Background
Materials and methods
Study population and specimen collection
PCR and sequencing
Phylogenetic analysis
Statistical analysis
Results
Characteristics of the study population
HPV52 (sub)lineages | Normal (n = 57) | CIN1(n = 17) | CIN2(n = 16) | CIN3(n = 20) | Cancer (n = 0) | Total (n = 110) |
---|---|---|---|---|---|---|
A1
|
39(68.4%)
|
13(76.5%)
|
12(75.0%)
|
17(85.0)
|
0
|
81(73.6%)
|
33CNTZ01 | 36(63.2%) | 12(70.6%) | 11(68.8%) | 15(75.0%) | 0 | 74(67.3%) |
33CNTZ02 | 0 | 1(5.9%) | 1(6.3%) | 1(5.0%) | 0 | 3(2.7%) |
33CNTZ05 | 1(1.8%) | 0 | 0 | 0 | 0 | 1(0.9%) |
33CNTZ08 | 1(1.8%) | 0 | 0 | 1(5.0%) | 0 | 2(1.8%) |
33CNTZ09 | 1(1.8%) | 0 | 0 | 0 | 0 | 1(0.9%) |
A2
|
0
|
0
|
1(6.3%)
|
0
|
0
|
1(0.9%)
|
33CNTZ10 | 0 | 0 | 1(6.3%) | 0 | 0 | 1(0.9%) |
A3
|
18(31.6%)
|
4(23.5%)
|
3(18.7%)
|
3(15.0%)
|
0
|
28(25.5%)
|
33CNTZ11 | 13(22.8%) | 3(17.6%) | 3(18.7%) | 3(15.0%) | 0 | 22(20.0%) |
33CNTZ12 | 1(1.8%) | 1(5.9%) | 0 | 0 | 0 | 2(1.8%) |
33CNTZ13 | 2(3.5%) | 0 | 0 | 0 | 0 | 2(1.8%) |
33CNTZ14 | 1(1.8%) | 0 | 0 | 0 | 0 | 1(0.9%) |
33CNTZ15 | 1(1.8%) | 0 | 0 | 0 | 0 | 1(1.8%) |