Skip to main content
Erschienen in: Current Treatment Options in Cardiovascular Medicine 5/2010

01.10.2010 | Arrhythmias

Cardiac Arrhythmias During Pregnancy

verfasst von: Thomas Adam Burkart, MD, Jamie Beth Conti, MD

Erschienen in: Current Treatment Options in Cardiovascular Medicine | Ausgabe 5/2010

Einloggen, um Zugang zu erhalten

Opinion statement

This article reviews the appropriate evaluation and management of cardiac arrhythmias in the pregnant patient. Any treatment strategy in this patient population has the inherent potential to adversely affect the health of the unborn child. As such, there is no room for empiric therapy in these patients. Adequate arrhythmia documentation is paramount, preferably by noninvasive means. The decision to treat should be based on symptom severity and the risk to both mother and fetus posed by potentially recurring arrhythmia episodes throughout the pregnancy. Minimal symptoms in the setting of a structurally normal heart call for a conservative approach. Less is better. If pharmacologic therapy is justified, drugs with historically demonstrated safety profiles in pregnancy should be tried first. The safety profiles of virtually all drugs used to treat cardiac arrhythmias during human pregnancy are based solely on an accumulation of past clinical experience. Newer antiarrhythmics therefore carry a largely unknown risk. Most inherent rhythm disorders manifest long before a woman reaches childbearing age. Women with previously diagnosed arrhythmias frequently experience a recurrence or worsening of their arrhythmia during the pregnancy. Counseling of these individuals and perhaps preemptive treatment by means such as arrhythmia ablation prior to a planned pregnancy would seem optimal.
Literatur
1.•
Zurück zum Zitat Li JM, Nguyen C, Joglar JA, et al.: Frequency and outcome of arrhythmias complicating admission during pregnancy: experience from a high-volume and ethnically diverse obstetric service. Clin Cardiol 2008, 31:538–541.CrossRefPubMed Li JM, Nguyen C, Joglar JA, et al.: Frequency and outcome of arrhythmias complicating admission during pregnancy: experience from a high-volume and ethnically diverse obstetric service. Clin Cardiol 2008, 31:538–541.CrossRefPubMed
2.
Zurück zum Zitat Tawam M, Levine J, Mendelson M, et al.: Effect of pregnancy on paroxysmal supraventricular tachycardia. Am J Cardiol 1993, 72:838.CrossRefPubMed Tawam M, Levine J, Mendelson M, et al.: Effect of pregnancy on paroxysmal supraventricular tachycardia. Am J Cardiol 1993, 72:838.CrossRefPubMed
3.
Zurück zum Zitat Silversides CK, Harris L, Haberer K, et al.: Recurrence rates of arrhythmias during pregnancy in women with previous tachyarrhythmia and impact on fetal and neonatal outcomes. Am J Cardiol 2006, 97:1206–1212.CrossRefPubMed Silversides CK, Harris L, Haberer K, et al.: Recurrence rates of arrhythmias during pregnancy in women with previous tachyarrhythmia and impact on fetal and neonatal outcomes. Am J Cardiol 2006, 97:1206–1212.CrossRefPubMed
4.
Zurück zum Zitat Lee SH, Chen SA, Wu TJ, et al.: Effects of pregnancy on first onset and symptoms of paroxysmal supraventricular tachycardia. Am J Cardiol 1995, 76:675.CrossRefPubMed Lee SH, Chen SA, Wu TJ, et al.: Effects of pregnancy on first onset and symptoms of paroxysmal supraventricular tachycardia. Am J Cardiol 1995, 76:675.CrossRefPubMed
5.
Zurück zum Zitat Dean M, Stock B, Patterson RJ, et al.: Serum protein binding of drugs during and after pregnancy in humans. Clin Pharmacol Ther 1980, 28:253.CrossRefPubMed Dean M, Stock B, Patterson RJ, et al.: Serum protein binding of drugs during and after pregnancy in humans. Clin Pharmacol Ther 1980, 28:253.CrossRefPubMed
6.
Zurück zum Zitat Mitani GM, Steinberg I, Lien EJ, et al.: The pharmacokinetics of antiarrhythmic agents in pregnancy and lactation. Clin Pharmacokinet 1987, 12:253.CrossRefPubMed Mitani GM, Steinberg I, Lien EJ, et al.: The pharmacokinetics of antiarrhythmic agents in pregnancy and lactation. Clin Pharmacokinet 1987, 12:253.CrossRefPubMed
7.
Zurück zum Zitat Herngren L, Ehrnebo M, Boreus LO: Drug binding to plasma proteins during human pregnancy and in the perinatal period. Studies on cloxacillin and alprenolol. Dev Pharmacol Ther 1983, 6:110.PubMed Herngren L, Ehrnebo M, Boreus LO: Drug binding to plasma proteins during human pregnancy and in the perinatal period. Studies on cloxacillin and alprenolol. Dev Pharmacol Ther 1983, 6:110.PubMed
8.
Zurück zum Zitat Miller RW: Intrauterine radiation exposures and mental retardation. Health Phys 1988, 55:295.CrossRefPubMed Miller RW: Intrauterine radiation exposures and mental retardation. Health Phys 1988, 55:295.CrossRefPubMed
9.
Zurück zum Zitat Doll R, Wakeford R: Risk of childhood cancer from fetal irradiation. Br J Radiol 1997, 70:130.PubMed Doll R, Wakeford R: Risk of childhood cancer from fetal irradiation. Br J Radiol 1997, 70:130.PubMed
10.
Zurück zum Zitat Brent RL: The effect of embryonic and fetal exposure to x-ray, microwaves, and ultrasound: counseling the pregnant and nonpregnant patient about these risks. Semin Oncol 1989, 16:347.PubMed Brent RL: The effect of embryonic and fetal exposure to x-ray, microwaves, and ultrasound: counseling the pregnant and nonpregnant patient about these risks. Semin Oncol 1989, 16:347.PubMed
11.
Zurück zum Zitat Dominguez A, Iturralde P, Hermosillo AG, et al.: Successful radiofrequency ablation of an accessory pathway during pregnancy. Pacing Clin Electrophysiol 1999, 22:131.CrossRefPubMed Dominguez A, Iturralde P, Hermosillo AG, et al.: Successful radiofrequency ablation of an accessory pathway during pregnancy. Pacing Clin Electrophysiol 1999, 22:131.CrossRefPubMed
12.
Zurück zum Zitat ACC/AHA/HRS 2008 Guidelines for device-based therapy of cardiac rhythm abnormalities. J Am Coll Cardiol 2008; 51(21):e1–e62. ACC/AHA/HRS 2008 Guidelines for device-based therapy of cardiac rhythm abnormalities. J Am Coll Cardiol 2008; 51(21):e1–e62.
13.
Zurück zum Zitat Kosinski D, Grubb BP: Vasodepressor syncope. Curr Treat Options Cardiovasc Med 2000, 2:309–315.CrossRefPubMed Kosinski D, Grubb BP: Vasodepressor syncope. Curr Treat Options Cardiovasc Med 2000, 2:309–315.CrossRefPubMed
14.
Zurück zum Zitat Anderson MH: Rhythm disorders. In Heart Disease in Pregnancy. By Oakley C. London: BMJ Publishing Group; 1997:248. Anderson MH: Rhythm disorders. In Heart Disease in Pregnancy. By Oakley C. London: BMJ Publishing Group; 1997:248.
15.
16.
Zurück zum Zitat Widerhorn J, Widerhorn AL, Rahimtoola SH, et al.: WPW syndrome during pregnancy: increased incidence of supraventricular arrhythmias. Am Heart J 1992, 123:796.CrossRefPubMed Widerhorn J, Widerhorn AL, Rahimtoola SH, et al.: WPW syndrome during pregnancy: increased incidence of supraventricular arrhythmias. Am Heart J 1992, 123:796.CrossRefPubMed
17.
Zurück zum Zitat Mason BA, Ricci-Goodman J, Koos BJ: Adenosine in the treatment of maternal paroxysmal supraventricular tachycardia. Obstet Gynecol 1992, 80:478.PubMed Mason BA, Ricci-Goodman J, Koos BJ: Adenosine in the treatment of maternal paroxysmal supraventricular tachycardia. Obstet Gynecol 1992, 80:478.PubMed
18.
Zurück zum Zitat DiMarco JP, Sellers TD, Lerman BB, et al.: Diagnostic and therapeutic use of adenosine in patients with supraventricular tachyarrhythmias. J Am Coll Cardiol 1985, 6:417.CrossRefPubMed DiMarco JP, Sellers TD, Lerman BB, et al.: Diagnostic and therapeutic use of adenosine in patients with supraventricular tachyarrhythmias. J Am Coll Cardiol 1985, 6:417.CrossRefPubMed
19.
Zurück zum Zitat Elkayam U, Goodwin M: Safety and efficacy of intravenous adenosine therapy for supraventricular tachycardia during pregnancy—results of a national survey. J Am Coll Cardiol 1994, 23(suppl A):91A. Elkayam U, Goodwin M: Safety and efficacy of intravenous adenosine therapy for supraventricular tachycardia during pregnancy—results of a national survey. J Am Coll Cardiol 1994, 23(suppl A):91A.
20.
Zurück zum Zitat Klein V, Repke JT: Supraventricular tachycardia in pregnancy: cardioversion with verapamil. Obstet Gynecol 1984, 63(Suppl 3):16S.PubMed Klein V, Repke JT: Supraventricular tachycardia in pregnancy: cardioversion with verapamil. Obstet Gynecol 1984, 63(Suppl 3):16S.PubMed
21.
Zurück zum Zitat Heaton FC, Vaughan R: Intrauterine supraventricular tachycardia: cardioversion with maternal digoxin. Obstet Gynecol 1982, 60:749.PubMed Heaton FC, Vaughan R: Intrauterine supraventricular tachycardia: cardioversion with maternal digoxin. Obstet Gynecol 1982, 60:749.PubMed
22.
Zurück zum Zitat El-Sayed YY, Holbrook Jr RH, Gibson R, et al.: Diltiazem for maintenance tocolysis of preterm labor: comparison to nifedipine in a randomized trial. J Matern Fetal Med 1998, 7:217.CrossRefPubMed El-Sayed YY, Holbrook Jr RH, Gibson R, et al.: Diltiazem for maintenance tocolysis of preterm labor: comparison to nifedipine in a randomized trial. J Matern Fetal Med 1998, 7:217.CrossRefPubMed
23.
Zurück zum Zitat ECC Committee, Subcommittees and Task Forces of the American Heart Association: 2005 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Part 7.3: management of symptomatic bradycardia and tachycardia. Circulation 2005, 112(suppl I):IV67–IV77. ECC Committee, Subcommittees and Task Forces of the American Heart Association: 2005 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Part 7.3: management of symptomatic bradycardia and tachycardia. Circulation 2005, 112(suppl I):IV67–IV77.
24.
Zurück zum Zitat Rotmensch HH, Elkayam U, Frishman W: Antiarrhythmic drug therapy during pregnancy. Ann Intern Med 1983, 98:487.PubMed Rotmensch HH, Elkayam U, Frishman W: Antiarrhythmic drug therapy during pregnancy. Ann Intern Med 1983, 98:487.PubMed
25.••
Zurück zum Zitat Qasqas SA, McPherson C, Frishman WH, Elkayam U: Cardiovascular pharmacotherapeutic considerations during pregnancy and lactation. Cardiol Rev 2004, 12:201–221.CrossRefPubMed Qasqas SA, McPherson C, Frishman WH, Elkayam U: Cardiovascular pharmacotherapeutic considerations during pregnancy and lactation. Cardiol Rev 2004, 12:201–221.CrossRefPubMed
26.
Zurück zum Zitat Hill LM, Malkasian Jr GD: The use of quinidine sulfate throughout pregnancy. Obstet Gynecol 1979, 54:366.PubMed Hill LM, Malkasian Jr GD: The use of quinidine sulfate throughout pregnancy. Obstet Gynecol 1979, 54:366.PubMed
27.
Zurück zum Zitat Dumesic DA, Silverman NH, Tobias S, et al.: Transplacental cardioversion of fetal supraventricular tachycardia with procainamide. N Engl J Med 1982, 307:1128.CrossRefPubMed Dumesic DA, Silverman NH, Tobias S, et al.: Transplacental cardioversion of fetal supraventricular tachycardia with procainamide. N Engl J Med 1982, 307:1128.CrossRefPubMed
28.
Zurück zum Zitat Kofinas AD, Simon NV, Sagel H, et al.: Treatment of fetal supraventricular tachycardia with flecainide acetate after digoxin failure. Am J Obstet Gynecol 1991, 165:630.PubMed Kofinas AD, Simon NV, Sagel H, et al.: Treatment of fetal supraventricular tachycardia with flecainide acetate after digoxin failure. Am J Obstet Gynecol 1991, 165:630.PubMed
29.
Zurück zum Zitat Ahmed K, Issawi I, Peddireddy R: Use of flecainide for refractory atrial tachycardia of pregnancy. Am J Crit Care 1996, 5:306.PubMed Ahmed K, Issawi I, Peddireddy R: Use of flecainide for refractory atrial tachycardia of pregnancy. Am J Crit Care 1996, 5:306.PubMed
30.
Zurück zum Zitat MacNeil DJ: The side effect profile of class III antiarrhythmic drugs: focus on d, l-sotalol. Am J Cardiol 1997, 80:90G.CrossRefPubMed MacNeil DJ: The side effect profile of class III antiarrhythmic drugs: focus on d, l-sotalol. Am J Cardiol 1997, 80:90G.CrossRefPubMed
31.
Zurück zum Zitat Magee LA, Downar E, Sermer M, et al.: Pregnancy outcome after gestational exposure to amiodarone in Canada. Am J Obstet Gynecol 1995, 172:1307.CrossRefPubMed Magee LA, Downar E, Sermer M, et al.: Pregnancy outcome after gestational exposure to amiodarone in Canada. Am J Obstet Gynecol 1995, 172:1307.CrossRefPubMed
32.
Zurück zum Zitat Ovadia M, Brito M, Hoyer GL, et al.: Human experience with amiodarone in the embryonic period. Am J Cardiol 1994, 73:316.CrossRefPubMed Ovadia M, Brito M, Hoyer GL, et al.: Human experience with amiodarone in the embryonic period. Am J Cardiol 1994, 73:316.CrossRefPubMed
33.••
Zurück zum Zitat Strasburger JF, Cuneo BF, Michon MM, et al.: Amiodarone therapy for drug-refractory fetal tachycardia. Circulation 2004, 109:375–379.CrossRefPubMed Strasburger JF, Cuneo BF, Michon MM, et al.: Amiodarone therapy for drug-refractory fetal tachycardia. Circulation 2004, 109:375–379.CrossRefPubMed
34.
35.
Zurück zum Zitat Kockova R, Kocka V, Kiernan T, et al.: Ibutilide-induced cardioversion of atrial fibrillation during pregnancy. J Cardiovasc Electrophysiol 2007, 18:545–547.CrossRefPubMed Kockova R, Kocka V, Kiernan T, et al.: Ibutilide-induced cardioversion of atrial fibrillation during pregnancy. J Cardiovasc Electrophysiol 2007, 18:545–547.CrossRefPubMed
36.
Zurück zum Zitat Burkart TA, Kron J, Miles WM, et al.: Successful termination of atrial flutter by ibutilide during pregnancy. Pacing Clin Electrophysiol 2007, 30:283–286.CrossRefPubMed Burkart TA, Kron J, Miles WM, et al.: Successful termination of atrial flutter by ibutilide during pregnancy. Pacing Clin Electrophysiol 2007, 30:283–286.CrossRefPubMed
37.
Zurück zum Zitat Ogburn P, Schmidt G, Linman J, et al.: Paroxysmal tachycardia and cardioversion during pregnancy. J Reprod Med 1982, 27:359–362.PubMed Ogburn P, Schmidt G, Linman J, et al.: Paroxysmal tachycardia and cardioversion during pregnancy. J Reprod Med 1982, 27:359–362.PubMed
38.
Zurück zum Zitat Curry JJ, Quintana FJ: Myocardial infarction with ventricular fibrillation during pregnancy treated by direct current defibrillation with fetal survival. Chest 1970, 58:82.CrossRefPubMed Curry JJ, Quintana FJ: Myocardial infarction with ventricular fibrillation during pregnancy treated by direct current defibrillation with fetal survival. Chest 1970, 58:82.CrossRefPubMed
39.
Zurück zum Zitat Barnes EJ, Eben F, Patterson D: Direct current cardioversion during pregnancy should be performed with facilities available for fetal monitoring and emergency caesarean section. BJOG 2002, 109:1406–1407.CrossRefPubMed Barnes EJ, Eben F, Patterson D: Direct current cardioversion during pregnancy should be performed with facilities available for fetal monitoring and emergency caesarean section. BJOG 2002, 109:1406–1407.CrossRefPubMed
40.
Zurück zum Zitat Chandra NC, Gates EA, Thamer M: Conservative treatment of paroxysmal ventricular tachycardia during pregnancy. Clin Cardiol 1991, 14:347.CrossRefPubMed Chandra NC, Gates EA, Thamer M: Conservative treatment of paroxysmal ventricular tachycardia during pregnancy. Clin Cardiol 1991, 14:347.CrossRefPubMed
41.
Zurück zum Zitat Brodsky M, Doria R, Allen B, et al.: New-onset ventricular tachycardia during pregnancy. Am Heart J 1992, 123:933.CrossRefPubMed Brodsky M, Doria R, Allen B, et al.: New-onset ventricular tachycardia during pregnancy. Am Heart J 1992, 123:933.CrossRefPubMed
42.•
Zurück zum Zitat Seth R, Moss AJ, McNitt S, et al.: Long QT syndrome and pregnancy. J Am Coll Cardiol 2007, 49:1092–1098.CrossRefPubMed Seth R, Moss AJ, McNitt S, et al.: Long QT syndrome and pregnancy. J Am Coll Cardiol 2007, 49:1092–1098.CrossRefPubMed
43.
Zurück zum Zitat Briggs GG, Freeman RK, Yaffe SJ: Drugs in Pregnancy and Lactation, edn 5th. Baltimore: Williams & Wilkins; 1998. Briggs GG, Freeman RK, Yaffe SJ: Drugs in Pregnancy and Lactation, edn 5th. Baltimore: Williams & Wilkins; 1998.
44.
Zurück zum Zitat American Heart Association and the International Liaison Committee on Resuscitation: Guidelines 2000 for cardiopulmonary resuscitation and emergency cardiovascular care. Part 8: Advanced challenges in resuscitation. Section 3: Special challenges in ECC. 3F: Cardiac arrest associated with pregnancy. Circulation 2000, 102(suppl 8):I247. American Heart Association and the International Liaison Committee on Resuscitation: Guidelines 2000 for cardiopulmonary resuscitation and emergency cardiovascular care. Part 8: Advanced challenges in resuscitation. Section 3: Special challenges in ECC. 3F: Cardiac arrest associated with pregnancy. Circulation 2000, 102(suppl 8):I247.
45.
Zurück zum Zitat Kileff MB, James 3rd FM, Dewan D, et al.: Neonatal neurobehavioral responses after epidural anesthesia for cesarean section with lidocaine and bupivacaine. Anesthesiology 1983, 57:A403.CrossRef Kileff MB, James 3rd FM, Dewan D, et al.: Neonatal neurobehavioral responses after epidural anesthesia for cesarean section with lidocaine and bupivacaine. Anesthesiology 1983, 57:A403.CrossRef
46.
Zurück zum Zitat Fagih B, Sami M: Safety of antiarrhythmics during pregnancy: case report and review of the literature. Can J Cardiol 1999, 15:113.PubMed Fagih B, Sami M: Safety of antiarrhythmics during pregnancy: case report and review of the literature. Can J Cardiol 1999, 15:113.PubMed
47.
Zurück zum Zitat Natale A, Davidson T, Geiger MJ, Newby K: Implantable cardioverter-defibrillators and pregnancy. A safe combination? Circulation 1997, 96:2808–2812.PubMed Natale A, Davidson T, Geiger MJ, Newby K: Implantable cardioverter-defibrillators and pregnancy. A safe combination? Circulation 1997, 96:2808–2812.PubMed
48.
Zurück zum Zitat Kloeck W, Cummins RO, Chamberlain D, et al.: Special resuscitation situations: an advisory statement from the International Liaison Committee on Resuscitation. Circulation 1997, 95:2196.PubMed Kloeck W, Cummins RO, Chamberlain D, et al.: Special resuscitation situations: an advisory statement from the International Liaison Committee on Resuscitation. Circulation 1997, 95:2196.PubMed
49.
Zurück zum Zitat Whitty J: Maternal cardiac arrest in pregnancy. Clin Obstet Gynecol 2002, 245;2:574. Whitty J: Maternal cardiac arrest in pregnancy. Clin Obstet Gynecol 2002, 245;2:574.
50.
Zurück zum Zitat Kerr MG, Scott DB, Samuel E: Studies of the inferior vena cava in late pregnancy. BMJ 1964, 1:532.PubMed Kerr MG, Scott DB, Samuel E: Studies of the inferior vena cava in late pregnancy. BMJ 1964, 1:532.PubMed
51.
Zurück zum Zitat Goodwin AP, Pearce AJ: The human wedge. A manoeuvre to relieve aortocaval compression during resuscitation in late pregnancy. Anaesthesia 1992, 47:433.CrossRefPubMed Goodwin AP, Pearce AJ: The human wedge. A manoeuvre to relieve aortocaval compression during resuscitation in late pregnancy. Anaesthesia 1992, 47:433.CrossRefPubMed
52.••
Zurück zum Zitat 2005 American Heart Association guidelines of cardiopulmonary resuscitation and emergency cardiovascular care. Part 10.8: cardiac arrest associated with pregnancy. Circulation 2005, 112(Suppl 1):IV-150–IV-153. These are the latest published ACLS guidelines. Part 10.8 specifically addresses performing ACLS on the pregnant patient. 2005 American Heart Association guidelines of cardiopulmonary resuscitation and emergency cardiovascular care. Part 10.8: cardiac arrest associated with pregnancy. Circulation 2005, 112(Suppl 1):IV-150–IV-153. These are the latest published ACLS guidelines. Part 10.8 specifically addresses performing ACLS on the pregnant patient.
54.
Zurück zum Zitat Ginsberg JS, Greer I, Hirsh J: Use of antithrombotic agents during pregnancy. Chest 2001, 119:122S.CrossRefPubMed Ginsberg JS, Greer I, Hirsh J: Use of antithrombotic agents during pregnancy. Chest 2001, 119:122S.CrossRefPubMed
55.
Zurück zum Zitat Anticoagulation in Prosthetic Valves and Pregnancy Consensus Report (APPCR) panel and scientific roundtable. Anticoagulation and enoxaparin use in patients with prosthetic heart valves and/or pregnancy, Topol EJ, Chairman. Clin Cardiol Consensus Rep 2002, 1-20. Anticoagulation in Prosthetic Valves and Pregnancy Consensus Report (APPCR) panel and scientific roundtable. Anticoagulation and enoxaparin use in patients with prosthetic heart valves and/or pregnancy, Topol EJ, Chairman. Clin Cardiol Consensus Rep 2002, 1-20.
56.
Zurück zum Zitat Huxtable LM, Tafreshi MJ, Ondreyco SM: A protocol for the use of enoxaparin during pregnancy: results from 85 pregnancies including 13 multiple gestation pregnancies. Clin Appl Thromb Hemost 2005, 11:171CrossRefPubMed Huxtable LM, Tafreshi MJ, Ondreyco SM: A protocol for the use of enoxaparin during pregnancy: results from 85 pregnancies including 13 multiple gestation pregnancies. Clin Appl Thromb Hemost 2005, 11:171CrossRefPubMed
57.
Zurück zum Zitat Spritzer RC, Seldon M, Mattes LM, et al.: Serious arrhythmias during labor and delivery in women with heart disease. JAMA 1005, 1970:211. Spritzer RC, Seldon M, Mattes LM, et al.: Serious arrhythmias during labor and delivery in women with heart disease. JAMA 1005, 1970:211.
58.
Zurück zum Zitat Physicians’ Desk Reference: PDR. edn. 55. Oradell, NJ: Medical Economics; 2001:344. Physicians’ Desk Reference: PDR. edn. 55. Oradell, NJ: Medical Economics; 2001:344.
Metadaten
Titel
Cardiac Arrhythmias During Pregnancy
verfasst von
Thomas Adam Burkart, MD
Jamie Beth Conti, MD
Publikationsdatum
01.10.2010
Verlag
Current Science Inc.
Erschienen in
Current Treatment Options in Cardiovascular Medicine / Ausgabe 5/2010
Print ISSN: 1092-8464
Elektronische ISSN: 1534-3189
DOI
https://doi.org/10.1007/s11936-010-0084-7

Weitere Artikel der Ausgabe 5/2010

Current Treatment Options in Cardiovascular Medicine 5/2010 Zur Ausgabe

Die „Zehn Gebote“ des Endokarditis-Managements

30.04.2024 Endokarditis Leitlinie kompakt

Worauf kommt es beim Management von Personen mit infektiöser Endokarditis an? Eine Kardiologin und ein Kardiologe fassen die zehn wichtigsten Punkte der neuen ESC-Leitlinie zusammen.

Strenge Blutdruckeinstellung lohnt auch im Alter noch

30.04.2024 Arterielle Hypertonie Nachrichten

Ältere Frauen, die von chronischen Erkrankungen weitgehend verschont sind, haben offenbar die besten Chancen, ihren 90. Geburtstag zu erleben, wenn ihr systolischer Blutdruck < 130 mmHg liegt. Das scheint selbst für 80-Jährige noch zu gelten.

Sind Frauen die fähigeren Ärzte?

30.04.2024 Gendermedizin Nachrichten

Patienten, die von Ärztinnen behandelt werden, dürfen offenbar auf bessere Therapieergebnisse hoffen als Patienten von Ärzten. Besonders gilt das offenbar für weibliche Kranke, wie eine Studie zeigt.

Dihydropyridin-Kalziumantagonisten können auf die Nieren gehen

30.04.2024 Hypertonie Nachrichten

Im Vergleich zu anderen Blutdrucksenkern sind Kalziumantagonisten vom Diyhdropyridin-Typ mit einem erhöhten Risiko für eine Mikroalbuminurie und in Abwesenheit eines RAS-Blockers auch für ein terminales Nierenversagen verbunden.

Update Kardiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.