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Neuroradiology

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08.05.2020 | Diagnostic Neuroradiology

Automated ASPECT scoring in acute ischemic stroke: comparison of three software tools

verfasst von: Philip Hoelter, Iris Muehlen, Philipp Goelitz, Vanessa Beuscher, Stefan Schwab, Arnd Doerfler

Erschienen in: Neuroradiology | Ausgabe 10/2020

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Abstract

Purpose

Various software applications offer support in the diagnosis of acute ischemic stroke (AIS), yet it remains unclear whether the performance of these tools is comparable to each other. Our study aimed to evaluate three fully automated software applications for Alberta Stroke Program Early CT (ASPECT) scoring (Syngo.via Frontier ASPECT Score Prototype V2, Brainomix e-ASPECTS® and RAPID ASPECTS) in AIS patients.

Methods

Retrospectively, 131 patients with large vessel occlusion (LVO) of the middle cerebral artery or the internal carotid artery, who underwent endovascular therapy (EVT), were included. Pre-interventional non-enhanced CT (NECT) datasets were assessed in random order using the automated ASPECT software and by three experienced neuroradiologists in consensus. Interclass correlation coefficient (ICC), Bland-Altman, and receiver operating characteristics (ROC) were applied for statistical analysis.

Results

Median ASPECTS of the expert consensus reading was 8 (7–10). Highest correlation was between the expert read and Brainomix (r = 0.871 (0.818, 0.909), p < 0.001). Correlation between expert read and Frontier V2 (r = 0.801 (0.719, 0.859), p < 0.001) and between expert read and RAPID (r = 0.777 (0.568, 0.871), p < 0.001) was high, respectively. There was a high correlation among the software tools (Frontier V2 and Brainomix: r = 0.830 (0.760, 0.880), p < 0.001; Frontier V2 and RAPID: r = 0.847 (0.693, 0.913), p < 0.001; Brainomix and RAPID: r = 0.835 (0.512, 0.923), p < 0.001). An ROC curve analysis revealed comparable accuracy between the applications and expert consensus reading (Brainomix: AUC = 0.759 (0.670–0.848), p < 0.001; Frontier V2: AUC = 0.752 (0.660–0.843), p < 0.001; RAPID: AUC = 0.734 (0.634–0.831), p < 0.001).

Conclusion

Overall, there is a convincing yet developable grade of agreement between current ASPECT software evaluation tools and expert evaluation with regard to ASPECT assessment in AIS.

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Titel: Automated ASPECT scoring in acute ischemic stroke: comparison of three software tools
verfasst von: Philip Hoelter
Iris Muehlen
Philipp Goelitz
Vanessa Beuscher
Stefan Schwab
Arnd Doerfler
Publikationsdatum: 08.05.2020
Verlag: Springer Berlin Heidelberg
Erschienen in: Neuroradiology / Ausgabe 10/2020
Print ISSN: 0028-3940
Elektronische ISSN: 1432-1920
DOI: https://doi.org/10.1007/s00234-020-02439-3

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Automated ASPECT scoring in acute ischemic stroke: comparison of three software tools

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Purpose

Methods

Results

Conclusion

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