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Pediatric Nephrology

Erschienen in:

01.04.2014 | Review

Bone morphogenetic protein signaling in nephron progenitor cells

verfasst von: Leif Oxburgh, Aaron C. Brown, Sree Deepthi Muthukrishnan, Jennifer L. Fetting

Erschienen in: Pediatric Nephrology | Ausgabe 4/2014

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Abstract

Bone morphogenetic protein (BMP) signaling plays an essential role in many aspects of kidney development, and is a major determinant of outcome in kidney injury. BMP treatment is also an essential component of protocols for differentiation of nephron progenitors from pluripotent stem cells. This review discusses the role of BMP signaling to nephron progenitor cells in each of these contexts.

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Titel: Bone morphogenetic protein signaling in nephron progenitor cells
verfasst von: Leif Oxburgh
Aaron C. Brown
Sree Deepthi Muthukrishnan
Jennifer L. Fetting
Publikationsdatum: 01.04.2014
Verlag: Springer Berlin Heidelberg
Erschienen in: Pediatric Nephrology / Ausgabe 4/2014
Print ISSN: 0931-041X
Elektronische ISSN: 1432-198X
DOI: https://doi.org/10.1007/s00467-013-2589-2

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Bone morphogenetic protein signaling in nephron progenitor cells

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