Ausgabe 6/2005
Inhalt (45 Artikel)
The estrogen receptor-α A908G (K303R) mutation occurs at a low frequency in invasive breast tumors: results from a population-based study
Kathleen Conway, Eloise Parrish, Sharon N Edmiston, Dawn Tolbert, Chiu-Kit Tse, Joseph Geradts, Chad A Livasy, Harsharan Singh, Beth Newman, Robert C Millikan
Cortactin overexpression results in sustained epidermal growth factor receptor signaling by preventing ligand-induced receptor degradation in human carcinoma cells
Agnes GSH van Rossum, Johan Gibcus, Jacqueline van der Wal, Ed Schuuring
Selective estrogen receptor modulators inhibit growth and progression of premalignant lesions in a mouse model of ductal carcinoma in situ
Ruria Namba, Lawrence JT Young, Jeannie E Maglione, Erik T McGoldrick, Stephenie Liu, Gregory T Wurz, Michael W DeGregorio, Alexander D Borowsky, Carol L MacLeod, Robert D Cardiff, Jeffrey P Gregg
Genetic polymorphisms in human SULT1A1 and UGT1A1 genes associate with breast tumor characteristics: a case-series study
Ekaterina G Shatalova, Susan E Walther, Olga O Favorova, Timothy R Rebbeck, Rebecca L Blanchard
CYP17 gene polymorphism in relation to breast cancer risk: a case-control study
Kristjana Einarsdóttir, Tove Rylander-Rudqvist, Keith Humphreys, Susanne Ahlberg, Gudrun Jonasdottir, Elisabete Weiderpass, Kee Seng Chia, Magnus Ingelman-Sundberg, Ingemar Persson, Jianjun Liu, Per Hall, Sara Wedrén
CYP17 and breast cancer: no overall effect, but what about interactions?
Julian Little, Jacques Simard
Clioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells
Kenyon G Daniel, Di Chen, Shirley Orlu, Qiuzhi Cindy Cui, Fred R Miller, Q Ping Dou
Targeted therapy against Bcl-2-related proteins in breast cancer cells
Manabu Emi, Ryungsa Kim, Kazuaki Tanabe, Yoko Uchida, Tetsuya Toge
Evolutionary conservation analysis increases the colocalization of predicted exonic splicing enhancers in the BRCA1gene with missense sequence changes and in-frame deletions, but not polymorphisms
Christopher Pettigrew, Nicola Wayte, Paul K Lovelock, Sean V Tavtigian, Georgia Chenevix-Trench, Amanda B Spurdle, Melissa A Brown
Gene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two population-based cohorts
Yudi Pawitan, Judith Bjöhle, Lukas Amler, Anna-Lena Borg, Suzanne Egyhazi, Per Hall, Xia Han, Lars Holmberg, Fei Huang, Sigrid Klaar, Edison T Liu, Lance Miller, Hans Nordgren, Alexander Ploner, Kerstin Sandelin, Peter M Shaw, Johanna Smeds, Lambert Skoog, Sara Wedrén, Jonas Bergh
CYP2D6 variants and the prediction of tamoxifen response in randomized patients: author response
Pia P Wegman, Sten Wingren
Positive association between mammographic breast density and bone mineral density in the Postmenopausal Estrogen/Progestin Interventions Study
Carolyn Crandall, Shana Palla, Beth A Reboussin, Giske Ursin, Gail A Greendale
Quantification of the response of circulating epithelial cells to neodadjuvant treatment for breast cancer: a new tool for therapy monitoring
Katharina Pachmann, Oumar Camara, Andreas Kavallaris, Uwe Schneider, Stefanie Schünemann, Klaus Höffken
Rac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cells
Paige J Baugher, Lakshmi Krishnamoorthy, Janet E Price, Surangani F Dharmawardhane
What does an orphan G-protein-coupled receptor have to do with estrogen?
James M Rae, Michael D Johnson
Key stages in mammary gland development: The mammary end bud as a motile organ
Lindsay Hinck, Gary B Silberstein
25-Hydroxyvitamin D31α-hydroxylase expression in breast cancer and use of non-1α-hydroxylated vitamin D analogue
Ulrika Segersten, Pernille Kaae Holm, Peyman Björklund, Ola Hessman, Hans Nordgren, Lise Binderup, Göran Åkerström, Per Hellman, Gunnar Westin
XRCC1 and XPDgenetic polymorphisms, smoking and breast cancer risk in a Finnish case-control study
Katja Metsola, Vesa Kataja, Pia Sillanpää, Päivi Siivola, Liisa Heikinheimo, Matti Eskelinen, Veli-Matti Kosma, Matti Uusitupa, Ari Hirvonen
Clinical trial update: International Breast Cancer Study Group
Karen N Price, Aron Goldhirsch
Patterns of reduced nipple aspirate fluid production and ductal lavage cellularity in women at high risk for breast cancer
Susan A Higgins, Ellen T Matloff, David L Rimm, James Dziura, Bruce G Haffty, Bonnie L King
Mutation analysis of FANCD2, BRIP1/BACH1, LMO4 and SFN in familial breast cancer
Aaron G Lewis, James Flanagan, Anna Marsh, Gulietta M Pupo, Graham Mann, Amanda B Spurdle, Geoffrey J Lindeman, Jane E Visvader, Melissa A Brown, Georgia Chenevix-Trench
Expression analysis of candidate breast tumour suppressor genes on chromosome 16q
Tom van Wezel, Marcel Lombaerts, Eddy H van Roon, Katja Philippo, Hans J Baelde, Karoly Szuhai, Cees J Cornelisse, Anne-Marie Cleton-Jansen
A common missense variant in BRCA2 predisposes to early onset breast cancer
Bohdan Górski, Steven A Narod, Jan Lubiński
Overdiagnosis and overtreatment of breast cancer: Overdiagnosis and overtreatment in service screening
Eugenio Paci, Stephen Duffy
The progestational and androgenic properties of medroxyprogesterone acetate: gene regulatory overlap with dihydrotestosterone in breast cancer cells
Radhika P Ghatge, Britta M Jacobsen, Stephanie A Schittone, Kathryn B Horwitz
Metaplastic breast carcinomas exhibit EGFR, but not HER2, gene amplification and overexpression: immunohistochemical and chromogenic in situ hybridization analysis
Jorge S Reis-Filho, Fernanda Milanezi, Silvia Carvalho, Pete T Simpson, Dawn Steele, Kay Savage, Maryou BK Lambros, Emilio M Pereira, Jahn M Nesland, Sunil R Lakhani, Fernando C Schmitt
Tamoxifen may prevent both ER+ and ER- breast cancers and select for ER- carcinogenesis: an alternative hypothesis
Laura J Esserman, Elissa M Ozanne, Mitch Dowsett, Joyce M Slingerland
HER-2 overexpression differentially alters transforming growth factor-β responses in luminal versus mesenchymal human breast cancer cells
Cindy A Wilson, Elaina E Cajulis, Jennifer L Green, Taylor M Olsen, Young Ah Chung, Michael A Damore, Judy Dering, Frank J Calzone, Dennis J Slamon
Effects of combined treatment with rapamycin and cotylenin A, a novel differentiation-inducing agent, on human breast carcinoma MCF-7 cells and xenografts
Takashi Kasukabe, Junko Okabe-Kado, Nobuo Kato, Takeshi Sassa, Yoshio Honma
Antisense oligonucleotides targeting the progesterone receptor inhibit hormone-independent breast cancer growth in mice
Caroline A Lamb, Luisa A Helguero, Sebastián Giulianelli, Rocío Soldati, Silvia I Vanzulli, Alfredo Molinolo, Claudia Lanari
Overdiagnosis and overtreatment of breast cancer: Rates of ductal carcinoma in situ: a US perspective
Anjali S Kumar, Vinona Bhatia, I Craig Henderson
Aromatase inhibitors as adjuvant therapy for postmenopausal women: a therapeutic advance but many unresolved questions
Jennifer A Ligibel, Eric P Winer
Nipple aspiration and ductal lavage in women with a germline BRCA1 or BRCA2 mutation
Gillian Mitchell, Yoland C Antill, William Murray, Judy Kirk, Elizabeth Salisbury, Geoffrey J Lindeman, Juliana Di Iulio, Alvin D Milner, Lisa Devereaux, Kelly-Anne Phillips
Allelic imbalances of chromosomes 8p and 18q and their roles in distant relapse of early stage, node-negative breast cancer
Aki Morikawa, Tanisha Y Williams, Luc Dirix, Cecile Colpaert, Michael Goodman, Robert H Lyles, Diansheng Zhong, Wei Zhou
Dehydroepiandrosterone inhibits the progression phase of mammary carcinogenesis by inducing cellular senescence via a p16-dependent but p53-independent mechanism
Anne Shilkaitis, Albert Green, Vasu Punj, Vernon Steele, Ronald Lubet, Konstantin Christov
Inhibition of CCN6 (WISP3) expression promotes neoplastic progression and enhances the effects of insulin-like growth factor-1 on breast epithelial cells
Yanhong Zhang, Quintin Pan, Hui Zhong, Sofia D Merajver, Celina G Kleer
Breast cancer histological classification: agreement between the Office for National Statistics and the National Health Service Breast Screening Programme
Toral Gathani, Diana Bull, Jane Green, Gillian Reeves, Valerie Beral
Preclinical evaluation of transcriptional targeting strategies for carcinoma of the breast in a tissue slice model system
Mariam A Stoff-Khalili, Alexander Stoff, Angel A Rivera, Nilam S Banerjee, Maaike Everts, Scott Young, Gene P Siegal, Dirk F Richter, Minghui Wang, Peter Dall, J Michael Mathis, Zeng B Zhu, David T Curiel
Overdiagnosis and overtreatment of breast cancer: Estimates of overdiagnosis from two trials of mammographic screening for breast cancer
Stephen W Duffy, Olorunsola Agbaje, Laszlo Tabar, Bedrich Vitak, Nils Bjurstam, Lena Björneld, Jonathan P Myles, Jane Warwick
A prospective study of XRCC1(X-ray cross-complementing group 1) polymorphisms and breast cancer risk
Alpa V Patel, Eugenia E Calle, Alexandre L Pavluck, Heather Spencer Feigelson, Michael J Thun, Carmen Rodriguez
High resolution genomic analysis of sporadic breast cancer using array-based comparative genomic hybridization
Tara L Naylor, Joel Greshock, Yan Wang, Theresa Colligon, QC Yu, Virginia Clemmer, Tal Z Zaks, Barbara L Weber
Farnesyl-transferase inhibitor R115,777 enhances tamoxifen inhibition of MCF-7 cell growth through estrogen receptor dependent and independent pathways
Florence Dalenc, Claire Giamarchi, Mélissa Petit, Marc Poirot, Gilles Favre, Jean-Charles Faye
Imaging in breast cancer: Diffuse optics in breast cancer: detecting tumors in pre-menopausal women and monitoring neoadjuvant chemotherapy
Bruce J Tromberg, Albert Cerussi, Natasha Shah, Montana Compton, Amanda Durkin, David Hsiang, John Butler, Rita Mehta
Prognostic relevance of disseminated tumor cells in the bone marrow and biological factors of 265 primary breast carcinomas
Christian Schindlbeck, Theresa Kampik, Wolfgang Janni, Brigitte Rack, Udo Jeschke, Stan Krajewski, Harald Sommer, Klaus Friese