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Erschienen in: Tumor Biology 7/2014

01.07.2014 | Research Article

Association of periodontal disease with oral cancer: a meta-analysis

verfasst von: Qi-Wei Yao, Dong-Sheng Zhou, Hong-Juan Peng, Ping Ji, De-Sheng Liu

Erschienen in: Tumor Biology | Ausgabe 7/2014

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Abstract

The objective is to evaluate the association of periodontal disease with the risk of oral cancer. Literature retrieval, selection and assessment, data extraction, and meta-analyses were performed according to the RevMan 5.0 guidelines. In the meta-analysis, we utilized random-effect model to pool the odds ratio (OR) according to the test of heterogeneity. A total of five eligible studies included 1,191 oral cancer patients and 1,992 healthy control subjects were analyzed. By meta-analysis, we found a significant association of periodontal disease with oral cancer [OR = 3.53, 95 % CI (1.52–8.23); P = 0.003]. Patients with periodontal disease have increased susceptibility to oral cancer.
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Metadaten
Titel
Association of periodontal disease with oral cancer: a meta-analysis
verfasst von
Qi-Wei Yao
Dong-Sheng Zhou
Hong-Juan Peng
Ping Ji
De-Sheng Liu
Publikationsdatum
01.07.2014
Verlag
Springer Netherlands
Erschienen in
Tumor Biology / Ausgabe 7/2014
Print ISSN: 1010-4283
Elektronische ISSN: 1423-0380
DOI
https://doi.org/10.1007/s13277-014-1951-8

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