Ausgabe 3/2013
Inhalt (30 Artikel)
Marqibo® (vincristine sulfate liposome injection) improves the pharmacokinetics and pharmacodynamics of vincristine
Jeffrey A. Silverman, Steven R. Deitcher
A randomized, double-blind, placebo-controlled study to evaluate the effect of repeated oral doses of pazopanib on cardiac conduction in patients with solid tumors
Elisabeth I. Heath, Jeffrey Infante, Lionel D. Lewis, Thehang Luu, Joe Stephenson, Antoinette R. Tan, Saifuddin Kasubhai, Patricia LoRusso, Bo Ma, A. Benjamin Suttle, Joseph F. Kleha, Howard A. Ball, Mohammed M. Dar
Characterization of the long-term pharmacokinetics of bevacizumab following last dose in patients with resected stage II and III carcinoma of the colon
Jing Li, Manish Gupta, Denise Jin, Yan Xin, Jennifer Visich, David E. Allison
Acadesine for patients with relapsed/refractory chronic lymphocytic leukemia (CLL): a multicenter phase I/II study
Eric Van Den Neste, Bruno Cazin, Ann Janssens, Eva González-Barca, María José Terol, Vincent Levy, Jaime Pérez de Oteyza, Pierre Zachee, Andrew Saunders, Mercè de Frias, Clara Campàs
The use of the 13C-dextromethorphan breath test for phenotyping CYP2D6 in breast cancer patients using tamoxifen: association with CYP2D6 genotype and serum endoxifen levels
F. L. Opdam, V. O. Dezentje, J. den Hartigh, A. S. Modak, R. Vree, E. Batman, C. H. Smorenburg, J. W. R. Nortier, H. Gelderblom, H.-J. Guchelaar
Erratum to: The use of the 13C-dextromethorphan breath test for phenotyping CYP2D6 in breast cancer patients using tamoxifen: association with CYP2D6 genotype and serum endoxifen levels
F. L. Opdam, V. O. Dezentje, J. den Hartigh, A. S. Modak, R. Vree, E. Batman, C. H. Smorenburg, J. W. R. Nortier, H. Gelderblom, H.-J. Guchelaar
Docetaxel plus cisplatin and bevacizumab for untreated patients with advanced/metastatic non-squamous non-small-cell lung cancer: a multicenter phase II study of the Hellenic Oncology Research Group
N. Kentepozidis, A. Kotsakis, A. Soultati, S. Agelaki, Ch. Christophylakis, M. Agelidou, L. Chelis, P. Papakotoulas, L. Vamvakas, Z. Zafiriou, G. Samonis, V. Georgoulias
Capecitabine and oxaliplatin in combination as first- or second-line therapy for metastatic breast cancer: a Wisconsin Oncology Network trial
U. O. Njiaju, A. J. Tevaarwerk, K. Kim, J. E. Chang, R. M. Hansen, T. L. Champeny, A. M. Traynor, S. Meadows, L. Van Ummersen, K. Powers, J. A. Stewart
Persistent chemoneuropathy in patients receiving the plant alkaloids paclitaxel and vincristine
Jessica A. Boyette-Davis, Juan P. Cata, Larry C. Driver, Diane M. Novy, Brian M. Bruel, Deidre L. Mooring, Gwen Wendelschafer-Crabb, William R. Kennedy, Patrick M. Dougherty
A phase I study of liposomal-encapsulated docetaxel (LE-DT) in patients with advanced solid tumor malignancies
John F. Deeken, Rebecca Slack, Glen J. Weiss, Ramesh K. Ramanathan, Michael J. Pishvaian, Jimmy Hwang, Karen Lewandowski, Deepa Subramaniam, Aiwu Ruth He, Ion Cotarla, Aquilur Rahman, John L. Marshall
Potential role of acid ceramidase in conversion of cytostatic to cytotoxic end-point in pancreatic cancer cells
Samy A. F. Morad, Maria C. Messner, Jonathan C. Levin, Noha Abdelmageed, Hyejung Park, Alfred H. Merrill Jr., Myles C. Cabot
Phase I dose-escalation study of oral vinflunine administered once daily for 6 weeks every 8 weeks in patients with advanced/metastatic solid tumours
J. P. Delord, J. M. Tourani, F. Lefresne, A. Pétain, J.-C. Pouget, A. Ravaud
Neoadjuvant chemotherapy using platinum- and taxane-based regimens for bulky stage Ib2 to IIb non-squamous cell carcinoma of the uterine cervix
Tadahiro Shoji, Eriko Takatori, Tatsunori Saito, Hideo Omi, Masahiro Kagabu, Fumiharu Miura, Satoshi Takeuchi, Toru Sugiyama
Capecitabine and temozolomide (CAPTEM) for metastatic, well-differentiated neuroendocrine cancers: The Pancreas Center at Columbia University experience
Robert L. Fine, Anthony P. Gulati, Benjamin A. Krantz, Rebecca A. Moss, Stephen Schreibman, Dawn A. Tsushima, Kelley B. Mowatt, Richard D. Dinnen, Yuehua Mao, Peter D. Stevens, Beth Schrope, John Allendorf, James A. Lee, William H. Sherman, John A. Chabot
Concomitant high gene copy number and protein overexpression of IGF1R and EGFR negatively affect disease-free survival of surgically resected non-small-cell-lung cancer patients
V. Ludovini, A. Flacco, F. Bianconi, M. Ragusa, J. Vannucci, G. Bellezza, R. Chiari, V. Minotti, L. Pistola, F. R. Tofanetti, A. Siggillino, E. Baldelli, A. Sidoni, N. Daddi, F. Puma, M. Varella-Garcia, L. Crinò
Population pharmacokinetics of cabazitaxel in patients with advanced solid tumors
Géraldine M. Ferron, Yang Dai, Dorothée Semiond
Population pharmacokinetics of hyperthermic intraperitoneal oxaliplatin in patients with peritoneal carcinomatosis after cytoreductive surgery
Carlos Pérez-Ruixo, Belén Valenzuela, José Esteban Peris, Pedro Bretcha-Boix, Vanesa Escudero-Ortiz, José Farré-Alegre, Juan José Pérez-Ruixo
Phase I/II study of amrubicin in combination with S-1 as second-line chemotherapy for non-small-cell lung cancer without EGFR mutation
Shuji Murakami, Fumihiro Oshita, Makiko Sugiura, Tetsuro Kondo, Haruhiro Saito, Kouzo Yamada
(−)-Epigallocatechin-3-gallate inhibits human papillomavirus (HPV)-16 oncoprotein-induced angiogenesis in non-small cell lung cancer cells by targeting HIF-1α
Li He, Erying Zhang, Jingli Shi, Xiangyong Li, Keyuan Zhou, Qunzhou Zhang, Anh D. Le, Xudong Tang
Pharmacokinetics of docetaxel in gastric cancer patients with malignant ascites
Hidenori Tamegai, Teruo Kaiga, Mitsugu Kochi, Masashi Fujii, Noriaki Kanamori, Yoshiaki Mihara, Tomoya Funada, Hiroko Shimizu, Daijo Jinno, Tadatoshi Takayama
XRCC1 and GSTP1 polymorphisms and prognosis of oxaliplatin-based chemotherapy in colorectal cancer: a meta-analysis
Fanghui Ye, Zhenfang Liu, Aihua Tan, Ming Liao, Zengnan Mo, Xiaobo Yang
Low dose capecitabine plus weekly paclitaxel in patients with metastatic breast cancer: a multicenter phase II study KBCSG-0609
Tetsuya Taguchi, Daigo Yamamoto, Norikazu Masuda, Koji Oba, Takahiro Nakayama, Takuya Nagata, Masaya Nomura, Katsuhide Yoshidome, Hiroshi Yoshino, Nobuki Matsunami, Masaru Miyashita, Yoshihiko Furuya, Takanori Ishida, Kazuyuki Wakita, Junichi Sakamoto, Shinzaburo Noguchi
Population pharmacokinetics of doxorubicin: establishment of a NONMEM model for adults and children older than 3 years
Nina E. Kontny, Gudrun Würthwein, Boos Joachim, Alan V. Boddy, Miriam Krischke, Uwe Fuhr, Patrick A. Thompson, Markus Jörger, Jan H. M. Schellens, Georg Hempel
Pharmacological ascorbate with gemcitabine for the control of metastatic and node-positive pancreatic cancer (PACMAN): results from a phase I clinical trial
J. L. Welsh, B. A. Wagner, T. J. van’t Erve, P. S. Zehr, D. J. Berg, T. R. Halfdanarson, N. S. Yee, K. L. Bodeker, J. Du, L. J. Roberts II, J. Drisko, M. Levine, G. R. Buettner, J. J. Cullen
p75NTR: an enhancer of fenretinide toxicity in neuroblastoma
Veena Ganeshan, John Ashton, Nina F. Schor
A phase II study of neoadjuvant combination chemotherapy with docetaxel, cisplatin, and S-1 for locally advanced resectable gastric cancer: nucleotide excision repair (NER) as potential chemoresistance marker
Masahiro Hirakawa, Yasushi Sato, Hiroyuki Ohnuma, Tetsuji Takayama, Tamotsu Sagawa, Takayuki Nobuoka, Keisuke Harada, Hiroshi Miyamoto, Yasuhiro Sato, Yasuo Takahashi, Shinich Katsuki, Michiaki Hirayama, Minoru Takahashi, Michihiro Ono, Masahiro Maeda, Kohichi Takada, Tsuyoshi Hayashi, Tsutomu Sato, Koji Miyanishi, Rishu Takimoto, Masayoshi Kobune, Koichi Hirata, Junji Kato
Immunogenicity and toxicity of transferrin receptor-targeted hybrid peptide as a potent anticancer agent
Megumi Kawamoto, Masayuki Kohno, Tomohisa Horibe, Koji Kawakami
The hydroxyl epimer of doxorubicin controls the rate of formation of cytotoxic anthracycline-DNA adducts
Robert A. Forrest, Lonnie P. Swift, Benny J. Evison, Ada Rephaeli, Abraham Nudelman, Don R. Phillips, Suzanne M. Cutts
Investigating the role of nucleoside transporters in the resistance of colorectal cancer to 5-fluorouracil therapy
Lee Cheng Phua, Mainak Mal, Poh Koon Koh, Peh Yean Cheah, Eric Chun Yong Chan, Han Kiat Ho
Immunohistochemical study of MRP5 expression in meningiomas
George A. Alexiou, Ann Goussia, Antigoni Ntoulia, Panagiota Zagorianakou, Vasiliki Malamou-Mitsi, Spyridon Voulgaris, Athanasios P. Kyritsis