Ausgabe 1/2022
Inhalt (101 Artikel)
Circular RNA circCCDC85A inhibits breast cancer progression via acting as a miR-550a-5p sponge to enhance MOB1A expression
Lingjiao Meng, Sheng Chang, Yang Sang, Pingan Ding, Liuxin Wang, Xixi Nan, Ruiyu Xu, Fei Liu, Lina Gu, Yang Zheng, Ziyi Li, Meixiang Sang
Common variants in breast cancer risk loci predispose to distinct tumor subtypes
Thomas U. Ahearn, Haoyu Zhang, Kyriaki Michailidou, Roger L. Milne, Manjeet K. Bolla, Joe Dennis, Alison M. Dunning, Michael Lush, Qin Wang, Irene L. Andrulis, Hoda Anton-Culver, Volker Arndt, Kristan J. Aronson, Paul L. Auer, Annelie Augustinsson, Adinda Baten, Heiko Becher, Sabine Behrens, Javier Benitez, Marina Bermisheva, Carl Blomqvist, Stig E. Bojesen, Bernardo Bonanni, Anne-Lise Børresen-Dale, Hiltrud Brauch, Hermann Brenner, Angela Brooks-Wilson, Thomas Brüning, Barbara Burwinkel, Saundra S. Buys, Federico Canzian, Jose E. Castelao, Jenny Chang-Claude, Stephen J. Chanock, Georgia Chenevix-Trench, Christine L. Clarke, Kristine K. Sahlberg, Lars Ottestad, Rolf Kåresen, Ellen Schlichting, Marit Muri Holmen, Toril Sauer, Vilde Haakensen, Olav Engebråten, Bjørn Naume, Alexander Fosså, Cecile E. Kiserud, Kristin V. Reinertsen, Åslaug Helland, Margit Riis, Jürgen Geisler, J. Margriet Collée, Angela Cox, Simon S. Cross, Kamila Czene, Mary B. Daly, Peter Devilee, Thilo Dörk, Miriam Dwek, Diana M. Eccles, D. Gareth Evans, Peter A. Fasching, Jonine Figueroa, Giuseppe Floris, Manuela Gago-Dominguez, Susan M. Gapstur, José A. García-Sáenz, Mia M. Gaudet, Graham G. Giles, Mark S. Goldberg, Anna González-Neira, Grethe I. Grenaker Alnæs, Mervi Grip, Pascal Guénel, Christopher A. Haiman, Per Hall, Ute Hamann, Elaine F. Harkness, Bernadette A. M. Heemskerk-Gerritsen, Bernd Holleczek, Antoinette Hollestelle, Maartje J. Hooning, Robert N. Hoover, John L. Hopper, Anthony Howell, Christine Clarke, Rosemary Balleine, Robert Baxter, Stephen Braye, Jane Carpenter, Jane Dahlstrom, John Forbes, CSoon Lee, Deborah Marsh, Adrienne Morey, Nirmala Pathmanathan, Rodney Scott, Peter Simpson, Allan Spigelman, Nicholas Wilcken, Desmond Yip, Nikolajs Zeps, Stephen Fox, Ian Campbell, David Bowtell, Georgia Chenevix-Trench, Amanda Spurdle, Penny Webb, Anna de Fazio, Margaret Tassell, Judy Kirk, Geoff Lindeman, Melanie Price, Melissa Southey, Roger Milne, Sid Deb, Milena Jakimovska, Anna Jakubowska, Esther M. John, Michael E. Jones, Audrey Jung, Rudolf Kaaks, Saila Kauppila, Renske Keeman, Elza Khusnutdinova, Cari M. Kitahara, Yon-Dschun Ko, Stella Koutros, Vessela N. Kristensen, Ute Krüger, Katerina Kubelka-Sabit, Allison W. Kurian, Kyriacos Kyriacou, Diether Lambrechts, Derrick G. Lee, Annika Lindblom, Martha Linet, Jolanta Lissowska, Ana Llaneza, Wing-Yee Lo, Robert J. MacInnis, Arto Mannermaa, Mehdi Manoochehri, Sara Margolin, Maria Elena Martinez, Catriona McLean, Alfons Meindl, Usha Menon, Heli Nevanlinna, William G. Newman, Jesse Nodora, Kenneth Offit, Håkan Olsson, Nick Orr, Tjoung-Won Park-Simon, Alpa V. Patel, Julian Peto, Guillermo Pita, Dijana Plaseska-Karanfilska, Ross Prentice, Kevin Punie, Katri Pylkäs, Paolo Radice, Gad Rennert, Atocha Romero, Thomas Rüdiger, Emmanouil Saloustros, Sarah Sampson, Dale P. Sandler, Elinor J. Sawyer, Rita K. Schmutzler, Minouk J. Schoemaker, Ben Schöttker, Mark E. Sherman, Xiao-Ou Shu, Snezhana Smichkoska, Melissa C. Southey, John J. Spinelli, Anthony J. Swerdlow, Rulla M. Tamimi, William J. Tapper, Jack A. Taylor, Lauren R. Teras, Mary Beth Terry, Diana Torres, Melissa A. Troester, Celine M. Vachon, Carolien H. M. van Deurzen, Elke M. van Veen, Philippe Wagner, Clarice R. Weinberg, Camilla Wendt, Jelle Wesseling, Robert Winqvist, Alicja Wolk, Xiaohong R. Yang, Wei Zheng, Fergus J. Couch, Jacques Simard, Peter Kraft, Douglas F. Easton, Paul D. P. Pharoah, Marjanka K. Schmidt, Montserrat García-Closas, Nilanjan Chatterjee
Sugar-sweetened beverage consumption and breast composition in a longitudinal study of Chilean girls
Lara Yoon, Camila Corvalán, Ana Pereira, John Shepherd, Karin B. Michels
Incidence of breast cancer subtypes in immigrant and non-immigrant women in Norway
Kirsti V. Hjerkind, Anna L. V. Johansson, Cassia B. Trewin, Hege G. Russnes, Giske Ursin
The impact of breast density notification on rescreening rates within a population-based mammographic screening program
Sarah Pirikahu, Helen Lund, Gemma Cadby, Elizabeth Wylie, Jennifer Stone
LncRNA IPW inhibits growth of ductal carcinoma in situ by downregulating ID2 through miR-29c
Ravindra Pramod Deshpande, Sambad Sharma, Yin Liu, Puspa Raj Pandey, Xinhong Pei, Kerui Wu, Shih-Ying Wu, Abhishek Tyagi, Dan Zhao, Yin-Yuan Mo, Kounosuke Watabe
KRT13 promotes stemness and drives metastasis in breast cancer through a plakoglobin/c-Myc signaling pathway
Lijuan Yin, Qinlong Li, Stefan Mrdenovic, Gina Chia-Yi Chu, Boyang Jason Wu, Hong Bu, Peng Duan, Jayoung Kim, Sungyong You, Michael S. Lewis, Gangning Liang, Ruoxiang Wang, Haiyen E. Zhau, Leland W. K. Chung
Neuropilin-1 is over-expressed in claudin-low breast cancer and promotes tumor progression through acquisition of stem cell characteristics and RAS/MAPK pathway activation
Yu Hin Tang, Anja Rockstroh, Kamil A. Sokolowski, Layla-Rose Lynam, Melanie Lehman, Erik W. Thompson, Philip A. Gregory, Colleen C. Nelson, Marianna Volpert, Brett G. Hollier
Measured body size and serum estrogen metabolism in postmenopausal women: the Ghana Breast Health Study
Ashley M. Geczik, Roni T. Falk, Xia Xu, Daniel Ansong, Joel Yarney, Beatrice Wiafe-Addai, Lawrence Edusei, Florence Dedey, Verna Vanderpuye, Nicholas Titiloye, Ernest Adjei, Francis Aitpillah, Ernest Osei-Bonsu, Joseph Oppong, Richard Biritwum, Kofi Nyarko, Seth Wiafe, Baffour Awuah, Joe-Nat Clegg-Lamptey, Thomas U. Ahearn, Jonine Figueroa, Montserrat Garcia-Closas, Louise A. Brinton, Britton Trabert
Gene expression predicts dormant metastatic breast cancer cell phenotype
Qihao Ren, Weng Hua Khoo, Alexander P. Corr, Tri Giang Phan, Peter I. Croucher, Sheila A. Stewart
Unique ER PR expression pattern in breast cancers with CHEK2 mutation: a hormone receptor and HER2 analysis based on germline cancer predisposition genes
Grace Wei, Mingxiang Teng, Marilin Rosa, Xia Wang
Associations of genetically proxied inhibition of HMG-CoA reductase, NPC1L1, and PCSK9 with breast cancer and prostate cancer
Lulu Sun, Huan Ding, Yiming Jia, Mengyao Shi, Daoxia Guo, Pinni Yang, Yu Wang, Fanghua Liu, Yonghong Zhang, Zhengbao Zhu
Microtubule disruption reduces metastasis more effectively than primary tumor growth
Keyata N. Thompson, Julia A. Ju, Eleanor C. Ory, Stephen J. P. Pratt, Rachel M. Lee, Trevor J. Mathias, Katarina T. Chang, Cornell J. Lee, Olga G. Goloubeva, Patrick C. Bailey, Kristi R. Chakrabarti, Christopher M. Jewell, Michele I. Vitolo, Stuart S. Martin
Artificial intelligence in mammographic phenotyping of breast cancer risk: a narrative review
Aimilia Gastounioti, Shyam Desai, Vinayak S. Ahluwalia, Emily F. Conant, Despina Kontos
Assessing lead time bias due to mammography screening on estimates of loss in life expectancy
Elisavet Syriopoulou, Alessandro Gasparini, Keith Humphreys, Therese M.-L. Andersson
Hybrid high-definition microvessel imaging/shear wave elastography improves breast lesion characterization
Juanjuan Gu, Redouane Ternifi, Nicholas B. Larson, Jodi M. Carter, Judy C. Boughey, Daniela L. Stan, Robert T. Fazzio, Mostafa Fatemi, Azra Alizad
Cellular mechanisms underlying response and resistance to CDK4/6 inhibitors in the treatment of hormone receptor-positive breast cancer
April C. Watt, Shom Goel
INHBA is a mediator of aggressive tumor behavior in HER2+ basal breast cancer
Moqing Liu, Rebecca Smith, Tiera Liby, Kami Chiotti, Claudia S. López, James E. Korkola
Selective pressure of endocrine therapy activates the integrated stress response through NFκB signaling in a subpopulation of ER positive breast cancer cells
Svetlana E. Semina, Purab Pal, Nidhi S. Kansara, Rosemary J. Huggins, Elaine T. Alarid, Geoffrey L. Greene, Jonna Frasor
Radiomics predicts the prognosis of patients with locally advanced breast cancer by reflecting the heterogeneity of tumor cells and the tumor microenvironment
Xuanyi Wang, Tiansong Xie, Jurui Luo, Zhengrong Zhou, Xiaoli Yu, Xiaomao Guo
Quantitative glycoproteomics analysis identifies novel FUT8 targets and signaling networks critical for breast cancer cell invasiveness
Cheng-Fen Tu, Fu-An Li, Ling-Hui Li, Ruey-Bing Yang
Clinical significance of HER2-low expression in early breast cancer: a nationwide study from the Korean Breast Cancer Society
Hye Sung Won, Juneyoung Ahn, Yongseon Kim, Jin Sung Kim, Jeong-Yoon Song, Hong-Kyu Kim, Jeeyeon Lee, Heung Kyu Park, Yong-Seok Kim
Targeting SHP2 phosphatase in breast cancer overcomes RTK-mediated resistance to PI3K inhibitors
Guus J. J. E. Heynen, Kamil Lisek, Regina Vogel, Annika Wulf-Goldenberg, Joshua Alcaniz, Elodie Montaudon, Elisabetta Marangoni, Walter Birchmeier
Population-based estimates of age-specific cumulative risk of breast cancer for pathogenic variants in ATM
Anne-Laure Renault, James G. Dowty, Jason A. Steen, Shuai Li, Ingrid M. Winship, Graham G. Giles, John L. Hopper, Melissa C. Southey, Tú Nguyen-Dumont
Breast cancer metastasis to brain results in recruitment and activation of microglia through annexin-A1/formyl peptide receptor signaling
Sok Lin Foo, Karishma Sachaphibulkij, Corinne L. Y. Lee, Gracemary L. R. Yap, Jianzhou Cui, Thiruma Arumugam, Lina H. K. Lim
SETDB1 interactions with PELP1 contributes to breast cancer endocrine therapy resistance
Zexuan Liu, Junhao Liu, Behnam Ebrahimi, Uday P. Pratap, Yi He, Kristin A. Altwegg, Weiwei Tang, Xiaonan Li, Zhao Lai, Yidong Chen, Liangfang Shen, Gangadhara R. Sareddy, Suryavathi Viswanadhapalli, Rajeshwar R. Tekmal, Manjeet K. Rao, Ratna K. Vadlamudi
Genome-wide and transcriptome-wide association studies of mammographic density phenotypes reveal novel loci
Hongjie Chen, Shaoqi Fan, Jennifer Stone, Deborah J. Thompson, Julie Douglas, Shuai Li, Christopher Scott, Manjeet K. Bolla, Qin Wang, Joe Dennis, Kyriaki Michailidou, Christopher Li, Ulrike Peters, John L. Hopper, Melissa C. Southey, Tu Nguyen-Dumont, Tuong L. Nguyen, Peter A. Fasching, Annika Behrens, Gemma Cadby, Rachel A. Murphy, Kristan Aronson, Anthony Howell, Susan Astley, Fergus Couch, Janet Olson, Roger L. Milne, Graham G. Giles, Christopher A. Haiman, Gertraud Maskarinec, Stacey Winham, Esther M. John, Allison Kurian, Heather Eliassen, Irene Andrulis, D. Gareth Evans, William G. Newman, Per Hall, Kamila Czene, Anthony Swerdlow, Michael Jones, Marina Pollan, Pablo Fernandez-Navarro, Daniel S. McConnell, Vessela N. Kristensen, Joseph H. Rothstein, Pei Wang, Laurel A. Habel, Weiva Sieh, Alison M. Dunning, Paul D. P. Pharoah, Douglas F. Easton, Gretchen L. Gierach, Rulla M. Tamimi, Celine M. Vachon, Sara Lindström
Hormone and receptor activator of NF-κB (RANK) pathway gene expression in plasma and mammographic breast density in postmenopausal women
Rachel Mintz, Mei Wang, Shuai Xu, Graham A. Colditz, Chris Markovic, Adetunji T. Toriola
Infertility and risk of breast cancer in men: a national case–control study in England and Wales
Anthony J. Swerdlow, Cydney Bruce, Rosie Cooke, Penny Coulson, Michael E. Jones
PTHrP induces STAT5 activation, secretory differentiation and accelerates mammary tumor development
Diego Y. Grinman, Kata Boras-Granic, Farzin M. Takyar, Pamela Dann, Julie R. Hens, Christina Marmol, Jongwon Lee, Jungmin Choi, Lewis A. Chodosh, Martin E. Garcia Sola, John J. Wysolmerski
Activation of the viral sensor oligoadenylate synthetase 2 (Oas2) prevents pregnancy-driven mammary cancer metastases
Wing-Hong Jonathan Ho, Andrew M. K. Law, Etienne Masle-Farquhar, Lesley E. Castillo, Amanda Mawson, Moira K. O’Bryan, Christopher C. Goodnow, David Gallego-Ortega, Samantha R. Oakes, Christopher J. Ormandy
Biological interpretation of prognostic radiomic score by correlating with tumor heterogeneity and microenvironment
Jieling Zheng, Bin Zhang
Beta 2 adrenergic receptor and mu opioid receptor interact to potentiate the aggressiveness of human breast cancer cell by activating the glycogen synthase kinase 3 signaling
Bénédicte Rousseau, Sengottuvelan Murugan, Ajay Palagani, Dipak K. Sarkar
Radiogenomic analysis of primary breast cancer reveals [18F]-fluorodeoxglucose dynamic flux-constants are positively associated with immune pathways and outperform static uptake measures in associating with glucose metabolism
G. P. Ralli, R. D. Carter, D. R. McGowan, W.-C. Cheng, D. Liu, E. J. Teoh, N. Patel, F. Gleeson, A. L. Harris, S. R. Lord, F. M. Buffa, J. D. Fenwick
CCR5 activation and endocytosis in circulating tumor-derived cells isolated from the blood of breast cancer patients provide information about clinical outcome
Ashvathi Raghavakaimal, Massimo Cristofanilli, Cha-Mei Tang, R. K. Alpaugh, Kirby P. Gardner, Saranya Chumsri, Daniel L. Adams
Effect of physical exercise on cognitive function after chemotherapy in patients with breast cancer: a randomized controlled trial (PAM study)
E. W. Koevoets, S. B. Schagen, M. B. de Ruiter, M. I. Geerlings, L. Witlox, E. van der Wall, M. M. Stuiver, G. S. Sonke, M. J. Velthuis, J. J. Jobsen, M. B. E. Menke-Pluijmers, E. Göker, C. C. van der Pol, M. E. M. M. Bos, L. W. Tick, N. A. van Holsteijn, J. van der Palen, A. M. May, E. M. Monninkhof, Annebeth W. Haringhuizen, Wim A. van der Steeg, Dirkje W. Sommeijer, Frederiek Terheggen, Charlotte Blanken-Peeters, Harold Fliervoet, Margrethe S. Schlooz-Vries, Tanja G. Frakking, Marc W. A. van Tilburg, Corina Oldenhuis, Maartje F. Sier
Racial disparities in triple negative breast cancer: toward a causal architecture approach
Scott D. Siegel, Madeline M. Brooks, Shannon M. Lynch, Jennifer Sims-Mourtada, Zachary T. Schug, Frank C. Curriero
Hypoxia-regulated carbonic anhydrase IX (CAIX) protein is an independent prognostic indicator in triple negative breast cancer
Chong Hui Clara Ong, Dong Yeul Lee, Bernett Lee, Huihua Li, Jeffrey Chun Tatt Lim, Johnathan Xiande Lim, Joe Poh Sheng Yeong, Hiu Yeung Lau, Aye Aye Thike, Puay Hoon Tan, Jabed Iqbal
Inducible localized delivery of an anti-PD-1 scFv enhances anti-tumor activity of ROR1 CAR-T cells in TNBC
Micaela Harrasser, Satyen Harish Gohil, Hiu Lau, Marco Della Peruta, Vincent Muczynski, Dominic Patel, Elena Miranda, Kristiana Grigoriadis, Anita Grigoriadis, David Granger, Rachel Evans, Amit Chunilal Nathwani
Multiple roles for Bcl-3 in mammary gland branching, stromal collagen invasion, involution and tumor pathology
David Carr, Aiman Zein, Josée Coulombe, Tianqi Jiang, Miguel A. Cabrita, Gwendoline Ward, Manijeh Daneshmand, Andrea Sau, M. A. Christine Pratt
Combined inhibition of EZH2 and ATM is synthetic lethal in BRCA1-deficient breast cancer
Leonie Ratz, Chiara Brambillasca, Leandra Bartke, Maxim A. Huetzen, Jonas Goergens, Orsolya Leidecker, Ron D. Jachimowicz, Marieke van de Ven, Natalie Proost, Bjørn Siteur, Renske de Korte-Grimmerink, Peter Bouwman, Emilia M. Pulver, Roebi de Bruijn, Jörg Isensee, Tim Hucho, Gaurav Pandey, Maarten van Lohuizen, Peter Mallmann, Hans Christian Reinhardt, Jos Jonkers, Julian Puppe
Preventing ovariectomy-induced weight gain decreases tumor burden in rodent models of obesity and postmenopausal breast cancer
Elizabeth A. Wellberg, Karen A. Corleto, L. Allyson Checkley, Sonali Jindal, Ginger Johnson, Janine A. Higgins, Sarina Obeid, Steven M. Anderson, Ann D. Thor, Pepper J. Schedin, Paul S. MacLean, Erin D. Giles
DNA methylation changes in response to neoadjuvant chemotherapy are associated with breast cancer survival
Christine Aaserød Pedersen, Maria Dung Cao, Thomas Fleischer, Morten B. Rye, Stian Knappskog, Hans Petter Eikesdal, Per Eystein Lønning, Jörg Tost, Vessela N. Kristensen, May-Britt Tessem, Guro F. Giskeødegård, Tone F. Bathen
Know thy cells: commonly used triple-negative human breast cancer cell lines carry mutations in RAS and effectors
Kay-Uwe Wagner
Towards defining morphologic parameters of normal parous and nulliparous breast tissues by artificial intelligence
Joshua Ogony, Thomas de Bel, Derek C. Radisky, Jennifer Kachergus, E. Aubrey Thompson, Amy C. Degnim, Kathryn J. Ruddy, Tracy Hilton, Melody Stallings-Mann, Celine Vachon, Tanya L. Hoskin, Michael G. Heckman, Robert A. Vierkant, Launia J. White, Raymond M. Moore, Jodi Carter, Matthew Jensen, Laura Pacheco-Spann, Jill E. Henry, Anna Maria Storniolo, Stacey J. Winham, Jeroen van der Laak, Mark E. Sherman
High AUF1 level in stromal fibroblasts promotes carcinogenesis and chemoresistance and predicts unfavorable prognosis among locally advanced breast cancer patients
Taher Al-Tweigeri, Noura N. AlRaouji, Asma Tulbah, Maria Arafah, Mouad Aboussekhra, Falah Al-Mohanna, Ahmed Mostafa Gad, Abdelmonneim M. Eldali, Tusneem A. Elhassan, Abdelilah Aboussekhra
Exposure to polycyclic aromatic hydrocarbons during pregnancy and breast tissue composition in adolescent daughters and their mothers: a prospective cohort study
Rebecca D. Kehm, E. Jane Walter, Sabine Oskar, Melissa L. White, Parisa Tehranifar, Julie B. Herbstman, Frederica Perera, Lothar Lilge, Rachel L. Miller, Mary Beth Terry
Upregulation of Nox4 induces a pro-survival Nrf2 response in cancer-associated fibroblasts that promotes tumorigenesis and metastasis, in part via Birc5 induction
Shakeel Mir, Briana D. Ormsbee Golden, Brandon J. Griess, Raghupathy Vengoji, Eric Tom, Elizabeth A. Kosmacek, Rebecca E. Oberley-Deegan, Geoffrey A. Talmon, Vimla Band, Melissa LT. Teoh-Fitzgerald
The association of age at menarche and adult height with mammographic density in the International Consortium of Mammographic Density
Sarah V. Ward, Anya Burton, Rulla M. Tamimi, Ana Pereira, Maria Luisa Garmendia, Marina Pollan, Norman Boyd, Isabel dos-Santos-Silva, Gertraud Maskarinec, Beatriz Perez-Gomez, Celine Vachon, Hui Miao, Martín Lajous, Ruy López-Ridaura, Kimberly Bertrand, Ava Kwong, Giske Ursin, Eunjung Lee, Huiyan Ma, Sarah Vinnicombe, Sue Moss, Steve Allen, Rose Ndumia, Sudhir Vinayak, Soo-Hwang Teo, Shivaani Mariapun, Beata Peplonska, Agnieszka Bukowska-Damska, Chisato Nagata, John Hopper, Graham Giles, Vahit Ozmen, Mustafa Erkin Aribal, Joachim Schüz, Carla H. Van Gils, Johanna O. P. Wanders, Reza Sirous, Mehri Sirous, John Hipwell, Jisun Kim, Jong Won Lee, Caroline Dickens, Mikael Hartman, Kee-Seng Chia, Christopher Scott, Anna M. Chiarelli, Linda Linton, Anath Arzee Flugelman, Dorria Salem, Rasha Kamal, Valerie McCormack, Jennifer Stone
Correction to: Clinical implications of prospective genomic profiling of metastatic breast cancer patients
Courtney T. van Geelen, Peter Savas, Zhi Ling Teo, Stephen J. Luen, Chen-Fang Weng, Yi-An Ko, Keilly S. Kuykhoven, Franco Caramia, Roberto Salgado, Prudence A. Francis, Sarah-Jane Dawson, Stephen B. Fox, Andrew Fellowes, Sherene Loi
Combined Dusp4 and p53 loss with Dbf4 amplification drives tumorigenesis via cell cycle restriction and replication stress escape in breast cancer
Ann Hanna, Mellissa J. Nixon, M. Valeria Estrada, Violeta Sanchez, Quanhu Sheng, Susan R. Opalenik, Abigail L. Toren, Joshua Bauer, Phillip Owens, Frank M. Mason, Rebecca S. Cook, Melinda E. Sanders, Carlos L. Arteaga, Justin M. Balko
Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer
Annamaria Salvati, Viola Melone, Assunta Sellitto, Francesca Rizzo, Roberta Tarallo, Tuula A. Nyman, Giorgio Giurato, Giovanni Nassa, Alessandro Weisz
Correction to: Circulating microRNAs in the early prediction of disease recurrence in primary breast cancer
Chara Papadaki, Michalis Stratigos, Georgios Markakis, Maria Spiliotaki, Georgios Mastrostamatis, Christoforos Nikolaou, Dimitrios Mavroudis, Sofia Agelaki
Chromatin accessibility landscape and active transcription factors in primary human invasive lobular and ductal breast carcinomas
Sanghoon Lee, Hatice Ulku Osmanbeyoglu
Evaluating the effectiveness of abbreviated breast MRI (abMRI) interpretation training for mammogram readers: a multi-centre study assessing diagnostic performance, using an enriched dataset
Lyn I. Jones, Andrea Marshall, Premkumar Elangovan, Rebecca Geach, Sadie McKeown-Keegan, Sarah Vinnicombe, Sam A. Harding, Sian Taylor-Phillips, Mark Halling-Brown, Christopher Foy, Elizabeth O’Flynn, Hesam Ghiasvand, Claire Hulme, Janet A. Dunn, Christiane Kuhl, Jennifer Wookey, Janice Rose, Victoria Taylor, John Gifford, Rosie Gray, Thomas William-Jones, Karen Litton, Simon Lloyd, Jim Steel, Elisabeth Kutt, Alexandra Valencia, Alice Pocklington, Anjum Mahatma, Helen Massey, Gillian Clark, Clare McLachlan, Gemini Beckett, Clare Alison, Miklos Barta, Claudia Betancourt, Julie Bramwell, Nichola Bright, Helen Burt, Louise Cann, Jane Ceney, Eleanor Cornford, Diana Dalgliesh, Sarah Doyle, Sarah Fearn, Dagmar Godden, Zoe Goldthorpe, Lucinda Hobson, Paul Hynam, Emma Jackson, Margaret Jenkin, Beckie Kingsnorth, Katherine Klimczak, Alice Moody, Sarah Perrin, Alison Peters, Elizabeth Preston, Anne Ratsey, Richard Sidebottom, Lesley Stephenson, Michelle Taylor, Erika Toth, Frances Vincent, Sharon Watkin, Sue Widdison, Jennifer Williams, Karen Wilmot, Sravya Singamaneni, Zsolt Friedrich, Joanne Robson, Elizabeth Cullimore, Anna Mankelow
Racial disparities in breast cancer preclinical and clinical models
Shannique Clarke, Sheray N. Chin, Leah Dodds, Sophia H. L. George, Simone Badal
Evaluation of tumour heterogeneity by 18F-fluoroestradiol PET as a predictive measure in breast cancer patients receiving palbociclib combined with endocrine treatment
Cheng Liu, Shihui Hu, Xiaoping Xu, Yongping Zhang, Biyun Wang, Shaoli Song, Zhongyi Yang
Impact of stromal tumor-infiltrating lymphocytes (sTILs) on response to neoadjuvant chemotherapy in triple-negative early breast cancer in the WSG-ADAPT TN trial
Cornelia Kolberg-Liedtke, Friedrich Feuerhake, Madlen Garke, Matthias Christgen, Ronald Kates, Eva Maria Grischke, Helmut Forstbauer, Michael Braun, Mathias Warm, John Hackmann, Christoph Uleer, Bahriye Aktas, Claudia Schumacher, Sherko Kuemmel, Rachel Wuerstlein, Monika Graeser, Ulrike Nitz, Hans Kreipe, Oleg Gluz, Nadia Harbeck
Methylation-based markers of aging and lifestyle-related factors and risk of breast cancer: a pooled analysis of four prospective studies
Pierre-Antoine Dugué, Clara Bodelon, Felicia F. Chung, Hannah R. Brewer, Srikant Ambatipudi, Joshua N. Sampson, Cyrille Cuenin, Veronique Chajès, Isabelle Romieu, Giovanni Fiorito, Carlotta Sacerdote, Vittorio Krogh, Salvatore Panico, Rosario Tumino, Paolo Vineis, Silvia Polidoro, Laura Baglietto, Dallas English, Gianluca Severi, Graham G. Giles, Roger L. Milne, Zdenko Herceg, Montserrat Garcia-Closas, James M. Flanagan, Melissa C. Southey
Exosomal Wnt7a from a low metastatic subclone promotes lung metastasis of a highly metastatic subclone in the murine 4t1 breast cancer
Chunning Li, Teizo Yoshimura, Miao Tian, Yuze Wang, Takamasa Kondo, Ken-Ichi Yamamoto, Masayoshi Fujisawa, Toshiaki Ohara, Masakiyo Sakaguchi, Akihiro Matsukawa
Relationship between ER expression by IHC or mRNA with Ki67 response to aromatase inhibition: a POETIC study
Elena Lopez-Knowles, Simone Detre, Margaret Hills, Eugene F. Schuster, Maggie C. U. Cheang, Holly Tovey, Lucy S. Kilburn, Judith M. Bliss, John Robertson, Elizabeth Mallon, Anthony Skene, Abigail Evans, Ian Smith, Mitch Dowsett
MiRNA expression deregulation correlates with the Oncotype DX® DCIS score
Olivier Loudig, Megan I. Mitchell, Iddo Z. Ben-Dov, Christina Liu, Susan Fineberg
Deep whole genome sequencing identifies recurrent genomic alterations in commonly used breast cancer cell lines and patient-derived xenograft models
Niantao Deng, Andre Minoche, Kate Harvey, Meng Li, Juliane Winkler, Andrei Goga, Alex Swarbrick
Breast cancer risk in papilloma patients: Osteopontin splice variants indicate prognosis
Piotr Ziółkowski, Marta Woźniak, Ahmad Mansour, Yu An, Georg F. Weber
Krüppel-like factor 7 influences translation and pathways involved in ribosomal biogenesis in breast cancer
Anne-Marie Lüchtenborg, Patrick Metzger, Miguel Cosenza Contreras, Victor Oria, Martin L. Biniossek, Franziska Lindner, Klemens Fröhlich, Ambrus Malyi, Thalia Erbes, Nicole Gensch, Jochen Maurer, Andreas Thomsen, Melanie Boerries, Oliver Schilling, Martin Werner, Peter Bronsert
Sex steroid hormones and risk of breast cancer: a two-sample Mendelian randomization study
Aayah Nounu, Siddhartha P. Kar, Caroline L. Relton, Rebecca C. Richmond
High platelet-to-lymphocyte ratios in triple-negative breast cancer associates with immunosuppressive status of TILs
Hiroko Onagi, Yoshiya Horimoto, Asumi Sakaguchi, Daiki Ikarashi, Naotake Yanagisawa, Takayuki Nakayama, Tetsuya Nakatsura, Yumiko Ishizuka, Ritsuko Sasaki, Junichiro Watanabe, Mitsue Saito, Harumi Saeki, Takuo Hayashi, Atsushi Arakawa, Takashi Yao, Shigehisa Kitano
Elevated NRAS expression during DCIS is a potential driver for progression to basal-like properties and local invasiveness
Ze-Yi Zheng, Hanan Elsarraj, Jonathan T. Lei, Yan Hong, Meenakshi Anurag, Long Feng, Hilda Kennedy, Yichao Shen, Flora Lo, Zifan Zhao, Bing Zhang, Xiang H.-F. Zhang, Ossama W. Tawfik, Fariba Behbod, Eric C. Chang
PredictCBC-2.0: a contralateral breast cancer risk prediction model developed and validated in ~ 200,000 patients
Daniele Giardiello, Maartje J. Hooning, Michael Hauptmann, Renske Keeman, B. A. M. Heemskerk-Gerritsen, Heiko Becher, Carl Blomqvist, Stig E. Bojesen, Manjeet K. Bolla, Nicola J. Camp, Kamila Czene, Peter Devilee, Diana M. Eccles, Peter A. Fasching, Jonine D. Figueroa, Henrik Flyger, Montserrat García-Closas, Christopher A. Haiman, Ute Hamann, John L. Hopper, Anna Jakubowska, Floor E. Leeuwen, Annika Lindblom, Jan Lubiński, Sara Margolin, Maria Elena Martinez, Heli Nevanlinna, Ines Nevelsteen, Saskia Pelders, Paul D. P. Pharoah, Sabine Siesling, Melissa C. Southey, Annemieke H. van der Hout, Liselotte P. van Hest, Jenny Chang-Claude, Per Hall, Douglas F. Easton, Ewout W. Steyerberg, Marjanka K. Schmidt
Matrix Gla protein (MGP), GATA3, and TRPS1: a novel diagnostic panel to determine breast origin
Tian Du, Lu Pan, Chengyou Zheng, Keming Chen, Yuanzhong Yang, Jiewei Chen, Xue Chao, Mei Li, Jiabin Lu, Rongzhen Luo, Jinhui Zhang, Yu Wu, Jiehua He, Dongping Jiang, Peng Sun
Tolerability of Eribulin and correlation between polymorphisms and neuropathy in an unselected population of female patients with metastatic breast cancer: results of the multicenter, single arm, phase IV PAINTER study
Nicla La Verde, Giovanna Damia, Ornella Garrone, Daniele Santini, Alessandra Fabi, Mariangela Ciccarese, Daniele Giulio Generali, Martina Nunzi, Elena Poletto, Elisa Ferraris, Elisabetta Cretella, Giuseppa Scandurra, Icro Meattini, Alessandro Stefano Bertolini, Luigi Cavanna, Elena Collovà, Emanuela Romagnoli, Eliana Rulli, Lorenzo Legramandi, Federica Guffanti, Annalisa Bramati, Anna Moretti, Alessandra Cassano, Patrizia Vici, Valter Torri, Gabriella Farina
RAB4A GTPase regulates epithelial-to-mesenchymal transition by modulating RAC1 activation
Subbulakshmi Karthikeyan, Patrick J. Casey, Mei Wang
Steroid receptor coactivator-3 inhibition generates breast cancer antitumor immune microenvironment
Sang Jun Han, Nuri Sung, Jin Wang, Bert W. O’Malley, David M. Lonard
Population-based estimate for the correlation of the Oncotype Dx Breast Recurrence Score® result and Ki-67 IHC MIB-1 pharmDx in HR+, HER2−, node-positive early breast cancer
Michael Crager, Sameera R. Wijayawardana, Aaron M. Gruver, Andrea Blacklock, Christy Russell, Frederick L. Baehner, Francisco Sapunar
Loss of Brca1 and Trp53 in adult mouse mammary ductal epithelium results in development of hormone receptor-positive or hormone receptor-negative tumors, depending on inactivation of Rb family proteins
Ludmila Szabova, Melanie B. Gordon, Lucy Lu, Nathan Pate, Laura Bassel, Anthony J. Iacovelli, Baktiar Karim, Philip J. Homan, Deborah B. Householder, Theresa M. Guerin, Sandra Burkett, Amanda M. Day, Wendi Custer, Zoe Weaver Ohler
A genome-wide association study of mammographic texture variation
Yuxi Liu, Hongjie Chen, John Heine, Sara Lindstrom, Constance Turman, Erica T. Warner, Stacey J. Winham, Celine M. Vachon, Rulla M. Tamimi, Peter Kraft, Xia Jiang
Birthweight, childhood body size, and timing of puberty and risks of breast cancer by menopausal status and tumor receptor subtypes
Dorthe C. Pedersen, Britt W. Jensen, Anne Tjønneland, Zorana J. Andersen, Lene Mellemkjaer, Lise G. Bjerregaard, Julie Aarestrup, Jennifer L. Baker
Association of body mass index and inflammatory dietary pattern with breast cancer pathologic and genomic immunophenotype in the nurses’ health study
Sarah Asad, Adrienne Damicis, Yujing J. Heng, Kathryn Kananen, Katharine A. Collier, Elizabeth J. Adams, Kevin H. Kensler, Gabrielle M. Baker, Robert Wesolowski, Sagar Sardesai, Margaret Gatti-Mays, Bhuvaneswari Ramaswamy, A. Heather Eliassen, Susan E. Hankinson, Fred K. Tabung, Rulla M. Tamimi, Daniel G. Stover
Androgen receptor function and targeted therapeutics across breast cancer subtypes
Emily A. Kolyvas, Carlos Caldas, Kathleen Kelly, Saif S. Ahmad
Molecular intrinsic subtypes, genomic, and immune landscapes of BRCA-proficient but HRD-high ER-positive/HER2-negative early breast cancers
Elise Ballot, Loïck Galland, Hugo Mananet, Romain Boidot, Laurent Arnould, Isabelle Desmoulins, Didier Mayeur, Courèche Kaderbhai, Silvia Ilie, Audrey Hennequin, Anthony Bergeron, Valentin Derangère, François Ghiringhelli, Caroline Truntzer, Sylvain Ladoire
An integrated deep learning model for the prediction of pathological complete response to neoadjuvant chemotherapy with serial ultrasonography in breast cancer patients: a multicentre, retrospective study
Lei Wu, Weitao Ye, Yu Liu, Dong Chen, Yuxiang Wang, Yanfen Cui, Zhenhui Li, Pinxiong Li, Zhen Li, Zaiyi Liu, Min Liu, Changhong Liang, Xiaotang Yang, Yu Xie, Ying Wang
Correction: PredictCBC-2.0: a contralateral breast cancer risk prediction model developed and validated in ~ 200,000 patients
Daniele Giardiello, Maartje J. Hooning, Michael Hauptmann, Renske Keeman, B. A. M. Heemskerk-Gerritsen, Heiko Becher, Carl Blomqvist, Stig E. Bojesen, Manjeet K. Bolla, Nicola J. Camp, Kamila Czene, Peter Devilee, Diana M. Eccles, Peter A. Fasching, Jonine D. Figueroa, Henrik Flyger, Montserrat García-Closas, Christopher A. Haiman, Ute Hamann, John L. Hopper, Anna Jakubowska, Floor E. Leeuwen, Annika Lindblom, Jan Lubiński, Sara Margolin, Maria Elena Martinez, Heli Nevanlinna, Ines Nevelsteen, Saskia Pelders, Paul D. P. Pharoah, Sabine Siesling, Melissa C. Southey, Annemieke H. van der Hout, Liselotte P. van Hest, Jenny Chang-Claude, Per Hall, Douglas F. Easton, Ewout W. Steyerberg, Marjanka K. Schmidt
Intraoperative electron radiotherapy in early invasive ductal breast cancer: 6-year median follow-up results of a prospective monocentric registry
Catherine Philippson, Samuel Larsen, Stéphane Simon, Christophe Vandekerkhove, Alex De Caluwe, Dirk Van Gestel, Marie Chintinne, Isabelle Veys, Filip De Neubourg, Danièle Noterman, Mirela Roman, Jean-Marie Nogaret, Antoine Desmet
The bone–muscle connection in breast cancer: implications and therapeutic strategies to preserve musculoskeletal health
Tarah J. Ballinger, William R. Thompson, Theresa A. Guise
Volumetric imaging and morphometric analysis of breast tumor angiogenesis using a new contrast-free ultrasound technique: a feasibility study
Juanjuan Gu, Redouane Ternifi, Soroosh Sabeti, Nicholas B. Larson, Jodi M. Carter, Robert T. Fazzio, Mostafa Fatemi, Azra Alizad
Associations between quantitative measures of TDLU involution and breast tumor molecular subtypes among breast cancer cases in the Black Women’s Health Study: a case–case analysis
Brittny C. Davis Lynn, Brittany D. Lord, Renata Cora, Ruth M. Pfeiffer, Scott Lawrence, Gary Zirpoli, Traci N. Bethea, Julie R. Palmer, Gretchen L. Gierach
Evolution of breast cancer incidence in young women in a French registry from 1990 to 2018: Towards a change in screening strategy?
Yanis Hassaine, Emmanuelle Jacquet, Arnaud Seigneurin, Patricia Delafosse
Identification of a novel ER-NFĸB-driven stem-like cell population associated with relapse of ER+ breast tumors
Svetlana E. Semina, Luis H. Alejo, Shivani Chopra, Nidhi S. Kansara, Irida Kastrati, Carol A. Sartorius, Jonna Frasor
Associations of aspirin and other anti-inflammatory medications with breast cancer risk by the status of COX-2 expression
Lusine Yaghjyan, A. Heather Eliassen, Graham Colditz, Bernard Rosner, Pepper Schedin, Akemi Wijayabahu, Rulla M. Tamimi
Correlative studies of the Breast Cancer Index (HOXB13/IL17BR) and ER, PR, AR, AR/ER ratio and Ki67 for prediction of extended endocrine therapy benefit: a Trans-aTTom study
Dennis C. Sgroi, Kai Treuner, Yi Zhang, Tammy Piper, Ranelle Salunga, Ikhlaaq Ahmed, Lucy Doos, Sarah Thornber, Karen J. Taylor, Elena Brachtel, Sarah Pirrie, Catherine A. Schnabel, Daniel Rea, John M. S. Bartlett
Childhood adiposity, serum metabolites and breast density in young women
Joanne F. Dorgan, Heather J. Baer, Kimberly A. Bertrand, Erin S. LeBlanc, Seungyoun Jung, Laurence S. Magder, Linda G. Snetselaar, Victor J. Stevens, Yuji Zhang, Linda Van Horn
Ring finger protein 126 promotes breast cancer metastasis and serves as a potential target to improve the therapeutic sensitivity of ATR inhibitors
You Pan, Yuchao Yang, Rong Huang, Huawei Yang, Qinghua Huang, Yinan Ji, Jingxing Dai, Kun Qiao, Wei Tang, Longgui Xie, Ming Yin, Jun Ouyang, Shipeng Ning, Danke Su
Development and validation of an AI-enabled digital breast cancer assay to predict early-stage breast cancer recurrence within 6 years
Gerardo Fernandez, Marcel Prastawa, Abishek Sainath Madduri, Richard Scott, Bahram Marami, Nina Shpalensky, Krystal Cascetta, Mary Sawyer, Monica Chan, Giovanni Koll, Alexander Shtabsky, Aaron Feliz, Thomas Hansen, Brandon Veremis, Carlos Cordon-Cardo, Jack Zeineh, Michael J. Donovan
Definition of a novel breast tumor-specific classifier based on secretome analysis
Philémon Sirven, Lilith Faucheux, Maximilien Grandclaudon, Paula Michea, Anne Vincent-Salomon, Fatima Mechta-Grigoriou, Alix Scholer-Dahirel, Maude Guillot-Delost, Vassili Soumelis
Breast cancer worry, uncertainty, and perceived risk following breast density notification in a longitudinal mammography screening cohort
Erica J. Lee Argov, Carmen B. Rodriguez, Mariangela Agovino, Ying Wei, Rachel C. Shelton, Rita Kukafka, Karen M. Schmitt, Elise Desperito, Mary Beth Terry, Parisa Tehranifar
Microcalcifications, mammographic breast density, and risk of breast cancer: a cohort study
Soyeoun Kim, Thi Xuan Mai Tran, Huiyeon Song, Boyoung Park
Progesterone modulates the DSCAM-AS1/miR-130a/ESR1 axis to suppress cell invasion and migration in breast cancer
Neelima Yadav, Roma Sunder, Sanket Desai, Bhasker Dharavath, Pratik Chandrani, Mukul Godbole, Amit Dutt
Mebendazole prevents distant organ metastases in part by decreasing ITGβ4 expression and cancer stemness
Natalie S. Joe, Inês Godet, Nubaira Milki, Noor U. I. Ain, Harsh H. Oza, Gregory J. Riggins, Daniele M. Gilkes
SRC kinase-mediated signaling pathways and targeted therapies in breast cancer
Juan Luo, Hailin Zou, Yibo Guo, Tongyu Tong, Liping Ye, Chengming Zhu, Liang Deng, Bo Wang, Yihang Pan, Peng Li
Towards resolution of the intron retention paradox in breast cancer
Jaynish S. Shah, Michael J. G. Milevskiy, Veronika Petrova, Amy Y. M. Au, Justin J. L. Wong, Jane E. Visvader, Ulf Schmitz, John E. J. Rasko
Studies of parenchymal texture added to mammographic breast density and risk of breast cancer: a systematic review of the methods used in the literature
Akila Anandarajah, Yongzhen Chen, Graham A. Colditz, Angela Hardi, Carolyn Stoll, Shu Jiang