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Irish Journal of Medical Science (1971 -)

Erschienen in:

01.09.2011 | Review Article

Aspirin for lower limb arthroplasty thromboprophylaxis: review of international guidelines

verfasst von: C. L. Donohoe, M. K. Sayana, R. Thakral, D. M. Niall

Erschienen in: Irish Journal of Medical Science (1971 -) | Ausgabe 3/2011

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Abstract

Introduction

Aspirin is one of the pharmacological agents used for thromboprophylaxis.

Materials and methods

National thromboprophylaxis guidelines, peer-reviewed studies and data from national joint register of England and Wales were analysed for evidence regarding the efficacy of aspirin versus other agents in thromboprophylaxis and the recommendations of guidelines.

Results

Two of five guidelines reviewed recommend the use of aspirin for thromboprophylaxis. Aspirin is used as thromboprophylactic agent in approximately 25% of patients undergoing total hip and total knee arthroplasty in year 2006 in England and Wales. There is no difference in mortality in these patients compared to patients on other pharmacological agents.

Conclusion

There is conflicting evidence and differences in interpretation of the data from the literature. If specific outcome measures and complications such as symptomatic DVT, PE and bleeding were logged in arthroplasty registers, the resulting data would be useful in individualised decision-making.

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Titel: Aspirin for lower limb arthroplasty thromboprophylaxis: review of international guidelines
verfasst von: C. L. Donohoe
M. K. Sayana
R. Thakral
D. M. Niall
Publikationsdatum: 01.09.2011
Verlag: Springer-Verlag
Erschienen in: Irish Journal of Medical Science (1971 -) / Ausgabe 3/2011
Print ISSN: 0021-1265
Elektronische ISSN: 1863-4362
DOI: https://doi.org/10.1007/s11845-010-0658-0

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Abstract

Introduction

Materials and methods

Results

Conclusion

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