nach oben

Erschienen in:

23.06.2020 | Original Contribution

Assessing the impact of drinking water iodine concentrations on the iodine intake of Chinese pregnant women living in areas with restricted iodized salt supply

verfasst von: M. Gao, W. Chen, S. Dong, Y. Chen, Q. Zhang, H. Sun, Y. Zhang, W. Wu, Z. Pan, S. Gao, L. Lin, J. Shen, L. Tan, G. Wang, W. Zhang

Erschienen in: European Journal of Nutrition | Ausgabe 2/2021

Einloggen, um Zugang zu erhalten

Abstract

Purpose

The supply of non-iodized salt and the water improvement project have been conducted to reduce the iodine concentration in drinking water in areas with elevated water iodine. We aimed to assess the impact of water iodine concentration (WIC) on the iodine intake of pregnant women in areas with restricted iodized salt supply, and determine the cutoff values of WIC in areas with non-iodized salt supply.

Methods

Overall, 534 pregnant women who attended routine antenatal outpatient visits in Zibo Maternal and Child Health Hospital in Gaoqing County were recruited. The 24-h urine iodine excretion (UIE) in 534 samples and the iodine concentration in 534 drinking water samples were estimated. Urinary iodine excretion, daily iodine intake, and daily iodine intake from drinking water (WII) were calculated. The relationship between WIC and daily iodine take was analyzed.

Results

The median WIC, spot urine iodine concentration (UIC), and 24-h UIE were 17 (6, 226) μg/L, 145 (88, 267) μg/L, and 190 (110, 390) μg/day, respectively. A significant positive correlation was found between WIC and UIE (R² = 0.265, p < 0.001) and UIC (R² = 0.261, p < 0.001). The contribution rate of WII to total iodine intake increased from 3.0% in the group with WIC of < 10 μg/L to 45.7% in the group with WIC of 50–99 μg/L.

Conclusion

The iodine content in drinking water is the major iodine source in pregnant women living in high-water iodine areas where iodized salt supply is restricted. The contribution rate of daily iodine intake from drinking water increases with the increase in water iodine concentration.

Laurberg P, Bulow Pedersen I, Knudsen N, Ovesen L, Andersen S (2001) Environmental iodine intake affects the type of nonmalignant thyroid disease. Thyroid 11(5):457–469. https://doi.org/10.1089/105072501300176417CrossRefPubMed

Yarrington C, Pearce EN (2011) Iodine and pregnancy. J Thyroid Res 2011:934104. https://doi.org/10.4061/2011/934104CrossRefPubMedPubMedCentral

WHO, UNICEF (2007) Assessment of iodine deficiency disorders and monitoring their elimination: a guide for programme managers, 3rd edn. WHO, Geneva

Teas J, Braverman LE, Kurzer MS, Pino S, Hurley TG, Hebert JR (2007) Seaweed and soy: companion foods in Asian cuisine and their effects on thyroid function in American women. J Med Food 10(1):90–100. https://doi.org/10.1089/jmf.2005.056CrossRefPubMed

Katagiri R, Yuan X, Kobayashi S, Sasaki S (2017) Effect of excess iodine intake on thyroid diseases in different populations: a systematic review and meta-analyses including observational studies. PLoS ONE 12(3):e0173722. https://doi.org/10.1371/journal.pone.0173722CrossRefPubMedPubMedCentral

Zava TT, Zava DT (2011) Assessment of Japanese iodine intake based on seaweed consumption in Japan: a literature-based analysis. Thyroid Res 4:14. https://doi.org/10.1186/1756-6614-4-14CrossRefPubMedPubMedCentral

Li M, Liu DR, Qu CY, Zhang PY, Qian QD, Zhang CD, Jia QZ, Wang HX, Eastman CJ, Boyages SC et al (1987) Endemic goitre in central China caused by excessive iodine intake. Lancet 2(8553):257–259PubMed

Suzuki H, Higuchi T, Sawa K, Ohtaki S, Horiuchi Y (1965) “Endemic coast goitre” in Hokkaido. Jpn Acta Endocrinol (Copenh) 50(2):161–176CrossRef

Sang Z, Chen W, Shen J, Tan L, Zhao N, Liu H, Wen S, Wei W, Zhang G, Zhang W (2013) Long-term exposure to excessive iodine from water is associated with thyroid dysfunction in children. J Nutr 143(12):2038–2043. https://doi.org/10.3945/jn.113.179135CrossRefPubMed

10.

Liu P, Liu L, Shen H, Jia Q, Wang J, Zheng H, Ma J, Zhou D, Liu S, Su X (2014) The standard, intervention measures and health risk for high water iodine areas. PLoS ONE 9(2):e89608. https://doi.org/10.1371/journal.pone.0089608CrossRefPubMedPubMedCentral

11.

Xiao Y, Sun H, Li C, Li Y, Peng S, Fan C, Teng W, Shan Z (2018) Effect of iodine nutrition on pregnancy outcomes in an iodine-sufficient area in China. Biol Trace Elem Res 182(2):231–237. https://doi.org/10.1007/s12011-017-1101-4CrossRefPubMed

12.

Kassim IA, Moloney G, Busili A, Nur AY, Paron P, Jooste P, Gadain H, Seal AJ (2014) Iodine intake in Somalia is excessive and associated with the source of household drinking water. J Nutr 144(3):375–381. https://doi.org/10.3945/jn.113.176693CrossRefPubMedPubMedCentral

13.

Farebrother J, Zimmermann MB, Abdallah F, Assey V, Fingerhut R, Gichohi-Wainaina WN, Hussein I, Makokha A, Sagno K, Untoro J, Watts M, Andersson M (2018) Effect of excess iodine intake from iodized salt and/or groundwater iodine on thyroid function in nonpregnant and pregnant women, infants, and children: a multicenter study in East Africa. Thyroid 28(9):1198–1210. https://doi.org/10.1089/thy.2018.0234CrossRefPubMed

14.

GB/T19380 (2016) Determination and classification of the areas of high water iodine and the endemic areas of iodine excess goiter. China Standards Press, Beijing

15.

Shen H, Liu S, Sun D, Zhang S, Su X, Shen Y, Han H (2011) Geographical distribution of drinking-water with high iodine level and association between high iodine level in drinking-water and goitre: a Chinese national investigation. Br J Nutr 106(2):243–247. https://doi.org/10.1017/S0007114511000055CrossRefPubMed

16.

Andersen S, Petersen SB, Laurberg P (2002) Iodine in drinking water in Denmark is bound in humic substances. Eur J Endocrinol 147(5):663–670. https://doi.org/10.1530/eje.0.1470663CrossRefPubMed

17.

Andersen S, Guan H, Teng W, Laurberg P (2009) Speciation of iodine in high iodine groundwater in china associated with goitre and hypothyroidism. Biol Trace Elem Res 128(2):95–103. https://doi.org/10.1007/s12011-008-8257-xCrossRefPubMed

18.

Gao J, Zhang Z, Hu Y, Bian J, Jiang W, Wang X, Sun L, Jiang Q (2014) Geographical distribution patterns of iodine in drinking-water and its associations with geological factors in Shandong Province, China. Int J Environ Res Public Health 11(5):5431–5444. https://doi.org/10.3390/ijerph110505431CrossRefPubMedPubMedCentral

19.

Xu C, Guo X, Tang J, Guo X, Lu Z, Zhang J, Bi Z (2016) Iodine nutritional status in the adult population of Shandong Province (China) prior to salt reduction program. Eur J Nutr 55(5):1933–1941. https://doi.org/10.1007/s00394-015-1009-8CrossRefPubMed

20.

Chen Y, Chen W, Du C, Fan L, Wang W, Gao M, Zhang Y, Cui T, Hao Y, Pearce EN, Wang C, Zhang W (2019) Iodine nutrition and thyroid function in pregnant women exposed to different iodine sources. Biol Trace Elem Res 190(1):52–59. https://doi.org/10.1007/s12011-018-1530-8CrossRefPubMed

21.

Jahreis G, Hausmann W, Kiessling G, Franke K, Leiterer M (2001) Bioavailability of iodine from normal diets rich in dairy products—results of balance studies in women. Exp Clin Endocrinol Diabetes 109(3):163–167. https://doi.org/10.1055/s-2001-14840CrossRefPubMed

22.

Institute of Medicine (2001) Dietary reference intakes for vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc. National Academies Press, Washington

23.

Society; CN (2013) Chinese dietarty reference intakes (2013). Science Press, Beijing

24.

Shi X, Han C, Li C, Mao J, Wang W, Xie X, Li C, Xu B, Meng T, Du J, Zhang S, Gao Z, Zhang X, Fan C, Shan Z, Teng W (2015) Optimal and safe upper limits of iodine intake for early pregnancy in iodine-sufficient regions: a cross-sectional study of 7190 pregnant women in China. J Clin Endocrinol Metab 100(4):1630–1638. https://doi.org/10.1210/jc.2014-3704CrossRefPubMed

25.

Henjum S, Barikmo I, Gjerlaug AK, Mohamed-Lehabib A, Oshaug A, Strand TA, Torheim LE (2010) Endemic goitre and excessive iodine in urine and drinking water among Saharawi refugee children. Public Health Nutr 13(9):1472–1477. https://doi.org/10.1017/S1368980010000650CrossRefPubMed

26.

Watts MJ, Middleton DRS, Marriott A, Humphrey OS, Hamilton E, McCormack V, Menya D, Farebrother J, Osano O (2019) Iodine status in western Kenya: a community-based cross-sectional survey of urinary and drinking water iodine concentrations. Environ Geochem Health. https://doi.org/10.1007/s10653-019-00352-0CrossRefPubMed

27.

Aakre I, Bjoro T, Norheim I, Strand TA, Barikmo I, Henjum S (2015) Excessive iodine intake and thyroid dysfunction among lactating Saharawi women. J Trace Elem Med Biol 31:279–284. https://doi.org/10.1016/j.jtemb.2014.09.009CrossRefPubMed

28.

Hussein IS, Min Y, Ghebremeskel K, Gaffar AM (2012) Iodine status and fish intake of Sudanese schoolchildren living in the Red Sea and White Nile regions. Public Health Nutr 15(12):2265–2271. https://doi.org/10.1017/S1368980012000833CrossRefPubMed

29.

Fuge R (2013) Soils and iodine deficiency. In: Selinus O (ed) Essentials of medical geology revised edition. Springer, Dordrecht, pp 417–432CrossRef

30.

Rasmussen LB, Larsen EH, Ovesen L (2000) Iodine content in drinking water and other beverages in Denmark. Eur J Clin Nutr 54(1):57–60. https://doi.org/10.1038/sj.ejcn.1600893CrossRefPubMed

31.

Teng W, Shan Z, Teng X, Guan H, Li Y, Teng D, Jin Y, Yu X, Fan C, Chong W, Yang F, Dai H, Yu Y, Li J, Chen Y, Zhao D, Shi X, Hu F, Mao J, Gu X, Yang R, Tong Y, Wang W, Gao T, Li C (2006) Effect of iodine intake on thyroid diseases in China. N Engl J Med 354(26):2783–2793. https://doi.org/10.1056/NEJMoa054022CrossRefPubMed

32.

Leung AM, Avram AM, Brenner AV, Duntas LH, Ehrenkranz J, Hennessey JV, Lee SL, Pearce EN, Roman SA, Stagnaro-Green A, Sturgis EM, Sundaram K, Thomas MJ, Wexler JA (2015) Potential risks of excess iodine ingestion and exposure: statement by the american thyroid association public health committee. Thyroid 25(2):145–146. https://doi.org/10.1089/thy.2014.0331CrossRefPubMedPubMedCentral

33.

Nicola JP, Carrasco N, Masini-Repiso AM (2015) Dietary I(-) absorption: expression and regulation of the Na(+)/I(-) symporter in the intestine. Vitam Horm 98:1–31. https://doi.org/10.1016/bs.vh.2014.12.002CrossRefPubMed

34.

Birke M, Reimann C, Albanese S, Andersson M, Banks D, Batista M, Bel-lan A, Bityukova L, Cicchella D, Demetriades A, Devic N, Dinelli E, Ďuriš M, Filzmoser P, Flight D, Flynn R, Frengstad B, Gilucis A, Glatte WB (2010) Geochemistry of European bottled water. Borntraeger Science Publishers, Stuttgart

35.

Voutchkova DD, Kristiansen SM, Hansen B, Ernstsen V, Sorensen BL, Esbensen KH (2014) Iodine concentrations in Danish groundwater: historical data assessment 1933–2011. Environ Geochem Health 36(6):1151–1164. https://doi.org/10.1007/s10653-014-9625-4CrossRefPubMed

36.

Barikmo I, Henjum S, Dahl L, Oshaug A, Torheim E (2011) Environmental implication of iodine in water, milk and other foods used in Saharawi refugees camps in Tindouf, Algeria. J Food Compost Anal 24(4–5):637–641. https://doi.org/10.1016/j.jfca.2010.10.003CrossRef

37.

Watts MJ, O'Reilly J, Maricelli A, Coleman A, Ander EL, Ward NI (2010) A snapshot of environmental iodine and selenium in La Pampa and San Juan provinces of Argentina. J Geochem Explor 107(2):87–93. https://doi.org/10.1016/j.gexplo.2009.11.002CrossRef

38.

Watts MJ, Joy EJ, Young SD, Broadley MR, Chilimba AD, Gibson RS, Siyame EW, Kalimbira AA, Chilima B, Ander EL (2015) Iodine source apportionment in the Malawian diet. Sci Rep 5:15251. https://doi.org/10.1038/srep15251CrossRefPubMedPubMedCentral

39.

Chen W, Li X, Wu Y, Bian J, Shen J, Jiang W, Tan L, Wang X, Wang W, Pearce EN, Zimmermann MB, Carriquiry AL, Zhang W (2017) Associations between iodine intake, thyroid volume, and goiter rate in school-aged Chinese children from areas with high iodine drinking water concentrations. Am J Clin Nutr 105(1):228–233. https://doi.org/10.3945/ajcn.116.139725CrossRefPubMed

40.

Vejbjerg P, Knudsen N, Perrild H, Laurberg P, Andersen S, Rasmussen LB, Ovesen L, Jorgensen T (2009) Estimation of iodine intake from various urinary iodine measurements in population studies. Thyroid 19(11):1281–1286. https://doi.org/10.1089/thy.2009.0094CrossRefPubMed

41.

Andersen S, Karmisholt J, Pedersen KM, Laurberg P (2008) Reliability of studies of iodine intake and recommendations for number of samples in groups and in individuals. Br J Nutr 99(4):813–818. https://doi.org/10.1017/S0007114507842292CrossRefPubMed

42.

Nath SK, Moinier B, Thuillier F, Rongier M, Desjeux JF (1992) Urinary excretion of iodide and fluoride from supplemented food grade salt. Int J Vitam Nutr Res 62(1):66–72PubMed

Titel: Assessing the impact of drinking water iodine concentrations on the iodine intake of Chinese pregnant women living in areas with restricted iodized salt supply
verfasst von: M. Gao
W. Chen
S. Dong
Y. Chen
Q. Zhang
H. Sun
Y. Zhang
W. Wu
Z. Pan
S. Gao
L. Lin
J. Shen
L. Tan
G. Wang
W. Zhang
Publikationsdatum: 23.06.2020
Verlag: Springer Berlin Heidelberg
Erschienen in: European Journal of Nutrition / Ausgabe 2/2021
Print ISSN: 1436-6207
Elektronische ISSN: 1436-6215
DOI: https://doi.org/10.1007/s00394-020-02308-y

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

^{Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag}

Kostenlos registrieren

Neu im Fachgebiet Innere Medizin

25.04.2024 | Hypotonie | Nachrichten

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Springer Medizin

Assessing the impact of drinking water iodine concentrations on the iodine intake of Chinese pregnant women living in areas with restricted iodized salt supply

Abstract

Purpose

Methods

Results

Conclusion

Leitlinien kompakt für die Innere Medizin

Neu im Fachgebiet Innere Medizin

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

Viel Bewegung in der Parkinsonforschung

Adjuvante Immuntherapie verlängert Leben bei RCC

Update Innere Medizin

Springer Medizin

Abstract

Purpose

Methods

Results

Conclusion

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 2/2021

Distribution of daily protein intake across meals and lower extremity functioning in community-dwelling Spanish older adults: a prospective cohort study

Correction to: Dietary folate intake and metabolic syndrome in participants of PREDIMED‑Plus study: a cross‑sectional study

Dietary folate intake and metabolic syndrome in participants of PREDIMED-Plus study: a cross-sectional study

Correction to: Sex‑dependent association between selenium status and cognitive performance in older adults

Effectiveness of wheat soya blend supplementation during pregnancy and lactation on pregnancy outcomes and nutritional status of their infants at 6 months of age in Thatta and Sujawal districts of Sindh, Pakistan: a cluster randomized-controlled trial

A systematic review and meta-analysis of 24-h urinary output of children and adolescents: impact on the assessment of iodine status using urinary biomarkers—don’t forget creatinine

Leitlinien kompakt für die Innere Medizin

Neu im Fachgebiet Innere Medizin

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

Viel Bewegung in der Parkinsonforschung

Adjuvante Immuntherapie verlängert Leben bei RCC

Update Innere Medizin