal cohort study
Hanbo Yang, Qinglin Peng, Liguo Yin, Shanshan Li, Jingli Shi, Yamei Zhang, Xin Lu, Xiaoming Shu, Sigong Zhang, Guochun Wang
Effect of combined treatment with bisphosphonate and vitamin D on atherosclerosis in patients with systemic lupus erythematosus: a propensity score-based analysis
Kazumasa Ohmura, Masaru Kato, Toshiyuki Watanabe, Kenji Oku, Toshiyuki Bohgaki, Tetsuya Horita, Shinsuke Yasuda, Yoichi M. Ito, Norihiro Sato, Tatsuya Atsumi
Inflammatory back pain in psoriatic arthritis is significantly more responsive to corticosteroids compared to back pain in ankylosing spondylitis: a prospective, open-labelled, controlled pilot study
Muhammad Haroon, Muddassar Ahmad, Muhammad Nouman Baig, Olivia Mason, John Rice, Oliver FitzGerald
Effect of a low-intensity, self-management lifestyle intervention on knee pain in community-based young to middle-aged rural women: a cluster randomised controlled trial
Yuanyuan Wang, Catherine Lombard, Sultana Monira Hussain, Cheryce Harrison, Samantha Kozica, Sharmayne R. E. Brady, Helena Teede, Flavia M. Cicuttini
Characterization of inflammatory cell infiltrate of scleroderma skin: B cells and skin score progression
Silvia Bosello, Cristiana Angelucci, Gina Lama, Stefano Alivernini, Gabriella Proietti, Barbara Tolusso, Gigliola Sica, Elisa Gremese, Gianfranco Ferraccioli
Association between general joint hypermobility and knee, hip, and lumbar spine osteoarthritis by race: a cross-sectional study
Portia P. E. Flowers, Rebecca J. Cleveland, Todd A. Schwartz, Amanda E. Nelson, Virginia B. Kraus, Howard J. Hillstrom, Adam P. Goode, Marian T. Hannan, Jordan B. Renner, Joanne M. Jordan, Yvonne M. Golightly
Effects of selexipag and its active metabolite in contrasting the profibrotic myofibroblast activity in cultured scleroderma skin fibroblasts
Maurizio Cutolo, Barbara Ruaro, Paola Montagna, Renata Brizzolara, Emanuela Stratta, Amelia Chiara Trombetta, Stefano Scabini, Pier Paolo Tavilla, Aurora Parodi, Claudio Corallo, Nicola Giordano, Sabrina Paolino, Carmen Pizzorni, Alberto Sulli, Vanessa Smith, Stefano Soldano
Accuracy of the HumaSensplus point-of-care uric acid meter using capillary blood obtained by fingertip puncture
Stéphanie Fabre, Pierre Clerson, Jean-Marie Launay, Jean-François Gautier, Tiphaine Vidal-Trecan, Jean-Pierre Riveline, Adam Platt, Anna Abrahamsson, Jeffrey N. Miner, Glen Hughes, Pascal Richette, Thomas Bardin
Factors associated with physicians’ prescriptions for rheumatoid arthritis drugs not filled by patients
Hong J. Kan, Kirill Dyagilev, Peter Schulam, Suchi Saria, Hadi Kharrazi, David Bodycombe, Charles T. Molta, Jeffrey R. Curtis
Fcγ receptor-mediated influx of S100A8/A9-producing neutrophils as inducer of bone erosion during antigen-induced arthritis
Irene Di Ceglie, Giuliana Ascone, Niels A. J. Cremers, Annet W. Sloetjes, Birgitte Walgreen, Thomas Vogl, Johannes Roth, J. Sjef Verbeek, Fons A. J. van de Loo, Marije I. Koenders, Peter M. van der Kraan, Arjen B. Blom, Martijn H. J. van den Bosch, Peter L. E. M. van Lent
Deleterious role of hepatitis B virus infection in therapeutic response among patients with rheumatoid arthritis in a clinical practice setting: a case-control study
Yu-Lan Chen, Jian-Zi Lin, Ying-Qian Mo, Jian-Da Ma, Qian-Hua Li, Xiao-Ying Wang, Ze-Hong Yang, Tao Yan, Dong-Hui Zheng, Lie Dai
Smoking, body mass index, disease activity, and the risk of rapid radiographic progression in patients with early rheumatoid arthritis
Emil Rydell, Kristina Forslind, Jan-Åke Nilsson, Lennart T. H. Jacobsson, Carl Turesson
Targeted lipidomics analysis identified altered serum lipid profiles in patients with polymyositis and dermatomyositis
Joan Raouf, Helena Idborg, Petter Englund, Helene Alexanderson, Maryam Dastmalchi, Per-Johan Jakobsson, Ingrid E. Lundberg, Marina Korotkova
Estrogen induces St6gal1 expression and increases IgG sialylation in mice and patients with rheumatoid arthritis: a potential explanation for the increased risk of rheumatoid arthritis in postmenopausal women
Cecilia Engdahl, Albert Bondt, Ulrike Harre, Jasmin Raufer, René Pfeifle, Alessandro Camponeschi, Manfred Wuhrer, Michaela Seeling, Inga-Lill Mårtensson, Falk Nimmerjahn, Gerhard Krönke, Hans U. Scherer, Helena Forsblad-d’Elia, Georg Schett
Integrative analysis reveals CD38 as a therapeutic target for plasma cell-rich pre-disease and established rheumatoid arthritis and systemic lupus erythematosus
Suzanne Cole, Alice Walsh, Xuefeng Yin, Mihir D. Wechalekar, Malcolm D. Smith, Susanna M. Proudman, Douglas J. Veale, Ursula Fearon, Costantino Pitzalis, Frances Humby, Michele Bombardieri, Amy Axel, Homer Adams III, Christopher Chiu, Michael Sharp, John Alvarez, Ian Anderson, Loui Madakamutil, Sunil Nagpal, Yanxia Guo
Early achievement of deep remission predicts low incidence of renal flare in lupus nephritis class III or IV
Hironari Hanaoka, Harunobu Iida, Tomofumi Kiyokawa, Yukiko Takakuwa, Kimito Kawahata
Two independent proteomic approaches provide a comprehensive analysis of the synovial fluid proteome response to Autologous Chondrocyte Implantation
Charlotte H. Hulme, Emma L. Wilson, Heidi R. Fuller, Sally Roberts, James B. Richardson, Pete Gallacher, Mandy J. Peffers, Sally L. Shirran, Catherine H. Botting, Karina T. Wright
Upper zone of growth plate and cartilage matrix associated protein protects cartilage during inflammatory arthritis
Fritz Seuffert, Daniela Weidner, Wolfgang Baum, Georg Schett, Michael Stock
Inflammation functions as a key mediator in the link between ACPA and erosion development: an association study in Clinically Suspect Arthralgia
R. M. ten Brinck, R. E. M. Toes, A. H. M. van der Helm–van Mil
Untangling the complex relationships between incident gout risk, serum urate, and its comorbidities
Mengying Sun, Ana I. Vazquez, Richard J. Reynolds, Jasvinder A. Singh, Mathew Reeves, Tony R. Merriman, Angelo L. Gaffo, Gustavo de los Campos
Predicting unfavorable long-term outcome in juvenile idiopathic arthritis: results from the Nordic cohort study
Veronika Rypdal, Ellen Dalen Arnstad, Kristiina Aalto, Lillemor Berntson, Maria Ekelund, Anders Fasth, Mia Glerup, Troels Herlin, Susan Nielsen, Suvi Peltoniemi, Marek Zak, Marite Rygg, Martin Rypdal, Ellen Nordal, Gudmund Marhaug, Freddy Karup Pedersen, Pekka Lahdenne, Boel Anderson-Gäre, Nils Thomas Songstad, Astri Lang, Anne Elisabeth Ross, Kjell Berntzen, Nina Moe, Mikael Damgaard, Nils Olof Jonsson, Anders Berner, Hans Ekström, Eric Ronge, Agne Lind, Lars Hammarèn, Johan Robinsson, Anna-Lena Nilsson
Meta-analysis of GWAS on both Chinese and European populations identifies GPR173 as a novel X chromosome susceptibility gene for SLE
Huoru Zhang, Yan Zhang, Yong-Fei Wang, David Morris, Nattiya Hirankarn, Yujun Sheng, Jiangshan Shen, Hai-Feng Pan, Jing Yang, Sen Yang, Yong Cui, Dong-Qing Ye, Timothy J. Vyse, Xuejun Zhang, Yu Lung Lau, Wanling Yang
Does psychological stress in patients with clinically suspect arthralgia associate with subclinical inflammation and progression to inflammatory arthritis?
Aleid C. Boer, Robin M. ten Brinck, Andrea W. M. Evers, Annette H. M. van der Helm-van Mil
Does information on novel identified autoantibodies contribute to predicting the progression from undifferentiated arthritis to rheumatoid arthritis: a study on anti-CarP antibodies as an example
Debbie M. Boeters, Leendert A. Trouw, Annette H. M. van der Helm-van Mil, Hanna W. van Steenbergen
Oxidative stress impairs energy metabolism in primary cells and synovial tissue of patients with rheumatoid arthritis
Emese Balogh, Douglas J. Veale, Trudy McGarry, Carl Orr, Zoltan Szekanecz, Chin-Teck Ng, Ursula Fearon, Monika Biniecka
Fatigue independently predicts different work disability dimensions in etanercept-treated rheumatoid arthritis and ankylosing spondylitis patients
Katie L. Druce, Laraine Aikman, Maria Dilleen, Annie Burden, Piotr Szczypa, Neil Basu
The lack of association between the burden of monosodium urate crystals assessed with dual-energy computed tomography or ultrasonography with cardiovascular risk in the commonly high-risk gout patient
Tristan Pascart, Benoist Capon, Agathe Grandjean, Julie Legrand, Nasser Namane, Vincent Ducoulombier, Marguerite Motte, Marie Vandecandelaere, Hélène Luraschi, Catherine Godart, Eric Houvenagel, Laurène Norberciak, Jean-François Budzik
Transcription factor motif enrichment in whole transcriptome analysis identifies STAT4 and BCL6 as the most prominent binding motif in systemic juvenile idiopathic arthritis
Boris Hügle, Anastasia Schippers, Nadine Fischer, Kim Ohl, Bernd Denecke, Fabio Ticconi, Bas Vastert, Ivan G. Costa, Johannes-Peter Haas, Klaus Tenbrock
Efficacy and safety of febuxostat extended release and immediate release in patients with gout and moderate renal impairment: phase II placebo-controlled study
Lhanoo Gunawardhana, Michael A. Becker, Andrew Whelton, Barbara Hunt, Majin Castillo, Kenneth Saag
Genome-wide association study meta-analysis identifies five new loci for systemic lupus erythematosus
Antonio Julià, Francisco Javier López-Longo, José J. Pérez Venegas, Silvia Bonàs-Guarch, Àlex Olivé, José Luís Andreu, Mª. Ángeles Aguirre-Zamorano, Paloma Vela, Joan M. Nolla, José Luís Marenco de la Fuente, Antonio Zea, José María Pego-Reigosa, Mercedes Freire, Elvira Díez, Esther Rodríguez-Almaraz, Patricia Carreira, Ricardo Blanco, Víctor Martínez Taboada, María López-Lasanta, Mireia López Corbeto, Josep M. Mercader, David Torrents, Devin Absher, Sara Marsal, Antonio Fernández-Nebro
From supernatants to cytokines: a personal view on the early history of IL-1, IL-1Ra, TNF and its inhibitor in rheumatology
Jean-Michel Dayer
Comparison of US patient, rheumatologist, and dermatologist perceptions of psoriatic disease symptoms: results from the DISCONNECT study
M. Elaine Husni, Anthony Fernandez, Brett Hauber, Rakesh Singh, Joshua Posner, Jessie Sutphin, Arijit Ganguli
Methotrexate: who would have predicted its importance in rheumatoid arthritis?
Michael E. Weinblatt
Calcification of the acetabular labrum of the hip: prevalence in the general population and relation to hip articular cartilage and fibrocartilage degeneration
Thelonius Hawellek, Jan Hubert, Sandra Hischke, Matthias Krause, Jessica Bertrand, Burkhard C. Schmidt, Andreas Kronz, Klaus Püschel, Wolfgang Rüther, Andreas Niemeier
The course of pain hypersensitivity according to painDETECT in patients with rheumatoid arthritis initiating treatment: results from the prospective FRAME-cohort study
Signe Rifbjerg-Madsen, Anton Wulf Christensen, Mikael Boesen, Robin Christensen, Bente Danneskiold-Samsøe, Henning Bliddal, Lene Dreyer, Henning Locht, Kirstine Amris
The majority of patients with newly diagnosed juvenile idiopathic arthritis achieve a health-related quality of life that is similar to that of healthy peers: results of the German multicenter inception cohort (ICON)
Miriam Listing, Kirsten Mönkemöller, Ina Liedmann, Martina Niewerth, Claudia Sengler, Joachim Listing, Dirk Foell, Arnd Heiligenhaus, Ariane Klein, Gerd Horneff, Gerd Ganser, Johannes-Peter Haas, Jens Klotsche, Kirsten Minden
Association between inflammation and systolic blood pressure in RA compared to patients without RA
Zhi Yu, Seoyoung C. Kim, Kathleen Vanni, Jie Huang, Rishi Desai, Shawn N. Murphy, Daniel H. Solomon, Katherine P. Liao
Comorbidity in gout at the time of first diagnosis: sex differences that may have implications for dosing of urate lowering therapy
Panagiota Drivelegka, Valgerdur Sigurdardottir, Anna Svärd, Lennart T. H. Jacobsson, Mats Dehlin
Gout and the risk of myocardial infarction in older adults: a study of Medicare recipients
Jasvinder A. Singh, John D. Cleveland
How patients with gout become engaged in disease management: a constructivist grounded theory study
Alyssa Howren, Susan M. Cox, Kam Shojania, Sharan K. Rai, Hyon K. Choi, Mary A. De Vera
Metabolomics approach by 1H NMR spectroscopy of serum reveals progression axes for asymptomatic hyperuricemia and gout
Yannan Zhang, Huanzhen Zhang, Dong Chang, Fuchuan Guo, Hongzhi Pan, Yuexin Yang
The effects of upper and lower limb exercise on the microvascular reactivity in limited cutaneous systemic sclerosis patients
A. Mitropoulos, A. Gumber, H. Crank, M. Akil, M. Klonizakis
Secukinumab provides rapid and sustained pain relief in psoriatic arthritis over 2 years: results from the FUTURE 2 study
Iain B. McInnes, Philip J. Mease, Georg Schett, Bruce Kirkham, Vibeke Strand, Nicole Williams, Todd Fox, Luminita Pricop, Steffen M. Jugl, Kunal K. Gandhi
Role of CXCL13 and CCL20 in the recruitment of B cells to inflammatory foci in chronic arthritis
Estefanía Armas-González, María Jesús Domínguez-Luis, Ana Díaz-Martín, Mayte Arce-Franco, Javier Castro-Hernández, Gabriela Danelon, Vanesa Hernández-Hernández, Sagrario Bustabad-Reyes, Alberto Cantabrana, Mariagrazia Uguccioni, Federico Díaz-González
IL-17A induces osteoblast differentiation by activating JAK2/STAT3 in ankylosing spondylitis
Sungsin Jo, Sung Eun Wang, Young Lim Lee, Suman Kang, Bitnara Lee, Jinil Han, Il-Hoon Sung, Ye-Soo Park, Sang-Cheol Bae, Tae-Hwan Kim
H1-antihistamines are associated with lower prevalence of radiographic knee osteoarthritis: a cross-sectional analysis of the Osteoarthritis Initiative data
Ivan Shirinsky, Valery Shirinsky
Genetic background may contribute to the latitude-dependent prevalence of dermatomyositis and anti-TIF1-γ autoantibodies in adult patients with myositis
Joanna E. Parkes, Simon Rothwell, Alexander Oldroyd, Hector Chinoy, Janine A. Lamb, Ingrid E. Lundberg, Frederick W. Miller, Robert G. Cooper, William E. Ollier, Peter K. Gregersen, Jiri Vencovsky, Katalin Danko, Vidya Limaye, Albert Selva-O’Callaghan, Pedro M. Machado, Michael G. Hanna, Hazel Platt, Øyvind Molberg, Olivier Benveniste, Timothy Radstake, Jan De Bleecker, Boel De Paepe, Britta Maurer, Leonid Padyukov, Terrance P. O’Hanlon, Lucy R. Wedderburn, Christopher Denton, Herman Mann, David Hilton-Jones, Patrick Kiely, Paul H. Plotz, Mark Gourley, Galina Marder, Neil J. McHugh, Zoe E. Betteridge
CircIBTK inhibits DNA demethylation and activation of AKT signaling pathway via miR-29b in peripheral blood mononuclear cells in systemic lupus erythematosus
Xin Wang, Chengzhong Zhang, Zhouwei Wu, Yue Chen, Weimin Shi
Smoking-induced aggravation of experimental arthritis is dependent of aryl hydrocarbon receptor activation in Th17 cells
Jhimmy Talbot, Raphael S. Peres, Larissa G. Pinto, Rene D. R. Oliveira, Kalil A. Lima, Paula B. Donate, Jaqueline R. Silva, Bernard Ryffel, Thiago M. Cunha, José C. Alves-Filho, Foo Y. Liew, Paulo Louzada-Junior, Fernando de Queiroz Cunha
Pannus inflammation in sacroiliitis following immune pathological injury and radiological structural damage: a study of 193 patients with spondyloarthritis
Dan min Wang, Ling Lin, Jian hua Peng, Yao Gong, Zhi duo Hou, Su biao Chen, Zheng yu Xiao
Could low birth weight and preterm birth be associated with significant burden of hip osteoarthritis? A systematic review
Sultana Monira Hussain, Ilana N. Ackerman, Yuanyuan Wang, Ella Zomer, Flavia M. Cicuttini
Serum IL-33 level is associated with auto-antibodies but not with clinical response to biologic agents in rheumatoid arthritis
Elodie Rivière, Jérémie Sellam, Juliette Pascaud, Philippe Ravaud, Jacques-Eric Gottenberg, Xavier Mariette
Elevated levels of plasma symmetric dimethylarginine and increased arginase activity as potential indicators of cardiovascular comorbidity in rheumatoid arthritis
Unnikrishnan M. Chandrasekharan, Zeneng Wang, Yuping Wu, W. H. Wilson Tang, Stanley L. Hazen, Sihe Wang, M. Elaine Husni
GWAS-identified CCR1 and IL10 loci contribute to M1 macrophage-predominant inflammation in Behçet’s disease
Hiroto Nakano, Yohei Kirino, Mitsuhiro Takeno, Kana Higashitani, Hideto Nagai, Ryusuke Yoshimi, Yukie Yamaguchi, Ikuma Kato, Ichiro Aoki, Hideaki Nakajima
Correction to: Adiponectin aggravates bone erosion by promoting osteopontin production in synovial tissue of rheumatoid arthritis
Jie Qian, Lingxiao Xu, Xiaoxuan Sun, Yani Wang, Wenhua Xuan, Qian Zhang, Pengfei Zhao, Qin Wu, Rui Liu, Nan Che, Fang Wang, Wenfeng Tan, Miaojia Zhang
Anti-carbamylated protein antibodies as a new biomarker of erosive joint damage in systemic lupus erythematosus
Fulvia Ceccarelli, Carlo Perricone, Tania Colasanti, Laura Massaro, Enrica Cipriano, Monica Pendolino, Francesco Natalucci, Riccardo Mancini, Francesca Romana Spinelli, Guido Valesini, Fabrizio Conti, Cristiano Alessandri
Ten weeks of high-intensity interval walk training is associated with reduced disease activity and improved innate immune function in older adults with rheumatoid arthritis: a pilot study
David B. Bartlett, Leslie H. Willis, Cris A. Slentz, Andrew Hoselton, Leslie Kelly, Janet L. Huebner, Virginia B. Kraus, Jennifer Moss, Michael J. Muehlbauer, Guillaume Spielmann, William E. Kraus, Janet M. Lord, Kim M. Huffman
Is local platelet-rich plasma injection clinically superior to hyaluronic acid for treatment of knee osteoarthritis? A systematic review of randomized controlled trials
Di Yalong, Han Changxu, Zhao Liang, Ren Yizhong
Patient-reported outcomes from a randomized phase III trial of sarilumab monotherapy versus adalimumab monotherapy in patients with rheumatoid arthritis
Vibeke Strand, Laure Gossec, Clare W. J. Proudfoot, Chieh-I Chen, Matthew Reaney, Sophie Guillonneau, Toshio Kimura, Janet van Adelsberg, Yong Lin, Erin K. Mangan, Hubert van Hoogstraten, Gerd R. Burmester
Presence of hepatitis B virus in synovium and its clinical significance in rheumatoid arthritis
Yu-Lan Chen, Jun Jing, Ying-Qian Mo, Jian-Da Ma, Li-Juan Yang, Le-Feng Chen, Xiang Zhang, Tao Yan, Dong-Hui Zheng, Frank Pessler, Lie Dai
Glycation marker glucosepane increases with the progression of osteoarthritis and correlates with morphological and functional changes of cartilage in vivo
Catherine Legrand, Usman Ahmed, Attia Anwar, Kashif Rajpoot, Sabah Pasha, Cécile Lambert, Rose K. Davidson, Ian M. Clark, Paul J. Thornalley, Yves Henrotin, Naila Rabbani
Chemerin 156F, generated by chymase cleavage of prochemerin, is elevated in joint fluids of arthritis patients
Lei Zhao, Yasuto Yamaguchi, Xiaomei Ge, William H. Robinson, John Morser, Lawrence L. K. Leung
Hydroxychloroquine prescription trends and predictors for excess dosing per recent ophthalmology guidelines
April M. Jorge, Ronald B. Melles, Yuqing Zhang, Na Lu, Sharan K. Rai, Lucy H. Young, Karen H. Costenbader, Rosalind Ramsey-Goldman, S. Sam Lim, John M. Esdaile, Ann E. Clarke, M. B. Urowitz, Anca Askanase, Cynthia Aranow, Michelle Petri, Hyon Choi
The roles of neutrophil serine proteinases in idiopathic inflammatory myopathies
Siming Gao, Xiaoxia Zuo, Di Liu, Yizhi Xiao, Honglin Zhu, Huali Zhang, Hui Luo
Mediation analysis to understand genetic relationships between habitual coffee intake and gout
Joseph Hutton, Tahzeeb Fatima, Tanya J. Major, Ruth Topless, Lisa K. Stamp, Tony R. Merriman, Nicola Dalbeth
Obesity, hypertension and diuretic use as risk factors for incident gout: a systematic review and meta-analysis of cohort studies
Peter L. Evans, James A. Prior, John Belcher, Christian D. Mallen, Charles A. Hay, Edward Roddy
Next-generation sequencing profiling of mitochondrial genomes in gout
Chia-Chun Tseng, Chung-Jen Chen, Jeng-Hsien Yen, Hsi-Yuan Huang, Jan-Gowth Chang, Shun-Jen Chang, Wei-Ting Liao
Long noncoding RNA expression profile and association with SLEDAI score in monocyte-derived dendritic cells from patients with systematic lupus erythematosus
Yilun Wang, Shuang Chen, Sunyi Chen, Juan Du, Jinran Lin, Haihong Qin, Jie Wang, Jun Liang, Jinhua Xu
Methods for high-dimensional analysis of cells dissociated from cryopreserved synovial tissue
Laura T. Donlin, Deepak A. Rao, Kevin Wei, Kamil Slowikowski, Mandy J. McGeachy, Jason D. Turner, Nida Meednu, Fumitaka Mizoguchi, Maria Gutierrez-Arcelus, David J. Lieb, Joshua Keegan, Kaylin Muskat, Joshua Hillman, Cristina Rozo, Edd Ricker, Thomas M. Eisenhaure, Shuqiang Li, Edward P. Browne, Adam Chicoine, Danielle Sutherby, Akiko Noma, Jane Buckner, Derrick Todd, Michael Weisman, Ami Ben Artzi, Lindsy Forbess, Joan Bathon, John Carrino, Oganna Nwawka, Eric Matteson, Robert Darnell, Dana Orange, Rahul Satija, Diane Horowitz, Harris Perlman, Art Mandelin, Louis Bridges, Laura B. Hughes, Arnold Ceponis, Peter Lowry, Paul Emery, Ahmed Zayat, Amir Aslaam, Karen Salomon-Escoto, David Fox, Robert Ike, Andy Cordle, Aaron Wise, John Ashton, Javier Rangel-Moreno, Christopher Ritchlin, Darren Tabechian, Ralf Thiele, Deborah Parks, John Akinson, Chiam Putterman, Evan Der, Elena Massarotti, Michael Weisman, David Hildeman, Richard Furie, Betty Diamond, Michelle Petri, Diane Kamen, Melissa Cunningham, Jill Buyon, Iris Lee, Hasan Salameh, Maureen McMahon, Ken Kalunian, Maria Dall’Era, David Wofsy, Mattias Kretzler, Celine Berthier, William McCune, Ruba Kado, Wiliam Pendergraft, Dia Waguespack, Yanyan Liu, Gerald Watts, Arnon Arazi, Rohit Gupta, Holden Maecker, Patrick Dunn, Rong Mao, Mina Pichavant, Quan Chen, John Peyman, Ellen Goldmuntz, Justine Buschman, Jennifer Chi, Su-Yau Mao, Susana Serrate-Sztein, Yan Wang, Thomas Tuschl, Yvonne Lee, Chamith Fonseka, Fan Zhang, Ilya Korsunskiy, Judith A. James, Joel Guthridge, Chad Nusbaum, Stephen Kelly, Alessandra B. Pernis, Lionel B. Ivashkiv, Susan M. Goodman, William H. Robinson, Paul J. Utz, James A. Lederer, Ellen M. Gravallese, Brendan F. Boyce, Nir Hacohen, Costantino Pitzalis, Peter K. Gregersen, Gary S. Firestein, Soumya Raychaudhuri, Larry W. Moreland, V. Michael Holers, Vivian P. Bykerk, Andrew Filer, David L. Boyle, Michael B. Brenner, Jennifer H. Anolik
The prevalence of depression in axial spondyloarthritis and its association with disease activity: a systematic review and meta-analysis
Sizheng Zhao, Daniel Thong, Natasha Miller, Stephen J. Duffield, David M. Hughes, Laura Chadwick, Nicola J. Goodson
Radiographs in screening for sacroiliitis in children: what is the value?
Pamela F. Weiss, Rui Xiao, Timothy G. Brandon, David M. Biko, Walter P. Maksymowych, Robert G. Lambert, Jacob L. Jaremko, Nancy A. Chauvin
Extravascular manifestations of Takayasu arteritis: focusing on the features shared with spondyloarthritis
Oh Chan Kwon, Sang-Won Lee, Yong-Beom Park, Ji Seon Oh, Sang Hoon Lee, Seokchan Hong, Chang-Keun Lee, Bin Yoo, Yong-Gil Kim
Gout prevalence and predictors of urate-lowering therapy use: results from a population-based study
Huai Leng Pisaniello, Susan Lester, David Gonzalez-Chica, Nigel Stocks, Marie Longo, Greg R. Sharplin, Eleonora Dal Grande, Tiffany K. Gill, Samuel L. Whittle, Catherine L. Hill
miR-155 is dispensable in monosodium urate-induced gouty inflammation in mice
Qibin Yang, Quanbo Zhang, Yufeng Qing, Li Zhou, Qingsheng Mi, Jingguo Zhou
Adipocyte-specific Repression of PPAR-gamma by NCoR Contributes to Scleroderma Skin Fibrosis
Benjamin Korman, Roberta Goncalves Marangoni, Gabriel Lord, Jerrold Olefsky, Warren Tourtellotte, John Varga
The role of anti-citrullinated protein antibody reactivities in an inception cohort of patients with rheumatoid arthritis receiving treat-to-target therapy
Maria Karolina Jonsson, Aase Haj Hensvold, Monika Hansson, Anna-Birgitte Aga, Joseph Sexton, Linda Mathsson-Alm, Martin Cornillet, Guy Serre, Siri Lillegraven, Bjørg-Tilde Svanes Fevang, Anca Irinel Catrina, Espen Andre Haavardsholm
Prediction of primary non-response to methotrexate therapy using demographic, clinical and psychosocial variables: results from the UK Rheumatoid Arthritis Medication Study (RAMS)
Jamie C. Sergeant, Kimme L. Hyrich, James Anderson, Kamilla Kopec-Harding, Holly F. Hope, Deborah P. M. Symmons, Adebajo Ade, Ahmed Khalid, Al-Ansari Atheer, Amarasena Roshan, Bukhari Marwan, Callan Margaret, G. Chelliah Easwaradhas, Chinoy Hector, Cooper Annie, Dasgupta Bhaskar, Davis Martin, Galloway James, Gough Andrew, Green Michael, Gullick Nicola, Hamilton Jennifer, Hassan Waji, Hider Samantha, Hyrich Kimme, Kamath Sanjeet, Knight Susan, Lane Suzanne, Lee Martin, Levy Sarah, Macphie Lizzy, Marguerie Christopher, Marshall Tarnya, Mathews Catherine, Mc Kenna Frank, Naz Sophia, Perry Mark, Pollard Louise, Quilty Brian, Robertson Lindsay, Roy Dipak, Sanders Paul, Saravanan Vadivelu, Scott David, Smith Gillian, Smith Richard, Symmons Deborah, Teh Lee-Suan, Viner Nick, Anne Barton, Suzanne M. M. Verstappen
Control of cytokine mRNA degradation by the histone deacetylase inhibitor ITF2357 in rheumatoid arthritis fibroblast-like synoviocytes: beyond transcriptional regulation
Chiara Angiolilli, Pawel A. Kabala, Aleksander M. Grabiec, Marzia Rossato, Wi S. Lai, Gianluca Fossati, Paolo Mascagni, Christian Steinkühler, Perry J. Blackshear, Kris A. Reedquist, Dominique L. Baeten, Timothy R. D. J. Radstake
Functional intraepithelial lymphocyte changes in inflammatory bowel disease and spondyloarthritis have disease specific correlations with intestinal microbiota
Emilie H. Regner, Neha Ohri, Andrew Stahly, Mark E. Gerich, Blair P. Fennimore, Diana Ir, Widian K. Jubair, Carsten Görg, Janet Siebert, Charles E. Robertson, Liron Caplan, Daniel N. Frank, Kristine A. Kuhn
Sex-based differences in association between circulating T cell subsets and disease activity in untreated early rheumatoid arthritis patients
Jonathan Aldridge, Jayesh M. Pandya, Linda Meurs, Kerstin Andersson, Inger Nordström, Elke Theander, Anna-Carin Lundell, Anna Rudin
Effect of subcutaneous tocilizumab treatment on work/housework status in biologic-naïve rheumatoid arthritis patients using inverse probability of treatment weighting: FIRST ACT-SC study
Yoshiya Tanaka, Hideto Kameda, Kazuyoshi Saito, Yuko Kaneko, Eiichi Tanaka, Shinsuke Yasuda, Naoto Tamura, Keishi Fujio, Takao Fujii, Toshihisa Kojima, Tatsuhiko Anzai, Chikuma Hamada, Yoshihisa Fujino, Shinya Matsuda, Hitoshi Kohsaka
The plasma biomarker soluble SIGLEC-1 is associated with the type I interferon transcriptional signature, ethnic background and renal disease in systemic lupus erythematosus
João J. Oliveira, Sarah Karrar, Daniel B. Rainbow, Christopher L. Pinder, Pamela Clarke, Arcadio Rubio García, Osama Al-Assar, Keith Burling, Sian Morris, Richard Stratton, Tim J. Vyse, Linda S. Wicker, John A. Todd, Ricardo C. Ferreira
Resolution of synovitis and arrest of catabolic and anabolic bone changes in patients with psoriatic arthritis by IL-17A blockade with secukinumab: results from the prospective PSARTROS study
Eleni Kampylafka, Isabelle d’Oliveira, Christina Linz, Veronika Lerchen, Fabian Stemmler, David Simon, Matthias Englbrecht, Michael Sticherling, Jürgen Rech, Arnd Kleyer, Georg Schett, Axel J. Hueber
A bivalent compound targeting CCR5 and the mu opioid receptor treats inflammatory arthritis pain in mice without inducing pharmacologic tolerance
Raini Dutta, Mary M. Lunzer, Jennifer L. Auger, Eyup Akgün, Philip S. Portoghese, Bryce A. Binstadt
A randomized controlled trial comparing PF-06438179/GP1111 (an infliximab biosimilar) and infliximab reference product for treatment of moderate to severe active rheumatoid arthritis despite methotrexate therapy
Stanley B. Cohen, Rieke Alten, Hideto Kameda, Tomas Hala, Sebastiao C. Radominski, Muhammad I. Rehman, Ramesh Palaparthy, Karl Schumacher, Susanne Schmitt, Steven Y. Hua, Claudia Ianos, K. Lea Sewell
Widespread pain in axial spondyloarthritis: clinical importance and gender differences
Thijs Willem Swinnen, René Westhovens, Wim Dankaerts, Kurt de Vlam
Effects of CTLA4-Ig treatment on circulating fibrocytes and skin fibroblasts from the same systemic sclerosis patients: an in vitro assay
Maurizio Cutolo, Stefano Soldano, Paola Montagna, Amelia Chiara Trombetta, Paola Contini, Barbara Ruaro, Alberto Sulli, Stefano Scabini, Emanuela Stratta, Sabrina Paolino, Carmen Pizzorni, Vanessa Smith, Renata Brizzolara
Serum levels of B-cell activating factor of the TNF family (BAFF) correlate with anti-Jo-1 autoantibodies levels and disease activity in patients with anti-Jo-1positive polymyositis and dermatomyositis
Olga Kryštůfková, Hana Hulejová, Heřman F. Mann, Ondřej Pecha, Ivana Půtová, Louise Ekholm, Ingrid E. Lundberg, Jiří Vencovský
ADAM-17 is expressed on rheumatoid arthritis fibroblast-like synoviocytes and regulates proinflammatory mediator expression and monocyte adhesion
Sho Ishii, Takeo Isozaki, Hidekazu Furuya, Hiroko Takeuchi, Yumi Tsubokura, Katsunori Inagaki, Tsuyoshi Kasama
Ten years of follow-up data in psoriatic arthritis: results based on standardized monitoring of patients in an ordinary outpatient clinic in southern Norway
Glenn Haugeberg, Brigitte Michelsen, Stig Tengesdal, Inger Johanne Widding Hansen, Andreas Diamantopoulos, Arthur Kavanaugh
BATF regulates collagen-induced arthritis by regulating T helper cell differentiation
Sang-Heon Park, Jinseol Rhee, Seul-Ki Kim, Jung-Ah Kang, Ji-Sun Kwak, Young-Ok Son, Wan-Su Choi, Sung-Gyoo Park, Jang-Soo Chun
A five-year prospective study of spinal radiographic progression and its predictors in men and women with ankylosing spondylitis
Anna Deminger, Eva Klingberg, Mats Geijer, Jan Göthlin, Martin Hedberg, Eva Rehnberg, Hans Carlsten, Lennart T. Jacobsson, Helena Forsblad-d’Elia
GPR120 is an important inflammatory regulator in the development of osteoarthritis
Yuanfeng Chen, Dan Zhang, Ki Wai Ho, Sien Lin, Wade Chun-Wai Suen, Huantian Zhang, Zhengang Zha, Gang Li, Po Sing Leung
Serum metabolomic profiling predicts synovial gene expression in rheumatoid arthritis
Rekha Narasimhan, Roxana Coras, Sara B. Rosenthal, Shannon R. Sweeney, Alessia Lodi, Stefano Tiziani, David Boyle, Arthur Kavanaugh, Monica Guma
Factors associated with the achievement of biological disease-modifying antirheumatic drug-free remission in rheumatoid arthritis: the ANSWER cohort study
Motomu Hashimoto, Moritoshi Furu, Wararu Yamamoto, Takanori Fujimura, Ryota Hara, Masaki Katayama, Akira Ohnishi, Kengo Akashi, Shuzo Yoshida, Koji Nagai, Yonsu Son, Hideki Amuro, Toru Hirano, Kosuke Ebina, Ryuji Uozumi, Hiromu Ito, Masao Tanaka, Koichiro Ohmura, Takao Fujii, Tsuneyo Mimori
Do ethnicity, degree of family relationship, and the spondyloarthritis subtype in affected relatives influence the association between a positive family history for spondyloarthritis and HLA-B27 carriership? Results from the worldwide ASAS cohort
Miranda van Lunteren, Alexandre Sepriano, Robert Landewé, Joachim Sieper, Martin Rudwaleit, Désirée van der Heijde, Floris van Gaalen
Comparative effectiveness of allopurinol versus febuxostat for preventing incident dementia in older adults: a propensity-matched analysis
Jasvinder A. Singh, John D. Cleveland
Expansion and activation of monocytic-myeloid-derived suppressor cell via STAT3/arginase-I signaling in patients with ankylosing spondylitis
Yu-feng Liu, Kun-hai Zhuang, Bin Chen, Pei-wu Li, Xuan Zhou, Hua Jiang, Li-mei Zhong, Feng-bin Liu
NLRP3 inflammasome inhibitor OLT1177 suppresses joint inflammation in murine models of acute arthritis
Carlo Marchetti, Benjamin Swartzwelter, Marije I. Koenders, Tania Azam, Isak W. Tengesdal, Nick Powers, Dennis M. de Graaf, Charles A. Dinarello, Leo A. B. Joosten
Role of the mTOR pathway in minor salivary gland changes in Sjogren’s syndrome and systemic sclerosis
Zeki Soypaçacı, Zeynep Zehra Gümüş, Fulya Çakaloğlu, Mustafa Özmen, Dilek Solmaz, Sercan Gücenmez, Önay Gercik, Servet Akar
Biologics and cardiovascular events in inflammatory arthritis: a prospective national cohort study
Joshua L. Lee, Premarani Sinnathurai, Rachelle Buchbinder, Catherine Hill, Marissa Lassere, Lyn March
Impact of oral osteoarthritis therapy usage among other risk factors on knee replacement: a nested case-control study using the Osteoarthritis Initiative cohort
Marc Dorais, Johanne Martel-Pelletier, Jean-Pierre Raynauld, Philippe Delorme, Jean-Pierre Pelletier
Cytokine profiling in active and quiescent SLE reveals distinct patient subpopulations
John A. Reynolds, Eoghan M. McCarthy, Sahena Haque, Pintip Ngamjanyaporn, Jamie C. Sergeant, Elaine Lee, Eileen Lee, Stephen A. Kilfeather, Ben Parker, Ian N. Bruce
Induction of sustained remission in early inflammatory arthritis with the combination of infliximab plus methotrexate: the DINORA trial
Tanja Alexandra Stamm, Klaus Peter Machold, Daniel Aletaha, Farideh Alasti, Peter Lipsky, David Pisetsky, Robert Landewe, Desiree van der Heijde, Alexandre Sepriano, Martin Aringer, Dimitri Boumpas, Gerd Burmester, Maurizio Cutolo, Wolfgang Ebner, Winfried Graninger, Tom Huizinga, Georg Schett, Hendrik Schulze-Koops, Paul-Peter Tak, Emilio Martin-Mola, Ferdinand Breedveld, Josef Smolen
Mediterranean diet and risk of rheumatoid arthritis: a population-based case-control study
Kari Johansson, Johan Askling, Lars Alfredsson, Daniela Di Giuseppe
Investigation of myositis and scleroderma specific autoantibodies in patients with lung cancer
Zoe E. Betteridge, Lynsey Priest, Robert G. Cooper, Neil J. McHugh, Fiona Blackhall, Janine A. Lamb
Correction to: miR-155 is dispensable in monosodium urate-induced gouty inflammation in mice
Qibin Yang, Quanbo Zhang, Yufeng Qing, Li Zhou, Qingsheng Mi, Jingguo Zhou
A comparative clinical study of PF-06410293, a candidate adalimumab biosimilar, and adalimumab reference product (Humira®) in the treatment of active rheumatoid arthritis
Roy M. Fleischmann, Rieke Alten, Margarita Pileckyte, Kasia Lobello, Steven Y. Hua, Carol Cronenberger, Daniel Alvarez, Amy E. Bock, K. Lea Sewell
The relationship between ferritin and urate levels and risk of gout
Tahzeeb Fatima, Cushla McKinney, Tanya J. Major, Lisa K. Stamp, Nicola Dalbeth, Cory Iverson, Tony R. Merriman, Jeffrey N. Miner
Clinical signs and symptoms in a joint model of four disease activity parameters in juvenile dermatomyositis: a prospective, longitudinal, multicenter cohort study
E. H. Pieter van Dijkhuizen, Maria De Iorio, Lucy R. Wedderburn, Claire T. Deakin, Kate Armon, Joe Ellis-Gage, Holly Roper, Vanja Briggs, Joanna Watts, Liza McCann, Ian Roberts, Eileen Baildam, Louise Hanna, Olivia Lloyd, Susan Wadeson, Phil Riley, Ann McGovern, Clive Ryder, Janis Scott, Beverley Thomas, Taunton Southwood, Eslam Al-Abadi, Sue Wyatt, Gillian Jackson, Tania Amin, Mark Wood, Vanessa VanRooyen, Deborah Burton, Joyce Davidson, Janet Gardner-Medwin, Neil Martin, Sue Ferguson, Liz Waxman, Michael Browne, Mark Friswell, Helen Foster, Alison Swift, Sharmila Jandial, Vicky Stevenson, Debbie Wade, Ethan Sen, Eve Smith, Lisa Qiao, Stuart Watson, Claire Duong, Helen Venning, Rangaraj Satyapal, Elizabeth Stretton, Mary Jordan, Ellen Mosley, Anna Frost, Lindsay Crate, Kishore Warrier, Stefanie Stafford, Lucy Wedderburn, Clarissa Pilkington, Nathan Hasson, Sue Maillard, Elizabeth Halkon, Virginia Brown, Audrey Juggins, Sally Smith, Sian Lunt, Elli Enayat, Hemlata Varsani, Laura Kassoumeri, Laura Beard, Katie Arnold, Yvonne Glackin, Stephanie Simou, Beverley Almeida, Kiran Nistala, Raquel Marques, Claire Deakin, Stefanie Dowle, Charalampia Papadopoulou, Shireena Yasin, Cerise Johnson-Moore, Emily Robinson, Kevin Murray, John Ioannou, Linda Suffield, Muthana Al-Obaidi, Helen Lee, Sam Leach, Helen Smith, Anne-Marie McMahon, Heather Chisem, Ruth Kingshott, Nick Wilkinson, Emma Inness, Eunice Kendall, David Mayers, Ruth Etherton, Danielle Miller, Kathryn Bailey, Jacqui Clinch, Natalie Fineman, Helen Pluess-Hall, Lindsay Vallance, Louise Akeroyd, Alice Leahy, Amy Collier, Rebecca Cutts, Emma Macleod, Hans De Graaf, Brian Davidson, Sarah Hartfree, Danny Pratt
High-frequency ultrasound of the skin in systemic sclerosis: an exploratory study to examine correlation with disease activity and to define the minimally detectable difference
Hongyan Li, Daniel E. Furst, Hongtao Jin, Chao Sun, Xiaoping Wang, Lin Yang, Jingjing He, Yanru Wang, Aijing Liu
Aberrantly expressed messenger RNAs and long noncoding RNAs in degenerative nucleus pulposus cells co-cultured with adipose-derived mesenchymal stem cells
Zhihua Han, Jiandong Wang, Liang Gao, Qiugen Wang, Jianhong Wu
Evaluation of 99mTc-rhAnnexin V-128 SPECT/CT as a diagnostic tool for early stages of interstitial lung disease associated with systemic sclerosis
Janine Schniering, Li Guo, Matthias Brunner, Roger Schibli, Shuang Ye, Oliver Distler, Martin Béhé, Britta Maurer
Effects of transitional care on self-care, readmission rates, and quality of life in adult patients with systemic lupus erythematosus: a randomized controlled trial
Xia Xie, Yuqing Song, Hui Yang, Anliu Nie, Hong Chen, Ji-ping Li
Serum biomarker for diagnostic evaluation of pulmonary arterial hypertension in systemic sclerosis
Lisa M. Rice, Julio C. Mantero, Eric A. Stratton, Rod Warburton, Kari Roberts, Nicholas Hill, Robert W. Simms, Robyn Domsic, Harrison W. Farber, Robert Layfatis
Loss of Gαq impairs regulatory B-cell function
Yan He, Xiaoqing Yuan, Yan Li, Chunlian Zhong, Yuan Liu, Hongyan Qian, Jingxiu Xuan, Lihua Duan, Guixiu Shi
Immune complexes containing scleroderma-specific autoantibodies induce a profibrotic and proinflammatory phenotype in skin fibroblasts
Elena Raschi, Cecilia Beatrice Chighizola, Laura Cesana, Daniela Privitera, Francesca Ingegnoli, Claudio Mastaglio, Pier Luigi Meroni, Maria Orietta Borghi
T-cell transcriptomics from peripheral blood highlights differences between polymyositis and dermatomyositis patients
Miranda Houtman, Louise Ekholm, Espen Hesselberg, Karine Chemin, Vivianne Malmström, Ann M. Reed, Ingrid E. Lundberg, Leonid Padyukov
Osteogenic differentiation of fibroblast-like synovial cells in rheumatoid arthritis is induced by microRNA-218 through a ROBO/Slit pathway
Naoki Iwamoto, Shoichi Fukui, Ayuko Takatani, Toshimasa Shimizu, Masataka Umeda, Ayako Nishino, Takashi Igawa, Tomohiro Koga, Shin-ya Kawashiri, Kunihiro Ichinose, Mami Tmai, Hideki Nakamura, Tomoki Origuchi, Ko Chiba, Makoto Osaki, Astrid Jüngel, Steffen Gay, Atsushi Kawakami
The risk of clinically diagnosed gout by serum urate levels: results from 30 years follow-up of the Malmö Preventive Project cohort in southern Sweden
Meliha C. Kapetanovic, Peter Nilsson, Carl Turesson, Martin Englund, Nicola Dalbeth, Lennart Jacobsson
An explorative study on deep profiling of peripheral leukocytes to identify predictors for responsiveness to anti-tumour necrosis factor alpha therapies in ankylosing spondylitis: natural killer cells in focus
Ursula Schulte-Wrede, Till Sörensen, Joachim R. Grün, Thomas Häupl, Heike Hirseland, Marta Steinbrich-Zöllner, Peihua Wu, Andreas Radbruch, Denis Poddubnyy, Joachim Sieper, Uta Syrbe, Andreas Grützkau
Recombinant human proteoglycan-4 reduces phagocytosis of urate crystals and downstream nuclear factor kappa B and inflammasome activation and production of cytokines and chemokines in human and murine macrophages
Marwa Qadri, Gregory D. Jay, Ling X. Zhang, Wendy Wong, Anthony M. Reginato, Changqi Sun, Tannin A. Schmidt, Khaled A. Elsaid
Interferon-λ3/4 genetic variants and interferon-λ3 serum levels are biomarkers of lupus nephritis and disease activity in Taiwanese
Ji-Yih Chen, Chin-Man Wang, Tai-Di Chen, Yeong-Jian Jan Wu, Jing-Chi Lin, Ling Ying Lu, Jianming Wu
The host cellular immune response to cytomegalovirus targets the endothelium and is associated with increased arterial stiffness in ANCA-associated vasculitis
Dimitrios Chanouzas, Michael Sagmeister, Lovesh Dyall, Phoebe Sharp, Lucy Powley, Serena Johal, Jessica Bowen, Peter Nightingale, Charles J. Ferro, Matthew D. Morgan, Paul Moss, Lorraine Harper
Detection of high cardiovascular risk patients with ankylosing spondylitis based on the assessment of abdominal aortic calcium as compared to carotid ultrasound
Javier Rueda-Gotor, Fernanda Genre, Alfonso Corrales, Ricardo Blanco, Patricia Fuentevilla, Virginia Portilla, Rosa Expósito, Cristina Mata, Trinitario Pina, Carlos González-Juanatey, Luis Rodriguez-Rodriguez, Miguel A. González-Gay
Tofacitinib inhibits granulocyte–macrophage colony-stimulating factor-induced NLRP3 inflammasome activation in human neutrophils
Makiko Yashiro Furuya, Tomoyuki Asano, Yuya Sumichika, Shuzo Sato, Hiroko Kobayashi, Hiroshi Watanabe, Eiji Suzuki, Hideko Kozuru, Hiroshi Yatsuhashi, Tomohiro Koga, Hiromasa Ohira, Hideharu Sekine, Atsushi Kawakami, Kiyoshi Migita
T-cell costimulation blockade is effective in experimental digestive and lung tissue fibrosis
Gonçalo Boleto, Christophe Guignabert, Sonia Pezet, Anne Cauvet, Jérémy Sadoine, Ly Tu, Carole Nicco, Camille Gobeaux, Frédéric Batteux, Yannick Allanore, Jérôme Avouac
Comments on the article “Effectiveness and safety of tofacitinib in rheumatoid arthritis: a cohort study”
Thuy Nhu Thai, Ghadeer K. Dawwas
Physical activity is related to function and fatigue but not pain in women with fibromyalgia: baseline analyses from the Fibromyalgia Activity Study with TENS (FAST)
Ericka N. Merriwether, Laura A. Frey-Law, Barbara A. Rakel, Miriam B. Zimmerman, Dana L. Dailey, Carol G. T. Vance, Meenakshi Golchha, Katherine M. Geasland, Ruth Chimenti, Leslie J. Crofford, Kathleen A. Sluka
Enhanced IL-6/phosphorylated STAT3 signaling is related to the imbalance of circulating T follicular helper/T follicular regulatory cells in patients with rheumatoid arthritis
Qian Niu, Zhuo-chun Huang, Xiao-juan Wu, Ya-xiong Jin, Yun-fei An, Ya-mei Li, Huan Xu, Bin Yang, Lan-lan Wang
Short Link N promotes disc repair in a rabbit model of disc degeneration
Fackson Mwale, Koichi Masuda, Michael P. Grant, Laura M. Epure, Kenji Kato, Shingo Miyazaki, Kevin Cheng, Junichi Yamada, Won C. Bae, Carol Muehleman, Peter J. Roughley, John Antoniou
Cortical bone loss is an early feature of nonradiographic axial spondyloarthritis
Anna Neumann, Judith Haschka, Arnd Kleyer, Louis Schuster, Matthias Englbrecht, Andreas Berlin, Camille P. Figueiredo, David Simon, Christian Muschitz, Roland Kocijan, Heinrich Resch, Jürgen Rech, Georg Schett
Simultaneous quantification of bone erosions and enthesiophytes in the joints of patients with psoriasis or psoriatic arthritis - effects of age and disease duration
David Simon, Arnd Kleyer, Francesca Faustini, Matthias Englbrecht, Judith Haschka, Andreas Berlin, Sebastian Kraus, Axel J. Hueber, Roland Kocijan, Michael Sticherling, Juergen Rech, Georg Schett
Arhalofenate acid inhibits monosodium urate crystal-induced inflammatory responses through activation of AMP-activated protein kinase (AMPK) signaling
Charles McWherter, Yun-Jung Choi, Ramon L. Serrano, Sushil K. Mahata, Robert Terkeltaub, Ru Liu-Bryan
The role of RORα in salivary gland lesions in patients with primary Sjögren’s syndrome
Xiuhong Weng, Yi Liu, Shun Cui, Bo Cheng
Correction to: Comorbidity in gout at the time of first diagnosis: sex differences that may have implications for dosing of urate lowering therapy
Panagiota Drivelegka, Valgerdur Sigurdardottir, Anna Svärd, Lennart T. H. Jacobsson, Mats Dehlin
Osteoporosis of the vertebra and osteochondral remodeling of the endplate causes intervertebral disc degeneration in ovariectomized mice
Zhi-feng Xiao, Jian-bo He, Guo-yi Su, Mei-hui Chen, Yu Hou, Shu-dong Chen, Ding-kun Lin
Monosodium urate crystals reduce osteocyte viability and indirectly promote a shift in osteocyte function towards a proinflammatory and proresorptive state
Ashika Chhana, Bregina Pool, Karen E. Callon, Mei Lin Tay, David Musson, Dorit Naot, Geraldine McCarthy, Susan McGlashan, Jillian Cornish, Nicola Dalbeth
A single determination of C-reactive protein does not suffice to declare a patient with a diagnosis of axial spondyloarthritis ‘CRP-negative’
Robert Landewé, Tommi Nurminen, Owen Davies, Dominique Baeten
Monosodium urate burden assessed with dual-energy computed tomography predicts the risk of flares in gout: a 12-month observational study
Tristan Pascart, Agathe Grandjean, Benoist Capon, Julie Legrand, Nasser Namane, Vincent Ducoulombier, Marguerite Motte, Marie Vandecandelaere, Hélène Luraschi, Catherine Godart, Eric Houvenagel, Laurène Norberciak, Jean-François Budzik
Effects of a 15-month anti-TNF-α treatment on plasma levels of glycosaminoglycans in women with rheumatoid arthritis
Anna Szeremeta, Agnieszka Jura-Półtorak, Ewa Maria Koźma, Andrzej Głowacki, Eugeniusz Józef Kucharz, Magdalena Kopeć-Mędrek, Krystyna Olczyk
1,25(OH)2D3 and dexamethasone additively suppress synovial fibroblast activation by CCR6+ T helper memory cells and enhance the effect of tumor necrosis factor alpha blockade
Wendy Dankers, Claudia González-Leal, Nadine Davelaar, Patrick S. Asmawidjaja, Adriana M. C. Mus, Johanna M. W. Hazes, Edgar M. Colin, Erik Lubberts
Interaction between CD177 and platelet endothelial cell adhesion molecule-1 downregulates membrane-bound proteinase-3 (PR3) expression on neutrophils and attenuates neutrophil activation induced by PR3-ANCA
Hui Deng, Nan Hu, Chen Wang, Min Chen, Ming-Hui Zhao
Metabolomic alterations associated with Behçet’s disease
Wenjie Zheng, Xiuhua Wu, Maryam Goudarzi, Jing Shi, Wei Song, Chaoran Li, Jinjing Liu, Hua Chen, Xuan Zhang, Xiaofeng Zeng, Heng-Hong Li
Neuropathic-like knee pain and associated risk factors: a cross-sectional study in a UK community sample
Gwen Sascha Fernandes, Ana Marie Valdes, David Andrew Walsh, Weiya Zhang, Michael Doherty
From association to mechanism in complex disease genetics: the role of the 3D genome
Yao Fu, Kandice L Tessneer, Chuang Li, Patrick M Gaffney
CCN family member 2/connective tissue growth factor (CCN2/CTGF) is regulated by Wnt–β-catenin signaling in nucleus pulposus cells
Akihiko Hiyama, Kosuke Morita, Daisuke Sakai, Masahiko Watanabe
Are gender-specific approaches needed in diagnosing early axial spondyloarthritis? Data from the SPondyloArthritis Caught Early cohort
Augusta Ortolan, Miranda van Lunteren, Sofia Ramiro, Roberta Ramonda, Robert B. M. Landewé, Hanne Dagfinrud, Lennart T. H. Jacobsson, Désirée van der Heijde, Floris A. van Gaalen
CYLD suppression enhances the pro-inflammatory effects and hyperproliferation of rheumatoid arthritis fibroblast-like synoviocytes by enhancing NF-κB activation
Le-meng Zhang, Jing-Jing Zhou, Chun-lei Luo
Association between brain-derived neurotrophic factor gene polymorphisms and fibromyalgia in a Korean population: a multicenter study
Dong-Jin Park, Seong-Ho Kim, Seong-Su Nah, Ji Hyun Lee, Seong-Kyu Kim, Yeon-Ah Lee, Seung-Jae Hong, Hyun-Sook Kim, Hye-Soon Lee, Hyoun Ah Kim, Chung-Il Joung, Sang-Hyon Kim, Shin-Seok Lee
Influence of HLA-B27 on the Ankylosing Spondylitis phenotype: results from the REGISPONSER database
Marta Arévalo, Jordi Gratacós Masmitjà, Mireia Moreno, Joan Calvet, Cristobal Orellana, Desirée Ruiz, Carmen Castro, Pilar Carreto, Marta Larrosa, Eduardo Collantes, Pilar Font
Increase of circulating memory B cells after glucocorticoid-induced remission identifies patients at risk of IgG4-related disease relapse
Marco Lanzillotta, Emanuel Della-Torre, Raffaella Milani, Enrica Bozzolo, Emanuele Bozzalla-Cassione, Lucrezia Rovati, Paolo Giorgio Arcidiacono, Stefano Partelli, Massimo Falconi, Fabio Ciceri, Lorenzo Dagna
Blocking CD248 molecules in perivascular stromal cells of patients with systemic sclerosis strongly inhibits their differentiation toward myofibroblasts and proliferation: a new potential target for antifibrotic therapy
Paola Di Benedetto, Vasiliki Liakouli, Piero Ruscitti, Onorina Berardicurti, Francesco Carubbi, Noemi Panzera, Salvatore Di Bartolomeo, Giuliana Guggino, Francesco Ciccia, Giovanni Triolo, Paola Cipriani, Roberto Giacomelli
Is synovial hypertrophy without Doppler activity sensitive to change? Post-hoc analysis from a rheumatoid arthritis ultrasound study
Lene Terslev, Mikkel Østergaard, Joe Sexton, Hilde Berner Hammer
E2F2 directly regulates the STAT1 and PI3K/AKT/NF-κB pathways to exacerbate the inflammatory phenotype in rheumatoid arthritis synovial fibroblasts and mouse embryonic fibroblasts
Shiguan Wang, Lin Wang, Changshun Wu, Shui Sun, Ji-hong Pan
The frequency of ANCA-associated vasculitis in a national database of hospitalized patients in China
Jiannan Li, Zhao Cui, Jian-yan Long, Wei Huang, Jin-wei Wang, Haibo Wang, Luxia Zhang, Min Chen, Ming-hui Zhao
Persistence and adverse events of biological treatment in adult patients with juvenile idiopathic arthritis: results from BIOBADASER
Juan José Bethencourt Baute, Carlos Sanchez-Piedra, Dolores Ruiz-Montesinos, Marta Medrano San Ildefonso, Carlos Rodriguez-Lozano, Eva Perez-Pampin, Ana Ortiz, Sara Manrique, Rosa Roselló, Victoria Hernandez, Cristina Campos, Agustí Sellas, Walter Alberto Sifuentes-Giraldo, Javier García-González, Fernando Sanchez-Alonso, Federico Díaz-González, Juan Jesús Gómez-Reino, Sagrario Bustabad Reyes
What is the value of musculoskeletal ultrasound in patients presenting with arthralgia to predict inflammatory arthritis development? A systematic literature review
Rosaline van den Berg, Sarah Ohrndorf, Marion C. Kortekaas, Annette H. M. van der Helm-van Mil
Modulation of T-cell responses by anti-tumor necrosis factor treatments in rheumatoid arthritis: a review
Jean-Luc Davignon, Benjamin Rauwel, Yannick Degboé, Arnaud Constantin, Jean-Fredéric Boyer, Andrey Kruglov, Alain Cantagrel
Baseline metabolic profiles of early rheumatoid arthritis patients achieving sustained drug-free remission after initiating treat-to-target tocilizumab, methotrexate, or the combination: insights from systems biology
Xavier M Teitsma, Wei Yang, Johannes W G Jacobs, Attila Pethö-Schramm, Michelle E A Borm, Amy C Harms, Thomas Hankemeier, Jacob M van Laar, Johannes W J Bijlsma, Floris P J G Lafeber
Low bone mineral density predicts the formation of new syndesmophytes in patients with axial spondyloarthritis
Hyoung Rae Kim, Yeon Sik Hong, Sung-Hwan Park, Ji Hyeon Ju, Kwi Young Kang
Obesity alters the in vivo mechanical response and biochemical properties of cartilage as measured by MRI
Amber T Collins, Micaela L Kulvaranon, Hattie C Cutcliffe, Gangadhar M Utturkar, Wyatt A R Smith, Charles E Spritzer, Farshid Guilak, Louis E DeFrate
Is the exposure to bisphosphonates or osteoporosis the predictor of spinal radiographic progression in ankylosing spondylitis?
Giovanni Orsolini, Giovanni Adami, Maurizio Rossini, Angelo Fassio, Alessandro Giollo, Cristian Caimmi, Luca Idolazzi, Davide Gatti, Ombretta Viapiana
I do not want to suppress the natural process of inflammation: new insights on factors associated with non-adherence in rheumatoid arthritis
Valentin Ritschl, Angelika Lackner, Carina Boström, Erika Mosor, Michaela Lehner, Maisa Omara, Romualdo Ramos, Paul Studenic, Josef Sebastian Smolen, Tanja Alexandra Stamm
Prognostic profile of systemic sclerosis: analysis of the clinical EUSTAR cohort in China
Shasha Hu, Yong Hou, Qian Wang, Mengtao Li, Dong Xu, Xiaofeng Zeng
Downregulation of miRNA17–92 cluster marks Vγ9Vδ2 T cells from patients with rheumatoid arthritis
Giuliana Guggino, Valentina Orlando, Laura Saieva, Piero Ruscitti, Paola Cipriani, Marco Pio La Manna, Roberto Giacomelli, Riccardo Alessandro, Giovanni Triolo, Francesco Ciccia, Francesco Dieli, Nadia Caccamo
MRI-detected osteophytes of the knee: natural history and structural correlates of change
Zhaohua Zhu, Changhai Ding, Weiyu Han, Shuang Zheng, Tania Winzenberg, Flavia Cicuttini, Graeme Jones
Cytokine production by activated plasmacytoid dendritic cells and natural killer cells is suppressed by an IRAK4 inhibitor
Karin Hjorton, Niklas Hagberg, Elisabeth Israelsson, Lisa Jinton, Olof Berggren, Johanna K. Sandling, Kristofer Thörn, John Mo, Maija-Leena Eloranta, Lars Rönnblom
Prospective evaluation of the capillaroscopic skin ulcer risk index in systemic sclerosis patients in clinical practice: a longitudinal, multicentre study
Ulrich A. Walker, Veronika K. Jaeger, Katharina M. Bruppacher, Rucsandra Dobrota, Lionel Arlettaz, Martin Banyai, Jörg Beron, Carlo Chizzolini, Ernst Groechenig, Rüdiger B. Mueller, François Spertini, Peter M. Villiger, Oliver Distler
Relevance of interferon-gamma in pathogenesis of life-threatening rapidly progressive interstitial lung disease in patients with dermatomyositis
Yuichi Ishikawa, Shigeru Iwata, Kentaro Hanami, Aya Nawata, Mingzeng Zhang, Kaoru Yamagata, Shintaro Hirata, Kei Sakata, Yasuyuki Todoroki, Kazuhisa Nakano, Shingo Nakayamada, Minoru Satoh, Yoshiya Tanaka
Should our approach to diuretic using in patients with gout change?
Duygu Tecer, Gozde Kubra Yardımcı, Alper Sari, Hakan Babaoglu
Disease-specific composite measures for psoriatic arthritis are highly responsive to a Janus kinase inhibitor treatment that targets multiple domains of disease
Philip Helliwell, Laura C. Coates, Oliver FitzGerald, Peter Nash, Enrique R. Soriano, M. Elaine Husni, Ming-Ann Hsu, Keith S. Kanik, Thijs Hendrikx, Joseph Wu, Elizabeth Kudlacz
Risk of chronic kidney disease in patients with gout and the impact of urate lowering therapy: a population-based cohort study
Matthew Roughley, Alyshah Abdul Sultan, Lorna Clarson, Sara Muller, Rebecca Whittle, John Belcher, Christian D. Mallen, Edward Roddy
Psychometric validation of an empowerment scale for Spanish-speaking patients with rheumatoid arthritis
Irazú Contreras-Yáñez, Emmanuel Ruiz-Medrano, Luz del Carmen R. Hernández, Virginia Pascual-Ramos
Potential therapeutic antibodies targeting specific adiponectin isoforms in rheumatoid arthritis
Yeon-Ah Lee, Dae-Hyun Hahm, Jung Yeon Kim, Bonjun Sur, Hyun Min Lee, Chun Jeih Ryu, Hyung-In Yang, Kyoung Soo Kim
Changes in hepatitis B virus surface antibody titer and risk of hepatitis B reactivation in HBsAg-negative/HBcAb-positive patients undergoing biologic therapy for rheumatic diseases: a prospective cohort study
Ya-Chih Tien, Hsu-Heng Yen, Ching-Fang Li, Mei-Ping Liu, Yin-Tzu Hsue, Ming-Hui Hung, Ying-Ming Chiu
The involvement of C5a in the progression of experimental arthritis with Porphyromonas gingivalis infection in SKG mice
Syuichi Munenaga, Kazuhisa Ouhara, Yuta Hamamoto, Mikihito Kajiya, Katsuhiro Takeda, Satoshi Yamasaki, Toshihisa Kawai, Noriyoshi Mizuno, Tsuyoshi Fujita, Eiji Sugiyama, Hidemi Kurihara
Correction to: Is the exposure to bisphosphonates or osteoporosis the predictor of spinal radiographic progression in ankylosing spondylitis?
Giovanni Orsolini, Giovanni Adami, Maurizio Rossini, Angelo Fassio, Alessandro Giollo, Cristian Caimmi, Luca Idolazzi, Davide Gatti, Ombretta Viapiana
Intrauterine fetal deaths related to antiphospholipid syndrome: a descriptive study of 65 women
Mériem Belhocine, Laetitia Coutte, Nicolas Martin Silva, Nathalie Morel, Gaëlle Guettrot-Imbert, Romain Paule, Claire Le Jeunne, Micaela Fredi, Michel Dreyfus, Jean-Charles Piette, Odile Souchaud-Debouverie, Catherine Deneux-Tharaux, Vassilis Tsatsaris, Emmanuelle Pannier, Véronique Le Guern, Nathalie Costedoat-Chalumeau
Knee pain as a predictor of structural progression over 4 years: data from the Osteoarthritis Initiative, a prospective cohort study
Yuanyuan Wang, Andrew J. Teichtahl, François Abram, Sultana Monira Hussain, Jean-Pierre Pelletier, Flavia M. Cicuttini, Johanne Martel-Pelletier
The inflammatory response in the regression of lumbar disc herniation
Carla Cunha, Ana J. Silva, Paulo Pereira, Rui Vaz, Raquel M. Gonçalves, Mário A. Barbosa
VZV-specific T-cell levels in patients with rheumatic diseases are reduced and differentially influenced by antirheumatic drugs
David Schub, Gunter Assmann, Urban Sester, Martina Sester, Tina Schmidt
Functional consultation and exercises improve grip strength in osteoarthritis of the hand – a randomised controlled trial
Michaela A. Stoffer-Marx, Meike Klinger, Simone Luschin, Silvia Meriaux-Kratochvila, Monika Zettel-Tomenendal, Valerie Nell-Duxneuner, Jochen Zwerina, Ingvild Kjeken, Marion Hackl, Sylvia Öhlinger, Anthony Woolf, Kurt Redlich, Josef S. Smolen, Tanja A. Stamm
Polydatin effectively attenuates disease activity in lupus-prone mouse models by blocking ROS-mediated NET formation
Pan Liao, Yi He, Fangyuan Yang, Guihu Luo, Jian Zhuang, Zeqing Zhai, Lili Zhuang, Zhuomiao Lin, Jiehuang Zheng, Erwei Sun
How much allopurinol does it take to get to target urate? Comparison of actual dose with creatinine clearance-based dose
Lisa K. Stamp, Peter T. Chapman, Murray L. Barclay, Anne Horne, Christopher Frampton, Paul Tan, Jill Drake, Nicola Dalbeth
The multi-biomarker disease activity score tracks response to rituximab treatment in rheumatoid arthritis patients: a post hoc analysis of three cohort studies
Nadia M. T. Roodenrijs, Maria J. H. de Hair, Gill Wheater, Mohsen Elshahaly, Janneke Tekstra, Y. K. Onno Teng, Floris P. J. G. Lafeber, Ching Chang Hwang, Xinyu Liu, Eric H. Sasso, Jacob M. van Laar
Musculoskeletal manifestations occur predominantly in patients with later-onset familial Mediterranean fever: Data from a multicenter, prospective national cohort study in Japan
Yushiro Endo, Tomohiro Koga, Midori Ishida, Yuya Fujita, Sosuke Tsuji, Ayuko Takatani, Toshimasa Shimizu, Remi Sumiyoshi, Takashi Igawa, Masataka Umeda, Shoichi Fukui, Ayako Nishino, Shin-ya Kawashiri, Naoki Iwamoto, Kunihiro Ichinose, Mami Tamai, Hideki Nakamura, Tomoki Origuchi, Kazunaga Agematsu, Akihiro Yachie, Junya Masumoto, Kiyoshi Migita, Atsushi Kawakami
Comorbidities in polymyalgia rheumatica: a systematic review
Richard Partington, Toby Helliwell, Sara Muller, Alyshah Abdul Sultan, Christian Mallen
Aberrant expression of interleukin-23-regulated miRNAs in T cells from patients with ankylosing spondylitis
Ning-Sheng Lai, Hui-Chun Yu, Chien-Hsueh Tung, Kuang-Yung Huang, Hsien-Bin Huang, Ming-Chi Lu
Sequence of joint tissue inflammation during rheumatoid arthritis development
R. M. ten Brinck, H. W. van Steenbergen, A. H. M. van der Helm–van Mil
Induction of chronic destructive arthritis in SCID mice by arthritogenic fibroblast-like synoviocytes derived from mice with antigen-induced arthritis
Oliver Frey, Marion Hückel, Mieczyslaw Gajda, Peter K. Petrow, Rolf Bräuer
Long-term, health-enhancing physical activity is associated with reduction of pain but not pain sensitivity or improved exercise-induced hypoalgesia in persons with rheumatoid arthritis
Monika Löfgren, Christina H. Opava, Ingrid Demmelmaier, Cecilia Fridén, Ingrid E. Lundberg, Birgitta Nordgren, Eva Kosek
The effect of the cholinergic anti-inflammatory pathway on collagen-induced arthritis involves the modulation of dendritic cell differentiation
Di Liu, Tong Li, Hui Luo, Xiaoxia Zuo, Sijia Liu, Shiyao Wu
The presence of anti-nuclear antibodies alone is associated with changes in B cell activation and T follicular helper cells similar to those in systemic autoimmune rheumatic disease
Yuriy Baglaenko, Nan-Hua Chang, Sindhu R. Johnson, Waleed Hafiz, Kieran Manion, Dario Ferri, Babak Noamani, Dennisse Bonilla, Sina Rusta-Sellehy, Larissa Lisnevskaia, Earl Silverman, Arthur Bookman, Carolina Landolt-Marticorena, Joan Wither
Standardisation of synovial biopsy analyses in rheumatic diseases: a consensus of the EULAR Synovitis and OMERACT Synovial Tissue Biopsy Groups
Aurélie Najm, Benoît Le Goff, Carl Orr, Rogier Thurlings, Juan D. Cañete, Frances Humby, Stefano Alivernini, Antonio Manzo, Søren Andreas Just, Vasco C. Romão, Veit Krenn, Ulf Müller-Ladner, Olga Addimanda, Sander W. Tas, Maria Stoenoiu, Laurent Meric de Bellefon, Patrick Durez, Vibeke Strand, Mihir D. Wechalekar, Joao E. Fonseca, Bernard Lauwerys, Ursula Fearon, Douglas J. Veale
Carotid artery volumetric measures associate with clinical ten-year cardiovascular (CV) risk scores and individual traditional CV risk factors in rheumatoid arthritis; a carotid-MRI feasibility study
Lesley-Anne Bissell, Bara Erhayiem, Graham Fent, Elizabeth M. A. Hensor, Agata Burska, Helena Donica, Sven Plein, Maya H. Buch, John P. Greenwood, Jacqueline Andrews
Prevalence of comorbidities in systemic sclerosis versus rheumatoid arthritis: a comparative, multicenter, matched-cohort study
Stylianos Panopoulos, Maria Tektonidou, Alexandros A. Drosos, Stamatis-Nick Liossis, Theodoros Dimitroulas, Alexandros Garyfallos, Lazaros Sakkas, Dimitrios Boumpas, Paraskevi V. Voulgari, Dimitrios Daoussis, Konstantinos Thomas, Georgios Georgiopoulos, Georgios Vosvotekas, Dimitrios Vassilopoulos, Petros P. Sfikakis
Association between autophagy and inflammation in patients with rheumatoid arthritis receiving biologic therapy
Yi-Ming Chen, Chun-Yu Chang, Hsin-Hua Chen, Chia-Wei Hsieh, Kuo-Tung Tang, Meng-Chun Yang, Joung-Liang Lan, Der-Yuan Chen
Improved patient-reported outcomes in patients with psoriatic arthritis treated with abatacept: results from a phase 3 trial
Vibeke Strand, Evo Alemao, Thomas Lehman, Alyssa Johnsen, Subhashis Banerjee, Harris A. Ahmad, Philip J. Mease
The risks of cancer development in systemic lupus erythematosus (SLE) patients: a systematic review and meta-analysis
Lebin Song, Yi Wang, Jiayi Zhang, Ninghong Song, Xiaoyun Xu, Yan Lu
Correction to: Incidence of giant cell arteritis in Western Norway 1972-2012: a retrospective cohort study
L. K. Brekke, A. P. Diamantopoulos, B.-T. Fevang, J. Aβmus, E. Esperø, C. G. Gjesdal
Secukinumab provides sustained PASDAS-defined remission in psoriatic arthritis and improves health-related quality of life in patients achieving remission: 2-year results from the phase III FUTURE 2 study
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