Erschienen in:
01.09.2005 | Short Report
Bleeding diathesis in a child with normal screening tests: think about fibrinolysis
verfasst von:
Vanessa Largent, Véronique Deneys, Bénédicte Brichard, Christophe Chantrain, Christiane Vermylen
Erschienen in:
European Journal of Pediatrics
|
Ausgabe 9/2005
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Excerpt
A 5-year-old girl was referred to our department for evaluation because of a history of recurrent episodes of epistaxis and subcutaneous bleeding. As to her personal history, the umbilical cord showed, at birth, only one vein and one artery. She was first referred at the age of 3 years for asymptomatic thrombocytopenia with platelets varying from 97,000 to 238,000/mm3 (reference range 150,000–300,000/mm3). Screening studies did not show any abnormalities (normal haemostatic screening studies, IgM negative for measles, mumps and rubella, auto-antibodies negative, direct platelet antibodies negative, normal humoral and cellular immunity tests, normal platelet morphology). The family history was positive for a bleeding diathesis as the mother developed purpura at the age of 3 years and also presented an asymptomatic thrombocytopenia at the age of 15 years. The parents were not consanguineous. …