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Angiogenesis OnlineFirst articles

14.10.2020 | COVID-19 | Original Paper Open Access

Microvascular dysfunction in COVID-19: the MYSTIC study

Despite about 26 million infections and nearly 870,000 deaths worldwide (04 September 2020), the pathophysiological pathways responsible for the wide clinical spectrum of COVID-19 remain still incompletely understood [ 1 , 2 ]. Although the natural …

14.10.2020 | Original Paper

Tubulin carboxypeptidase activity of vasohibin-1 inhibits angiogenesis by interfering with endocytosis and trafficking of pro-angiogenic factor receptors

Receptor endocytosis is crucial for integrating extracellular stimuli of pro-angiogenic factors, including vascular endothelial growth factor (VEGF), into the cell via signal transduction. VEGF not only triggers various angiogenic events including …

14.10.2020 | COVID-19 | Letter Open Access

Angiogenesis, hereditary hemorrhagic telangiectasia and COVID-19

Hereditary hemorrhagic telangiectasia (HHT) is a rare autosomal-dominant disease characterized by pathologic angiogenesis that provokes vascular overgrowth. The evidence about the influence of Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) …

10.10.2020 | Short Communication Open Access

3D analysis of microvasculature in murine liver fibrosis models using synchrotron radiation-based microtomography

Cirrhosis describes the development of excess fibrous tissue around regenerative nodules in response to chronic liver injury and usually leads to irreversible organ damage and end-stage liver disease. During the development of cirrhosis, the …

09.10.2020 | Letter

Vessel tech: a high-accuracy pipeline for comprehensive mouse retinal vasculature characterization

Mouse retinal vasculature is a well-recognized and commonly used animal model for angiogenesis and microvascular remodeling. Morphological features of retinal vasculature reflect the vessel’s biological functions, and are critical in understanding …

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Angiogenesis is an international peer-reviewed journal devoted to the publication of top quality original articles and reviews on the cellular and molecular mechanisms that regulate angiogenesis in physiological and pathological conditions. As a central source for rapid communications representing the full spectrum of angiogenesis research, this multidisciplinary journal publishes innovative experimental studies using molecular, in vitro, animal model systems and clinical investigations of angiogenic diseases. Angiogenesis also reports on novel therapeutic approaches for promoting or inhibiting angiogenesis as well as new markers and techniques for disease diagnosis and prognosis.

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