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Angiogenesis OnlineFirst articles

04.02.2020 | Original Paper

Decylubiquinone suppresses breast cancer growth and metastasis by inhibiting angiogenesis via the ROS/p53/ BAI1 signaling pathway

Breast cancer is one of the most common cancers worldwide with a rising incidence, and is the leading cause of cancer-related death among females. Angiogenesis plays an important role in breast cancer growth and metastasis. In this study, we …

29.01.2020 | Brief Communication

Matrix deformations around angiogenic sprouts correlate to sprout dynamics and suggest pulling activity

Angiogenesis is the formation of new blood vessels from the pre-existing vasculature. It is essential for normal tissue growth and regeneration, and also plays a key role in many diseases [Carmeliet in Nat Med 9:653–660, 2003]. Cytoskeletal …

28.01.2020 | Letter to the Editor

Age-related structural alterations of skeletal muscles and associated capillaries

Aging is associated with a progressive decline in muscle mass, strength, and quality. We have previously demonstrated the important role of the blood vasculature system in ultraviolet (UV) light-induced changes in skin and its molecular …

28.01.2020 | Perspective

Positive and negative feedback mechanisms controlling tip/stalk cell identity during sprouting angiogenesis

Vascular endothelial growth factor-A (VEGF-A/VEGF) interaction with VEGF receptor 2 (VEGFR2) is key for sprouting angiogenesis in health and disease. VEGF/VEGFR2 signaling promotes endothelial proliferation and migration, as well as the …

18.12.2019 | Review Paper

Role of VEGFs in metabolic disorders

Obesity and metabolic disorders are important public health problems. In this review, the role of vasculature network and VEGF in the adipose tissue maintenance and supplementation is discussed. Angiogenesis is a key process implicated in …

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Angiogenesis is an international peer-reviewed journal devoted to the publication of top quality original articles and reviews on the cellular and molecular mechanisms that regulate angiogenesis in physiological and pathological conditions. As a central source for rapid communications representing the full spectrum of angiogenesis research, this multidisciplinary journal publishes innovative experimental studies using molecular, in vitro, animal model systems and clinical investigations of angiogenic diseases. Angiogenesis also reports on novel therapeutic approaches for promoting or inhibiting angiogenesis as well as new markers and techniques for disease diagnosis and prognosis.

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