Ausgabe 6/2015
Inhalt (24 Artikel)
Expert consensus for the management of advanced or metastatic pancreatic neuroendocrine and carcinoid tumors
Daniel Castellano, Enrique Grande, Juan Valle, Jaume Capdevila, Diane Reidy-Lagunes, Juan Manuel O’Connor, Eric Raymond
Safety and feasibility of S-1 adjuvant chemotherapy for pancreatic cancer in elderly patients
Toru Aoyama, Yusuke Katayama, Masaaki Murakawa, Yosuke Atsumi, Koichiro Yamaoku, Amane Kanazawa, Akio Higuchi, Manabu Shiozawa, Satoshi Kobayashi, Makoto Ueno, Manabu Morimoto, Naoto Yamamoto, Takashi Oshima, Takaki Yoshikawa, Yasushi Rino, Munetaka Masuda, Soichiro Morinaga
DNA intercalative 4-butylaminopyrimido[4′,5′:4,5]thieno(2,3-b)quinoline induces cell cycle arrest and apoptosis in leukemia cells
Heggodu G. RohitKumar, Kittur R. Asha, Sathees C. Raghavan, Gopal M. Advi Rao
Phase II study of capecitabine and the oral mTOR inhibitor everolimus in patients with advanced pancreatic cancer
S. Kordes, H. J. Klümpen, M. J. Weterman, J. H. M. Schellens, D. J. Richel, J. W. Wilmink
Pharmacokinetic and pharmacodynamic profile of bendamustine and its metabolites
Mona Darwish, Mary Bond, Edward Hellriegel, Philmore Robertson Jr., James P. Chovan
A phase I study of resminostat in Japanese patients with advanced solid tumors
Satoru Kitazono, Yutaka Fujiwara, Shinji Nakamichi, Hidenori Mizugaki, Hiroshi Nokihara, Noboru Yamamoto, Yasuhide Yamada, Eri Inukai, Osamu Nakamura, Tomohide Tamura
Determinants of the activities of antifolates delivered into cells by folate-receptor-mediated endocytosis
Rongbao Zhao, Michele Visentin, I. David Goldman
A phase I/II trial of second-line chemotherapy with paclitaxel and irinotecan in fluoropyrimidine- and platinum-pretreated patients with advanced gastric cancer
Jin Won Kim, In Sil Choi, Yu Jung Kim, Kyung-Hun Lee, Keun-Wook Lee, Tae-Yong Kim, Sae-Won Han, Jee Hyun Kim, Tae-You Kim, Jong Seok Lee, Yung-Jue Bang, Seock-Ah Im, Do-Youn Oh
Randomized study of orally administered fluorinated pyrimidines (capecitabine versus S-1) in women with metastatic or recurrent breast cancer: Japan Breast Cancer Research Network 05 Trial
D. Yamamoto, S. Iwase, Y. Tsubota, K. Ariyoshi, T. Kawaguchi, T. Miyaji, N. Sueoka, C. Yamamoto, S. Teramoto, H. Odagiri, K. Kitamura, Y. Nagumo, T. Yamaguchi
Association of decreased mRNA expression of multidrug and toxin extrusion protein 1 in peripheral blood cells with the development of flutamide-induced liver injury
Kazuhiko Nakano, Hitoshi Ando, Shinsuke Kurokawa, Keiko Hosohata, Kentarou Ushijima, Makoto Takada, Masato Tateishi, Atsushi Yonezawa, Satohiro Masuda, Kazuo Matsubara, Ken-ichi Inui, Tatsuo Morita, Akio Fujimura
Comparison of pharmacokinetics and safety of pegfilgrastim administered by two delivery methods: on-body injector and manual injection with a prefilled syringe
Bing-Bing Yang, Phuong Khanh Morrow, Xikun Wu, Michael Moxness, Desmond Padhi
Functional polymorphisms of ITGB1 are associated with clinical outcome of Chinese patients with resected colorectal cancer
Feng Zhou, Xiaojun Huang, Zhaohui Zhang, Yibing Chen, Xiaonan Liu, Jinliang Xing, Xianli He
Cisplatin resistance in human cervical, ovarian and lung cancer cells
Jianli Chen, Charalambos Solomides, Hemant Parekh, Fiona Simpkins, Henry Simpkins
A phase II trial of gefitinib monotherapy in pretreated patients with advanced non-small cell lung cancer not harboring activating EGFR mutations: implications of sensitive EGFR mutation test
Moon Ki Choi, Jung Yong Hong, Won Jin Chang, Moon Jin Kim, Sung Min Kim, Hyun Ae Jung, In-Gu Do, Yoon-la Choi, Jong-Mu Sun, Jin Seok Ahn, Keunchil Park, Myung-Ju Ahn
Modulation of Regorafenib effects on HCC cell lines by epidermal growth factor
Rosalba D’Alessandro, Maria Grazia Refolo, Catia Lippolis, Nicola Carella, Caterina Messa, Aldo Cavallini, Brian Irving Carr
Methylthioadenosine phosphorylase (MTAP)-deficient T-cell ALL xenografts are sensitive to pralatrexate and 6-thioguanine alone and in combination
Philip M. Tedeschi, Yamini K. Kathari, Nadine Johnson-Farley, Joseph R. Bertino
Inhibition of SN-38 glucuronidation by gefitinib and its metabolite
Wei Li, Yafei Xing, Yong Liu
High-dose erlotinib for refractory leptomeningeal metastases after failure of standard-dose EGFR-TKIs
Takahisa Kawamura, Akito Hata, Jumpei Takeshita, Shiro Fujita, Michio Hayashi, Keisuke Tomii, Nobuyuki Katakami
A phase II study of pemetrexed monotherapy in chemo-naïve Eastern Cooperative Oncology Group performance status 2 patients with EGFR wild-type or unknown advanced non-squamous non-small cell lung cancer (HANSHIN Oncology Group 002)
Akito Hata, Nobuyuki Katakami, Shiro Fujita, Shigeki Nanjo, Jumpei Takeshita, Kosuke Tanaka, Toshihiko Kaneda, Akihiro Nishiyama, Takashi Nishimura, Atsushi Nakagawa, Kojiro Otsuka, Satoshi Morita, Yoshiko Urata, Shunichi Negoro
Docetaxel in combination with octreotide shows synergistic apoptotic effect by increasing SSTR2 and SSTR5 expression levels in prostate and breast cancer cell lines
Burcak Karaca, Mustafa Degirmenci, Ahmet Ozveren, Harika Atmaca, Emir Bozkurt, Bulent Karabulut, Ulus Ali Sanli, Ruchan Uslu
Phase II multicenter study of adjuvant S-1 for colorectal liver metastasis: survival analysis of N-SOG 01 trial
Takehiro Kato, Keisuke Uehara, Atsuyuki Maeda, Eiji Sakamoto, Kazuhiro Hiramatsu, Eiji Takeuchi, Hidenari Goto, Yuichiro Tojima, Hiroshi Yatsuya, Masato Nagino
PAI-1 and HER2 interaction in advanced breast cancer disease: evidence for added benefit from trastuzumab in HER2-negative patients
Anna Koumarianou, Georgia Karayannopoulou, Georgia Gourgioti, Anna Batistatou, Mattheos Bobos, Ioannis Efstratiou, Dimosthenis Miliaras, Eleni Galani, George Pentheroudakis, Dimitrios Pectasides, Gerasimos Aravantinos, Dimitrios Bafaloukos, Pavlos Papakostas, Evangelia Razis, Haralabos P. Kalofonos, Kalliopi Petraki, Maria Sotiropoulou, Konstantine T. Kalogeras, George Fountzilas
The newly synthesized 2-arylnaphthyridin-4-one, CSC-3436, induces apoptosis of non-small cell lung cancer cells by inhibiting tubulin dynamics and activating CDK1
Ling-Chu Chang, Yung-Luen Yu, Chin-Yu Liu, Yung-Yi Cheng, Ruey-Hwang Chou, Min-Tsang Hsieh, Hui-Yi Lin, Hsin-Yi Hung, Li-Jiau Huang, Yang-Chang Wu, Sheng-Chu Kuo
Targeting the EWS–FLI1 transcription factor in Ewing sarcoma
R. Tancredi, A. Zambelli, G. A. DaPrada, V. Fregoni, L. Pavesi, A. Riccardi, S. Burdach, P. J. Grohar, M. D’Incalci