Skip to main content
Erschienen in: Current Atherosclerosis Reports 5/2016

01.05.2016 | Cardiovascular Disease and Stroke (S. Prabhakaran, Section Editor)

Cardiac MRI and Ischemic Heart Disease: Role in Diagnosis and Risk Stratification

verfasst von: Rahul N. Sawlani, Jeremy D. Collins

Erschienen in: Current Atherosclerosis Reports | Ausgabe 5/2016

Einloggen, um Zugang zu erhalten

Abstract

Cardiac magnetic resonance imaging (CMRI) has been under development for the past four decades and has more recently become an essential tool in the evaluation of ischemic heart disease (IHD). It is the reference standard for quantification of both right and left ventricular volume and function and, after landmark work published in the New England Journal of Medicine in 2000, has proven effective in identifying hibernating myocardium, or hypokinetic myocardium that will recover after revascularization. More recent literature continues to support both delayed enhancement imaging and CMRI stress perfusion as essential tools in evaluating IHD. This review will briefly address the basics of CMRI and the scientific literature supporting the use of CMRI in IHD. It will then address more recent clinical studies establishing the clinical utility of CMRI in IHD, followed by a discussion of future directions in CMRI.
Literatur
1.
Zurück zum Zitat Pohost GM. The history of cardiovascular magnetic resonance. JACC Cardiovasc Imaging. 2008;1(5):672–8.CrossRefPubMed Pohost GM. The history of cardiovascular magnetic resonance. JACC Cardiovasc Imaging. 2008;1(5):672–8.CrossRefPubMed
2.
Zurück zum Zitat Semelka RC et al. Normal left ventricular dimensions and function: interstudy reproducibility of measurements with cine MR imaging. Radiology. 1990;174(3 Pt 1):763–8.CrossRefPubMed Semelka RC et al. Normal left ventricular dimensions and function: interstudy reproducibility of measurements with cine MR imaging. Radiology. 1990;174(3 Pt 1):763–8.CrossRefPubMed
3.
Zurück zum Zitat Barkhausen J et al. MR evaluation of ventricular function: true fast imaging with steady-state precession versus fast low-angle shot cine MR imaging: feasibility study. Radiology. 2001;219(1):264–9.CrossRefPubMed Barkhausen J et al. MR evaluation of ventricular function: true fast imaging with steady-state precession versus fast low-angle shot cine MR imaging: feasibility study. Radiology. 2001;219(1):264–9.CrossRefPubMed
4.
Zurück zum Zitat Grothues F et al. Comparison of interstudy reproducibility of cardiovascular magnetic resonance with two-dimensional echocardiography in normal subjects and in patients with heart failure or left ventricular hypertrophy. Am J Cardiol. 2002;90(1):29–34.CrossRefPubMed Grothues F et al. Comparison of interstudy reproducibility of cardiovascular magnetic resonance with two-dimensional echocardiography in normal subjects and in patients with heart failure or left ventricular hypertrophy. Am J Cardiol. 2002;90(1):29–34.CrossRefPubMed
5.
Zurück zum Zitat Kim RJ et al. The use of contrast-enhanced magnetic resonance imaging to identify reversible myocardial dysfunction. N Engl J Med. 2000;343(20):1445–53.CrossRefPubMed Kim RJ et al. The use of contrast-enhanced magnetic resonance imaging to identify reversible myocardial dysfunction. N Engl J Med. 2000;343(20):1445–53.CrossRefPubMed
6.
Zurück zum Zitat Atkinson DJ, Edelman RR. Cineangiography of the heart in a single breath hold with a segmented turboFLASH sequence. Radiology. 1991;178(2):357–60.CrossRefPubMed Atkinson DJ, Edelman RR. Cineangiography of the heart in a single breath hold with a segmented turboFLASH sequence. Radiology. 1991;178(2):357–60.CrossRefPubMed
7.
Zurück zum Zitat Edelman RR et al. Segmented turboFLASH: method for breath-hold MR imaging of the liver with flexible contrast. Radiology. 1990;177(2):515–21.CrossRefPubMed Edelman RR et al. Segmented turboFLASH: method for breath-hold MR imaging of the liver with flexible contrast. Radiology. 1990;177(2):515–21.CrossRefPubMed
8.
Zurück zum Zitat Simonetti OP et al. An improved MR imaging technique for the visualization of myocardial infarction. Radiology. 2001;218(1):215–23.CrossRefPubMed Simonetti OP et al. An improved MR imaging technique for the visualization of myocardial infarction. Radiology. 2001;218(1):215–23.CrossRefPubMed
9.
Zurück zum Zitat Huber AM et al. Phase-sensitive inversion-recovery MR imaging in the detection of myocardial infarction. Radiology. 2005;237(3):854–60.CrossRefPubMed Huber AM et al. Phase-sensitive inversion-recovery MR imaging in the detection of myocardial infarction. Radiology. 2005;237(3):854–60.CrossRefPubMed
10.
Zurück zum Zitat Li W et al. Myocardial delayed enhancement imaging using inversion recovery single-shot steady-state free precession: initial experience. J Magn Reson Imaging. 2004;20(2):327–30.CrossRefPubMed Li W et al. Myocardial delayed enhancement imaging using inversion recovery single-shot steady-state free precession: initial experience. J Magn Reson Imaging. 2004;20(2):327–30.CrossRefPubMed
11.
Zurück zum Zitat Bruder O et al. Update on acute adverse reactions to gadolinium based contrast agents in cardiovascular MR. Large multi-national and multi-ethnical population experience with 37788 patients from the EuroCMR Registry. J Cardiovasc Magn Reson. 2015;17:58.CrossRefPubMedPubMedCentral Bruder O et al. Update on acute adverse reactions to gadolinium based contrast agents in cardiovascular MR. Large multi-national and multi-ethnical population experience with 37788 patients from the EuroCMR Registry. J Cardiovasc Magn Reson. 2015;17:58.CrossRefPubMedPubMedCentral
12.
Zurück zum Zitat Expert Panel on, M.R.S et al. ACR guidance document on MR safe practices. J Magn Reson Imaging. 2013;37(3):501–30.CrossRef Expert Panel on, M.R.S et al. ACR guidance document on MR safe practices. J Magn Reson Imaging. 2013;37(3):501–30.CrossRef
13.
Zurück zum Zitat Shellock FG, Spinazzi A. MRI safety update 2008: part 2, screening patients for MRI. AJR Am J Roentgenol. 2008;191(4):1140–9.CrossRefPubMed Shellock FG, Spinazzi A. MRI safety update 2008: part 2, screening patients for MRI. AJR Am J Roentgenol. 2008;191(4):1140–9.CrossRefPubMed
14.
Zurück zum Zitat Nazarian S et al. Clinical utility and safety of a protocol for noncardiac and cardiac magnetic resonance imaging of patients with permanent pacemakers and implantable-cardioverter defibrillators at 1.5 tesla. Circulation. 2006;114(12):1277–84.CrossRefPubMedPubMedCentral Nazarian S et al. Clinical utility and safety of a protocol for noncardiac and cardiac magnetic resonance imaging of patients with permanent pacemakers and implantable-cardioverter defibrillators at 1.5 tesla. Circulation. 2006;114(12):1277–84.CrossRefPubMedPubMedCentral
15.
Zurück zum Zitat Bruder O et al. European Cardiovascular Magnetic Resonance (EuroCMR) registry—multi national results from 57 centers in 15 countries. J Cardiovasc Magn Reson. 2013;15:9.CrossRefPubMedPubMedCentral Bruder O et al. European Cardiovascular Magnetic Resonance (EuroCMR) registry—multi national results from 57 centers in 15 countries. J Cardiovasc Magn Reson. 2013;15:9.CrossRefPubMedPubMedCentral
16.
Zurück zum Zitat Kanda T et al. High signal intensity in the dentate nucleus and globus pallidus on unenhanced T1-weighted MR images: relationship with increasing cumulative dose of a gadolinium-based contrast material. Radiology. 2014;270(3):834–41.CrossRefPubMed Kanda T et al. High signal intensity in the dentate nucleus and globus pallidus on unenhanced T1-weighted MR images: relationship with increasing cumulative dose of a gadolinium-based contrast material. Radiology. 2014;270(3):834–41.CrossRefPubMed
17.
Zurück zum Zitat Kanda T et al. Gadolinium-based contrast agent accumulates in the brain even in subjects without severe renal dysfunction: evaluation of autopsy brain specimens with inductively coupled plasma mass spectroscopy. Radiology. 2015;276(1):228–32.CrossRefPubMed Kanda T et al. Gadolinium-based contrast agent accumulates in the brain even in subjects without severe renal dysfunction: evaluation of autopsy brain specimens with inductively coupled plasma mass spectroscopy. Radiology. 2015;276(1):228–32.CrossRefPubMed
18.
Zurück zum Zitat Kanda T et al. High signal intensity in dentate nucleus on unenhanced T1-weighted MR images: association with linear versus macrocyclic gadolinium chelate administration. Radiology. 2015;275(3):803–9.CrossRefPubMed Kanda T et al. High signal intensity in dentate nucleus on unenhanced T1-weighted MR images: association with linear versus macrocyclic gadolinium chelate administration. Radiology. 2015;275(3):803–9.CrossRefPubMed
19.
Zurück zum Zitat Radbruch A et al. Gadolinium retention in the dentate nucleus and globus pallidus is dependent on the class of contrast agent. Radiology. 2015;275(3):783–91.CrossRefPubMed Radbruch A et al. Gadolinium retention in the dentate nucleus and globus pallidus is dependent on the class of contrast agent. Radiology. 2015;275(3):783–91.CrossRefPubMed
20.
Zurück zum Zitat Acc/Aha/Esc. [ACC/AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden death]. Kardiologiia. 2011;51(7):65–96. Acc/Aha/Esc. [ACC/AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden death]. Kardiologiia. 2011;51(7):65–96.
21.
Zurück zum Zitat Hunt SA et al. 2009 Focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults. A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines developed in collaboration with the International Society for Heart and Lung Transplantation. J Am Coll Cardiol. 2009;53(15):e1–90.CrossRefPubMed Hunt SA et al. 2009 Focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults. A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines developed in collaboration with the International Society for Heart and Lung Transplantation. J Am Coll Cardiol. 2009;53(15):e1–90.CrossRefPubMed
22.
Zurück zum Zitat Mooij CF et al. Reproducibility of MRI measurements of right ventricular size and function in patients with normal and dilated ventricles. J Magn Reson Imaging. 2008;28(1):67–73.CrossRefPubMedPubMedCentral Mooij CF et al. Reproducibility of MRI measurements of right ventricular size and function in patients with normal and dilated ventricles. J Magn Reson Imaging. 2008;28(1):67–73.CrossRefPubMedPubMedCentral
23.
Zurück zum Zitat Larose E et al. Right ventricular dysfunction assessed by cardiovascular magnetic resonance imaging predicts poor prognosis late after myocardial infarction. J Am Coll Cardiol. 2007;49(8):855–62.CrossRefPubMed Larose E et al. Right ventricular dysfunction assessed by cardiovascular magnetic resonance imaging predicts poor prognosis late after myocardial infarction. J Am Coll Cardiol. 2007;49(8):855–62.CrossRefPubMed
24.
Zurück zum Zitat Miszalski-Jamka T et al. Extent of RV dysfunction and myocardial infarction assessed by CMR are independent outcome predictors early after STEMI treated with primary angioplasty. JACC Cardiovasc Imaging. 2010;3(12):1237–46.CrossRefPubMed Miszalski-Jamka T et al. Extent of RV dysfunction and myocardial infarction assessed by CMR are independent outcome predictors early after STEMI treated with primary angioplasty. JACC Cardiovasc Imaging. 2010;3(12):1237–46.CrossRefPubMed
25.
Zurück zum Zitat Rahimtoola SH. A perspective on the three large multicenter randomized clinical trials of coronary bypass surgery for chronic stable angina. Circulation. 1985;72(6 Pt 2):V123–35.PubMed Rahimtoola SH. A perspective on the three large multicenter randomized clinical trials of coronary bypass surgery for chronic stable angina. Circulation. 1985;72(6 Pt 2):V123–35.PubMed
26.
Zurück zum Zitat Vanoverschelde JL et al. Mechanisms of chronic regional postischemic dysfunction in humans. New insights from the study of noninfarcted collateral-dependent myocardium. Circulation. 1993;87(5):1513–23.CrossRefPubMed Vanoverschelde JL et al. Mechanisms of chronic regional postischemic dysfunction in humans. New insights from the study of noninfarcted collateral-dependent myocardium. Circulation. 1993;87(5):1513–23.CrossRefPubMed
27.
28.
Zurück zum Zitat Selvanayagam JB et al. Resting myocardial blood flow is impaired in hibernating myocardium: a magnetic resonance study of quantitative perfusion assessment. Circulation. 2005;112(21):3289–96.CrossRefPubMed Selvanayagam JB et al. Resting myocardial blood flow is impaired in hibernating myocardium: a magnetic resonance study of quantitative perfusion assessment. Circulation. 2005;112(21):3289–96.CrossRefPubMed
29.
Zurück zum Zitat Choi KM et al. Transmural extent of acute myocardial infarction predicts long-term improvement in contractile function. Circulation. 2001;104(10):1101–7.CrossRefPubMed Choi KM et al. Transmural extent of acute myocardial infarction predicts long-term improvement in contractile function. Circulation. 2001;104(10):1101–7.CrossRefPubMed
30.
Zurück zum Zitat Cheong BY et al. Prognostic significance of delayed-enhancement magnetic resonance imaging: survival of 857 patients with and without left ventricular dysfunction. Circulation. 2009;120(21):2069–76.CrossRefPubMed Cheong BY et al. Prognostic significance of delayed-enhancement magnetic resonance imaging: survival of 857 patients with and without left ventricular dysfunction. Circulation. 2009;120(21):2069–76.CrossRefPubMed
31.
Zurück zum Zitat Bingham SE, Hachamovitch R. Incremental prognostic significance of combined cardiac magnetic resonance imaging, adenosine stress perfusion, delayed enhancement, and left ventricular function over preimaging information for the prediction of adverse events. Circulation. 2011;123(14):1509–18.CrossRefPubMed Bingham SE, Hachamovitch R. Incremental prognostic significance of combined cardiac magnetic resonance imaging, adenosine stress perfusion, delayed enhancement, and left ventricular function over preimaging information for the prediction of adverse events. Circulation. 2011;123(14):1509–18.CrossRefPubMed
33.
Zurück zum Zitat Schuster A et al. Imaging in the management of ischemic cardiomyopathy: special focus on magnetic resonance. J Am Coll Cardiol. 2012;59(4):359–70.CrossRefPubMed Schuster A et al. Imaging in the management of ischemic cardiomyopathy: special focus on magnetic resonance. J Am Coll Cardiol. 2012;59(4):359–70.CrossRefPubMed
34.
Zurück zum Zitat Camici PG, Prasad SK, Rimoldi OE. Stunning, hibernation, and assessment of myocardial viability. Circulation. 2008;117(1):103–14.CrossRefPubMed Camici PG, Prasad SK, Rimoldi OE. Stunning, hibernation, and assessment of myocardial viability. Circulation. 2008;117(1):103–14.CrossRefPubMed
35.
Zurück zum Zitat Kim RJ. Fundamental concepts in myocardial viability assessment revisited: when knowing how much is “alive” is not enough. Heart. 2004;90(2):137–40.CrossRefPubMedPubMedCentral Kim RJ. Fundamental concepts in myocardial viability assessment revisited: when knowing how much is “alive” is not enough. Heart. 2004;90(2):137–40.CrossRefPubMedPubMedCentral
36.
Zurück zum Zitat Pfeffer MA, Braunwald E. Ventricular remodeling after myocardial infarction. Experimental observations and clinical implications. Circulation. 1990;81(4):1161–72.CrossRefPubMed Pfeffer MA, Braunwald E. Ventricular remodeling after myocardial infarction. Experimental observations and clinical implications. Circulation. 1990;81(4):1161–72.CrossRefPubMed
37.
Zurück zum Zitat Fieno DS et al. Infarct resorption, compensatory hypertrophy, and differing patterns of ventricular remodeling following myocardial infarctions of varying size. J Am Coll Cardiol. 2004;43(11):2124–31.CrossRefPubMed Fieno DS et al. Infarct resorption, compensatory hypertrophy, and differing patterns of ventricular remodeling following myocardial infarctions of varying size. J Am Coll Cardiol. 2004;43(11):2124–31.CrossRefPubMed
38.
Zurück zum Zitat John AS, Dreyfus GD, Pennell DJ. Images in cardiovascular medicine. Reversible wall thinning in hibernation predicted by cardiovascular magnetic resonance. Circulation. 2005;111(3):e24–5.CrossRefPubMed John AS, Dreyfus GD, Pennell DJ. Images in cardiovascular medicine. Reversible wall thinning in hibernation predicted by cardiovascular magnetic resonance. Circulation. 2005;111(3):e24–5.CrossRefPubMed
39.••
Zurück zum Zitat Shah DJ et al. Prevalence of regional myocardial thinning and relationship with myocardial scarring in patients with coronary artery disease. JAMA. 2013;309(9):909–18. This trial demonstrates that myocardium can be viable despite myocardial thinning, and that viability is better assessed by transmurality of delayed enhancement than by wall thickness. It showed that segments demonstrating viability by delayed enhancement imaging tend to recover both function and wall thickness after revascularization.CrossRefPubMedPubMedCentral Shah DJ et al. Prevalence of regional myocardial thinning and relationship with myocardial scarring in patients with coronary artery disease. JAMA. 2013;309(9):909–18. This trial demonstrates that myocardium can be viable despite myocardial thinning, and that viability is better assessed by transmurality of delayed enhancement than by wall thickness. It showed that segments demonstrating viability by delayed enhancement imaging tend to recover both function and wall thickness after revascularization.CrossRefPubMedPubMedCentral
40.
Zurück zum Zitat Epstein AE et al. ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the ACC/AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices) developed in collaboration with the American Association for Thoracic Surgery and Society of Thoracic Surgeons. J Am Coll Cardiol. 2008;51(21):e1–62.CrossRefPubMed Epstein AE et al. ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the ACC/AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices) developed in collaboration with the American Association for Thoracic Surgery and Society of Thoracic Surgeons. J Am Coll Cardiol. 2008;51(21):e1–62.CrossRefPubMed
41.
Zurück zum Zitat Moss AJ et al. Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction. N Engl J Med. 2002;346(12):877–83.CrossRefPubMed Moss AJ et al. Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction. N Engl J Med. 2002;346(12):877–83.CrossRefPubMed
42.
Zurück zum Zitat Watanabe E et al. Infarct tissue heterogeneity by contrast-enhanced magnetic resonance imaging is a novel predictor of mortality in patients with chronic coronary artery disease and left ventricular dysfunction. Circ Cardiovasc Imaging. 2014;7(6):887–94.CrossRefPubMedPubMedCentral Watanabe E et al. Infarct tissue heterogeneity by contrast-enhanced magnetic resonance imaging is a novel predictor of mortality in patients with chronic coronary artery disease and left ventricular dysfunction. Circ Cardiovasc Imaging. 2014;7(6):887–94.CrossRefPubMedPubMedCentral
43.
Zurück zum Zitat Schmidt A et al. Infarct tissue heterogeneity by magnetic resonance imaging identifies enhanced cardiac arrhythmia susceptibility in patients with left ventricular dysfunction. Circulation. 2007;115(15):2006–14.CrossRefPubMedPubMedCentral Schmidt A et al. Infarct tissue heterogeneity by magnetic resonance imaging identifies enhanced cardiac arrhythmia susceptibility in patients with left ventricular dysfunction. Circulation. 2007;115(15):2006–14.CrossRefPubMedPubMedCentral
44.
Zurück zum Zitat Gao P et al. Prediction of arrhythmic events in ischemic and dilated cardiomyopathy patients referred for implantable cardiac defibrillator: evaluation of multiple scar quantification measures for late gadolinium enhancement magnetic resonance imaging. Circ Cardiovasc Imaging. 2012;5(4):448–56.CrossRefPubMed Gao P et al. Prediction of arrhythmic events in ischemic and dilated cardiomyopathy patients referred for implantable cardiac defibrillator: evaluation of multiple scar quantification measures for late gadolinium enhancement magnetic resonance imaging. Circ Cardiovasc Imaging. 2012;5(4):448–56.CrossRefPubMed
45.
Zurück zum Zitat Heiberg E et al. Automated quantification of myocardial infarction from MR images by accounting for partial volume effects: animal, phantom, and human study. Radiology. 2008;246(2):581–8.CrossRefPubMed Heiberg E et al. Automated quantification of myocardial infarction from MR images by accounting for partial volume effects: animal, phantom, and human study. Radiology. 2008;246(2):581–8.CrossRefPubMed
46.
Zurück zum Zitat Kim HW, Farzaneh-Far A, Kim RJ. Cardiovascular magnetic resonance in patients with myocardial infarction: current and emerging applications. J Am Coll Cardiol. 2009;55(1):1–16.CrossRefPubMed Kim HW, Farzaneh-Far A, Kim RJ. Cardiovascular magnetic resonance in patients with myocardial infarction: current and emerging applications. J Am Coll Cardiol. 2009;55(1):1–16.CrossRefPubMed
47.
Zurück zum Zitat Assomull RG et al. The role of cardiovascular magnetic resonance in patients presenting with chest pain, raised troponin, and unobstructed coronary arteries. Eur Heart J. 2007;28(10):1242–9.CrossRefPubMed Assomull RG et al. The role of cardiovascular magnetic resonance in patients presenting with chest pain, raised troponin, and unobstructed coronary arteries. Eur Heart J. 2007;28(10):1242–9.CrossRefPubMed
48.
Zurück zum Zitat Goitein O et al. Acute myocarditis: noninvasive evaluation with cardiac MRI and transthoracic echocardiography. AJR Am J Roentgenol. 2009;192(1):254–8.CrossRefPubMed Goitein O et al. Acute myocarditis: noninvasive evaluation with cardiac MRI and transthoracic echocardiography. AJR Am J Roentgenol. 2009;192(1):254–8.CrossRefPubMed
49.
Zurück zum Zitat Mitchell JH et al. Clinical features and usefulness of cardiac magnetic resonance imaging in assessing myocardial viability and prognosis in Takotsubo cardiomyopathy (transient left ventricular apical ballooning syndrome). Am J Cardiol. 2007;100(2):296–301.CrossRefPubMed Mitchell JH et al. Clinical features and usefulness of cardiac magnetic resonance imaging in assessing myocardial viability and prognosis in Takotsubo cardiomyopathy (transient left ventricular apical ballooning syndrome). Am J Cardiol. 2007;100(2):296–301.CrossRefPubMed
50.
Zurück zum Zitat Yelgec NS et al. Value of MRI in patients with a clinical suspicion of acute myocarditis. Eur Radiol. 2007;17(9):2211–7.CrossRefPubMed Yelgec NS et al. Value of MRI in patients with a clinical suspicion of acute myocarditis. Eur Radiol. 2007;17(9):2211–7.CrossRefPubMed
51.
Zurück zum Zitat Langhans B et al. Reproducibility of area at risk assessment in acute myocardial infarction by T1- and T2-mapping sequences in cardiac magnetic resonance imaging in comparison to Tc99m-sestamibi SPECT. Int J Cardiovasc Imaging. 2014;30(7):1357–63.CrossRefPubMed Langhans B et al. Reproducibility of area at risk assessment in acute myocardial infarction by T1- and T2-mapping sequences in cardiac magnetic resonance imaging in comparison to Tc99m-sestamibi SPECT. Int J Cardiovasc Imaging. 2014;30(7):1357–63.CrossRefPubMed
52.
Zurück zum Zitat Ugander M et al. Myocardial edema as detected by pre-contrast T1 and T2 CMR delineates area at risk associated with acute myocardial infarction. JACC Cardiovasc Imaging. 2012;5(6):596–603.CrossRefPubMedPubMedCentral Ugander M et al. Myocardial edema as detected by pre-contrast T1 and T2 CMR delineates area at risk associated with acute myocardial infarction. JACC Cardiovasc Imaging. 2012;5(6):596–603.CrossRefPubMedPubMedCentral
53.
Zurück zum Zitat Eitel I, Thiele H. CMR mapping techniques for myocardium at risk: next step into a bright future? JACC Cardiovasc Imaging. 2012;5(6):604–6.CrossRefPubMed Eitel I, Thiele H. CMR mapping techniques for myocardium at risk: next step into a bright future? JACC Cardiovasc Imaging. 2012;5(6):604–6.CrossRefPubMed
55.
Zurück zum Zitat American College of Cardiology Foundation Task Force on Expert Consensus, D et al. ACCF/ACR/AHA/NASCI/SCMR 2010 expert consensus document on cardiovascular magnetic resonance: a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents. J Am Coll Cardiol. 2010;55(23):2614–62.CrossRef American College of Cardiology Foundation Task Force on Expert Consensus, D et al. ACCF/ACR/AHA/NASCI/SCMR 2010 expert consensus document on cardiovascular magnetic resonance: a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents. J Am Coll Cardiol. 2010;55(23):2614–62.CrossRef
56.
Zurück zum Zitat Lockie T et al. High-resolution magnetic resonance myocardial perfusion imaging at 3.0-Tesla to detect hemodynamically significant coronary stenoses as determined by fractional flow reserve. J Am Coll Cardiol. 2011;57(1):70–5.CrossRefPubMed Lockie T et al. High-resolution magnetic resonance myocardial perfusion imaging at 3.0-Tesla to detect hemodynamically significant coronary stenoses as determined by fractional flow reserve. J Am Coll Cardiol. 2011;57(1):70–5.CrossRefPubMed
57.
Zurück zum Zitat Rieber J et al. Cardiac magnetic resonance perfusion imaging for the functional assessment of coronary artery disease: a comparison with coronary angiography and fractional flow reserve. Eur Heart J. 2006;27(12):1465–71.CrossRefPubMed Rieber J et al. Cardiac magnetic resonance perfusion imaging for the functional assessment of coronary artery disease: a comparison with coronary angiography and fractional flow reserve. Eur Heart J. 2006;27(12):1465–71.CrossRefPubMed
58.
Zurück zum Zitat Nagel E et al. Magnetic resonance perfusion measurements for the noninvasive detection of coronary artery disease. Circulation. 2003;108(4):432–7.CrossRefPubMed Nagel E et al. Magnetic resonance perfusion measurements for the noninvasive detection of coronary artery disease. Circulation. 2003;108(4):432–7.CrossRefPubMed
59.
Zurück zum Zitat Wahl A et al. Safety and feasibility of high-dose dobutamine-atropine stress cardiovascular magnetic resonance for diagnosis of myocardial ischaemia: experience in 1000 consecutive cases. Eur Heart J. 2004;25(14):1230–6.CrossRefPubMed Wahl A et al. Safety and feasibility of high-dose dobutamine-atropine stress cardiovascular magnetic resonance for diagnosis of myocardial ischaemia: experience in 1000 consecutive cases. Eur Heart J. 2004;25(14):1230–6.CrossRefPubMed
60.
Zurück zum Zitat Nagel E et al. Noninvasive diagnosis of ischemia-induced wall motion abnormalities with the use of high-dose dobutamine stress MRI: comparison with dobutamine stress echocardiography. Circulation. 1999;99(6):763–70.CrossRefPubMed Nagel E et al. Noninvasive diagnosis of ischemia-induced wall motion abnormalities with the use of high-dose dobutamine stress MRI: comparison with dobutamine stress echocardiography. Circulation. 1999;99(6):763–70.CrossRefPubMed
61.
Zurück zum Zitat Jahnke C et al. Gender-based prognostic value of pharmacological cardiac magnetic resonance stress testing: head-to-head comparison of adenosine perfusion and dobutamine wall motion imaging. Int J Cardiovasc Imaging. 2012;28(5):1087–98.CrossRefPubMed Jahnke C et al. Gender-based prognostic value of pharmacological cardiac magnetic resonance stress testing: head-to-head comparison of adenosine perfusion and dobutamine wall motion imaging. Int J Cardiovasc Imaging. 2012;28(5):1087–98.CrossRefPubMed
62.
Zurück zum Zitat Paetsch I et al. Comparison of dobutamine stress magnetic resonance, adenosine stress magnetic resonance, and adenosine stress magnetic resonance perfusion. Circulation. 2004;110(7):835–42.CrossRefPubMed Paetsch I et al. Comparison of dobutamine stress magnetic resonance, adenosine stress magnetic resonance, and adenosine stress magnetic resonance perfusion. Circulation. 2004;110(7):835–42.CrossRefPubMed
63.
Zurück zum Zitat Kelle S et al. Prognostic value of myocardial infarct size and contractile reserve using magnetic resonance imaging. J Am Coll Cardiol. 2009;54(19):1770–7.CrossRefPubMed Kelle S et al. Prognostic value of myocardial infarct size and contractile reserve using magnetic resonance imaging. J Am Coll Cardiol. 2009;54(19):1770–7.CrossRefPubMed
64.
Zurück zum Zitat Kim RJ, Manning WJ. Viability assessment by delayed enhancement cardiovascular magnetic resonance: will low-dose dobutamine dull the shine? Circulation. 2004;109(21):2476–9.CrossRefPubMed Kim RJ, Manning WJ. Viability assessment by delayed enhancement cardiovascular magnetic resonance: will low-dose dobutamine dull the shine? Circulation. 2004;109(21):2476–9.CrossRefPubMed
65.
Zurück zum Zitat Wellnhofer E et al. Magnetic resonance low-dose dobutamine test is superior to SCAR quantification for the prediction of functional recovery. Circulation. 2004;109(18):2172–4.CrossRefPubMed Wellnhofer E et al. Magnetic resonance low-dose dobutamine test is superior to SCAR quantification for the prediction of functional recovery. Circulation. 2004;109(18):2172–4.CrossRefPubMed
66.••
Zurück zum Zitat Schwitter J et al. MR-IMPACT II: Magnetic Resonance Imaging for Myocardial Perfusion Assessment in Coronary Artery Disease Trial: perfusion-cardiac magnetic resonance vs. single-photon emission computed tomography for the detection of coronary artery disease: a comparative multicentre, multivendor trial. Eur Heart J. 2013;34(10):775–81. MR-IMPACT II: Large prospective multi-center trial directly comparing stress perfusions imaging with magnetic resonance imaging (MRI) and single-photon emission computed tomography (SPECT).CrossRefPubMed Schwitter J et al. MR-IMPACT II: Magnetic Resonance Imaging for Myocardial Perfusion Assessment in Coronary Artery Disease Trial: perfusion-cardiac magnetic resonance vs. single-photon emission computed tomography for the detection of coronary artery disease: a comparative multicentre, multivendor trial. Eur Heart J. 2013;34(10):775–81. MR-IMPACT II: Large prospective multi-center trial directly comparing stress perfusions imaging with magnetic resonance imaging (MRI) and single-photon emission computed tomography (SPECT).CrossRefPubMed
67.••
Zurück zum Zitat Greenwood JP et al. Cardiovascular magnetic resonance and single-photon emission computed tomography for diagnosis of coronary heart disease (CE-MARC): a prospective trial. Lancet. 2012;379(9814):453–60. CE-MARC: Large prospective multi-center trial directly comparing stress perfusions imaging with magnetic resonance imaging (MRI) and single-photon emission computed tomography (SPECT). CE-MARC: Large prospective multi-center trial directly comparing stress perfusions imaging with magnetic resonance imaging (MRI) and single-photon emission computed tomography (SPECT).CrossRefPubMedPubMedCentral Greenwood JP et al. Cardiovascular magnetic resonance and single-photon emission computed tomography for diagnosis of coronary heart disease (CE-MARC): a prospective trial. Lancet. 2012;379(9814):453–60. CE-MARC: Large prospective multi-center trial directly comparing stress perfusions imaging with magnetic resonance imaging (MRI) and single-photon emission computed tomography (SPECT). CE-MARC: Large prospective multi-center trial directly comparing stress perfusions imaging with magnetic resonance imaging (MRI) and single-photon emission computed tomography (SPECT).CrossRefPubMedPubMedCentral
68.
Zurück zum Zitat Schwitter J et al. Superior diagnostic performance of perfusion-cardiovascular magnetic resonance versus SPECT to detect coronary artery disease: the secondary endpoints of the multicenter multivendor MR-IMPACT II (Magnetic Resonance Imaging for Myocardial Perfusion Assessment in Coronary Artery Disease Trial). J Cardiovasc Magn Reson. 2012;14:61.CrossRefPubMedPubMedCentral Schwitter J et al. Superior diagnostic performance of perfusion-cardiovascular magnetic resonance versus SPECT to detect coronary artery disease: the secondary endpoints of the multicenter multivendor MR-IMPACT II (Magnetic Resonance Imaging for Myocardial Perfusion Assessment in Coronary Artery Disease Trial). J Cardiovasc Magn Reson. 2012;14:61.CrossRefPubMedPubMedCentral
69.
Zurück zum Zitat de Jong MC et al. Diagnostic performance of stress myocardial perfusion imaging for coronary artery disease: a systematic review and meta-analysis. Eur Radiol. 2012;22(9):1881–95.CrossRefPubMedPubMedCentral de Jong MC et al. Diagnostic performance of stress myocardial perfusion imaging for coronary artery disease: a systematic review and meta-analysis. Eur Radiol. 2012;22(9):1881–95.CrossRefPubMedPubMedCentral
70.
Zurück zum Zitat Jaarsma C et al. Diagnostic performance of noninvasive myocardial perfusion imaging using single-photon emission computed tomography, cardiac magnetic resonance, and positron emission tomography imaging for the detection of obstructive coronary artery disease: a meta-analysis. J Am Coll Cardiol. 2012;59(19):1719–28.CrossRefPubMed Jaarsma C et al. Diagnostic performance of noninvasive myocardial perfusion imaging using single-photon emission computed tomography, cardiac magnetic resonance, and positron emission tomography imaging for the detection of obstructive coronary artery disease: a meta-analysis. J Am Coll Cardiol. 2012;59(19):1719–28.CrossRefPubMed
71.
Zurück zum Zitat Panting JR et al. Abnormal subendocardial perfusion in cardiac syndrome X detected by cardiovascular magnetic resonance imaging. N Engl J Med. 2002;346(25):1948–53.CrossRefPubMed Panting JR et al. Abnormal subendocardial perfusion in cardiac syndrome X detected by cardiovascular magnetic resonance imaging. N Engl J Med. 2002;346(25):1948–53.CrossRefPubMed
72.
Zurück zum Zitat Pazos-Lopez P et al. Value of CMR for the differential diagnosis of cardiac masses. JACC Cardiovasc Imaging. 2014;7(9):896–905.CrossRefPubMed Pazos-Lopez P et al. Value of CMR for the differential diagnosis of cardiac masses. JACC Cardiovasc Imaging. 2014;7(9):896–905.CrossRefPubMed
73.
Zurück zum Zitat Mollet NR et al. Visualization of ventricular thrombi with contrast-enhanced magnetic resonance imaging in patients with ischemic heart disease. Circulation. 2002;106(23):2873–6.CrossRefPubMed Mollet NR et al. Visualization of ventricular thrombi with contrast-enhanced magnetic resonance imaging in patients with ischemic heart disease. Circulation. 2002;106(23):2873–6.CrossRefPubMed
74.
Zurück zum Zitat Srichai MB et al. Clinical, imaging, and pathological characteristics of left ventricular thrombus: a comparison of contrast-enhanced magnetic resonance imaging, transthoracic echocardiography, and transesophageal echocardiography with surgical or pathological validation. Am Heart J. 2006;152(1):75–84.CrossRefPubMed Srichai MB et al. Clinical, imaging, and pathological characteristics of left ventricular thrombus: a comparison of contrast-enhanced magnetic resonance imaging, transthoracic echocardiography, and transesophageal echocardiography with surgical or pathological validation. Am Heart J. 2006;152(1):75–84.CrossRefPubMed
75.
Zurück zum Zitat Ohyama H et al. Comparison of magnetic resonance imaging and transesophageal echocardiography in detection of thrombus in the left atrial appendage. Stroke. 2003;34(10):2436–9.CrossRefPubMed Ohyama H et al. Comparison of magnetic resonance imaging and transesophageal echocardiography in detection of thrombus in the left atrial appendage. Stroke. 2003;34(10):2436–9.CrossRefPubMed
76.
Zurück zum Zitat Gjesdal O et al. Long axis strain by MRI and echocardiography in a postmyocardial infarct population. J Magn Reson Imaging. 2014;40(5):1247–51.CrossRefPubMed Gjesdal O et al. Long axis strain by MRI and echocardiography in a postmyocardial infarct population. J Magn Reson Imaging. 2014;40(5):1247–51.CrossRefPubMed
77.
Zurück zum Zitat Bree D et al. Low-dose dobutamine tissue-tagged magnetic resonance imaging with 3-dimensional strain analysis allows assessment of myocardial viability in patients with ischemic cardiomyopathy. Circulation. 2006;114(1 Suppl):I33–6.PubMedPubMedCentral Bree D et al. Low-dose dobutamine tissue-tagged magnetic resonance imaging with 3-dimensional strain analysis allows assessment of myocardial viability in patients with ischemic cardiomyopathy. Circulation. 2006;114(1 Suppl):I33–6.PubMedPubMedCentral
78.
Zurück zum Zitat Korosoglou G et al. Strain-encoded CMR for the detection of inducible ischemia during intermediate stress. JACC Cardiovasc Imaging. 2010;3(4):361–71.CrossRefPubMed Korosoglou G et al. Strain-encoded CMR for the detection of inducible ischemia during intermediate stress. JACC Cardiovasc Imaging. 2010;3(4):361–71.CrossRefPubMed
79.
Zurück zum Zitat Korosoglou G et al. Strain-encoded cardiac MRI as an adjunct for dobutamine stress testing: incremental value to conventional wall motion analysis. Circ Cardiovasc Imaging. 2009;2(2):132–40.CrossRefPubMedPubMedCentral Korosoglou G et al. Strain-encoded cardiac MRI as an adjunct for dobutamine stress testing: incremental value to conventional wall motion analysis. Circ Cardiovasc Imaging. 2009;2(2):132–40.CrossRefPubMedPubMedCentral
80.
Zurück zum Zitat Schuster A et al. Cardiovascular magnetic resonance myocardial feature tracking for quantitative viability assessment in ischemic cardiomyopathy. Int J Cardiol. 2013;166(2):413–20.CrossRefPubMed Schuster A et al. Cardiovascular magnetic resonance myocardial feature tracking for quantitative viability assessment in ischemic cardiomyopathy. Int J Cardiol. 2013;166(2):413–20.CrossRefPubMed
81.
Zurück zum Zitat Jogiya R et al. Validation of dynamic 3-dimensional whole heart magnetic resonance myocardial perfusion imaging against fractional flow reserve for the detection of significant coronary artery disease. J Am Coll Cardiol. 2012;60(8):756–65.CrossRefPubMed Jogiya R et al. Validation of dynamic 3-dimensional whole heart magnetic resonance myocardial perfusion imaging against fractional flow reserve for the detection of significant coronary artery disease. J Am Coll Cardiol. 2012;60(8):756–65.CrossRefPubMed
82.
Zurück zum Zitat Lee DC, Johnson NP. Quantification of absolute myocardial blood flow by magnetic resonance perfusion imaging. JACC Cardiovasc Imaging. 2009;2(6):761–70.CrossRefPubMed Lee DC, Johnson NP. Quantification of absolute myocardial blood flow by magnetic resonance perfusion imaging. JACC Cardiovasc Imaging. 2009;2(6):761–70.CrossRefPubMed
Metadaten
Titel
Cardiac MRI and Ischemic Heart Disease: Role in Diagnosis and Risk Stratification
verfasst von
Rahul N. Sawlani
Jeremy D. Collins
Publikationsdatum
01.05.2016
Verlag
Springer US
Erschienen in
Current Atherosclerosis Reports / Ausgabe 5/2016
Print ISSN: 1523-3804
Elektronische ISSN: 1534-6242
DOI
https://doi.org/10.1007/s11883-016-0576-3

Weitere Artikel der Ausgabe 5/2016

Current Atherosclerosis Reports 5/2016 Zur Ausgabe

Coronary Heart Disease (S. Virani and S. Naderi, Section Editors)

Cardiorespiratory Fitness and Atherosclerosis: Recent Data and Future Directions

Vascular Biology (J. Hamilton, Section Editor)

Speciated High-Density Lipoprotein Biogenesis and Functionality

Coronary Heart Disease (S. Virani and S. Naderi, Section Editors)

Obesity and Cardiovascular Disease: a Risk Factor or a Risk Marker?

Cardiovascular Disease and Stroke (S. Prabhakaran, Section Editor)

Approach to Statin Use in 2016: an Update

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Notfall-TEP der Hüfte ist auch bei 90-Jährigen machbar

26.04.2024 Hüft-TEP Nachrichten

Ob bei einer Notfalloperation nach Schenkelhalsfraktur eine Hemiarthroplastik oder eine totale Endoprothese (TEP) eingebaut wird, sollte nicht allein vom Alter der Patientinnen und Patienten abhängen. Auch über 90-Jährige können von der TEP profitieren.

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

25.04.2024 Hypotonie Nachrichten

Wenn unter einer medikamentösen Hochdrucktherapie der diastolische Blutdruck in den Keller geht, steigt das Risiko für schwere kardiovaskuläre Ereignisse: Darauf deutet eine Sekundäranalyse der SPRINT-Studie hin.

Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

Insektenstiche sind bei Erwachsenen die häufigsten Auslöser einer Anaphylaxie. Einen wirksamen Schutz vor schweren anaphylaktischen Reaktionen bietet die allergenspezifische Immuntherapie. Jedoch kommt sie noch viel zu selten zum Einsatz.

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

25.04.2024 Hypertonie Nachrichten

Beginnen ältere Männer im Pflegeheim eine Antihypertensiva-Therapie, dann ist die Frakturrate in den folgenden 30 Tagen mehr als verdoppelt. Besonders häufig stürzen Demenzkranke und Männer, die erstmals Blutdrucksenker nehmen. Dafür spricht eine Analyse unter US-Veteranen.

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.