Erschienen in:
28.05.2020 | ASO Author Reflections
ASO Author Reflections: Elevated Preoperative Specific Growth Rate is Associated with Shortened Survival After Resection for Pancreatic Neuroendocrine Tumors
verfasst von:
Jordan J. Baechle, BS, Paula Marincola Smith, MD, Kamran Idrees, MD, MSCI, MMHC, FACS
Erschienen in:
Annals of Surgical Oncology
|
Ausgabe 10/2020
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Excerpt
Pancreatic neuroendocrine tumors (PNETs) generally are considered indolent with a favorable prognosis. However, an estimated 10% exhibit aggressive behavior with associated poor prognosis.
1 Although surgical resection is the mainstay of treatment for PNETs, current treatment guidelines advocate expectant management of small (≤ 2 cm) nonfunctional tumors with serial surveillance imaging.
2–4 Incidental diagnosis is increasingly common,
5 and a need remains to identify patients with aggressive PNET variants, particularly among patients with small nonfunctional tumors managed nonoperatively who may benefit from earlier surgical intervention. …