GCTs are rare tumors and are quite rare in the cervical spine. Various treatment options such as surgery, radiotherapy, embolization, cryotherapy, and chemical adjuvants are used for spinal GCTs. Denosumab has been used in adjuvant therapy in recent years [
9]. The aim of the treatment is to remove the tumor and prevent its recurrence while avoiding neurological structure damage and spinal integrity deterioration [
10‐
13]. Although total en bloc resection is the best treatment method, it may not be possible as in other long bones due to reasons such as spinal cord injury during surgery, large vessel injury (thoracic aorta in the upper thoracal region, between T1–T4, ductus thoracicus and vertebral artery in the cervical region) due to blunt dissection, excessive bleeding, development of instability due to spinal osteotomies, and contamination during removal of the tumor cells, especially in the peduncle [
14,
15]. Good results were reported with en bloc resection to decrease local recurrence in vertebral tumors by Boriani et al. [
16]. Martin et al. recommended preoperative embolization followed by lesion resection for big lesions and en bloc resection in appropriate cases [
10]. Although Marcove et al. [
17] reported good results with cryotherapy, Leggon et al. [
18] encountered a high local recurrence rate of 62% with cryotherapy followed by curettage. Radiotherapy (RT) is an option to decrease postoperative recurrence in GCTs. However, discussion continues on the development of myelopathy and sarcoma due to radiotherapy [
19,
20]. Yang et al. reported sarcomatous changes in one of their three cases following postoperative RT [
13]. RT should therefore mostly be reserved for recurring lesions [
8,
13].
Curettage can be used for small lesions limited to the anterior cervical column, and anterior stabilization can be used for lesions limited to the vertebral corpus in cervical spine GCTs [
11,
21,
22]. Surgery is performed in two stages as anterior and posterior for cases undergoing large excision. Anterior and posterior fusion is used to prevent instability after the excision [
21,
23].
It is difficult to predict the prognosis in GCT cases as the recurrence rate is 11–50% even with the best treatment method of en bloc resection [
8,
10‐
12,
24]. Local recurrences are most commonly seen in the first 3 years [
8]. The local recurrence rate is 22–42% for all cases, but spinal GCT recurrence rates are from small series as spinal involvement by this disorder is rare [
11,
25]. There is also no definite treatment scheme. Although our case had a cervical spine lesion extending posteriorly from the corpus, the vertebral corpus lesion was removed en bloc with a pure anterior approach and the lateral mass extension was excised with intracavitary curettage. A second surgery was therefore not required. Since radiotherapy use in the postoperative period is controversial, we decided not to administer radiotherapy to the patient after consulting with the radiation oncology department.