A 71-year-old patient underwent trans-bronchial needle aspiration (TBNA) from mediastinal lymph nodes using endo-bronchial ultrasound (EBUS). The procedure was performed under conscious intravenous sedation through a peripheral vein, using a 21-gauge needle and was associated with only minimal bleeding. After the procedure, he remained comatose. CT angiography revealed diffuse cerebral air emboli (Fig. 1) and ruled out pneumothorax and pneumomediastinum. Echocardiography using color Doppler and bubbles ruled out PFO.
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