Introduction
Bone marrow-derived cells and ocular neovascularization
Bone marrow-derived cells and corneal neovascularization
Bone marrow-derived cells and retinal neovascularization
Bone marrow-derived cells and choroidal neovascularization
Proportions and time frame of bone marrow-derived cells’ contribution to ocular neovascularization
Molecular mechanisms of bone marrow-derived cells’ contribution to ocular neovascularization
Mobilization of bone marrow-derived cells from bone marrow to circulation
Migration of bone marrow-derived cells from circulation to ocular lesions
Adhesion of bone marrow-derived cells in ocular neovascularization
Differentiation of bone marrow-derived cells into neovascular cells
Cytokines from bone marrow-derived cells
MicroRNAs in bone marrow-derived cells’ contribution to ocular neovascularization
MicroRNA | Target genes | Type of ocular neovascularization | References |
---|---|---|---|
MiR-126 | VEGF, HIF-1a, IGF | RNV, CNV | |
MiR-200b | VEGF, OXR1 | RNV | |
MiR-31 | PDGF-B, HIF-1α | RNV, CNV | [72] |
MiR-150 | VEGF, PDGF-B | RNV, CNV | [72] |
MiR-184 | Fzd4 | RNV, CNV | [72] |
MiR-132 | Ras-GAP | CV | [71] |