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Magnetic Resonance Materials in Physics, Biology and Medicine

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30.10.2018 | Research Article

Cardiac- versus diaphragm-based respiratory navigation for proton spectroscopy of the heart

verfasst von: Mareike Gastl, Sophie M. Peereboom, Maximilian Fuetterer, Florian Boenner, Malte Kelm, Robert Manka, Sebastian Kozerke

Erschienen in: Magnetic Resonance Materials in Physics, Biology and Medicine | Ausgabe 2/2019

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Abstract

Objectives

To study inter-individual differences of the relation between diaphragm and heart motion, the objective of the present study was to implement respiratory navigation on the heart and compare it against the established method of navigator gating on the diaphragm for single-voxel cardiac ¹H-MRS.

Materials and methods

¹H-MRS was performed on a 1.5T system in 19 healthy volunteers of mixed age (range 24–75 years). Spectra were recorded in a 6–8 ml voxel in the ventricular septum using a PRESS (point-resolved spectroscopy) sequence and ECG gating. Water-unsuppressed data acquired with pencil beam navigation on the heart were compared to data with navigation on the diaphragm. Water-suppressed data were obtained to assess triglyceride-to-water ratios.

Results

Water phase and amplitude fluctuations for cardiac versus diaphragm navigation did not reveal significant differences. Both navigator positions provided comparable triglyceride-to-water ratios and gating efficiencies (coefficient of variation (CoV) 7.0%). The cardiac navigator showed a good reproducibility (CoV 5.2%).

Discussion

Respiratory navigation on the heart does not convey an advantage over diaphragm-based navigator gating for cardiac ¹H-MRS, but also no disadvantage. Consequently, cardiac and diaphragm respiratory navigation may be used interchangeably.

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Titel: Cardiac- versus diaphragm-based respiratory navigation for proton spectroscopy of the heart
verfasst von: Mareike Gastl
Sophie M. Peereboom
Maximilian Fuetterer
Florian Boenner
Malte Kelm
Robert Manka
Sebastian Kozerke
Publikationsdatum: 30.10.2018
Verlag: Springer International Publishing
Erschienen in: Magnetic Resonance Materials in Physics, Biology and Medicine / Ausgabe 2/2019
Print ISSN: 0968-5243
Elektronische ISSN: 1352-8661
DOI: https://doi.org/10.1007/s10334-018-0711-y

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Cardiac- versus diaphragm-based respiratory navigation for proton spectroscopy of the heart

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Materials and methods

Results

Discussion

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Springer Medizin

Abstract

Objectives

Materials and methods

Results

Discussion

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