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International Journal of Clinical Oncology

Erschienen in:

27.06.2017 | Review Article

Biphasic malignant tumours of the abdominal cavity

verfasst von: L. Max Almond, Adrian T. Warfield, Anant Desai, David Gourevitch, Samuel J. Ford

Erschienen in: International Journal of Clinical Oncology | Ausgabe 4/2017

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Abstract

Carcinosarcomas (CS) are uncommon, highly aggressive, biphasic tumours consisting of both sarcomatous and carcinomatous elements. They appear to originate from a common cell of origin, either via transformation from a single premature precursor or conversion of a mature epithelial cell through an epithelial–mesenchymal transition. CS should be considered a unique cancer subtype with cells typically displaying diffuse mitotic activity and widespread atypical mitoses predisposing to early metastasis and a tendency to local recurrence following resection. This review addresses the pathophysiology of CS and discusses its presentation, natural history and management at a variety of sites within the abdominal cavity and retroperitoneum.

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Titel: Biphasic malignant tumours of the abdominal cavity
verfasst von: L. Max Almond
Adrian T. Warfield
Anant Desai
David Gourevitch
Samuel J. Ford
Publikationsdatum: 27.06.2017
Verlag: Springer Japan
Erschienen in: International Journal of Clinical Oncology / Ausgabe 4/2017
Print ISSN: 1341-9625
Elektronische ISSN: 1437-7772
DOI: https://doi.org/10.1007/s10147-017-1153-7

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Biphasic malignant tumours of the abdominal cavity

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